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Barriers and facilitators to adopting high value practices and de-adopting low value practices in Canadian intensive care units: a multimethod study.

Sauro K, Bagshaw SM, Niven D, Soo A, Brundin-Mather R, Parsons Leigh J, Cook DJ, Stelfox HT.

BMJ Open. 2019 Mar 15;9(3):e024159. doi: 10.1136/bmjopen-2018-024159.


Association between strained ICU capacity and healthcare costs in Canada: A population-based cohort study.

Tran DT, Thanh NX, Opgenorth D, Wang X, Zuege D, Zygun DA, Stelfox HT, Bagshaw SM.

J Crit Care. 2019 Feb 26;51:175-183. doi: 10.1016/j.jcrc.2019.02.025. [Epub ahead of print]


Relaxation for Critically ill Patient Outcomes and Stress-coping Enhancement (REPOSE): a protocol for a pilot randomised trial of an integrative intervention to improve critically ill patients' delirium and related outcomes.

Papathanassoglou EDE, Skrobik Y, Hegadoren K, Thompson P, Stelfox HT, Norris C, Rose L, Bagshaw SM, Meier M, LoCicero C, Ashmore R, Sparrow Brulotte T, Hassan I, Park T, Kutsogiannis DJ.

BMJ Open. 2019 Jan 15;9(1):e023961. doi: 10.1136/bmjopen-2018-023961.


Brain natriuretic peptide to predict successful liberation from mechanical ventilation in critically ill patients: protocol for a systematic review and meta-analysis.

Deschamps J, Webber J, Featherstone R, Sebastianski M, Vandermeer B, Senaratne J, Bagshaw SM.

BMJ Open. 2019 Feb 12;9(2):e022600. doi: 10.1136/bmjopen-2018-022600.


Atrial natriuretic peptide for treatment of acute kidney injury (AKI) - Initiate an optimal dose early.

Ricksten SE, Bagshaw SM.

J Crit Care. 2018 Dec 26. pii: S0883-9441(18)31778-7. doi: 10.1016/j.jcrc.2018.12.013. [Epub ahead of print] No abstract available.


A multicentre controlled pre-post trial of an implementation science intervention to improve venous thromboembolism prophylaxis in critically ill patients.

Stelfox HT, Brundin-Mather R, Soo A, Parsons Leigh J, Niven DJ, Fiest KM, Doig CJ, Zuege DJ, Kushner B, Clement F, Straus SE, Cook DJ, Bagshaw SM, Sauro KM.

Intensive Care Med. 2019 Feb;45(2):211-222. doi: 10.1007/s00134-019-05532-1. Epub 2019 Feb 1.


Caloric intake and the fat-to-carbohydrate ratio in hypercapnic acute respiratory failure: Post-hoc analysis of the PermiT trial.

Al-Dorzi HM, Aldawood AS, Tamim H, Haddad SH, Jones G, McIntyre L, Solaiman O, Sakhija M, Sadat M, Afesh L, Kumar A, Bagshaw SM, Mehta S, M Arabi Y.

Clin Nutr ESPEN. 2019 Feb;29:175-182. doi: 10.1016/j.clnesp.2018.10.012. Epub 2018 Nov 13.


Comparison of outcomes and costs between adult diabetic ketoacidosis patients admitted to the ICU and step-down unit.

Fernando SM, Bagshaw SM, Rochwerg B, McIsaac DI, Thavorn K, Forster AJ, Tran A, Reardon PM, Rosenberg E, Tanuseputro P, Kyeremanteng K.

J Crit Care. 2019 Apr;50:257-261. doi: 10.1016/j.jcrc.2018.12.014. Epub 2018 Dec 25.


Acute Management of Diabetic Ketoacidosis in Adults at 3 Teaching Hospitals in Canada: A Multicentre, Retrospective Cohort Study.

Galm BP, Bagshaw SM, Senior PA.

Can J Diabetes. 2018 Nov 17. pii: S1499-2671(18)30420-9. doi: 10.1016/j.jcjd.2018.11.003. [Epub ahead of print]


Determining the optimal time for liberation from renal replacement therapy in critically ill patients: protocol for a systematic review and meta-analysis (DOnE RRT).

Al Saadon A, Katulka R, Sebastianski M, Featherstone R, Vandermeer B, Gibney RTN, Rewa OG, Bagshaw SM.

