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Items: 22

1.

Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers.

Sulahian R, Kwon JJ, Walsh KH, Pailler E, Bosse TL, Thaker M, Almanza D, Dempster JM, Pan J, Piccioni F, Dumont N, Gonzalez A, Rennhack J, Nabet B, Bachman JA, Goodale A, Lee Y, Bagul M, Liao R, Navarro A, Yuan TL, Ng RWS, Raghavan S, Gray NS, Tsherniak A, Vazquez F, Root DE, Firestone AJ, Settleman J, Hahn WC, Aguirre AJ.

Cell Rep. 2019 Oct 1;29(1):118-134.e8. doi: 10.1016/j.celrep.2019.08.090.

2.

Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer.

Stover EH, Baco MB, Cohen O, Li YY, Christie EL, Bagul M, Goodale A, Lee Y, Pantel S, Rees MG, Wei G, Presser AG, Gelbard MK, Zhang W, Zervantonakis IK, Bhola PD, Ryan J, Guerriero JL, Montero J, Liang FJ, Cherniack AD, Piccioni F, Matulonis UA, Bowtell DDL, Sarosiek KA, Letai A, Garraway LA, Johannessen CM, Meyerson M.

Mol Cancer Res. 2019 Aug 28. doi: 10.1158/1541-7786.MCR-18-1243. [Epub ahead of print]

PMID:
31462500
3.

A Functional Landscape of Resistance to MEK1/2 and CDK4/6 Inhibition in NRAS-Mutant Melanoma.

Hayes TK, Luo F, Cohen O, Goodale AB, Lee Y, Pantel S, Bagul M, Piccioni F, Root DE, Garraway LA, Meyerson M, Johannessen CM.

Cancer Res. 2019 May 1;79(9):2352-2366. doi: 10.1158/0008-5472.CAN-18-2711. Epub 2019 Feb 28.

PMID:
30819666
4.

Enhanced dissolution/caco-2 permeability, pharmacokinetic and pharmacodynamic performance of re-dispersible eprosartan mesylate nanopowder.

Shekhawat P, Bagul M, Edwankar D, Pokharkar V.

Eur J Pharm Sci. 2019 Apr 30;132:72-85. doi: 10.1016/j.ejps.2019.02.021. Epub 2019 Feb 22.

PMID:
30797937
5.

The Canonical Wnt Pathway Drives Macropinocytosis in Cancer.

Redelman-Sidi G, Binyamin A, Gaeta I, Palm W, Thompson CB, Romesser PB, Lowe SW, Bagul M, Doench JG, Root DE, Glickman MS.

Cancer Res. 2018 Aug 15;78(16):4658-4670. doi: 10.1158/0008-5472.CAN-17-3199. Epub 2018 Jun 5.

6.

Bioactive characteristics and optimization of tamarind seed protein hydrolysate for antioxidant-rich food formulations.

Bagul MB, Sonawane SK, Arya SS.

3 Biotech. 2018 Apr;8(4):218. doi: 10.1007/s13205-018-1240-0. Epub 2018 Apr 12.

7.

High-throughput Phenotyping of Lung Cancer Somatic Mutations.

Berger AH, Brooks AN, Wu X, Shrestha Y, Chouinard C, Piccioni F, Bagul M, Kamburov A, Imielinski M, Hogstrom L, Zhu C, Yang X, Pantel S, Sakai R, Watson J, Kaplan N, Campbell JD, Singh S, Root DE, Narayan R, Natoli T, Lahr DL, Tirosh I, Tamayo P, Getz G, Wong B, Doench J, Subramanian A, Golub TR, Meyerson M, Boehm JS.

Cancer Cell. 2017 Dec 11;32(6):884. doi: 10.1016/j.ccell.2017.11.008. No abstract available.

8.

A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.

Subramanian A, Narayan R, Corsello SM, Peck DD, Natoli TE, Lu X, Gould J, Davis JF, Tubelli AA, Asiedu JK, Lahr DL, Hirschman JE, Liu Z, Donahue M, Julian B, Khan M, Wadden D, Smith IC, Lam D, Liberzon A, Toder C, Bagul M, Orzechowski M, Enache OM, Piccioni F, Johnson SA, Lyons NJ, Berger AH, Shamji AF, Brooks AN, Vrcic A, Flynn C, Rosains J, Takeda DY, Hu R, Davison D, Lamb J, Ardlie K, Hogstrom L, Greenside P, Gray NS, Clemons PA, Silver S, Wu X, Zhao WN, Read-Button W, Wu X, Haggarty SJ, Ronco LV, Boehm JS, Schreiber SL, Doench JG, Bittker JA, Root DE, Wong B, Golub TR.

Cell. 2017 Nov 30;171(6):1437-1452.e17. doi: 10.1016/j.cell.2017.10.049.

9.

Phenotypic Characterization of a Comprehensive Set of MAPK1/ERK2 Missense Mutants.

Brenan L, Andreev A, Cohen O, Pantel S, Kamburov A, Cacchiarelli D, Persky NS, Zhu C, Bagul M, Goetz EM, Burgin AB, Garraway LA, Getz G, Mikkelsen TS, Piccioni F, Root DE, Johannessen CM.

