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Items: 1 to 50 of 83

1.

Immune Thrombocytopenia-A Disease or a Group of Disorders? Where Do We Stand in 2019?

Bakchoul T.

Hamostaseologie. 2019 Aug;39(3):225-226. doi: 10.1055/s-0039-1693660. Epub 2019 Aug 7. No abstract available.

PMID:
31390662
2.

Platelet dysfunction caused by a novel thromboxane A2 receptor mutation and congenital thrombocytopenia in a case of mild bleeding.

Bugert P, Fischer L, Althaus K, Knöfler R, Bakchoul T.

Platelets. 2019 Aug 7:1-4. doi: 10.1080/09537104.2019.1652264. [Epub ahead of print]

PMID:
31389738
3.

Autoimmune Heparin-Induced Thrombocytopenia after Transcatheter Aortic Valve Implantation: Successful Treatment with Adjunct High-Dose Intravenous Immunoglobulin.

Bakchoul T, Borst O, Riessen R, Lucic J, Gawaz M, Althaus K, Aidery P.

TH Open. 2019 Jun 28;3(2):e200-e202. doi: 10.1055/s-0039-1692990. eCollection 2019 Apr.

4.

Use of Targeted High-Throughput Sequencing for Genetic Classification of Patients with Bleeding Diathesis and Suspected Platelet Disorder.

Andres O, König EM, Althaus K, Bakchoul T, Bugert P, Eber S, Knöfler R, Kunstmann E, Manukjan G, Meyer O, Strauß G, Streif W, Thiele T, Wiegering V, Klopocki E, Schulze H; THROMKIDplus Study Group of the Society of Paediatric Oncology Haematology (Gesellschaft für Pädiatrische Onkologie und Hämatologie, GPOH) and the Society of Thrombosis Haemostasis Research (Gesellschaft für Thrombose- und Hämostaseforschung, GTH) .

TH Open. 2018 Dec 30;2(4):e445-e454. doi: 10.1055/s-0038-1676813. eCollection 2018 Oct.

5.

Evaluation of a flow cytometer-based functional assay using platelet-rich plasma in the diagnosis of heparin-induced thrombocytopenia.

Althaus K, Pelzl L, Hidiatov O, Amiral J, Marini I, Bakchoul T.

Thromb Res. 2019 Aug;180:55-61. doi: 10.1016/j.thromres.2019.05.016. Epub 2019 May 31.

PMID:
31220752
6.

Preformed Donor-Specific HLA Antibodies in Living and Deceased Donor Transplantation: A Multicenter Study.

Ziemann M, Altermann W, Angert K, Arns W, Bachmann A, Bakchoul T, Banas B, von Borstel A, Budde K, Ditt V, Einecke G, Eisenberger U, Feldkamp T, Görg S, Guthoff M, Habicht A, Hallensleben M, Heinemann FM, Hessler N, Hugo C, Kaufmann M, Kauke T, Koch M, König IR, Kurschat C, Lehmann C, Marget M, Mühlfeld A, Nitschke M, Pego da Silva L, Quick C, Rahmel A, Rath T, Reinke P, Renders L, Sommer F, Spriewald B, Staeck O, Stippel D, Süsal C, Thiele B, Zecher D, Lachmann N.

Clin J Am Soc Nephrol. 2019 Jul 5;14(7):1056-1066. doi: 10.2215/CJN.13401118. Epub 2019 Jun 18.

PMID:
31213508
7.

Standardization of Light Transmission Aggregometry for Diagnosis of Platelet Disorders: An Inter-Laboratory External Quality Assessment.

Althaus K, Zieger B, Bakchoul T, Jurk K; THROMKID-Plus Studiengruppe der Gesellschaft für Thrombose- und Hämostaseforschung (GTH) und der Gesellschaft für Pädiatrische Onkologie und Hämatologie (GPOH).

Thromb Haemost. 2019 Jul;119(7):1154-1161. doi: 10.1055/s-0039-1688791. Epub 2019 Jun 2.

PMID:
31154663
8.

Postnatal intervention for the treatment of FNAIT: a systematic review.

