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Items: 1 to 50 of 115


Protection from β-cell apoptosis by inhibition of TGF-β/Smad3 signaling.

Lee JH, Mellado-Gil JM, Bahn YJ, Pathy SM, Zhang YE, Rane SG.

Cell Death Dis. 2020 Mar 13;11(3):184. doi: 10.1038/s41419-020-2365-8.


Antioxidant Activities of an Exopolysaccharide (DeinoPol) Produced by the Extreme Radiation-Resistant Bacterium Deinococcus radiodurans.

Lin SM, Baek CY, Jung JH, Kim WS, Song HY, Lee JH, Ji HJ, Zhi Y, Kang BS, Bahn YS, Seo HS, Lim S.

Sci Rep. 2020 Jan 9;10(1):55. doi: 10.1038/s41598-019-56141-3.


Corrigendum to: Molecular Characterization of Adenylyl Cyclase Complex Proteins Using Versatile Protein-Tagging Plasmid Systems in Cryptococcus neoformans.

So YS, Yang DH, Jung KW, Huh WK, Bahn YS.

J Microbiol Biotechnol. 2019 Dec 28;29(12):2026. doi: 10.4014/jmb.2019.2912.2026.


Regulatory Mechanism of the Atypical AP-1-Like Transcription Factor Yap1 in Cryptococcus neoformans.

So YS, Maeng S, Yang DH, Kim H, Lee KT, Yu SR, Tenor JL, Giri VK, Toffaletti DL, Arras S, Fraser JA, Perfect JR, Bahn YS.

mSphere. 2019 Nov 20;4(6). pii: e00785-19. doi: 10.1128/mSphere.00785-19.


Structural analysis of fungal pathogenicity-related casein kinase α subunit, Cka1, in the human fungal pathogen Cryptococcus neoformans.

Ong BX, Yoo Y, Han MG, Park JB, Choi MK, Choi Y, Shin JS, Bahn YS, Cho HS.

Sci Rep. 2019 Oct 7;9(1):14398. doi: 10.1038/s41598-019-50678-z.


Unraveling Melanin Biosynthesis and Signaling Networks in Cryptococcus neoformans.

Lee D, Jang EH, Lee M, Kim SW, Lee Y, Lee KT, Bahn YS.

mBio. 2019 Oct 1;10(5). pii: e02267-19. doi: 10.1128/mBio.02267-19.


Biosynthesis of Nonimmunosuppressive FK506 Analogues with Antifungal Activity.

Beom JY, Jung JA, Lee KT, Hwangbo A, Song MC, Lee Y, Lee SJ, Oh JH, Ha SJ, Nam SJ, Cheong E, Bahn YS, Yoon YJ.

J Nat Prod. 2019 Aug 23;82(8):2078-2086. doi: 10.1021/acs.jnatprod.9b00144. Epub 2019 Jul 19.


Antioxidant, Anti-inflammatory, and Neuroprotective Effects of Novel Vinyl Sulfonate Compounds as Nrf2 Activator.

Choi JW, Shin SJ, Kim HJ, Park JH, Kim HJ, Lee EH, Pae AN, Bahn YS, Park KD.

ACS Med Chem Lett. 2019 Jun 3;10(7):1061-1067. doi: 10.1021/acsmedchemlett.9b00163. eCollection 2019 Jul 11.


The TOR Pathway Plays Pleiotropic Roles in Growth and Stress Responses of the Fungal Pathogen Cryptococcus neoformans.

So YS, Lee DG, Idnurm A, Ianiri G, Bahn YS.

Genetics. 2019 Aug;212(4):1241-1258. doi: 10.1534/genetics.119.302191. Epub 2019 Jun 7.


Nutrient and Stress Sensing in Pathogenic Yeasts.

Rutherford JC, Bahn YS, van den Berg B, Heitman J, Xue C.

Front Microbiol. 2019 Mar 8;10:442. doi: 10.3389/fmicb.2019.00442. eCollection 2019. Review.


