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Items: 1 to 50 of 105

1.

Rad53- and Chk1-Dependent DNA Damage Response Pathways Cooperatively Promote Fungal Pathogenesis and Modulate Antifungal Drug Susceptibility.

Jung KW, Lee Y, Huh EY, Lee SC, Lim S, Bahn YS.

MBio. 2019 Jan 2;10(1). pii: e01726-18. doi: 10.1128/mBio.01726-18.

2.

Sho1 and Msb2 Play Complementary but Distinct Roles in Stress Responses, Sexual Differentiation, and Pathogenicity of Cryptococcus neoformans.

So YS, Jang J, Park G, Xu J, Olszewski MA, Bahn YS.

Front Microbiol. 2018 Dec 4;9:2958. doi: 10.3389/fmicb.2018.02958. eCollection 2018.

3.

In Vitro and In Vivo Assessment of FK506 Analogs as Novel Antifungal Drug Candidates.

Lee Y, Lee KT, Lee SJ, Beom JY, Hwangbo A, Jung JA, Song MC, Yoo YJ, Kang SH, Averette AF, Heitman J, Yoon YJ, Cheong E, Bahn YS.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01627-18. doi: 10.1128/AAC.01627-18. Print 2018 Nov.

PMID:
30181374
4.

Genetic Manipulation of Cryptococcus neoformans.

Jung KW, Lee KT, So YS, Bahn YS.

Curr Protoc Microbiol. 2018 Aug;50(1):e59. doi: 10.1002/cpmc.59. Epub 2018 Jul 17.

PMID:
30016567
5.

Evolutionarily Conserved and Divergent Roles of Unfolded Protein Response (UPR) in the Pathogenic Cryptococcus Species Complex.

Jung KW, Lee KT, Averette AF, Hoy MJ, Everitt J, Heitman J, Bahn YS.

Sci Rep. 2018 May 25;8(1):8132. doi: 10.1038/s41598-018-26405-5.

6.

The novel microtubule-associated CAP-glycine protein Cgp1 governs growth, differentiation, and virulence of Cryptococcus neoformans.

Wang LL, Lee KT, Jung KW, Lee DG, Bahn YS.

Virulence. 2018 Jan 1;9(1):566-584. doi: 10.1080/21505594.2017.1423189.

7.

Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapy.

Yeon SK, Choi JW, Park JH, Lee YR, Kim HJ, Shin SJ, Jang BK, Kim S, Bahn YS, Han G, Lee YS, Pae AN, Park KD.

Bioorg Med Chem. 2018 Jan 1;26(1):232-244. doi: 10.1016/j.bmc.2017.11.036. Epub 2017 Nov 24.

PMID:
29198609
8.

Crystal structure of inositol 1,3,4,5,6-pentakisphosphate 2-kinase from Cryptococcus neoformans.

Oh J, Lee DG, Bahn YS, Rhee S.

J Struct Biol. 2017 Nov;200(2):118-123. doi: 10.1016/j.jsb.2017.09.004. Epub 2017 Sep 15.

PMID:
28919350
9.

Glucosamine stimulates pheromone-independent dimorphic transition in Cryptococcus neoformans by promoting Crz1 nuclear translocation.

Xu X, Lin J, Zhao Y, Kirkman E, So YS, Bahn YS, Lin X.

PLoS Genet. 2017 Sep 12;13(9):e1006982. doi: 10.1371/journal.pgen.1006982. eCollection 2017 Sep.

10.

Microbial radiation-resistance mechanisms.

Jung KW, Lim S, Bahn YS.

J Microbiol. 2017 Jul;55(7):499-507. doi: 10.1007/s12275-017-7242-5. Epub 2017 Jun 30. Review.

PMID:
28664512
11.

A novel bZIP protein, Gsb1, is required for oxidative stress response, mating, and virulence in the human pathogen Cryptococcus neoformans.

Cheon SA, Thak EJ, Bahn YS, Kang HA.

Sci Rep. 2017 Jun 22;7(1):4044. doi: 10.1038/s41598-017-04290-8.

12.

The water channel protein aquaporin 1 regulates cellular metabolism and competitive fitness in a global fungal pathogen Cryptococcus neoformans.