Baker JM, Shehata N, Bussel J, Murphy MF, Greinacher A, Bakchoul T, Massey E, Lieberman L, Landry D, Tanael S, Arnold DM, Baidya S, Bertrand G, Kjaer M, Kaplan C, Kjeldsen-Kragh J, Oepkes D, Savoia H, Ryan G, Hume H; International Collaboration for Transfusion Medicine Guidelines (ICTMG).

J Perinatol. 2019 Oct;39(10):1329-1339. doi: 10.1038/s41372-019-0360-7. Epub 2019 Apr 10. Review.

PMID:
30971767
9.

Glycoprotein V is a relevant immune target in patients with immune thrombocytopenia.

Vollenberg R, Jouni R, Norris PAA, Burg-Roderfeld M, Cooper N, Rummel MJ, Bein G, Marini I, Bayat B, Burack R, Lazarus AH, Bakchoul T, Sachs UJ.

Haematologica. 2019 Jun;104(6):1237-1243. doi: 10.3324/haematol.2018.211086. Epub 2019 Mar 28.

10.

Fetal and neonatal alloimmune thrombocytopenia: recommendations for evidence-based practice, an international approach.

Lieberman L, Greinacher A, Murphy MF, Bussel J, Bakchoul T, Corke S, Kjaer M, Kjeldsen-Kragh J, Bertrand G, Oepkes D, Baker JM, Hume H, Massey E, Kaplan C, Arnold DM, Baidya S, Ryan G, Savoia H, Landry D, Shehata N; International Collaboration for Transfusion Medicine Guidelines (ICTMG).

Br J Haematol. 2019 May;185(3):549-562. doi: 10.1111/bjh.15813. Epub 2019 Mar 3.

PMID:
30828796
11.

Pathophysiology of Autoimmune Thrombocytopenia: Current Insight with a Focus on Thrombopoiesis.

Marini I, Bakchoul T.

Hamostaseologie. 2019 Aug;39(3):227-237. doi: 10.1055/s-0039-1678732. Epub 2019 Feb 25.

PMID:
30802916
12.

An international external quality assessment for laboratory diagnosis of heparin-induced thrombocytopenia.

Eekels JJM, Althaus K, Bakchoul T, Kroll H, Kiefel V, Nazy I, Lee LS, Sachs U, Warkentin TE, Greinacher A.

J Thromb Haemost. 2019 Mar;17(3):525-531. doi: 10.1111/jth.14383. Epub 2019 Feb 20.

PMID:
30640980
13.

Screening and evaluation of potential recipients and donors for living donor uterus transplantation: results from a single-center observational study.

Taran FA, Schöller D, Rall K, Nadalin S, Königsrainer A, Henes M, Bösmüller H, Fend F, Nikolaou K, Notohamiprodjo M, Grasshoff C, Heim E, Zipfel S, Schäffeler N, Bakchoul T, Heyne N, Guthoff M, Krämer B, Reisenauer C, Hoopmann M, Kagan KO, Brännström M, Wallwiener D, Brucker SY.

Fertil Steril. 2019 Jan;111(1):186-193. doi: 10.1016/j.fertnstert.2018.09.010.

PMID:
30611405
14.

Maternal HPA-1a antibody level and its role in predicting the severity of Fetal/Neonatal Alloimmune Thrombocytopenia: a systematic review.

Kjaer M, Bertrand G, Bakchoul T, Massey E, Baker JM, Lieberman L, Tanael S, Greinacher A, Murphy MF, Arnold DM, Baidya S, Bussel J, Hume H, Kaplan C, Oepkes D, Ryan G, Savoia H, Shehata N, Kjeldsen-Kragh J; International Collaboration for Transfusion Medicine Guidelines.

Vox Sang. 2019 Jan;114(1):79-94. doi: 10.1111/vox.12725. Epub 2018 Nov 22.

PMID:
30565711
15.

Drug-associated thrombocytopenia.

Bakchoul T, Marini I.

Hematology Am Soc Hematol Educ Program. 2018 Nov 30;2018(1):576-583. doi: 10.1182/asheducation-2018.1.576. Review.

PMID:
30504360
16.

Dual-energy CT for liver iron quantification in patients with haematological disorders.

Werner S, Krauss B, Haberland U, Bongers M, Starke U, Bakchoul T, Enkel S, Nikolaou K, Horger M.

