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Critical Care Strategic Clinical Network: Information infrastructure ensures a learning health system.

Bowker SL, Stelfox HT, Bagshaw SM; Critical Care Strategic Clinical Network.

CMAJ. 2019 Dec 4;191(Suppl):S22-S23. doi: 10.1503/cmaj.190578. No abstract available.


Frailty and associated outcomes and resource utilization following in-hospital cardiac arrest.

Fernando SM, McIsaac DI, Rochwerg B, Cook DJ, Bagshaw SM, Muscedere J, Munshi L, Nolan JP, Perry JJ, Downar J, Dave C, Reardon PM, Tanuseputro P, Kyeremanteng K.

Resuscitation. 2019 Nov 27. pii: S0300-9572(19)30701-4. doi: 10.1016/j.resuscitation.2019.11.011. [Epub ahead of print]


O2, do we know what to do?

Young PJ, Bagshaw SM, Bailey M, Bellomo R, Mackle D, Pilcher D, Landoni G, Nichol A, Martin D.

Crit Care Resusc. 2019 Dec;21(4):230-32. No abstract available.


Net Ultrafiltration Prescription and Practice Among Critically Ill Patients Receiving Renal Replacement Therapy: A Multinational Survey of Critical Care Practitioners.

Murugan R, Ostermann M, Peng Z, Kitamura K, Fujitani S, Romagnoli S, Di Lullo L, Srisawat N, Todi S, Ramakrishnan N, Hoste E, Puttarajappa CM, Bagshaw SM, Weisbord S, Palevsky PM, Kellum JA, Bellomo R, Ronco C.

Crit Care Med. 2019 Nov 13. doi: 10.1097/CCM.0000000000004092. [Epub ahead of print]


Patient characteristics, ICU-specific supports, complications, and outcomes of persistent critical illness.

Jeffcote T, Foong M, Gold G, Glassford N, Robbins R, Iwashyna TJ, Darvall J, Bagshaw SM, Bellomo R.

J Crit Care. 2019 Dec;54:250-255. doi: 10.1016/j.jcrc.2019.08.023. Epub 2019 Aug 20.


Frailty and invasive mechanical ventilation: association with outcomes, extubation failure, and tracheostomy.

Fernando SM, McIsaac DI, Rochwerg B, Bagshaw SM, Muscedere J, Munshi L, Ferguson ND, Seely AJE, Cook DJ, Dave C, Tanuseputro P, Kyeremanteng K.

Intensive Care Med. 2019 Dec;45(12):1742-1752. doi: 10.1007/s00134-019-05795-8. Epub 2019 Oct 8.


The impact of cirrhosis in patients undergoing cardiac surgery: a retrospective observational cohort study.

Xavier S, Norris CM, Ewasiuk A, Kutsogiannis DJ, Bagshaw SM, van Diepen S, Townsend DR, Negendran J, Karvellas CJ.

Can J Anaesth. 2019 Sep 30. doi: 10.1007/s12630-019-01493-7. [Epub ahead of print]


Population-Based Epidemiology and Outcomes of Acute Kidney Injury in Critically Ill Children.

Alobaidi R, Morgan C, Goldstein SL, Bagshaw SM.

Pediatr Crit Care Med. 2019 Sep 20. doi: 10.1097/PCC.0000000000002128. [Epub ahead of print]


Frailty in very old critically ill patients in Australia and New Zealand: a population-based cohort study.

Darvall JN, Bellomo R, Paul E, Subramaniam A, Santamaria JD, Bagshaw SM, Rai S, Hubbard RE, Pilcher D.

Med J Aust. 2019 Oct;211(7):318-323. doi: 10.5694/mja2.50329. Epub 2019 Sep 5.


Prospective validation and refinement of the APPROACH cardiovascular surgical intensive care unit readmission score.

Verma S, Southern DA, Raslan IR, Norris CM, Graham MM, Bagshaw SM, Nagendran J, Maclure T, Sun LY, Chin WD, van Diepen S.

J Crit Care. 2019 Dec;54:117-121. doi: 10.1016/j.jcrc.2019.08.018. Epub 2019 Aug 9.


Mechanisms for hemodynamic instability related to renal replacement therapy: a narrative review.

Douvris A, Zeid K, Hiremath S, Bagshaw SM, Wald R, Beaubien-Souligny W, Kong J, Ronco C, Clark EG.

Intensive Care Med. 2019 Oct;45(10):1333-1346. doi: 10.1007/s00134-019-05707-w. Epub 2019 Aug 12. Review.


