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Items: 50

1.

The role of enhancer of zeste homolog 2: From viral epigenetics to the carcinogenesis of hepatocellular carcinoma.

Sanna L, Marchesi I, Melone MAB, Bagella L.

J Cell Physiol. 2018 Sep;233(9):6508-6517. doi: 10.1002/jcp.26545. Epub 2018 Mar 25. Review.

PMID:
29574790
2.

A new parameter of growth inhibition for cell proliferation assays.

Fiorentino FP, Bagella L, Marchesi I.

J Cell Physiol. 2018 May;233(5):4106-4115. doi: 10.1002/jcp.26208. Epub 2017 Dec 4.

PMID:
29023715
3.

12-O-tetradecanoylphorbol-13-acetate and EZH2 inhibition: A novel approach for promoting myogenic differentiation in embryonal rhabdomyosarcoma cells.

Marchesi I, Sanna L, Fais M, Fiorentino FP, Giordano A, Bagella L.

J Cell Physiol. 2018 Mar;233(3):2360-2365. doi: 10.1002/jcp.26107. Epub 2017 Aug 30.

PMID:
28722764
4.

Correction to Synthesis and Antineoplastic Evaluation of Novel Unsymmetrical 1,3,4-Oxadiazoles.

Nieddu V, Pinna G, Marchesi I, Sanna L, Asproni B, Pinna GA, Bagella L, Murineddu G.

J Med Chem. 2017 Feb 9;60(3):1226. doi: 10.1021/acs.jmedchem.7b00052. Epub 2017 Jan 27. No abstract available.

PMID:
28128556
5.

Synthesis and Antineoplastic Evaluation of Novel Unsymmetrical 1,3,4-Oxadiazoles.

Nieddu V, Pinna G, Marchesi I, Sanna L, Asproni B, Pinna GA, Bagella L, Murineddu G.

J Med Chem. 2016 Dec 8;59(23):10451-10469. Epub 2016 Nov 29.

PMID:
27801583
6.

Targeting Enhancer of Zeste Homolog 2 as a promising strategy for cancer treatment.

Marchesi I, Bagella L.

World J Clin Oncol. 2016 Apr 10;7(2):135-48. doi: 10.5306/wjco.v7.i2.135.

7.

A Promyelocytic Leukemia Protein-Thrombospondin-2 Axis and the Risk of Relapse in Neuroblastoma.

Dvorkina M, Nieddu V, Chakelam S, Pezzolo A, Cantilena S, Leite AP, Chayka O, Regad T, Pistorio A, Sementa AR, Virasami A, Barton J, Montano X, Lechertier T, Brindle N, Morgenstern D, Lebras M, Burns AJ, Saunders NJ, Hodivala-Dilke K, Bagella L, De The H, Anderson J, Sebire N, Pistoia V, Sala A, Salomoni P.

Clin Cancer Res. 2016 Jul 1;22(13):3398-409. doi: 10.1158/1078-0432.CCR-15-2081. Epub 2016 Apr 13. Erratum in: Clin Cancer Res. 2017 Feb 1;23 (3):870.

8.

Roles of enhancer of zeste homolog 2: from skeletal muscle differentiation to rhabdomyosarcoma carcinogenesis.

Marchesi I, Giordano A, Bagella L.

Cell Cycle. 2014;13(4):516-27. doi: 10.4161/cc.27921. Epub 2014 Jan 22. Review.

PMID:
24496329
9.

Amniotic fluid stem cells morph into a cardiovascular lineage: analysis of a chemically induced cardiac and vascular commitment.

Maioli M, Contini G, Santaniello S, Bandiera P, Pigliaru G, Sanna R, Rinaldi S, Delitala AP, Montella A, Bagella L, Ventura C.

Drug Des Devel Ther. 2013 Sep 27;7:1063-73. doi: 10.2147/DDDT.S44706. eCollection 2013.

10.

Anti-senescence efficacy of radio-electric asymmetric conveyer technology.

Maioli M, Rinaldi S, Santaniello S, Castagna A, Pigliaru G, Delitala A, Lotti Margotti M, Bagella L, Fontani V, Ventura C.

