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Items: 21


Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells.

Bajbouj K, Shafarin J, Taneera J, Hamad M.

Biology (Basel). 2020 Apr 1;9(4). pii: E68. doi: 10.3390/biology9040068.


Reduced Expression of Chl1 gene Impairs Insulin Secretion by Down-Regulating the Expression of Key Molecules of β-cell Function.

Taneera J, Dhaiban S, Hachim M, Mohammed AK, Mukhopadhyay D, Bajbouj K, Hamoudi R, Salehi A, Hamad M.

Exp Clin Endocrinol Diabetes. 2019 Oct 15. doi: 10.1055/a-1014-2544. [Epub ahead of print]


Quercetin modulates signaling pathways and induces apoptosis in cervical cancer cells.

Kedhari Sundaram M, Raina R, Afroze N, Bajbouj K, Hamad M, Haque S, Hussain A.

Biosci Rep. 2019 Aug 13;39(8). pii: BSR20190720. doi: 10.1042/BSR20190720. Print 2019 Aug 30.


Estrogen-dependent disruption of intracellular iron metabolism augments the cytotoxic effects of doxorubicin in select breast and ovarian cancer cells.

Bajbouj K, Shafarin J, Hamad M.

Cancer Manag Res. 2019 May 23;11:4655-4668. doi: 10.2147/CMAR.S204852. eCollection 2019.


The Case for an Estrogen-iron Axis in Health and Disease.

Hamad M, Bajbouj K, Taneera J.

Exp Clin Endocrinol Diabetes. 2019 Apr 12. doi: 10.1055/a-0885-1677. [Epub ahead of print]


High-Dose Deferoxamine Treatment Disrupts Intracellular Iron Homeostasis, Reduces Growth, and Induces Apoptosis in Metastatic and Nonmetastatic Breast Cancer Cell Lines.

Bajbouj K, Shafarin J, Hamad M.

Technol Cancer Res Treat. 2018 Jan 1;17:1533033818764470. doi: 10.1177/1533033818764470.


Elevated Levels of Estrogen Suppress Hepcidin Synthesis and Enhance Serum Iron Availability in Premenopausal Women.

Bajbouj K, Shafarin J, Allam H, Madkour M, Awadallah S, El-Serafy A, Sandeep D, Hamad M.

Exp Clin Endocrinol Diabetes. 2018 Jul;126(7):453-459. doi: 10.1055/s-0043-124077. Epub 2018 Feb 2.


Estrogen-induced disruption of intracellular iron metabolism leads to oxidative stress, membrane damage, and cell cycle arrest in MCF-7 cells.

Bajbouj K, Shafarin J, Abdalla MY, Ahmad IM, Hamad M.

Tumour Biol. 2017 Oct;39(10):1010428317726184. doi: 10.1177/1010428317726184.


Defective autophagosome formation in p53-null colorectal cancer reinforces crocin-induced apoptosis.

Amin A, Bajbouj K, Koch A, Gandesiri M, Schneider-Stock R.

Int J Mol Sci. 2015 Jan 9;16(1):1544-61. doi: 10.3390/ijms16011544.


Carnosol induces ROS-mediated beclin1-independent autophagy and apoptosis in triple negative breast cancer.

Al Dhaheri Y, Attoub S, Ramadan G, Arafat K, Bajbouj K, Karuvantevida N, AbuQamar S, Eid A, Iratni R.

PLoS One. 2014 Oct 9;9(10):e109630. doi: 10.1371/journal.pone.0109630. eCollection 2014.


ATF2 knockdown reinforces oxidative stress-induced apoptosis in TE7 cancer cells.

Walluscheck D, Poehlmann A, Hartig R, Lendeckel U, Schönfeld P, Hotz-Wagenblatt A, Reissig K, Bajbouj K, Roessner A, Schneider-Stock R.

J Cell Mol Med. 2013 Aug;17(8):976-88. doi: 10.1111/jcmm.12071. Epub 2013 Jun 25.


The anticancer effect of saffron in two p53 isogenic colorectal cancer cell lines.