Meyers GL, Jung KW, Bang S, Kim J, Kim S, Hong J, Cheong E, Kim KH, Bahn YS.

Environ Microbiol Rep. 2017 Jun;9(3):268-278. doi: 10.1111/1758-2229.12527. Epub 2017 Mar 21.

PMID:
28251810
13.

Pho4 Is Essential for Dissemination of Cryptococcus neoformans to the Host Brain by Promoting Phosphate Uptake and Growth at Alkaline pH.

Lev S, Kaufman-Francis K, Desmarini D, Juillard PG, Li C, Stifter SA, Feng CG, Sorrell TC, Grau GE, Bahn YS, Djordjevic JT.

mSphere. 2017 Jan 25;2(1). pii: e00381-16. doi: 10.1128/mSphere.00381-16. eCollection 2017 Jan-Feb.

14.

Unraveling Fungal Radiation Resistance Regulatory Networks through the Genome-Wide Transcriptome and Genetic Analyses of Cryptococcus neoformans.

Jung KW, Yang DH, Kim MK, Seo HS, Lim S, Bahn YS.

MBio. 2016 Nov 29;7(6). pii: e01483-16. doi: 10.1128/mBio.01483-16.

15.

Rewiring of Signaling Networks Modulating Thermotolerance in the Human Pathogen Cryptococcus neoformans.

Yang DH, Jung KW, Bang S, Lee JW, Song MH, Floyd-Averette A, Festa RA, Ianiri G, Idnurm A, Thiele DJ, Heitman J, Bahn YS.

Genetics. 2017 Jan;205(1):201-219. doi: 10.1534/genetics.116.190595. Epub 2016 Nov 18.

16.

Systemic Approach to Virulence Gene Network Analysis for Gaining New Insight into Cryptococcal Virulence.

Malachowski AN, Yosri M, Park G, Bahn YS, He Y, Olszewski MA.

Front Microbiol. 2016 Oct 27;7:1652. eCollection 2016.

17.

Molecular Characterization of Adenylyl Cyclase Complex Proteins Using Versatile Protein-Tagging Plasmid Systems in Cryptococcus neoformans.

So YS, Yang DH, Jung KW, Huh WK, Bahn YS.

J Microbiol Biotechnol. 2017 Feb 28;27(2):357-364. doi: 10.4014/jmb.1609.09036.

18.

Metal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and Morphogenesis.

Polvi EJ, Averette AF, Lee SC, Kim T, Bahn YS, Veri AO, Robbins N, Heitman J, Cowen LE.

PLoS Genet. 2016 Oct 3;12(10):e1006350. doi: 10.1371/journal.pgen.1006350. eCollection 2016 Oct.

19.

Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans.

Lee KT, So YS, Yang DH, Jung KW, Choi J, Lee DG, Kwon H, Jang J, Wang LL, Cha S, Meyers GL, Jeong E, Jin JH, Lee Y, Hong J, Bang S, Ji JH, Park G, Byun HJ, Park SW, Park YM, Adedoyin G, Kim T, Averette AF, Choi JS, Heitman J, Cheong E, Lee YH, Bahn YS.

Nat Commun. 2016 Sep 28;7:12766. doi: 10.1038/ncomms12766.

20.

Age-associated repression of type 1 inositol 1, 4, 5-triphosphate receptor impairs muscle regeneration.

Choi JY, Hwang CY, Lee B, Lee SM, Bahn YJ, Lee KP, Kang M, Kim YS, Woo SH, Lim JY, Kim E, Kwon KS.

Aging (Albany NY). 2016 Sep 21;8(9):2062-2080. doi: 10.18632/aging.101039.

21.

Unique roles of the unfolded protein response pathway in fungal development and differentiation.

Jung KW, So YS, Bahn YS.

Sci Rep. 2016 Sep 15;6:33413. doi: 10.1038/srep33413.

22.

Intron retention-dependent gene regulation in Cryptococcus neoformans.

Gonzalez-Hilarion S, Paulet D, Lee KT, Hon CC, Lechat P, Mogensen E, Moyrand F, Proux C, Barboux R, Bussotti G, Hwang J, Coppée JY, Bahn YS, Janbon G.

