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Items: 1 to 50 of 62

1.

Protein kinase N1 critically regulates cerebellar development and long-term function.

zur Nedden S, Eith R, Schwarzer C, Zanetti L, Seitter H, Fresser F, Koschak A, Cameron AJ, Parker PJ, Baier G, Baier-Bitterlich G.

J Clin Invest. 2018 May 1;128(5):2076-2088. doi: 10.1172/JCI96165. Epub 2018 Apr 16.

2.

Protein Kinase C-Related Kinase (PKN/PRK). Potential Key-Role for PKN1 in Protection of Hypoxic Neurons.

Thauerer B, Zur Nedden S, Baier-Bitterlich G.

Curr Neuropharmacol. 2014 May;12(3):213-8. doi: 10.2174/1570159X11666131225000518.

3.

LAMTOR2-mediated modulation of NGF/MAPK activation kinetics during differentiation of PC12 cells.

Thauerer B, Voegele P, Hermann-Kleiter N, Thuille N, de Araujo ME, Offterdinger M, Baier G, Huber LA, Baier-Bitterlich G.

PLoS One. 2014 Apr 21;9(4):e95863. doi: 10.1371/journal.pone.0095863. eCollection 2014.

4.

Purine nucleosides: endogenous neuroprotectants in hypoxic brain.

Thauerer B, Zur Nedden S, Baier-Bitterlich G.

J Neurochem. 2012 May;121(3):329-42. doi: 10.1111/j.1471-4159.2012.07692.x. Epub 2012 Mar 14. Review.

5.

Vital role of protein kinase C-related kinase in the formation and stability of neurites during hypoxia.

Thauerer B, zur Nedden S, Baier-Bitterlich G.

J Neurochem. 2010 Apr;113(2):432-46. doi: 10.1111/j.1471-4159.2010.06624.x. Epub 2010 Jan 28.

6.

p42/44 MAPK is an essential effector for purine nucleoside-mediated neuroprotection of hypoxic PC12 cells and primary cerebellar granule neurons.

Tomaselli B, Nedden SZ, Podhraski V, Baier-Bitterlich G.

Mol Cell Neurosci. 2008 Aug;38(4):559-68. doi: 10.1016/j.mcn.2008.05.004. Epub 2008 May 17.

PMID:
18585057
7.

HIF-1 alpha is an essential effector for purine nucleoside-mediated neuroprotection against hypoxia in PC12 cells and primary cerebellar granule neurons.

zur Nedden S, Tomaselli B, Baier-Bitterlich G.

J Neurochem. 2008 Jun;105(5):1901-14. doi: 10.1111/j.1471-4159.2008.05275.x. Epub 2008 Feb 4.

8.

Purine nucleoside-mediated protection of chemical hypoxia-induced neuronal injuries involves p42/44 MAPK activation.

Tomaselli B, Podhraski V, Heftberger V, Böck G, Baier-Bitterlich G.

Neurochem Int. 2005 Jun;46(7):513-21.

PMID:
15843045
9.

Purine nucleosides support the neurite outgrowth of primary rat cerebellar granule cells after hypoxia.

Böcklinger K, Tomaselli B, Heftberger V, Podhraski V, Bandtlow C, Baier-Bitterlich G.

Eur J Cell Biol. 2004 Mar;83(2):51-4.

PMID:
15146976
10.

Evidence of functional modulation of the MEKK/JNK/cJun signaling cascade by the low density lipoprotein receptor-related protein (LRP).

Lutz C, Nimpf J, Jenny M, Boecklinger K, Enzinger C, Utermann G, Baier-Bitterlich G, Baier G.

J Biol Chem. 2002 Nov 8;277(45):43143-51. Epub 2002 Aug 21.

11.

7,8-Dihydroneopterin induces apoptosis of Jurkat T-lymphocytes via a Bcl-2-sensitive pathway.

Enzinger C, Wirleitner B, Lutz C, Böck G, Tomaselli B, Baier G, Fuchs D, Baier-Bitterlich G.

Eur J Cell Biol. 2002 Apr;81(4):197-202.

PMID:
12018387
12.