Intraoperative continuous renal replacement therapy during liver transplantation: a pilot randomized-controlled trial (INCEPTION).

Karvellas CJ, Taylor S, Bigam D, Kneteman NM, Shapiro AMJ, Romanovsky A, Gibney RTN, Townsend DR, Meeberg G, Özelsel T, Bishop E, Bagshaw SM.

Can J Anaesth. 2019 Oct;66(10):1151-1161. doi: 10.1007/s12630-019-01454-0. Epub 2019 Jul 26.


Quality of care and safety measures of acute renal replacement therapy: Workgroup statements from the 22nd acute disease quality initiative (ADQI) consensus conference.

Rewa OG, Tolwani A, Mottes T, Juncos LA, Ronco C, Kashani K, Rosner M, Haase M, Kellum J, Bagshaw SM; ADQI Consensus Meeting Members on behalf of ADQI XXII.

J Crit Care. 2019 Dec;54:52-57. doi: 10.1016/j.jcrc.2019.07.003. Epub 2019 Jul 5.


Retrospective frailty determination in critical illness from a review of the intensive care unit clinical record.

Darvall JN, Boonstra T, Norman J, Murphy D, Bailey M, Iwashyna TJ, Bagshaw SM, Bellomo R.

Anaesth Intensive Care. 2019 Jul;47(4):343-348. doi: 10.1177/0310057X19856895. Epub 2019 Jul 25. No abstract available.


What determines do-not-resuscitate status in critically ill HIV-infected patients admitted to ICU?

Gregory AB, Turvey SL, Bagshaw SM, Sligl WI.

J Crit Care. 2019 Oct;53:207-211. doi: 10.1016/j.jcrc.2019.06.010. Epub 2019 Jun 19.


Safety of a Restrictive versus Liberal Approach to Red Blood Cell Transfusion on the Outcome of AKI in Patients Undergoing Cardiac Surgery: A Randomized Clinical Trial.

Garg AX, Badner N, Bagshaw SM, Cuerden MS, Fergusson DA, Gregory AJ, Hall J, Hare GMT, Khanykin B, McGuinness S, Parikh CR, Roshanov PS, Shehata N, Sontrop JM, Syed S, Tagarakis GI, Thorpe KE, Verma S, Wald R, Whitlock RP, Mazer CD; TRICS Investigators and Perioperative Anesthesia Clinical Trials Group.

J Am Soc Nephrol. 2019 Jul;30(7):1294-1304. doi: 10.1681/ASN.2019010004. Epub 2019 Jun 20.


Implementation of population-level screening for frailty among patients admitted to adult intensive care in Alberta, Canada.

Montgomery CL, Zuege DJ, Rolfson DB, Opgenorth D, Hudson D, Stelfox HT, Bagshaw SM.

Can J Anaesth. 2019 Nov;66(11):1310-1319. doi: 10.1007/s12630-019-01414-8. Epub 2019 May 29.


Persistent critical illness: baseline characteristics, intensive care course, and cause of death.

Darvall JN, Boonstra T, Norman J, Murphy D, Bailey M, Iwashyna TJ, Bagshaw SM, Bellomo R.

Crit Care Resusc. 2019 Jun;21(2):110-118.


Frailty and Associated Outcomes and Resource Utilization Among Older ICU Patients With Suspected Infection.

Fernando SM, McIsaac DI, Perry JJ, Rochwerg B, Bagshaw SM, Thavorn K, Seely AJE, Forster AJ, Fiest KM, Dave C, Tran A, Reardon PM, Tanuseputro P, Kyeremanteng K.

Crit Care Med. 2019 Aug;47(8):e669-e676. doi: 10.1097/CCM.0000000000003831.


Quality Improvement Goals for Acute Kidney Injury.

Kashani K, Rosner MH, Haase M, Lewington AJP, O'Donoghue DJ, Wilson FP, Nadim MK, Silver SA, Zarbock A, Ostermann M, Mehta RL, Kane-Gill SL, Ding X, Pickkers P, Bihorac A, Siew ED, Barreto EF, Macedo E, Kellum JA, Palevsky PM, Tolwani AJ, Ronco C, Juncos LA, Rewa OG, Bagshaw SM, Mottes TA, Koyner JL, Liu KD, Forni LG, Heung M, Wu VC.

Clin J Am Soc Nephrol. 2019 Jun 7;14(6):941-953. doi: 10.2215/CJN.01250119. Epub 2019 May 17.