Eur Radiol. 2019 Jun;29(6):2868-2877. doi: 10.1007/s00330-018-5785-4. Epub 2018 Nov 7.

PMID:
30406312
17.

Investigations for fetal and neonatal alloimmune thrombocytopenia: communication from the SSC of the ISTH.

Petermann R, Bakchoul T, Curtis BR, Mullier F, Miyata S, Arnold DM; Subcommittee on Platelet Immunology.

J Thromb Haemost. 2018 Dec;16(12):2526-2529. doi: 10.1111/jth.14294. Epub 2018 Nov 1. No abstract available.

PMID:
30382606
18.

Cold storage of platelets in additive solution: the impact of residual plasma in apheresis platelet concentrates.

Marini I, Aurich K, Jouni R, Nowak-Harnau S, Hartwich O, Greinacher A, Thiele T, Bakchoul T.

Haematologica. 2019 Jan;104(1):207-214. doi: 10.3324/haematol.2018.195057. Epub 2018 Aug 16.

19.

International Forum on GMP-grade human platelet lysate for cell propagation: summary.

Strunk D, Lozano M, Marks DC, Loh YS, Gstraunthaler G, Schennach H, Rohde E, Laner-Plamberger S, Öller M, Nystedt J, Lotfi R, Rojewski M, Schrezenmeier H, Bieback K, Schäfer R, Bakchoul T, Waidmann M, Jonsdottir-Buch SM, Montazeri H, Sigurjonsson OE, Iudicone P, Fioravanti D, Pierelli L, Introna M, Capelli C, Falanga A, Takanashi M, Lόpez-Villar O, Burnouf T, Reems JA, Pierce J, Preslar AM, Schallmoser K.

Vox Sang. 2018 Jan;113(1):80-87. doi: 10.1111/vox.12593. Epub 2017 Oct 26. No abstract available.

PMID:
29076169
20.

International Forum on GMP-grade human platelet lysate for cell propagation.

Strunk D, Lozano M, Marks DC, Loh YS, Gstraunthaler G, Schennach H, Rohde E, Laner-Plamberger S, Öller M, Nystedt J, Lotfi R, Rojewski M, Schrezenmeier H, Bieback K, Schäfer R, Bakchoul T, Waidmann M, Jonsdottir-Buch SM, Montazeri H, Sigurjonsson OE, Iudicone P, Fioravanti D, Pierelli L, Introna M, Capelli C, Falanga A, Takanashi M, López-Villar O, Burnouf T, Reems JA, Pierce J, Preslar AM, Schallmoser K.

Vox Sang. 2018 Jan;113(1):e1-e25. doi: 10.1111/vox.12594. Epub 2017 Oct 25. No abstract available.

PMID:
29071726
21.

Magnetic Nanoparticle Labeling of Human Platelets from Platelet Concentrates for Recovery and Survival Studies.

Aurich K, Wesche J, Palankar R, Schlüter R, Bakchoul T, Greinacher A.

ACS Appl Mater Interfaces. 2017 Oct 11;9(40):34666-34673. doi: 10.1021/acsami.7b10113. Epub 2017 Sep 29.

PMID:
28945336
22.

Recessive grey platelet-like syndrome with unaffected erythropoiesis in the absence of the splice isoform GFI1B-p37.

Schulze H, Schlagenhauf A, Manukjan G, Beham-Schmid C, Andres O, Klopocki E, König EM, Haidl H, Panzer S, Althaus K, Muntean WE, Schwinger W, Urban C, Greinacher A, Bakchoul T, Seidel MG.

Haematologica. 2017 Sep;102(9):e375-e378. doi: 10.3324/haematol.2017.167957. Epub 2017 May 26. No abstract available.

23.

Diagnosis of inherited platelet disorders on a blood smear: a tool to facilitate worldwide diagnosis of platelet disorders.

Greinacher A, Pecci A, Kunishima S, Althaus K, Nurden P, Balduini CL, Bakchoul T.

J Thromb Haemost. 2017 Jul;15(7):1511-1521. doi: 10.1111/jth.13729. Epub 2017 Jun 4.

24.