Rad53- and Chk1-Dependent DNA Damage Response Pathways Cooperatively Promote Fungal Pathogenesis and Modulate Antifungal Drug Susceptibility.

Jung KW, Lee Y, Huh EY, Lee SC, Lim S, Bahn YS.

mBio. 2019 Jan 2;10(1). pii: e01726-18. doi: 10.1128/mBio.01726-18.


Sho1 and Msb2 Play Complementary but Distinct Roles in Stress Responses, Sexual Differentiation, and Pathogenicity of Cryptococcus neoformans.

So YS, Jang J, Park G, Xu J, Olszewski MA, Bahn YS.

Front Microbiol. 2018 Dec 4;9:2958. doi: 10.3389/fmicb.2018.02958. eCollection 2018.


In Vitro and In Vivo Assessment of FK506 Analogs as Novel Antifungal Drug Candidates.

Lee Y, Lee KT, Lee SJ, Beom JY, Hwangbo A, Jung JA, Song MC, Yoo YJ, Kang SH, Averette AF, Heitman J, Yoon YJ, Cheong E, Bahn YS.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01627-18. doi: 10.1128/AAC.01627-18. Print 2018 Nov.


Genetic Manipulation of Cryptococcus neoformans.

Jung KW, Lee KT, So YS, Bahn YS.

Curr Protoc Microbiol. 2018 Aug;50(1):e59. doi: 10.1002/cpmc.59. Epub 2018 Jul 17.


Evolutionarily Conserved and Divergent Roles of Unfolded Protein Response (UPR) in the Pathogenic Cryptococcus Species Complex.

Jung KW, Lee KT, Averette AF, Hoy MJ, Everitt J, Heitman J, Bahn YS.

Sci Rep. 2018 May 25;8(1):8132. doi: 10.1038/s41598-018-26405-5.


The novel microtubule-associated CAP-glycine protein Cgp1 governs growth, differentiation, and virulence of Cryptococcus neoformans.

Wang LL, Lee KT, Jung KW, Lee DG, Bahn YS.

Virulence. 2018 Jan 1;9(1):566-584. doi: 10.1080/21505594.2017.1423189.


Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapy.

Yeon SK, Choi JW, Park JH, Lee YR, Kim HJ, Shin SJ, Jang BK, Kim S, Bahn YS, Han G, Lee YS, Pae AN, Park KD.

Bioorg Med Chem. 2018 Jan 1;26(1):232-244. doi: 10.1016/j.bmc.2017.11.036. Epub 2017 Nov 24.


Crystal structure of inositol 1,3,4,5,6-pentakisphosphate 2-kinase from Cryptococcus neoformans.

Oh J, Lee DG, Bahn YS, Rhee S.

J Struct Biol. 2017 Nov;200(2):118-123. doi: 10.1016/j.jsb.2017.09.004. Epub 2017 Sep 15.


Glucosamine stimulates pheromone-independent dimorphic transition in Cryptococcus neoformans by promoting Crz1 nuclear translocation.

Xu X, Lin J, Zhao Y, Kirkman E, So YS, Bahn YS, Lin X.

PLoS Genet. 2017 Sep 12;13(9):e1006982. doi: 10.1371/journal.pgen.1006982. eCollection 2017 Sep.


Microbial radiation-resistance mechanisms.

Jung KW, Lim S, Bahn YS.

J Microbiol. 2017 Jul;55(7):499-507. doi: 10.1007/s12275-017-7242-5. Epub 2017 Jun 30. Review.


A novel bZIP protein, Gsb1, is required for oxidative stress response, mating, and virulence in the human pathogen Cryptococcus neoformans.

Cheon SA, Thak EJ, Bahn YS, Kang HA.

Sci Rep. 2017 Jun 22;7(1):4044. doi: 10.1038/s41598-017-04290-8.


The water channel protein aquaporin 1 regulates cellular metabolism and competitive fitness in a global fungal pathogen Cryptococcus neoformans.