Sci Rep. 2016 Aug 31;6:32252. doi: 10.1038/srep32252.

23.

Fungal physiology: Red light plugs into MAPK pathway.

Idnurm A, Bahn YS.

Nat Microbiol. 2016 Apr 26;1:16052. doi: 10.1038/nmicrobiol.2016.52. No abstract available.

PMID:
27572650
24.

Dual action antifungal small molecule modulates multidrug efflux and TOR signaling.

Shekhar-Guturja T, Gunaherath GM, Wijeratne EM, Lambert JP, Averette AF, Lee SC, Kim T, Bahn YS, Tripodi F, Ammar R, Döhl K, Niewola-Staszkowska K, Schmitt L, Loewith RJ, Roth FP, Sanglard D, Andes D, Nislow C, Coccetti P, Gingras AC, Heitman J, Gunatilaka AA, Cowen LE.

Nat Chem Biol. 2016 Oct;12(10):867-75. doi: 10.1038/nchembio.2165. Epub 2016 Aug 29.

25.

Major Sensing Proteins in Pathogenic Fungi: The Hybrid Histidine Kinase Family.

Hérivaux A, So YS, Gastebois A, Latgé JP, Bouchara JP, Bahn YS, Papon N.

PLoS Pathog. 2016 Jul 28;12(7):e1005683. doi: 10.1371/journal.ppat.1005683. eCollection 2016 Jul. Review. No abstract available.

26.

Relative Contributions of Prenylation and Postprenylation Processing in Cryptococcus neoformans Pathogenesis.

Esher SK, Ost KS, Kozubowski L, Yang DH, Kim MS, Bahn YS, Alspaugh JA, Nichols CB.

mSphere. 2016 Mar 30;1(2). pii: e00084-15. doi: 10.1128/mSphere.00084-15. eCollection 2016 Mar-Apr.

27.

Screening, Synthesis, and In Vitro Evaluation of Vinyl Sulfones as Inhibitors of Complement-Dependent Cytotoxicity in Neuromyelitis Optica.

Ju EJ, Yeon SK, Park JH, Cheon SY, Choi JW, Ha T, Jang BK, Kim S, Kang YG, Hwang H, Cho SJ, Cheong E, Bahn YS, Pae AN, Kim SM, Park KD.

ChemMedChem. 2016 Feb 17;11(4):377-81. doi: 10.1002/cmdc.201500546. Epub 2016 Jan 25.

PMID:
26804736
28.

Detection of Urothelial Carcinoma: Comparison of Reduced-Dose Iterative Reconstruction with Standard-Dose Filtered Back Projection.

Bahn YE, Kim SH, Kim MJ, Kim CS, Kim YH, Cho SH.

Radiology. 2016 May;279(2):471-80. doi: 10.1148/radiol.2015150257. Epub 2015 Nov 13.

PMID:
26566141
29.

An Antifungal Combination Matrix Identifies a Rich Pool of Adjuvant Molecules that Enhance Drug Activity against Diverse Fungal Pathogens.

Robbins N, Spitzer M, Yu T, Cerone RP, Averette AK, Bahn YS, Heitman J, Sheppard DC, Tyers M, Wright GD.

Cell Rep. 2015 Nov 17;13(7):1481-1492. doi: 10.1016/j.celrep.2015.10.018. Epub 2015 Nov 5.

30.

miR-431 promotes differentiation and regeneration of old skeletal muscle by targeting Smad4.

Lee KP, Shin YJ, Panda AC, Abdelmohsen K, Kim JY, Lee SM, Bahn YJ, Choi JY, Kwon ES, Baek SJ, Kim SY, Gorospe M, Kwon KS.

Genes Dev. 2015 Aug 1;29(15):1605-17. doi: 10.1101/gad.263574.115. Epub 2015 Jul 27.

31.

Quantification of tricuspid regurgitation using two-dimensional velocity encoding cine: optimal plane and reproducibility.

Jun H, Park EA, Bahn YE, Lee W, Kim HK, Chung JW.

Int J Cardiovasc Imaging. 2015 Dec;31 Suppl 2:233-40. doi: 10.1007/s10554-015-0715-x. Epub 2015 Jul 25.