BMJ Open. 2018 Nov 25;8(11):e023306. doi: 10.1136/bmjopen-2018-023306.


Association of protein intake with the outcomes of critically ill patients: a post hoc analysis of the PermiT trial.

Arabi YM, Al-Dorzi HM, Mehta S, Tamim HM, Haddad SH, Jones G, McIntyre L, Solaiman O, Sakkijha MH, Sadat M, Afesh L, Kumar A, Bagshaw SM, Aldawood AS; PermiT Trial Group.

Am J Clin Nutr. 2018 Nov 1;108(5):988-996. doi: 10.1093/ajcn/nqy189.


Polymyxin B hemoperfusion in endotoxemic septic shock patients without extreme endotoxemia: a post hoc analysis of the EUPHRATES trial.

Klein DJ, Foster D, Walker PM, Bagshaw SM, Mekonnen H, Antonelli M.

Intensive Care Med. 2018 Dec;44(12):2205-2212. doi: 10.1007/s00134-018-5463-7. Epub 2018 Nov 23.


Timing of onset of persistent critical illness: a multi-centre retrospective cohort study.

Bagshaw SM, Stelfox HT, Iwashyna TJ, Bellomo R, Zuege D, Wang X.

Intensive Care Med. 2018 Dec;44(12):2134-2144. doi: 10.1007/s00134-018-5440-1. Epub 2018 Nov 12.


Comparison of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Management Strategies Before Cardiac Surgery: A Pilot Randomized Controlled Registry Trial.

van Diepen S, Norris CM, Zheng Y, Nagendran J, Graham MM, Gaete Ortega D, Townsend DR, Ezekowitz JA, Bagshaw SM.

J Am Heart Assoc. 2018 Oct 16;7(20):e009917. doi: 10.1161/JAHA.118.009917.


Effect of Targeted Polymyxin B Hemoperfusion on 28-Day Mortality in Patients With Septic Shock and Elevated Endotoxin Level: The EUPHRATES Randomized Clinical Trial.

Dellinger RP, Bagshaw SM, Antonelli M, Foster DM, Klein DJ, Marshall JC, Palevsky PM, Weisberg LS, Schorr CA, Trzeciak S, Walker PM; EUPHRATES Trial Investigators.

JAMA. 2018 Oct 9;320(14):1455-1463. doi: 10.1001/jama.2018.14618.


Implementing Frailty Measures in the Canadian Healthcare System.

Rolfson DB, Heckman GA, Bagshaw SM, Robertson D, Hirdes JP.

J Frailty Aging. 2018;7(4):208-216. doi: 10.14283/jfa.2018.29.


Venous Thromboembolism Prophylaxis in Neurocritical Care Patients: Are Current Practices, Best Practices?

Sauro KM, Soo A, Kramer A, Couillard P, Kromm J, Zygun D, Niven DJ, Bagshaw SM, Stelfox HT.

Neurocrit Care. 2019 Apr;30(2):355-363. doi: 10.1007/s12028-018-0614-9.


Frailty and the Association Between Long-Term Recovery After Intensive Care Unit Admission.

Montgomery CL, Rolfson DB, Bagshaw SM.

Crit Care Clin. 2018 Oct;34(4):527-547. doi: 10.1016/j.ccc.2018.06.007. Epub 2018 Aug 11. Review.


A cluster randomised, crossover, registry-embedded clinical trial of proton pump inhibitors versus histamine-2 receptor blockers for ulcer prophylaxis therapy in the intensive care unit (PEPTIC study): study protocol.

Young PJ, Bagshaw SM, Forbes A, Nichol A, Wright SE, Bellomo R, Bailey MJ, Beasley RW, Eastwood GM, Festa M, Gattas D, van Haren F, Litton E, Mouncey PR, Navarra L, Pilcher D, Mackle DM, McArthur CJ, McGuinness SP, Saxena MK, Webb S, Rowan KM; Australian and New Zealand Intensive Care Society Clinical Trials Group on behalf of the PEPTIC investigators.

Crit Care Resusc. 2018 Sep;20(3):182-189.


Six-Month Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery.