The furosemide stress test for prediction of worsening acute kidney injury in critically ill patients: A multicenter, prospective, observational study.

Rewa OG, Bagshaw SM, Wang X, Wald R, Smith O, Shapiro J, McMahon B, Liu KD, Trevino SA, Chawla LS, Koyner JL.

J Crit Care. 2019 Aug;52:109-114. doi: 10.1016/j.jcrc.2019.04.011. Epub 2019 Apr 9.


Association between harm reduction strategies and healthcare utilization in patients on long-term prescribed opioid therapy presenting to acute healthcare settings: a protocol for a systematic review and meta-analysis.

Deschamps J, Gilbertson J, Straube S, Dong K, MacMaster FP, Korownyk C, Montgomery L, Mahaffey R, Downar J, Clarke H, Muscedere J, Rittenbach K, Featherstone R, Sebastianski M, Vandermeer B, Lynam D, Magnussen R, Bagshaw SM, Rewa OG.

Syst Rev. 2019 Apr 5;8(1):88. doi: 10.1186/s13643-019-0997-5.


Selection and Receipt of Kidney Replacement in Critically Ill Older Patients with AKI.

Bagshaw SM, Adhikari NKJ, Burns KEA, Friedrich JO, Bouchard J, Lamontagne F, McIntrye LA, Cailhier JF, Dodek P, Stelfox HT, Herridge M, Lapinsky S, Muscedere J, Barton J, Griesdale D, Soth M, Ambosta A, Lebovic G, Wald R; Canadian Critical Care Trials Group.

Clin J Am Soc Nephrol. 2019 Apr 5;14(4):496-505. doi: 10.2215/CJN.05530518. Epub 2019 Mar 21.


Barriers and facilitators to adopting high value practices and de-adopting low value practices in Canadian intensive care units: a multimethod study.

Sauro K, Bagshaw SM, Niven D, Soo A, Brundin-Mather R, Parsons Leigh J, Cook DJ, Stelfox HT.

BMJ Open. 2019 Mar 15;9(3):e024159. doi: 10.1136/bmjopen-2018-024159.


Association between strained ICU capacity and healthcare costs in Canada: A population-based cohort study.

Tran DT, Thanh NX, Opgenorth D, Wang X, Zuege D, Zygun DA, Stelfox HT, Bagshaw SM.

J Crit Care. 2019 Jun;51:175-183. doi: 10.1016/j.jcrc.2019.02.025. Epub 2019 Feb 26.


Relaxation for Critically ill Patient Outcomes and Stress-coping Enhancement (REPOSE): a protocol for a pilot randomised trial of an integrative intervention to improve critically ill patients' delirium and related outcomes.

Papathanassoglou EDE, Skrobik Y, Hegadoren K, Thompson P, Stelfox HT, Norris C, Rose L, Bagshaw SM, Meier M, LoCicero C, Ashmore R, Sparrow Brulotte T, Hassan I, Park T, Kutsogiannis DJ.

BMJ Open. 2019 Jan 15;9(1):e023961. doi: 10.1136/bmjopen-2018-023961.


Brain natriuretic peptide to predict successful liberation from mechanical ventilation in critically ill patients: protocol for a systematic review and meta-analysis.

Deschamps J, Webber J, Featherstone R, Sebastianski M, Vandermeer B, Senaratne J, Bagshaw SM.

BMJ Open. 2019 Feb 12;9(2):e022600. doi: 10.1136/bmjopen-2018-022600.


Atrial natriuretic peptide for treatment of acute kidney injury (AKI) - Initiate an optimal dose early.

Ricksten SE, Bagshaw SM.

J Crit Care. 2019 Jun;51:236-237. doi: 10.1016/j.jcrc.2018.12.013. Epub 2018 Dec 26. No abstract available.


A multicentre controlled pre-post trial of an implementation science intervention to improve venous thromboembolism prophylaxis in critically ill patients.

Stelfox HT, Brundin-Mather R, Soo A, Parsons Leigh J, Niven DJ, Fiest KM, Doig CJ, Zuege DJ, Kushner B, Clement F, Straus SE, Cook DJ, Bagshaw SM, Sauro KM.

Intensive Care Med. 2019 Feb;45(2):211-222. doi: 10.1007/s00134-019-05532-1. Epub 2019 Feb 1.


Caloric intake and the fat-to-carbohydrate ratio in hypercapnic acute respiratory failure: Post-hoc analysis of the PermiT trial.