Evaluation of a diagnostic algorithm for Heparin-Induced Thrombocytopenia.

Farm M, Bakchoul T, Frisk T, Althaus K, Odenrick A, Norberg EM, Berndtsson M, Antovic JP.

Thromb Res. 2017 Apr;152:77-81. doi: 10.1016/j.thromres.2017.02.015. Epub 2017 Feb 24.

PMID:
28262567
25.

Antenatal management in fetal and neonatal alloimmune thrombocytopenia: a systematic review.

Winkelhorst D, Murphy MF, Greinacher A, Shehata N, Bakchoul T, Massey E, Baker J, Lieberman L, Tanael S, Hume H, Arnold DM, Baidya S, Bertrand G, Bussel J, Kjaer M, Kaplan C, Kjeldsen-Kragh J, Oepkes D, Ryan G.

Blood. 2017 Mar 16;129(11):1538-1547. doi: 10.1182/blood-2016-10-739656. Epub 2017 Jan 27. Review.

PMID:
28130210
26.

Heparin-induced multi-electrode aggregometry method for heparin-induced thrombocytopenia testing: communication from the SSC of the ISTH.

Morel-Kopp MC, Mullier F, Gkalea V, Bakchoul T, Minet V, Elalamy I, Ward CM; subcommittee on platelet immunology.

J Thromb Haemost. 2016 Dec;14(12):2548-2552. doi: 10.1111/jth.13516. Epub 2016 Nov 19. No abstract available.

27.

Heparin-induced thrombocytopenia in 2017 and beyond.

Bakchoul T, Greinacher A, Warkentin TE.

Thromb Haemost. 2016 Oct 28;116(5):781-782. Epub 2016 Oct 13. No abstract available.

PMID:
27734071
28.

Clinical and laboratory tests for the diagnosis of heparin-induced thrombocytopenia.

Nagler M, Bakchoul T.

Thromb Haemost. 2016 Oct 28;116(5):823-834. Epub 2016 Sep 8.

PMID:
27604316
29.

Platelet activation in the presence of neutral protamine Hagedorn insulin: a new feature of antibodies against protamine/heparin complexes.

Zöllner H, Jouni R, Panzer S, Khadour A, Janzen L, Wesche J, Ten Berg M, Schellong S, Heinken A, Greinacher A, Bakchoul T.

J Thromb Haemost. 2017 Jan;15(1):176-184. doi: 10.1111/jth.13547. Epub 2016 Nov 30.

30.

Protamine (heparin)-induced thrombocytopenia: a review of the serological and clinical features associated with anti-protamine/heparin antibodies.

Bakchoul T, Jouni R, Warkentin TE.

J Thromb Haemost. 2016 Sep;14(9):1685-95. doi: 10.1111/jth.13405. Epub 2016 Aug 29. Review.

31.

Safe bridging to warfarin in heparin-induced thrombocytopenia.

Bakchoul T, Warkentin TE.

Thromb Res. 2016 Aug;144:226-8. doi: 10.1016/j.thromres.2016.06.025. Epub 2016 Jun 23. No abstract available.

PMID:
27363624
32.

Antiendothelial αvβ3 Antibodies Are a Major Cause of Intracranial Bleeding in Fetal/Neonatal Alloimmune Thrombocytopenia.

Santoso S, Wihadmadyatami H, Bakchoul T, Werth S, Al-Fakhri N, Bein G, Kiefel V, Zhu J, Newman PJ, Bayat B, Sachs UJ.

Arterioscler Thromb Vasc Biol. 2016 Aug;36(8):1517-24. doi: 10.1161/ATVBAHA.116.307281. Epub 2016 Jun 9.

33.

Assessment of human platelet survival in the NOD/SCID mouse model: technical considerations.

Fuhrmann J, Jouni R, Alex J, Zöllner H, Wesche J, Greinacher A, Bakchoul T.

Transfusion. 2016 Jun;56(6):1370-6. doi: 10.1111/trf.13602. Epub 2016 Apr 18.

PMID:
27086568
34.

An update on heparin-induced thrombocytopenia: diagnosis and management.

Bakchoul T.

Expert Opin Drug Saf. 2016 Jun;15(6):787-97. doi: 10.1517/14740338.2016.1165667. Epub 2016 Apr 7. Review.