Mazer CD, Whitlock RP, Fergusson DA, Belley-Cote E, Connolly K, Khanykin B, Gregory AJ, de Médicis É, Carrier FM, McGuinness S, Young PJ, Byrne K, Villar JC, Royse A, Grocott HP, Seeberger MD, Mehta C, Lellouche F, Hare GMT, Painter TW, Fremes S, Syed S, Bagshaw SM, Hwang NC, Royse C, Hall J, Dai D, Mistry N, Thorpe K, Verma S, Jüni P, Shehata N; TRICS Investigators and Perioperative Anesthesia Clinical Trials Group.

N Engl J Med. 2018 Sep 27;379(13):1224-1233. doi: 10.1056/NEJMoa1808561. Epub 2018 Aug 26.


Global epidemiology and outcomes of acute kidney injury.

Hoste EAJ, Kellum JA, Selby NM, Zarbock A, Palevsky PM, Bagshaw SM, Goldstein SL, Cerdá J, Chawla LS.

Nat Rev Nephrol. 2018 Oct;14(10):607-625. doi: 10.1038/s41581-018-0052-0. Review.


Perspectives on strained intensive care unit capacity: A survey of critical care professionals.

Opgenorth D, Stelfox HT, Gilfoyle E, Gibney RTN, Meier M, Boucher P, McKinlay D, Job McIntosh CN, Wang X, Zygun DA, Bagshaw SM.

PLoS One. 2018 Aug 22;13(8):e0201524. doi: 10.1371/journal.pone.0201524. eCollection 2018.


Assessment of the Safety of Discharging Select Patients Directly Home From the Intensive Care Unit: A Multicenter Population-Based Cohort Study.

Stelfox HT, Soo A, Niven DJ, Fiest KM, Wunsch H, Rowan KM, Bagshaw SM.

JAMA Intern Med. 2018 Oct 1;178(10):1390-1399. doi: 10.1001/jamainternmed.2018.3675.


Secondary EMR data for quality improvement and research: A comparison of manual and electronic data collection from an integrated critical care electronic medical record system.

Brundin-Mather R, Soo A, Zuege DJ, Niven DJ, Fiest K, Doig CJ, Zygun D, Boyd JM, Parsons Leigh J, Bagshaw SM, Stelfox HT.

J Crit Care. 2018 Oct;47:295-301. doi: 10.1016/j.jcrc.2018.07.021. Epub 2018 Jul 22.


A modified Delphi process to identify, rank and prioritize quality indicators for continuous renal replacement therapy (CRRT) care in critically ill patients.

Rewa OG, Eurich DT, Noel Gibney RT, Bagshaw SM.

J Crit Care. 2018 Oct;47:145-152. doi: 10.1016/j.jcrc.2018.06.023. Epub 2018 Jun 30.


Patient, family and provider experiences with transfers from intensive care unit to hospital ward: a multicentre qualitative study.

de Grood C, Leigh JP, Bagshaw SM, Dodek PM, Fowler RA, Forster AJ, Boyd JM, Stelfox HT.

CMAJ. 2018 Jun 4;190(22):E669-E676. doi: 10.1503/cmaj.170588.


A Multicenter Observational Study of Family Participation in ICU Rounds.

Au SS, Roze des Ordons AL, Parsons Leigh J, Soo A, Guienguere S, Bagshaw SM, Stelfox HT.

Crit Care Med. 2018 Aug;46(8):1255-1262. doi: 10.1097/CCM.0000000000003193.


Intermittent furosemide administration in patients with or at risk for acute kidney injury: Meta-analysis of randomized trials.

Bove T, Belletti A, Putzu A, Pappacena S, Denaro G, Landoni G, Bagshaw SM, Zangrillo A.

PLoS One. 2018 Apr 24;13(4):e0196088. doi: 10.1371/journal.pone.0196088. eCollection 2018.


Association between afterhours admission to the intensive care unit, strained capacity, and mortality: a retrospective cohort study.

Hall AM, Stelfox HT, Wang X, Chen G, Zuege DJ, Dodek P, Garland A, Scales DC, Berthiaume L, Zygun DA, Bagshaw SM.

Crit Care. 2018 Apr 17;22(1):97. doi: 10.1186/s13054-018-2027-8.


Indications and Timing of Continuous Renal Replacement Therapy Application.

Bagshaw SM, Wald R.

Contrib Nephrol. 2018;194:25-37. doi: 10.1159/000485598. Epub 2018 Mar 29.


Indicators of intensive care unit capacity strain: a systematic review.

Rewa OG, Stelfox HT, Ingolfsson A, Zygun DA, Featherstone R, Opgenorth D, Bagshaw SM.