Meyers GL, Jung KW, Bang S, Kim J, Kim S, Hong J, Cheong E, Kim KH, Bahn YS.

Environ Microbiol Rep. 2017 Jun;9(3):268-278. doi: 10.1111/1758-2229.12527. Epub 2017 Mar 21.


Pho4 Is Essential for Dissemination of Cryptococcus neoformans to the Host Brain by Promoting Phosphate Uptake and Growth at Alkaline pH.

Lev S, Kaufman-Francis K, Desmarini D, Juillard PG, Li C, Stifter SA, Feng CG, Sorrell TC, Grau GE, Bahn YS, Djordjevic JT.

mSphere. 2017 Jan 25;2(1). pii: e00381-16. doi: 10.1128/mSphere.00381-16. eCollection 2017 Jan-Feb.


Unraveling Fungal Radiation Resistance Regulatory Networks through the Genome-Wide Transcriptome and Genetic Analyses of Cryptococcus neoformans.

Jung KW, Yang DH, Kim MK, Seo HS, Lim S, Bahn YS.

mBio. 2016 Nov 29;7(6). pii: e01483-16. doi: 10.1128/mBio.01483-16.


Rewiring of Signaling Networks Modulating Thermotolerance in the Human Pathogen Cryptococcus neoformans.

Yang DH, Jung KW, Bang S, Lee JW, Song MH, Floyd-Averette A, Festa RA, Ianiri G, Idnurm A, Thiele DJ, Heitman J, Bahn YS.

Genetics. 2017 Jan;205(1):201-219. doi: 10.1534/genetics.116.190595. Epub 2016 Nov 18.


Systemic Approach to Virulence Gene Network Analysis for Gaining New Insight into Cryptococcal Virulence.

Malachowski AN, Yosri M, Park G, Bahn YS, He Y, Olszewski MA.

Front Microbiol. 2016 Oct 27;7:1652. eCollection 2016.


Molecular Characterization of Adenylyl Cyclase Complex Proteins Using Versatile Protein-Tagging Plasmid Systems in Cryptococcus neoformans.

So YS, Yang DH, Jung KW, Huh WK, Bahn YS.

J Microbiol Biotechnol. 2017 Feb 28;27(2):357-364. doi: 10.4014/jmb.1609.09036. Erratum in: J Microbiol Biotechnol. 2019 Dec 28;29(12):2026.


Metal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and Morphogenesis.

Polvi EJ, Averette AF, Lee SC, Kim T, Bahn YS, Veri AO, Robbins N, Heitman J, Cowen LE.

PLoS Genet. 2016 Oct 3;12(10):e1006350. doi: 10.1371/journal.pgen.1006350. eCollection 2016 Oct.


Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans.

Lee KT, So YS, Yang DH, Jung KW, Choi J, Lee DG, Kwon H, Jang J, Wang LL, Cha S, Meyers GL, Jeong E, Jin JH, Lee Y, Hong J, Bang S, Ji JH, Park G, Byun HJ, Park SW, Park YM, Adedoyin G, Kim T, Averette AF, Choi JS, Heitman J, Cheong E, Lee YH, Bahn YS.

Nat Commun. 2016 Sep 28;7:12766. doi: 10.1038/ncomms12766.


Age-associated repression of type 1 inositol 1, 4, 5-triphosphate receptor impairs muscle regeneration.

Choi JY, Hwang CY, Lee B, Lee SM, Bahn YJ, Lee KP, Kang M, Kim YS, Woo SH, Lim JY, Kim E, Kwon KS.

Aging (Albany NY). 2016 Sep 21;8(9):2062-2080. doi: 10.18632/aging.101039.


Unique roles of the unfolded protein response pathway in fungal development and differentiation.

Jung KW, So YS, Bahn YS.

Sci Rep. 2016 Sep 15;6:33413. doi: 10.1038/srep33413.