Reduced pteridine derivatives induce apoptosis in PC12 cells.

Enzinger C, Wirleitner B, Spöttl N, Böck G, Fuchs D, Baier-Bitterlich G.

Neurochem Int. 2002 Jul;41(1):71-8.

PMID:
11918974
13.

Influence of cytokines tumor necrosis factor-alpha and interferon-gamma on signaling cascades associated with apoptosis in rat PC12 cells.

Enzinger C, Wirleitner B, Böck G, Baier-Bitterlich G, Fuchs D.

Neurosci Lett. 2001 Dec 28;316(3):157-60.

PMID:
11744226
14.

Induction of apoptosis by 7,8-dihydroneopterin: involvement of radical formation.

Wirleitner B, Czaputa R, Oettl K, Böck G, Widner B, Reibnegger G, Baier G, Fuchs D, Baier-Bitterlich G.

Immunobiology. 2001 May;203(4):629-41.

PMID:
11402497
15.

Cellular immune activation, neopterin production, tryptophan degradation and the development of immunodeficiency.

Widner B, Wirleitner B, Baier-Bitterlich G, Weiss G, Fuchs D.

Arch Immunol Ther Exp (Warsz). 2000;48(4):251-8. Review.

PMID:
11059641
16.

Enhanced tryptophan degradation in systemic lupus erythematosus.

Widner B, Sepp N, Kowald E, Ortner U, Wirleitner B, Fritsch P, Baier-Bitterlich G, Fuchs D.

Immunobiology. 2000 Apr;201(5):621-30.

PMID:
10834318
17.

Reduced pteridine derivatives induce apoptosis in human neuronal NT2/HNT cells.

Spöttl N, Wirleitner B, Böck G, Widner B, Fuchs D, Baier-Bitterlich G.

Immunobiology. 2000 Jan;201(3-4):478-91.

PMID:
10776802
18.

Synergistic action of protein kinase C theta and calcineurin is sufficient for Fas ligand expression and induction of a crmA-sensitive apoptosis pathway in Jurkat T cells.

Villunger A, Ghaffari-Tabrizi N, Tinhofer I, Krumböck N, Bauer B, Schneider T, Kasibhatla S, Greil R, Baier-Bitterlich G, Uberall F, Green DR, Baier G.

Eur J Immunol. 1999 Nov;29(11):3549-61.

19.

Formation of oxygen radicals in solutions of 7,8-dihydroneopterin.

Oettl K, Wirleitner B, Baier-Bitterlich G, Grammer T, Fuchs D, Reibnegger G.

Biochem Biophys Res Commun. 1999 Oct 14;264(1):262-7.

PMID:
10527875
20.

Increased neopterin concentrations in patients with cancer: indicator of oxidative stress?

Murr C, Fuith LC, Widner B, Wirleitner B, Baier-Bitterlich G, Fuchs D.

Anticancer Res. 1999 May-Jun;19(3A):1721-8. Review.

PMID:
10470106
21.

Evidence that atypical protein kinase C-lambda and atypical protein kinase C-zeta participate in Ras-mediated reorganization of the F-actin cytoskeleton.

Uberall F, Hellbert K, Kampfer S, Maly K, Villunger A, Spitaler M, Mwanjewe J, Baier-Bitterlich G, Baier G, Grunicke HH.

J Cell Biol. 1999 Feb 8;144(3):413-25.

22.

Protein kinase Ctheta, a selective upstream regulator of JNK/SAPK and IL-2 promoter activation in Jurkat T cells.

Ghaffari-Tabrizi N, Bauer B, Villunger A, Baier-Bitterlich G, Altman A, Utermann G, Uberall F, Baier G.

Eur J Immunol. 1999 Jan;29(1):132-42.

23.

Structure and function of HIV-1 and SIV Tat proteins based on carboxy-terminal truncations, chimeric Tat constructs, and NMR modeling.

Baier-Bitterlich G, Tretiakova A, Richardson MW, Khalili K, Jameson B, Rappaport J.

Biomed Pharmacother. 1998;52(10):421-30.

PMID:
9921410
24.