PMID:
26208682
32.

Exploiting Fungal Virulence-Regulating Transcription Factors As Novel Antifungal Drug Targets.

Bahn YS.

PLoS Pathog. 2015 Jul 16;11(7):e1004936. doi: 10.1371/journal.ppat.1004936. eCollection 2015 Jul. Review. No abstract available.

33.

A Phenylpropanoid Glycoside as a Calcineurin Inhibitor Isolated from Magnolia obovata Thunb.

Lee WJ, Moon JS, Kim SI, Bahn YS, Lee H, Kang TH, Shin HM, Kim SU.

J Microbiol Biotechnol. 2015 Sep;25(9):1429-32. doi: 10.4014/jmb.1506.06031.

34.

Incidence of idiopathic pulmonary fibrosis in Korea based on the 2011 ATS/ERS/JRS/ALAT statement.

Gjonbrataj J, Choi WI, Bahn YE, Rho BH, Lee JJ, Lee CW.

Int J Tuberc Lung Dis. 2015 Jun;19(6):742-6. doi: 10.5588/ijtld.14.0650.

PMID:
25946370
35.

Systematic functional profiling of transcription factor networks in Cryptococcus neoformans.

Jung KW, Yang DH, Maeng S, Lee KT, So YS, Hong J, Choi J, Byun HJ, Kim H, Bang S, Song MH, Lee JW, Kim MS, Kim SY, Ji JH, Park G, Kwon H, Cha S, Meyers GL, Wang LL, Jang J, Janbon G, Adedoyin G, Kim T, Averette AK, Heitman J, Cheong E, Lee YH, Lee YW, Bahn YS.

Nat Commun. 2015 Apr 7;6:6757. doi: 10.1038/ncomms7757.

36.

Digital tomosynthesis for evaluating metastatic lung nodules: nodule visibility, learning curves, and reading times.

Lee KH, Goo JM, Lee SM, Park CM, Bahn YE, Kim H, Song YS, Hwang EJ.

Korean J Radiol. 2015 Mar-Apr;16(2):430-9. doi: 10.3348/kjr.2015.16.2.430. Epub 2015 Feb 27.

37.

Network-assisted genetic dissection of pathogenicity and drug resistance in the opportunistic human pathogenic fungus Cryptococcus neoformans.

Kim H, Jung KW, Maeng S, Chen YL, Shin J, Shim JE, Hwang S, Janbon G, Kim T, Heitman J, Bahn YS, Lee I.

Sci Rep. 2015 Mar 5;5:8767. doi: 10.1038/srep08767.

38.

Clinical findings and outcomes in patients with possible usual interstitial pneumonia.

Lee JW, Shehu E, Gjonbrataj J, Bahn YE, Rho BH, Lee MY, Choi WI.

Respir Med. 2015 Apr;109(4):510-6. doi: 10.1016/j.rmed.2015.02.008. Epub 2015 Feb 14.

39.

Nucleoredoxin promotes adipogenic differentiation through regulation of Wnt/β-catenin signaling.

Bahn YJ, Lee KP, Lee SM, Choi JY, Seo YS, Kwon KS.

J Lipid Res. 2015 Feb;56(2):294-303. doi: 10.1194/jlr.M054056. Epub 2014 Dec 29.

40.

Unraveling the novel structure and biosynthetic pathway of O-linked glycans in the Golgi apparatus of the human pathogenic yeast Cryptococcus neoformans.

Lee DJ, Bahn YS, Kim HJ, Chung SY, Kang HA.

J Biol Chem. 2015 Jan 16;290(3):1861-73. doi: 10.1074/jbc.M114.607705. Epub 2014 Dec 4.

41.

9-O-butyl-13-(4-isopropylbenzyl)berberine, KR-72, is a potent antifungal agent that inhibits the growth of Cryptococcus neoformans by regulating gene expression.

Bang S, Kwon H, Hwang HS, Park KD, Kim SU, Bahn YS.

PLoS One. 2014 Oct 10;9(10):e109863. doi: 10.1371/journal.pone.0109863. eCollection 2014.

42.