Intron retention-dependent gene regulation in Cryptococcus neoformans.

Gonzalez-Hilarion S, Paulet D, Lee KT, Hon CC, Lechat P, Mogensen E, Moyrand F, Proux C, Barboux R, Bussotti G, Hwang J, Coppée JY, Bahn YS, Janbon G.

Sci Rep. 2016 Aug 31;6:32252. doi: 10.1038/srep32252.


Fungal physiology: Red light plugs into MAPK pathway.

Idnurm A, Bahn YS.

Nat Microbiol. 2016 Apr 26;1:16052. doi: 10.1038/nmicrobiol.2016.52. No abstract available.


Dual action antifungal small molecule modulates multidrug efflux and TOR signaling.

Shekhar-Guturja T, Gunaherath GM, Wijeratne EM, Lambert JP, Averette AF, Lee SC, Kim T, Bahn YS, Tripodi F, Ammar R, Döhl K, Niewola-Staszkowska K, Schmitt L, Loewith RJ, Roth FP, Sanglard D, Andes D, Nislow C, Coccetti P, Gingras AC, Heitman J, Gunatilaka AA, Cowen LE.

Nat Chem Biol. 2016 Oct;12(10):867-75. doi: 10.1038/nchembio.2165. Epub 2016 Aug 29.


Major Sensing Proteins in Pathogenic Fungi: The Hybrid Histidine Kinase Family.

Hérivaux A, So YS, Gastebois A, Latgé JP, Bouchara JP, Bahn YS, Papon N.

PLoS Pathog. 2016 Jul 28;12(7):e1005683. doi: 10.1371/journal.ppat.1005683. eCollection 2016 Jul. Review. No abstract available.


Relative Contributions of Prenylation and Postprenylation Processing in Cryptococcus neoformans Pathogenesis.

Esher SK, Ost KS, Kozubowski L, Yang DH, Kim MS, Bahn YS, Alspaugh JA, Nichols CB.

mSphere. 2016 Mar 30;1(2). pii: e00084-15. doi: 10.1128/mSphere.00084-15. eCollection 2016 Mar-Apr.


Screening, Synthesis, and In Vitro Evaluation of Vinyl Sulfones as Inhibitors of Complement-Dependent Cytotoxicity in Neuromyelitis Optica.

Ju EJ, Yeon SK, Park JH, Cheon SY, Choi JW, Ha T, Jang BK, Kim S, Kang YG, Hwang H, Cho SJ, Cheong E, Bahn YS, Pae AN, Kim SM, Park KD.

ChemMedChem. 2016 Feb 17;11(4):377-81. doi: 10.1002/cmdc.201500546. Epub 2016 Jan 25.


Detection of Urothelial Carcinoma: Comparison of Reduced-Dose Iterative Reconstruction with Standard-Dose Filtered Back Projection.

Bahn YE, Kim SH, Kim MJ, Kim CS, Kim YH, Cho SH.

Radiology. 2016 May;279(2):471-80. doi: 10.1148/radiol.2015150257. Epub 2015 Nov 13.


An Antifungal Combination Matrix Identifies a Rich Pool of Adjuvant Molecules that Enhance Drug Activity against Diverse Fungal Pathogens.

Robbins N, Spitzer M, Yu T, Cerone RP, Averette AK, Bahn YS, Heitman J, Sheppard DC, Tyers M, Wright GD.

Cell Rep. 2015 Nov 17;13(7):1481-1492. doi: 10.1016/j.celrep.2015.10.018. Epub 2015 Nov 5.


miR-431 promotes differentiation and regeneration of old skeletal muscle by targeting Smad4.

Lee KP, Shin YJ, Panda AC, Abdelmohsen K, Kim JY, Lee SM, Bahn YJ, Choi JY, Kwon ES, Baek SJ, Kim SY, Gorospe M, Kwon KS.

Genes Dev. 2015 Aug 1;29(15):1605-17. doi: 10.1101/gad.263574.115. Epub 2015 Jul 27.