7,8-Dihydroneopterin-induced apoptosis in Jurkat T lymphocytes: a comparison with anti-Fas- and hydrogen peroxide-mediated cell death.

Wirleitner B, Baier-Bitterlich G, Böck G, Widner B, Fuchs D.

Biochem Pharmacol. 1998 Nov 1;56(9):1181-7.

PMID:
9802329
25.

Neopterin induces nitric oxide-dependent apoptosis in rat vascular smooth muscle cells.

Hoffmann G, Kenn S, Wirleitner B, Deetjen C, Frede S, Smolny M, Rieder J, Fuchs D, Baier-Bitterlich G, Schobersberger W.

Immunobiology. 1998 Jul;199(1):63-73.

PMID:
9717668
26.

Neopterin derivatives modulate the nitration of tyrosine by peroxynitrite.

Widner B, Baier-Bitterlich G, Wede I, Wirleitner B, Fuchs D.

Biochem Biophys Res Commun. 1998 Jul 20;248(2):341-6.

PMID:
9675137
27.

Chronic immune stimulation, oxidative stress, and apoptosis in HIV infection.

Baier-Bitterlich G, Fuchs D, Wachter H.

Biochem Pharmacol. 1997 Mar 21;53(6):755-63. Review.

PMID:
9113096
28.

trans-Activation of the HIV type 1 promoter by 7,8-dihydroneopterin in vitro.

Baier-Bitterlich G, Fuchs D, Zangerle R, Baeuerle PA, Werner ER, Fresser F, Uberall F, Baier G, Wachter H.

AIDS Res Hum Retroviruses. 1997 Jan 20;13(2):173-8.

PMID:
9007202
29.

Neopterin derivatives to activate NF-kappa B.

Wirleitner B, Baier-Bitterlich G, Hoffmann G, Schobersberger W, Wachter H, Fuchs D.

Free Radic Biol Med. 1997;23(1):177-9. No abstract available.

PMID:
9165312
30.

Role of 7,8-dihydroneopterin in T-cell apoptosis and HTLV-1 transcription in vitro.

Baier-Bitterlich G, Baier G, Fuchs D, Böck G, Hausen A, Utermann G, Pavelka M, Wachter H.

Oncogene. 1996 Nov 21;13(10):2281-5.

PMID:
8950996
31.

Neopterin and 7,8-dihydroneopterin induce apoptosis in the rat alveolar epithelial cell line L2.

Schobersberger W, Hoffmann G, Hobisch-Hagen P, Bock G, Volkl H, Baier-Bitterlich G, Wirleitner B, Wachter H, Fuchs D.

FEBS Lett. 1996 Nov 18;397(2-3):263-8.

32.

Role of neopterin and 7,8-dihydroneopterin in human immunodeficiency virus infection: marker for disease progression and pathogenic link.

Baier-Bitterlich G, Wachter H, Fuchs D.

J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Oct 1;13(2):184-93. Review.

PMID:
8862284
33.

Streptococcal erythrogenic toxins induce neopterin formation in human peripheral blood mononuclear cells but not in the human myelomonocytoma cell line THP-1.

Murr C, Baier-Bitterlich G, Fuchs D, Gerlach D, Werner-Felmayer G, Dierich MP, Wachter H.

Immunobiology. 1996 Aug;195(3):314-22.

PMID:
8877405
34.

Decreased plasma tryptophan in pregnancy.

Schröcksnadel H, Baier-Bitterlich G, Dapunt O, Wachter H, Fuchs D.

Obstet Gynecol. 1996 Jul;88(1):47-50.

PMID:
8684760
35.

Interferon-gamma and management of infectious diseases.

Baier-Bitterlich G, Wachter H, Fuchs D.

Ann Intern Med. 1996 Jun 15;124(12):1095-6. No abstract available.

PMID:
8633827
36.

Protein kinase C-theta isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes.

Baier-Bitterlich G, Uberall F, Bauer B, Fresser F, Wachter H, Grunicke H, Utermann G, Altman A, Baier G.

Mol Cell Biol. 1996 Apr;16(4):1842-50.

37.

Oxidative stress and apoptosis in HIV infection.