Al-Dorzi HM, Aldawood AS, Tamim H, Haddad SH, Jones G, McIntyre L, Solaiman O, Sakhija M, Sadat M, Afesh L, Kumar A, Bagshaw SM, Mehta S, M Arabi Y.

Clin Nutr ESPEN. 2019 Feb;29:175-182. doi: 10.1016/j.clnesp.2018.10.012. Epub 2018 Nov 13.


Comparison of outcomes and costs between adult diabetic ketoacidosis patients admitted to the ICU and step-down unit.

Fernando SM, Bagshaw SM, Rochwerg B, McIsaac DI, Thavorn K, Forster AJ, Tran A, Reardon PM, Rosenberg E, Tanuseputro P, Kyeremanteng K.

J Crit Care. 2019 Apr;50:257-261. doi: 10.1016/j.jcrc.2018.12.014. Epub 2018 Dec 25.


Acute Management of Diabetic Ketoacidosis in Adults at 3 Teaching Hospitals in Canada: A Multicentre, Retrospective Cohort Study.

Galm BP, Bagshaw SM, Senior PA.

Can J Diabetes. 2019 Jul;43(5):309-315.e2. doi: 10.1016/j.jcjd.2018.11.003. Epub 2018 Nov 17.


Determining the optimal time for liberation from renal replacement therapy in critically ill patients: protocol for a systematic review and meta-analysis (DOnE RRT).

Al Saadon A, Katulka R, Sebastianski M, Featherstone R, Vandermeer B, Gibney RTN, Rewa OG, Bagshaw SM.

BMJ Open. 2018 Nov 25;8(11):e023306. doi: 10.1136/bmjopen-2018-023306.


Association of protein intake with the outcomes of critically ill patients: a post hoc analysis of the PermiT trial.

Arabi YM, Al-Dorzi HM, Mehta S, Tamim HM, Haddad SH, Jones G, McIntyre L, Solaiman O, Sakkijha MH, Sadat M, Afesh L, Kumar A, Bagshaw SM, Aldawood AS; PermiT Trial Group.

Am J Clin Nutr. 2018 Nov 1;108(5):988-996. doi: 10.1093/ajcn/nqy189.


Polymyxin B hemoperfusion in endotoxemic septic shock patients without extreme endotoxemia: a post hoc analysis of the EUPHRATES trial.

Klein DJ, Foster D, Walker PM, Bagshaw SM, Mekonnen H, Antonelli M.

Intensive Care Med. 2018 Dec;44(12):2205-2212. doi: 10.1007/s00134-018-5463-7. Epub 2018 Nov 23.


Timing of onset of persistent critical illness: a multi-centre retrospective cohort study.

Bagshaw SM, Stelfox HT, Iwashyna TJ, Bellomo R, Zuege D, Wang X.

Intensive Care Med. 2018 Dec;44(12):2134-2144. doi: 10.1007/s00134-018-5440-1. Epub 2018 Nov 12.


Comparison of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Management Strategies Before Cardiac Surgery: A Pilot Randomized Controlled Registry Trial.

van Diepen S, Norris CM, Zheng Y, Nagendran J, Graham MM, Gaete Ortega D, Townsend DR, Ezekowitz JA, Bagshaw SM.

J Am Heart Assoc. 2018 Oct 16;7(20):e009917. doi: 10.1161/JAHA.118.009917.


Effect of Targeted Polymyxin B Hemoperfusion on 28-Day Mortality in Patients With Septic Shock and Elevated Endotoxin Level: The EUPHRATES Randomized Clinical Trial.

Dellinger RP, Bagshaw SM, Antonelli M, Foster DM, Klein DJ, Marshall JC, Palevsky PM, Weisberg LS, Schorr CA, Trzeciak S, Walker PM; EUPHRATES Trial Investigators.

JAMA. 2018 Oct 9;320(14):1455-1463. doi: 10.1001/jama.2018.14618.


Implementing Frailty Measures in the Canadian Healthcare System.

Rolfson DB, Heckman GA, Bagshaw SM, Robertson D, Hirdes JP.

J Frailty Aging. 2018;7(4):208-216. doi: 10.14283/jfa.2018.29.


Venous Thromboembolism Prophylaxis in Neurocritical Care Patients: Are Current Practices, Best Practices?

Sauro KM, Soo A, Kramer A, Couillard P, Kromm J, Zygun D, Niven DJ, Bagshaw SM, Stelfox HT.

Neurocrit Care. 2019 Apr;30(2):355-363. doi: 10.1007/s12028-018-0614-9.


Frailty and the Association Between Long-Term Recovery After Intensive Care Unit Admission.