Bajbouj K, Schulze-Luehrmann J, Diermeier S, Amin A, Schneider-Stock R.

BMC Complement Altern Med. 2012 May 28;12:69. doi: 10.1186/1472-6882-12-69.


P53-dependent antiproliferative and pro-apoptotic effects of trichostatin A (TSA) in glioblastoma cells.

Bajbouj K, Mawrin C, Hartig R, Schulze-Luehrmann J, Wilisch-Neumann A, Roessner A, Schneider-Stock R.

J Neurooncol. 2012 May;107(3):503-16. doi: 10.1007/s11060-011-0791-2. Epub 2012 Jan 20.


Epigenetic mechanisms of plant-derived anticancer drugs.

Schneider-Stock R, Ghantous A, Bajbouj K, Saikali M, Darwiche N.

Front Biosci (Landmark Ed). 2012 Jan 1;17:129-73. Review.


Saffron: a potential candidate for a novel anticancer drug against hepatocellular carcinoma.

Amin A, Hamza AA, Bajbouj K, Ashraf SS, Daoud S.

Hepatology. 2011 Sep 2;54(3):857-67. doi: 10.1002/hep.24433. Epub 2011 Jul 19.


Apoptosis signalling activated by TNF in the lower gastrointestinal tract--review.

Benderska N, Chakilam S, Hugle M, Ivanovska J, Gandesiri M, Schulze-Luhrmann J, Bajbouj K, Croner R, Schneider-Stock R.

Curr Pharm Biotechnol. 2012 Sep;13(11):2248-58. Review.


Cutting edge: Chk1 directs senescence and mitotic catastrophe in recovery from G₂ checkpoint arrest.

Poehlmann A, Habold C, Walluscheck D, Reissig K, Bajbouj K, Ullrich O, Hartig R, Gali-Muhtasib H, Diestel A, Roessner A, Schneider-Stock R.

J Cell Mol Med. 2011 Jul;15(7):1528-41. doi: 10.1111/j.1582-4934.2010.01143.x.


RETRACTED: Identification of phosphorylated p38 as a novel DAPK-interacting partner during TNFalpha-induced apoptosis in colorectal tumor cells.

Bajbouj K, Poehlmann A, Kuester D, Drewes T, Haase K, Hartig R, Teller A, Kliche S, Walluscheck D, Ivanovska J, Chakilam S, Ulitzsch A, Bommhardt U, Leverkus M, Roessner A, Schneider-Stock R.

Am J Pathol. 2009 Aug;175(2):557-70. doi: 10.2353/ajpath.2009.080853. Epub 2009 Jul 23. Retraction in: Am J Pathol. 2017 Jan;187(1):225.


Thymoquinone triggers inactivation of the stress response pathway sensor CHEK1 and contributes to apoptosis in colorectal cancer cells.

Gali-Muhtasib H, Kuester D, Mawrin C, Bajbouj K, Diestel A, Ocker M, Habold C, Foltzer-Jourdainne C, Schoenfeld P, Peters B, Diab-Assaf M, Pommrich U, Itani W, Lippert H, Roessner A, Schneider-Stock R.

Cancer Res. 2008 Jul 15;68(14):5609-18. doi: 10.1158/0008-5472.CAN-08-0884.


Trichostatin A causes p53 to switch oxidative-damaged colorectal cancer cells from cell cycle arrest into apoptosis.

Habold C, Poehlmann A, Bajbouj K, Hartig R, Korkmaz KS, Roessner A, Schneider-Stock R.

J Cell Mol Med. 2008 Apr;12(2):607-21. doi: 10.1111/j.1582-4934.2007.00136.x. Erratum in: J Cell Mol Med. 2008 Aug;12(4):1421.


Lack of p53 augments thymoquinone-induced apoptosis and caspase activation in human osteosarcoma cells.

Roepke M, Diestel A, Bajbouj K, Walluscheck D, Schonfeld P, Roessner A, Schneider-Stock R, Gali-Muhtasib H.

Cancer Biol Ther. 2007 Feb;6(2):160-9. Epub 2007 Feb 5.


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