Cell Rep. 2016 Oct 18;17(4):1171-1183. doi: 10.1016/j.celrep.2016.09.061.

10.

High-throughput Phenotyping of Lung Cancer Somatic Mutations.

Berger AH, Brooks AN, Wu X, Shrestha Y, Chouinard C, Piccioni F, Bagul M, Kamburov A, Imielinski M, Hogstrom L, Zhu C, Yang X, Pantel S, Sakai R, Watson J, Kaplan N, Campbell JD, Singh S, Root DE, Narayan R, Natoli T, Lahr DL, Tirosh I, Tamayo P, Getz G, Wong B, Doench J, Subramanian A, Golub TR, Meyerson M, Boehm JS.

Cancer Cell. 2016 Aug 8;30(2):214-228. doi: 10.1016/j.ccell.2016.06.022. Epub 2016 Jul 28. Erratum in: Cancer Cell. 2017 Dec 11;32(6):884.

11.

Adjunctive perampanel in adolescents with inadequately controlled partial-onset seizures: A randomized study evaluating behavior, efficacy, and safety.

Lagae L, Villanueva V, Meador KJ, Bagul M, Laurenza A, Kumar D, Yang H.

Epilepsia. 2016 Jul;57(7):1120-9. doi: 10.1111/epi.13417. Epub 2016 May 25.

12.

Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles.

Kim E, Ilic N, Shrestha Y, Zou L, Kamburov A, Zhu C, Yang X, Lubonja R, Tran N, Nguyen C, Lawrence MS, Piccioni F, Bagul M, Doench JG, Chouinard CR, Wu X, Hogstrom L, Natoli T, Tamayo P, Horn H, Corsello SM, Lage K, Root DE, Subramanian A, Golub TR, Getz G, Boehm JS, Hahn WC.

Cancer Discov. 2016 Jul;6(7):714-26. doi: 10.1158/2159-8290.CD-16-0160. Epub 2016 May 4.

13.

Real-world data on eslicarbazepine acetate as add-on to antiepileptic monotherapy.

Holtkamp M, McMurray R, Bagul M, Sousa R, Kockelmann E.

Acta Neurol Scand. 2016 Jul;134(1):76-82. doi: 10.1111/ane.12574. Epub 2016 Feb 24.

14.

Crude Garlic Extract Inhibits Cell Proliferation and Induces Cell Cycle Arrest and Apoptosis of Cancer Cells In Vitro.

Bagul M, Kakumanu S, Wilson TA.

J Med Food. 2015 Jul;18(7):731-7. doi: 10.1089/jmf.2014.0064. Epub 2015 Jan 21.

PMID:
25608085
15.

Genetic modifiers of EGFR dependence in non-small cell lung cancer.

Sharifnia T, Rusu V, Piccioni F, Bagul M, Imielinski M, Cherniack AD, Pedamallu CS, Wong B, Wilson FH, Garraway LA, Altshuler D, Golub TR, Root DE, Subramanian A, Meyerson M.

Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18661-6. doi: 10.1073/pnas.1412228112. Epub 2014 Dec 15.

16.

Long-term safety of perampanel and seizure outcomes in refractory partial-onset seizures and secondarily generalized seizures: results from phase III extension study 307.

Krauss GL, Perucca E, Ben-Menachem E, Kwan P, Shih JJ, Clément JF, Wang X, Bagul M, Gee M, Zhu J, Squillacote D.

Epilepsia. 2014 Jul;55(7):1058-68. doi: 10.1111/epi.12643. Epub 2014 May 27.

17.

A targeted RNA interference screen reveals novel epigenetic factors that regulate herpesviral gene expression.

Oh HS, Bryant KF, Nieland TJ, Mazumder A, Bagul M, Bathe M, Root DE, Knipe DM.

MBio. 2014 Feb 4;5(1):e01086-13. doi: 10.1128/mBio.01086-13.

18.

Development and validation of zero and first-order derivative area under curve spectrophotometric methods for the determination of entacapone in bulk material and in tablets.

Chalikwar SS, Shirkhedkar AA, Bagul MA, Jain PS, Surana SJ.

Pharm Methods. 2012 Jan;3(1):14-7. doi: 10.4103/2229-4708.97709.

19.

Primary ileal mesenteric hydatidosis: A rare cause of colicky abdominal pain in childhood.

Bagul A, Bagul M.

J Paediatr Child Health. 2009 Dec;45(12):769-70. doi: 10.1111/j.1440-1754.2009.01281.x. No abstract available.

PMID:
20416006
20.

Evaluation of free radical scavenging activity of an ayurvedic formulation, panchvalkala.

Anandjiwala S, Bagul MS, Parabia M, Rajani M.

Indian J Pharm Sci. 2008 Jan;70(1):31-5. doi: 10.4103/0250-474X.40328.

21.

Evaluation of free radical scavenging properties of two classical polyherbal formulations.

Bagul MS, Kanaki NS, Rajani M.

Indian J Exp Biol. 2005 Aug;43(8):732-6.

PMID:
16121716
22.

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