Age (Dordr). 2014 Feb;36(1):9-20. doi: 10.1007/s11357-013-9537-8. Epub 2013 May 9.

11.

Sputum analysis: non-invasive early lung cancer detection.

D'Urso V, Doneddu V, Marchesi I, Collodoro A, Pirina P, Giordano A, Bagella L.

J Cell Physiol. 2013 May;228(5):945-51. doi: 10.1002/jcp.24263. Review.

PMID:
23086732
12.

Activation and function of murine Cyclin T2A and Cyclin T2B during skeletal muscle differentiation.

Marchesi I, Nieddu V, Caracciolo V, Maioli M, Gaspa L, Giordano A, Bagella L.

J Cell Biochem. 2013 Mar;114(3):728-34. doi: 10.1002/jcb.24414.

PMID:
23060074
13.

The ablation of EZH2 uncovers its crucial role in rhabdomyosarcoma formation.

Marchesi I, Fiorentino FP, Rizzolio F, Giordano A, Bagella L.

Cell Cycle. 2012 Oct 15;11(20):3828-36. doi: 10.4161/cc.22025. Epub 2012 Sep 14.

14.

Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1.

Rizzolio F, Lucchetti C, Caligiuri I, Marchesi I, Caputo M, Klein-Szanto AJ, Bagella L, Castronovo M, Giordano A.

Cell Death Differ. 2012 Jul;19(7):1152-61. doi: 10.1038/cdd.2011.202. Epub 2012 Feb 10.

15.

CTCF and BORIS regulate Rb2/p130 gene transcription: a novel mechanism and a new paradigm for understanding the biology of lung cancer.

Fiorentino FP, Macaluso M, Miranda F, Montanari M, Russo A, Bagella L, Giordano A.

Mol Cancer Res. 2011 Feb;9(2):225-33. doi: 10.1158/1541-7786.MCR-10-0493. Erratum in: Mol Cancer Res. 2013 Oct;11(10):1292.

16.

Histone deacetylase inhibitors in the treatment of hematological malignancies and solid tumors.

Federico M, Bagella L.

J Biomed Biotechnol. 2011;2011:475641. doi: 10.1155/2011/475641. Epub 2010 Dec 6. Review.

17.

Hyaluronan esters drive Smad gene expression and signaling enhancing cardiogenesis in mouse embryonic and human mesenchymal stem cells.

Maioli M, Santaniello S, Montella A, Bandiera P, Cantoni S, Cavallini C, Bianchi F, Lionetti V, Rizzolio F, Marchesi I, Bagella L, Ventura C.

PLoS One. 2010 Nov 30;5(11):e15151. doi: 10.1371/journal.pone.0015151.

18.

The BRG1 ATPase of chromatin remodeling complexes is involved in modulation of mesenchymal stem cell senescence through RB-P53 pathways.

Alessio N, Squillaro T, Cipollaro M, Bagella L, Giordano A, Galderisi U.

Oncogene. 2010 Oct 7;29(40):5452-63. doi: 10.1038/onc.2010.285. Epub 2010 Aug 9.

PMID:
20697355
19.

R-Roscovitine (Seliciclib) prevents DNA damage-induced cyclin A1 upregulation and hinders non-homologous end-joining (NHEJ) DNA repair.

Federico M, Symonds CE, Bagella L, Rizzolio F, Fanale D, Russo A, Giordano A.

Mol Cancer. 2010 Aug 4;9:208. doi: 10.1186/1476-4598-9-208.

20.

Cytometry and DNA ploidy: clinical uses and molecular perspective in gastric and lung cancer.

D'Urso V, Collodoro A, Mattioli E, Giordano A, Bagella L.

J Cell Physiol. 2010 Mar;222(3):532-9. doi: 10.1002/jcp.21991. Review.

PMID:
20020506
21.

Synthesis and cytotoxicity of novel hexahydrothienocycloheptapyridazinone derivatives.

Pau A, Murineddu G, Asproni B, Murruzzu C, Grella GE, Pinna GA, Curzu MM, Marchesi I, Bagella L.

Molecules. 2009 Sep 9;14(9):3494-508. doi: 10.3390/molecules14093494.