Montgomery CL, Rolfson DB, Bagshaw SM.

Crit Care Clin. 2018 Oct;34(4):527-547. doi: 10.1016/j.ccc.2018.06.007. Epub 2018 Aug 11. Review.


A cluster randomised, crossover, registry-embedded clinical trial of proton pump inhibitors versus histamine-2 receptor blockers for ulcer prophylaxis therapy in the intensive care unit (PEPTIC study): study protocol.

Young PJ, Bagshaw SM, Forbes A, Nichol A, Wright SE, Bellomo R, Bailey MJ, Beasley RW, Eastwood GM, Festa M, Gattas D, van Haren F, Litton E, Mouncey PR, Navarra L, Pilcher D, Mackle DM, McArthur CJ, McGuinness SP, Saxena MK, Webb S, Rowan KM; Australian and New Zealand Intensive Care Society Clinical Trials Group on behalf of the PEPTIC investigators.

Crit Care Resusc. 2018 Sep;20(3):182-189.


Six-Month Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery.

Mazer CD, Whitlock RP, Fergusson DA, Belley-Cote E, Connolly K, Khanykin B, Gregory AJ, de Médicis É, Carrier FM, McGuinness S, Young PJ, Byrne K, Villar JC, Royse A, Grocott HP, Seeberger MD, Mehta C, Lellouche F, Hare GMT, Painter TW, Fremes S, Syed S, Bagshaw SM, Hwang NC, Royse C, Hall J, Dai D, Mistry N, Thorpe K, Verma S, Jüni P, Shehata N; TRICS Investigators and Perioperative Anesthesia Clinical Trials Group.

N Engl J Med. 2018 Sep 27;379(13):1224-1233. doi: 10.1056/NEJMoa1808561. Epub 2018 Aug 26.


Global epidemiology and outcomes of acute kidney injury.

Hoste EAJ, Kellum JA, Selby NM, Zarbock A, Palevsky PM, Bagshaw SM, Goldstein SL, Cerdá J, Chawla LS.

Nat Rev Nephrol. 2018 Oct;14(10):607-625. doi: 10.1038/s41581-018-0052-0. Review.


Perspectives on strained intensive care unit capacity: A survey of critical care professionals.

Opgenorth D, Stelfox HT, Gilfoyle E, Gibney RTN, Meier M, Boucher P, McKinlay D, Job McIntosh CN, Wang X, Zygun DA, Bagshaw SM.

PLoS One. 2018 Aug 22;13(8):e0201524. doi: 10.1371/journal.pone.0201524. eCollection 2018.


Assessment of the Safety of Discharging Select Patients Directly Home From the Intensive Care Unit: A Multicenter Population-Based Cohort Study.

Stelfox HT, Soo A, Niven DJ, Fiest KM, Wunsch H, Rowan KM, Bagshaw SM.

JAMA Intern Med. 2018 Oct 1;178(10):1390-1399. doi: 10.1001/jamainternmed.2018.3675.


Secondary EMR data for quality improvement and research: A comparison of manual and electronic data collection from an integrated critical care electronic medical record system.

Brundin-Mather R, Soo A, Zuege DJ, Niven DJ, Fiest K, Doig CJ, Zygun D, Boyd JM, Parsons Leigh J, Bagshaw SM, Stelfox HT.

J Crit Care. 2018 Oct;47:295-301. doi: 10.1016/j.jcrc.2018.07.021. Epub 2018 Jul 22.


A modified Delphi process to identify, rank and prioritize quality indicators for continuous renal replacement therapy (CRRT) care in critically ill patients.

Rewa OG, Eurich DT, Noel Gibney RT, Bagshaw SM.

J Crit Care. 2018 Oct;47:145-152. doi: 10.1016/j.jcrc.2018.06.023. Epub 2018 Jun 30.


Patient, family and provider experiences with transfers from intensive care unit to hospital ward: a multicentre qualitative study.

de Grood C, Leigh JP, Bagshaw SM, Dodek PM, Fowler RA, Forster AJ, Boyd JM, Stelfox HT.

CMAJ. 2018 Jun 4;190(22):E669-E676. doi: 10.1503/cmaj.170588.


A Multicenter Observational Study of Family Participation in ICU Rounds.

Au SS, Roze des Ordons AL, Parsons Leigh J, Soo A, Guienguere S, Bagshaw SM, Stelfox HT.

Crit Care Med. 2018 Aug;46(8):1255-1262. doi: 10.1097/CCM.0000000000003193.


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