Crit Care. 2018 Mar 27;22(1):86. doi: 10.1186/s13054-018-1975-3. Review.


Assessing frailty in the intensive care unit: A reliability and validity study.

Shears M, Takaoka A, Rochwerg B, Bagshaw SM, Johnstone J, Holding A, Tharmalingam S, Millen T, Clarke F, Rockwood K, Li G, Thabane L, Muscedere J, Stelfox HT, Cook DJ; Canadian Critical Care Trials Group.

J Crit Care. 2018 Jun;45:197-203. doi: 10.1016/j.jcrc.2018.02.004. Epub 2018 Feb 8.


Biomarkers for prediction of renal replacement therapy in acute kidney injury: a systematic review and meta-analysis.

Klein SJ, Brandtner AK, Lehner GF, Ulmer H, Bagshaw SM, Wiedermann CJ, Joannidis M.

Intensive Care Med. 2018 Mar;44(3):323-336. doi: 10.1007/s00134-018-5126-8. Epub 2018 Mar 14. Review.


Impact of nighttime Rapid Response Team activation on outcomes of hospitalized patients with acute deterioration.

Fernando SM, Reardon PM, Bagshaw SM, Scales DC, Murphy K, Shen J, Tanuseputro P, Heyland DK, Kyeremanteng K.

Crit Care. 2018 Mar 14;22(1):67. doi: 10.1186/s13054-018-2005-1.


Fluid Therapy in the Critically Ill.

Shaw AD, Bagshaw SM.

Crit Care Clin. 2018 Apr;34(2):xiii-xiv. doi: 10.1016/j.ccc.2018.01.002. No abstract available.


Interventions to prevent hemodynamic instability during renal replacement therapy in critically ill patients: a systematic review.

Douvris A, Malhi G, Hiremath S, McIntyre L, Silver SA, Bagshaw SM, Wald R, Ronco C, Sikora L, Weber C, Clark EG.

Crit Care. 2018 Feb 22;22(1):41. doi: 10.1186/s13054-018-1965-5. Review.


7 versus 14 days of antibiotic treatment for critically ill patients with bloodstream infection: a pilot randomized clinical trial.

Daneman N, Rishu AH, Pinto R, Aslanian P, Bagshaw SM, Carignan A, Charbonney E, Coburn B, Cook DJ, Detsky ME, Dodek P, Hall R, Kumar A, Lamontagne F, Lauzier F, Marshall JC, Martin CM, McIntyre L, Muscedere J, Reynolds S, Sligl W, Stelfox HT, Wilcox ME, Fowler RA; Canadian Critical Care Trials Group.

Trials. 2018 Feb 17;19(1):111. doi: 10.1186/s13063-018-2474-1.


Acute Kidney Injury and Big Data.

Sutherland SM, Goldstein SL, Bagshaw SM.

Contrib Nephrol. 2018;193:55-67. doi: 10.1159/000484963. Epub 2018 Jan 23.


Transfers from intensive care unit to hospital ward: a multicentre textual analysis of physician progress notes.

Brown KN, Leigh JP, Kamran H, Bagshaw SM, Fowler RA, Dodek PM, Turgeon AF, Forster AJ, Lamontagne F, Soo A, Stelfox HT.

Crit Care. 2018 Jan 28;22(1):19. doi: 10.1186/s13054-018-1941-0.


Association Between Fluid Balance and Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis.

Alobaidi R, Morgan C, Basu RK, Stenson E, Featherstone R, Majumdar SR, Bagshaw SM.

JAMA Pediatr. 2018 Mar 1;172(3):257-268. doi: 10.1001/jamapediatrics.2017.4540.


Correction to: Polymyxin B-immobilized hemoperfusion and mortality in critically ill adult patients with sepsis/septic shock: a systematic review with meta-analysis and trial sequential analysis.

Fujii T, Ganeko R, Kataoka Y, Furukawa TA, Featherstone R, Doi K, Vincent JL, Pasero D, Robert R, Ronco C, Bagshaw SM.

Intensive Care Med. 2018 Feb;44(2):279-280. doi: 10.1007/s00134-018-5055-6.


Risk of Acute Kidney Injury in Patients Randomized to a Restrictive Versus Liberal Approach to Red Blood Cell Transfusion in Cardiac Surgery: A Substudy Protocol of the Transfusion Requirements in Cardiac Surgery III Noninferiority Trial.