22.

Cdk9-55: a new player in muscle regeneration.

Giacinti C, Musarò A, De Falco G, Jourdan I, Molinaro M, Bagella L, Simone C, Giordano A.

J Cell Physiol. 2008 Sep;216(3):576-82. doi: 10.1002/jcp.21361.

PMID:
18546201
23.

From G0 to S phase: a view of the roles played by the retinoblastoma (Rb) family members in the Rb-E2F pathway.

Sun A, Bagella L, Tutton S, Romano G, Giordano A.

J Cell Biochem. 2007 Dec 15;102(6):1400-4. Review.

PMID:
17979151
24.

Importance of Ezh2 polycomb protein in tumorigenesis process interfering with the pathway of growth suppressive key elements.

Tonini T, D'Andrilli G, Fucito A, Gaspa L, Bagella L.

J Cell Physiol. 2008 Feb;214(2):295-300. Review.

PMID:
17786943
25.

Interaction between the Cdk2/cyclin A complex and a small molecule derived from the pRb2/p130 spacer domain: a theoretical model.

Giordano A, Bellacchio E, Bagella L, Paggi MG.

Cell Cycle. 2007 Nov 1;6(21):2591-3. Epub 2007 Aug 13.

PMID:
17726381
26.

Tumor suppressor pRb2/p130 gene and its derived product Spa310 spacer domain as perspective candidates for cancer therapy.

Giordano A, Rossi A, Romano G, Bagella L.

J Cell Physiol. 2007 Nov;213(2):403-6. Review.

PMID:
17708530
27.

Viral infections as a cause of cancer (review).

Carrillo-Infante C, Abbadessa G, Bagella L, Giordano A.

Int J Oncol. 2007 Jun;30(6):1521-8. Review.

PMID:
17487374
28.

A small molecule based on the pRb2/p130 spacer domain leads to inhibition of cdk2 activity, cell cycle arrest and tumor growth reduction in vivo.

Bagella L, Sun A, Tonini T, Abbadessa G, Cottone G, Paggi MG, De Luca A, Claudio PP, Giordano A.

Oncogene. 2007 Mar 22;26(13):1829-39. Epub 2006 Oct 16.

PMID:
17043661
29.

Identification of murine cdk10: association with Ets2 transcription factor and effects on the cell cycle.

Bagella L, Giacinti C, Simone C, Giordano A.

J Cell Biochem. 2006 Oct 15;99(3):978-85.

PMID:
16741970
30.

MyoD recruits the cdk9/cyclin T2 complex on myogenic-genes regulatory regions.

Giacinti C, Bagella L, Puri PL, Giordano A, Simone C.

J Cell Physiol. 2006 Mar;206(3):807-13.

PMID:
16245309
31.

pRb2/p130 decreases sensitivity to apoptosis induced by camptothecin and doxorubicin but not by taxol.

Tonini T, Gabellini C, Bagella L, D'Andrilli G, Masciullo V, Romano G, Scambia G, Zupi G, Giordano A.

Clin Cancer Res. 2004 Dec 1;10(23):8085-93.

32.

CDK9/CYCLIN T1 expression during normal lymphoid differentiation and malignant transformation.

Bellan C, De Falco G, Lazzi S, Micheli P, Vicidomini S, Schürfeld K, Amato T, Palumbo A, Bagella L, Sabattini E, Bartolommei S, Hummel M, Pileri S, Tosi P, Leoncini L, Giordano A.

J Pathol. 2004 Aug;203(4):946-52.

PMID:
15258998
33.

Frequent loss of pRb2/p130 in human ovarian carcinoma.

D'Andrilli G, Masciullo V, Bagella L, Tonini T, Minimo C, Zannoni GF, Giuntoli RL 2nd, Carlson JA Jr, Soprano DR, Soprano KJ, Scambia G, Giordano A.

Clin Cancer Res. 2004 May 1;10(9):3098-103.

34.

Ezh2 reduces the ability of HDAC1-dependent pRb2/p130 transcriptional repression of cyclin A.

Tonini T, Bagella L, D'Andrilli G, Claudio PP, Giordano A.