Peroxiredoxin 3 has a crucial role in the contractile function of skeletal muscle by regulating mitochondrial homeostasis.

Lee KP, Shin YJ, Cho SC, Lee SM, Bahn YJ, Kim JY, Kwon ES, Jeong DY, Park SC, Rhee SG, Woo HA, Kwon KS.

Free Radic Biol Med. 2014 Dec;77:298-306. doi: 10.1016/j.freeradbiomed.2014.09.010. Epub 2014 Sep 16.

PMID:
25224038
43.

A Ferroxidase, Cfo1, Regulates Diverse Environmental Stress Responses of Cryptococcus neoformans through the HOG Pathway.

Lee KT, Lee JW, Lee D, Jung WH, Bahn YS.

Mycobiology. 2014 Jun;42(2):152-7. doi: 10.5941/MYCO.2014.42.2.152. Epub 2014 Jun 30.

44.

Inhibition of the calcineurin pathway by two tannins, chebulagic acid and chebulanin, isolated from Harrisonia abyssinica Oliv.

Lee WJ, Moon JS, Kim SI, Kim YT, Nash O, Bahn YS, Kim SU.

J Microbiol Biotechnol. 2014 Oct;24(10):1377-81.

45.

Cryptococcus neoformans and Cryptococcus gattii, the etiologic agents of cryptococcosis.

Kwon-Chung KJ, Fraser JA, Doering TL, Wang Z, Janbon G, Idnurm A, Bahn YS.

Cold Spring Harb Perspect Med. 2014 Jul 1;4(7):a019760. doi: 10.1101/cshperspect.a019760. Review.

46.

A Nudix Hydrolase Protein, Ysa1, Regulates Oxidative Stress Response and Antifungal Drug Susceptibility in Cryptococcus neoformans.

Lee KT, Kwon H, Lee D, Bahn YS.

Mycobiology. 2014 Mar;42(1):52-8. doi: 10.5941/MYCO.2014.42.1.52. Epub 2014 Mar 31.

47.

Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation.

Janbon G, Ormerod KL, Paulet D, Byrnes EJ 3rd, Yadav V, Chatterjee G, Mullapudi N, Hon CC, Billmyre RB, Brunel F, Bahn YS, Chen W, Chen Y, Chow EW, Coppée JY, Floyd-Averette A, Gaillardin C, Gerik KJ, Goldberg J, Gonzalez-Hilarion S, Gujja S, Hamlin JL, Hsueh YP, Ianiri G, Jones S, Kodira CD, Kozubowski L, Lam W, Marra M, Mesner LD, Mieczkowski PA, Moyrand F, Nielsen K, Proux C, Rossignol T, Schein JE, Sun S, Wollschlaeger C, Wood IA, Zeng Q, Neuvéglise C, Newlon CS, Perfect JR, Lodge JK, Idnurm A, Stajich JE, Kronstad JW, Sanyal K, Heitman J, Fraser JA, Cuomo CA, Dietrich FS.

PLoS Genet. 2014 Apr 17;10(4):e1004261. doi: 10.1371/journal.pgen.1004261. eCollection 2014 Apr.

48.

Distinct and redundant roles of protein tyrosine phosphatases Ptp1 and Ptp2 in governing the differentiation and pathogenicity of Cryptococcus neoformans.

Lee KT, Byun HJ, Jung KW, Hong J, Cheong E, Bahn YS.

Eukaryot Cell. 2014 Jun;13(6):796-812. doi: 10.1128/EC.00069-14. Epub 2014 Apr 11.

49.

The management of traumatic scalp pseudoaneurysms with manual or US-guided compression.

Lee EJ, Kim JH, Chang HW, Bahn YE, Kim E, Kim SP, Sohn SI, Cho YW, Lee H.

Br J Neurosurg. 2014 Jun;28(3):418-20. doi: 10.3109/02688697.2014.889808. Epub 2014 Feb 19.

PMID:
24552258
50.

The unfolded protein response (UPR) pathway in Cryptococcus.

Cheon SA, Jung KW, Bahn YS, Kang HA.

Virulence. 2014 Feb 15;5(2):341-50. doi: 10.4161/viru.26774. Epub 2013 Oct 18. Review.

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