Garg AX, Shehata N, McGuinness S, Whitlock R, Fergusson D, Wald R, Parikh C, Bagshaw SM, Khanykin B, Gregory A, Syed S, Hare GMT, Cuerden MS, Thorpe KE, Hall J, Verma S, Roshanov PS, Sontrop JM, Mazer CD.

Can J Kidney Health Dis. 2018 Jan 3;5:2054358117749532. doi: 10.1177/2054358117749532. eCollection 2018.


Polymyxin B-immobilized hemoperfusion and mortality in critically ill adult patients with sepsis/septic shock: a systematic review with meta-analysis and trial sequential analysis.

Fujii T, Ganeko R, Kataoka Y, Furukawa TA, Featherstone R, Doi K, Vincent JL, Pasero D, Robert R, Ronco C, Bagshaw SM.

Intensive Care Med. 2018 Feb;44(2):167-178. doi: 10.1007/s00134-017-5004-9. Epub 2017 Dec 4. Erratum in: Intensive Care Med. 2018 Jan 16;:.


Interobserver agreement for post mortem renal histopathology and diagnosis of acute tubular necrosis in critically ill patients.

Glassford NJ, Skene A, Guardiola MB, Chan MJ, Bagshaw SM, Bellomo R, Solez K.

Crit Care Resusc. 2017 Dec;19(4):337-343.


Incidence, correlates and outcomes associated with falls in the intensive care unit: a retrospective cohort study.

Trumble D, Meier MA, Doody M, Wang X, Bagshaw SM.

Crit Care Resusc. 2017 Dec;19(4):290-295.


Kinetics of Urinary Cell Cycle Arrest Markers for Acute Kidney Injury Following Exposure to Potential Renal Insults.

Ostermann M, McCullough PA, Forni LG, Bagshaw SM, Joannidis M, Shi J, Kashani K, Honore PM, Chawla LS, Kellum JA; all SAPPHIRE Investigators.

Crit Care Med. 2018 Mar;46(3):375-383. doi: 10.1097/CCM.0000000000002847.


Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery.

Mazer CD, Whitlock RP, Fergusson DA, Hall J, Belley-Cote E, Connolly K, Khanykin B, Gregory AJ, de Médicis É, McGuinness S, Royse A, Carrier FM, Young PJ, Villar JC, Grocott HP, Seeberger MD, Fremes S, Lellouche F, Syed S, Byrne K, Bagshaw SM, Hwang NC, Mehta C, Painter TW, Royse C, Verma S, Hare GMT, Cohen A, Thorpe KE, Jüni P, Shehata N; TRICS Investigators and Perioperative Anesthesia Clinical Trials Group.

N Engl J Med. 2017 Nov 30;377(22):2133-2144. doi: 10.1056/NEJMoa1711818. Epub 2017 Nov 12.


Frailty in the age of VIPs (very old intensive care patients).

Montgomery C, Bagshaw SM.

Intensive Care Med. 2017 Dec;43(12):1887-1888. doi: 10.1007/s00134-017-4974-y. Epub 2017 Oct 30. No abstract available.


Management of Acute Respiratory Distress Syndrome and Refractory Hypoxemia. A Multicenter Observational Study.

Duan EH, Adhikari NKJ, D'Aragon F, Cook DJ, Mehta S, Alhazzani W, Goligher E, Charbonney E, Arabi YM, Karachi T, Turgeon AF, Hand L, Zhou Q, Austin P, Friedrich J, Lamontagne F, Lauzier F, Patel R, Muscedere J, Hall R, Aslanian P, Piraino T, Albert M, Bagshaw SM, Jacka M, Wood G, Henderson W, Dorscheid D, Ferguson ND, Meade MO; Canadian Critical Care Trials Group.

Ann Am Thorac Soc. 2017 Dec;14(12):1818-1826. doi: 10.1513/AnnalsATS.201612-1042OC.


Association between strained capacity and mortality among patients admitted to intensive care: A path-analysis modeling strategy.

Bagshaw SM, Wang X, Zygun DA, Zuege D, Dodek P, Garland A, Scales DC, Berthiaume L, Faris P, Chen G, Opgenorth D, Stelfox HT.

J Crit Care. 2018 Feb;43:81-87. doi: 10.1016/j.jcrc.2017.08.032. Epub 2017 Aug 24.


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