Baier-Bitterlich G, Wachter H, Fuchs D.

Science. 1996 Feb 2;271(5249):582-3. No abstract available.

PMID:
8571116
38.

Soluble Receptors for Tumor Necrosis Factor and Neopterin as Parameters of Cell-Mediated Immune Activation.

Tilz GP, Diez-Ruiz A, Baier-Bitterlich G, Demel U, Wachter H, Fuchs D.

Hematology. 1996;1(2):141-54. doi: 10.1080/10245332.1996.11746298.

PMID:
27406429
39.

7,8-Dihydroneopterin upregulates interferon-gamma promoter in T cells.

Baier-Bitterlich G, Fuchs D, Wachter H.

Immunobiology. 1996;196(4):350-5.

PMID:
9061375
40.

Kynurenine and pteridines in changes of membrane fluidity.

Rudzite V, Jurika E, Fuchs D, Baier-Bitterlich G, Wachter H.

Adv Exp Med Biol. 1996;398:255-61. No abstract available.

PMID:
8906273
41.

Serum tryptophan, kynurenine, and neopterin in patients with Guillain-Barre-syndrome (GBS) and multiple sclerosis (MS).

Rudzite V, Berzinsh J, Grivane I, Fuchs D, Baier-Bitterlich G, Wachter H.

Adv Exp Med Biol. 1996;398:183-7. No abstract available.

PMID:
8906264
42.

Activated cellular immunity and decreased serum tryptophan in healthy pregnancy.

Fuchs D, Schröcksnadel H, Baier-Bitterlich G, Dapunt O, Wachter H.

Adv Exp Med Biol. 1996;398:149-53.

PMID:
8906258
43.

Effects of neopterin-derivatives on H2O2-induced luminol chemiluminescence: mechanistic aspects.

Murr C, Baier-Bitterlich G, Fuchs D, Werner ER, Esterbauer H, Pfleiderer W, Wachter H.

Free Radic Biol Med. 1996;21(4):449-56.

PMID:
8886794
44.

Inhibition of HIV-1 expression by HIV-2.

Rappaport J, Arya SK, Richardson MW, Baier-Bitterlich G, Klotman PE.

J Mol Med (Berl). 1995 Dec;73(12):583-9.

PMID:
8825754
45.

Human immunodeficiency virus infection and porphyria cutanea tarda.

Fuchs D, Baier-Bitterlich G, Wachter H.

Clin Infect Dis. 1995 Dec;21(6):1530-1. No abstract available.

PMID:
8749664
46.

Nitric oxide and AIDS dementia.

Fuchs D, Baier-Bitterlich G, Wachter H.

N Engl J Med. 1995 Aug 24;333(8):521-2. No abstract available.

PMID:
7623891
47.

Effect of neopterin and 7,8-dihydroneopterin on tumor necrosis factor-alpha induced programmed cell death.

Baier-Bitterlich G, Fuchs D, Murr C, Reibnegger G, Werner-Felmayer G, Sgonc R, Böck G, Dierich MP, Wachter H.

FEBS Lett. 1995 May 8;364(2):234-8.

48.

Detection of bacterial pyrogens on the basis of their effects on gamma interferon-mediated formation of neopterin or nitrite in cultured monocyte cell lines.

Werner-Felmayer G, Baier-Bitterlich G, Fuchs D, Hausen A, Murr C, Reibnegger G, Werner ER, Wachter H.

Clin Diagn Lab Immunol. 1995 May;2(3):307-13.

49.

[Neopterin as an immunodiagnostic parameter].

Fuchs D, Baier-Bitterlich G, Hausen A, Murr C, Weiss G, Werner ER, Werner-Felmayer G, Reibnegger G.

Dtsch Med Wochenschr. 1995 Apr 21;120(16):567-70. Review. German. No abstract available.

PMID:
7736947
50.

FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway.

Gulbins E, Bissonnette R, Mahboubi A, Martin S, Nishioka W, Brunner T, Baier G, Baier-Bitterlich G, Byrd C, Lang F, et al.

Immunity. 1995 Apr;2(4):341-51.

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