PMID:
26966871
35.

A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies.

Turro E, Greene D, Wijgaerts A, Thys C, Lentaigne C, Bariana TK, Westbury SK, Kelly AM, Selleslag D, Stephens JC, Papadia S, Simeoni I, Penkett CJ, Ashford S, Attwood A, Austin S, Bakchoul T, Collins P, Deevi SV, Favier R, Kostadima M, Lambert MP, Mathias M, Millar CM, Peerlinck K, Perry DJ, Schulman S, Whitehorn D, Wittevrongel C; BRIDGE-BPD Consortium, De Maeyer M, Rendon A, Gomez K, Erber WN, Mumford AD, Nurden P, Stirrups K, Bradley JR, Raymond FL, Laffan MA, Van Geet C, Richardson S, Freson K, Ouwehand WH.

Sci Transl Med. 2016 Mar 2;8(328):328ra30. doi: 10.1126/scitranslmed.aad7666. Epub 2016 Mar 2.

36.

A gain-of-function variant in DIAPH1 causes dominant macrothrombocytopenia and hearing loss.

Stritt S, Nurden P, Turro E, Greene D, Jansen SB, Westbury SK, Petersen R, Astle WJ, Marlin S, Bariana TK, Kostadima M, Lentaigne C, Maiwald S, Papadia S, Kelly AM, Stephens JC, Penkett CJ, Ashford S, Tuna S, Austin S, Bakchoul T, Collins P, Favier R, Lambert MP, Mathias M, Millar CM, Mapeta R, Perry DJ, Schulman S, Simeoni I, Thys C; BRIDGE-BPD Consortium, Gomez K, Erber WN, Stirrups K, Rendon A, Bradley JR, van Geet C, Raymond FL, Laffan MA, Nurden AT, Nieswandt B, Richardson S, Freson K, Ouwehand WH, Mumford AD.

Blood. 2016 Jun 9;127(23):2903-14. doi: 10.1182/blood-2015-10-675629. Epub 2016 Feb 24.

37.

Congenital macrothrombocytopenia associated with a combination of functional polymorphisms in the TUBB1 gene.

Stächele J, Bakchoul T, Najm J, Felbor U, Knöfler R.

Hamostaseologie. 2015;35 Suppl 1:S18-21.

PMID:
26540125
38.

Further insights into the anti-PF4/heparin IgM immune response.

Krauel K, Schulze A, Jouni R, Hackbarth C, Hietkamp B, Selleng S, Koster A, Jensch I, van der Linde J, Schwertz H, Bakchoul T, Hundt M, Greinacher A.

Thromb Haemost. 2016 Apr;115(4):752-61. doi: 10.1160/TH15-08-0654. Epub 2015 Oct 15.

PMID:
26467272
39.

Mass spectrometric phosphoproteome analysis of small-sized samples of human neutrophils.

Muschter S, Berthold T, Bhardwaj G, Hammer E, Dhople VM, Wesche J, Reil A, Bux J, Bakchoul T, Steil L, Greinacher A, Völker U.

Clin Chim Acta. 2015 Dec 7;451(Pt B):199-207. doi: 10.1016/j.cca.2015.09.030. Epub 2015 Oct 3.

PMID:
26434552
40.

Partially desulfated heparin modulates the interaction between anti-protamine/heparin antibodies and platelets.

Jouni R, Zöllner H, Khadour A, Wesche J, Grotevendt A, Brandt S, Delcea M, Krauel K, Schwertz H, Sachs UJ, Greinacher A, Bakchoul T.

Thromb Haemost. 2016 Jan;115(2):324-32. doi: 10.1160/TH15-07-0539. Epub 2015 Oct 1.

PMID:
26423467
41.

Human neutrophil antigen-3a antibodies induce neutrophil stiffening and conformational activation of CD11b without shedding of L-selectin.

Berthold T, Glaubitz M, Muschter S, Groß S, Palankar R, Reil A, Helm CA, Bakchoul T, Schwertz H, Bux J, Greinacher A, Delcea M.

Transfusion. 2015 Dec;55(12):2939-48. doi: 10.1111/trf.13299. Epub 2015 Sep 10.