Oncogene. 2004 Jun 17;23(28):4930-7.

PMID:
15077161
35.

Deacetylase recruitment by the C/H3 domain of the acetyltransferase p300.

Simone C, Stiegler P, Forcales SV, Bagella L, De Luca A, Sartorelli V, Giordano A, Puri PL.

Oncogene. 2004 Mar 18;23(12):2177-87.

PMID:
14968110
36.

Study of viral integration of HPV-16 in young patients with LSIL.

Gallo G, Bibbo M, Bagella L, Zamparelli A, Sanseverino F, Giovagnoli MR, Vecchione A, Giordano A.

J Clin Pathol. 2003 Jul;56(7):532-6.

37.

Activation and function of cyclin T-Cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy.

Sano M, Abdellatif M, Oh H, Xie M, Bagella L, Giordano A, Michael LH, DeMayo FJ, Schneider MD.

Nat Med. 2002 Nov;8(11):1310-7. Epub 2002 Sep 30.

PMID:
12368904
38.

Physical interaction between pRb and cdk9/cyclinT2 complex.

Simone C, Bagella L, Bellan C, Giordano A.

Oncogene. 2002 Jun 13;21(26):4158-65.

39.

Activation of MyoD-dependent transcription by cdk9/cyclin T2.

Simone C, Stiegler P, Bagella L, Pucci B, Bellan C, De Falco G, De Luca A, Guanti G, Puri PL, Giordano A.

Oncogene. 2002 Jun 13;21(26):4137-48.

40.

Cyclin E and chromosome instability in colorectal cancer cell lines.

Simone C, Resta N, Bagella L, Giordano A, Guanti G.

Mol Pathol. 2002 Jun;55(3):200-3.

41.

Genomic organization, promoter analysis, and chromosomal mapping of the mouse gene encoding Cdk9.

Bagella L, Stiegler P, De Luca A, Siracusa LD, Giordano A.

J Cell Biochem. 2000 Apr;78(1):170-8.

PMID:
10797576
42.

Physical interaction between CDK9 and B-Myb results in suppression of B-Myb gene autoregulation.

De Falco G, Bagella L, Claudio PP, De Luca A, Fu Y, Calabretta B, Sala A, Giordano A.

Oncogene. 2000 Jan 20;19(3):373-9.

43.

Independent prognostic role of p16 expression in lung cancer.

Groeger AM, Caputi M, Esposito V, De Luca A, Bagella L, Pacilio C, Klepetko W, Giordano GG, Baldi F, Kaiser HE, Wolner E, Giordano A.

J Thorac Cardiovasc Surg. 1999 Sep;118(3):529-35.

45.

Cloning of murine CDK9/PITALRE and its tissue-specific expression in development.

Bagella L, MacLachlan TK, Buono RJ, Pisano MM, Giordano A, De Luca A.

J Cell Physiol. 1998 Nov;177(2):206-13.

PMID:
9766517
46.

A unique domain of pRb2/p130 acts as an inhibitor of Cdk2 kinase activity.

De Luca A, MacLachlan TK, Bagella L, Dean C, Howard CM, Claudio PP, Baldi A, Khalili K, Giordano A.

J Biol Chem. 1997 Aug 22;272(34):20971-4.

47.

The retinoblastoma gene family pRb/p105, p107, pRb2/p130 and simian virus-40 large T-antigen in human mesotheliomas.

De Luca A, Baldi A, Esposito V, Howard CM, Bagella L, Rizzo P, Caputi M, Pass HI, Giordano GG, Baldi F, Carbone M, Giordano A.

Nat Med. 1997 Aug;3(8):913-6.

PMID:
9256285
48.
49.

cDNA sequences of three sheep myeloid cathelicidins.

Bagella L, Scocchi M, Zanetti M.

FEBS Lett. 1995 Dec 4;376(3):225-8.

50.

Molecular cloning, expression, and developmental characterization of the murine retinoblastoma-related gene Rb2/p130.

Pertile P, Baldi A, De Luca A, Bagella L, Virgilio L, Pisano MM, Giordano A.

Cell Growth Differ. 1995 Dec;6(12):1659-64.

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