Quantification of tricuspid regurgitation using two-dimensional velocity encoding cine: optimal plane and reproducibility.

Jun H, Park EA, Bahn YE, Lee W, Kim HK, Chung JW.

Int J Cardiovasc Imaging. 2015 Dec;31 Suppl 2:233-40. doi: 10.1007/s10554-015-0715-x. Epub 2015 Jul 25.


Exploiting Fungal Virulence-Regulating Transcription Factors As Novel Antifungal Drug Targets.

Bahn YS.

PLoS Pathog. 2015 Jul 16;11(7):e1004936. doi: 10.1371/journal.ppat.1004936. eCollection 2015 Jul. Review. No abstract available.


A Phenylpropanoid Glycoside as a Calcineurin Inhibitor Isolated from Magnolia obovata Thunb.

Lee WJ, Moon JS, Kim SI, Bahn YS, Lee H, Kang TH, Shin HM, Kim SU.

J Microbiol Biotechnol. 2015 Sep;25(9):1429-32. doi: 10.4014/jmb.1506.06031.


Incidence of idiopathic pulmonary fibrosis in Korea based on the 2011 ATS/ERS/JRS/ALAT statement.

Gjonbrataj J, Choi WI, Bahn YE, Rho BH, Lee JJ, Lee CW.

Int J Tuberc Lung Dis. 2015 Jun;19(6):742-6. doi: 10.5588/ijtld.14.0650.


Systematic functional profiling of transcription factor networks in Cryptococcus neoformans.

Jung KW, Yang DH, Maeng S, Lee KT, So YS, Hong J, Choi J, Byun HJ, Kim H, Bang S, Song MH, Lee JW, Kim MS, Kim SY, Ji JH, Park G, Kwon H, Cha S, Meyers GL, Wang LL, Jang J, Janbon G, Adedoyin G, Kim T, Averette AK, Heitman J, Cheong E, Lee YH, Lee YW, Bahn YS.

Nat Commun. 2015 Apr 7;6:6757. doi: 10.1038/ncomms7757.


Digital tomosynthesis for evaluating metastatic lung nodules: nodule visibility, learning curves, and reading times.

Lee KH, Goo JM, Lee SM, Park CM, Bahn YE, Kim H, Song YS, Hwang EJ.

Korean J Radiol. 2015 Mar-Apr;16(2):430-9. doi: 10.3348/kjr.2015.16.2.430. Epub 2015 Feb 27.


Network-assisted genetic dissection of pathogenicity and drug resistance in the opportunistic human pathogenic fungus Cryptococcus neoformans.

Kim H, Jung KW, Maeng S, Chen YL, Shin J, Shim JE, Hwang S, Janbon G, Kim T, Heitman J, Bahn YS, Lee I.

Sci Rep. 2015 Mar 5;5:8767. doi: 10.1038/srep08767.


Clinical findings and outcomes in patients with possible usual interstitial pneumonia.

Lee JW, Shehu E, Gjonbrataj J, Bahn YE, Rho BH, Lee MY, Choi WI.

Respir Med. 2015 Apr;109(4):510-6. doi: 10.1016/j.rmed.2015.02.008. Epub 2015 Feb 14.


Nucleoredoxin promotes adipogenic differentiation through regulation of Wnt/β-catenin signaling.

Bahn YJ, Lee KP, Lee SM, Choi JY, Seo YS, Kwon KS.

J Lipid Res. 2015 Feb;56(2):294-303. doi: 10.1194/jlr.M054056. Epub 2014 Dec 29.


Unraveling the novel structure and biosynthetic pathway of O-linked glycans in the Golgi apparatus of the human pathogenic yeast Cryptococcus neoformans.

Lee DJ, Bahn YS, Kim HJ, Chung SY, Kang HA.

J Biol Chem. 2015 Jan 16;290(3):1861-73. doi: 10.1074/jbc.M114.607705. Epub 2014 Dec 4.

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