PMID:
26361072
42.

Flucloxacillin-induced immune thrombocytopenia.

Jatzlauk G, Althaus K, Strobel U, Kiefel V, Wesche J, Muehlenberg K, Greinacher A, Bakchoul T.

Transfusion. 2016 Jan;56(1):67-72. doi: 10.1111/trf.13284. Epub 2015 Sep 1.

PMID:
26331798
43.

Platelet-activating protamine-heparin-antibodies lead to higher protamine demand in patients undergoing cardiac surgery.

Grieshaber P, Bakchoul T, Wilhelm J, Wagner A, Wollbrück M, Böning A, Sachs U.

J Thorac Cardiovasc Surg. 2015 Oct;150(4):967-73.e1. doi: 10.1016/j.jtcvs.2015.07.057. Epub 2015 Jul 26.

44.

HNA antibody-mediated neutrophil aggregation is dependent on serine protease activity.

Berthold T, Schubert N, Muschter S, Rohr M, Wesche J, Reil A, Bux J, Bakchoul T, Greinacher A.

Vox Sang. 2015 Nov;109(4):366-74. doi: 10.1111/vox.12292. Epub 2015 Jun 17.

PMID:
26084778
45.

Platelet destruction in immune thrombocytopenia. Understanding the mechanisms.

Bakchoul T, Sachs UJ.

Hamostaseologie. 2016 Aug 3;36(3):187-94. doi: 10.5482/HAMO-14-09-0043. Epub 2015 May 18. Review.

PMID:
25982994
46.

Human phenotype ontology annotation and cluster analysis to unravel genetic defects in 707 cases with unexplained bleeding and platelet disorders.

Westbury SK, Turro E, Greene D, Lentaigne C, Kelly AM, Bariana TK, Simeoni I, Pillois X, Attwood A, Austin S, Jansen SB, Bakchoul T, Crisp-Hihn A, Erber WN, Favier R, Foad N, Gattens M, Jolley JD, Liesner R, Meacham S, Millar CM, Nurden AT, Peerlinck K, Perry DJ, Poudel P, Schulman S, Schulze H, Stephens JC, Furie B, Robinson PN, van Geet C, Rendon A, Gomez K, Laffan MA, Lambert MP, Nurden P, Ouwehand WH, Richardson S, Mumford AD, Freson K; BRIDGE-BPD Consortium.

Genome Med. 2015 Apr 9;7(1):36. doi: 10.1186/s13073-015-0151-5. eCollection 2015.

47.

Tolerance of platelet concentrates treated with UVC-light only for pathogen reduction--a phase I clinical trial.

Thiele T, Pohler P, Kohlmann T, Sümnig A, Aurich K, Selleng K, Westphal A, Bakchoul T, Petersmann A, Müller TH, Greinacher A, Seltsam A.

Vox Sang. 2015 Jul;109(1):44-51. doi: 10.1111/vox.12247. Epub 2015 Mar 6.

PMID:
25754418
48.

Recommendations for the use of the non-obese diabetic/severe combined immunodeficiency mouse model in autoimmune and drug-induced thrombocytopenia: communication from the SSC of the ISTH.

Bakchoul T, Fuhrmann J, Chong BH, Bougie D, Aster R; Subcommittee on Platelet Immunology.

J Thromb Haemost. 2015 May;13(5):872-5. doi: 10.1111/jth.12879. Epub 2015 Mar 28. No abstract available.

49.

Severe and persistent heparin-induced thrombocytopenia despite fondaparinux treatment.

Tvito A, Bakchoul T, Rowe JM, Greinacher A, Ganzel C.

Am J Hematol. 2015 Jul;90(7):675-8. doi: 10.1002/ajh.23971. Epub 2015 Feb 27. No abstract available.

50.

Recommendations for standardization of laboratory testing for drug-induced immune thrombocytopenia: communication from the SSC of the ISTH.

Arnold DM, Curtis BR, Bakchoul T; Platelet Immunology Scientific Subcommittee of the International Society on Thrombosis and Hemostasis.

J Thromb Haemost. 2015 Apr;13(4):676-8. doi: 10.1111/jth.12852. Epub 2015 Feb 17. No abstract available.

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