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Items: 1 to 50 of 140

1.

Peroxisomal Disorders and Retinal Degeneration.

Das Y, Baes M.

Adv Exp Med Biol. 2019;1185:317-321. doi: 10.1007/978-3-030-27378-1_52.

PMID:
31884631
2.

Humoral immune responses and gill antioxidant-related gene expression of common carp (Cyprinus carpio) exposed to lufenuron and flonicamide.

Taheri Mirghaed A, Baes M, Hoseini SM.

Fish Physiol Biochem. 2019 Dec 17. doi: 10.1007/s10695-019-00747-x. [Epub ahead of print]

PMID:
31848827
3.

Liver disease predominates in a mouse model for mild human Zellweger spectrum disorder.

Berendse K, Boek M, Gijbels M, Van der Wel NN, Klouwer FC, van den Bergh-Weerman MA, Shinde AB, Ofman R, Poll-The BT, Houten SM, Baes M, Wanders RJA, Waterham HR.

Biochim Biophys Acta Mol Basis Dis. 2019 Oct 1;1865(10):2774-2787. doi: 10.1016/j.bbadis.2019.06.013. Epub 2019 Jun 15.

4.

Deciphering the potential involvement of PXMP2 and PEX11B in hydrogen peroxide permeation across the peroxisomal membrane reveals a role for PEX11B in protein sorting.

Lismont C, Koster J, Provost S, Baes M, Van Veldhoven PP, Waterham HR, Fransen M.

Biochim Biophys Acta Biomembr. 2019 Oct 1;1861(10):182991. doi: 10.1016/j.bbamem.2019.05.013. Epub 2019 May 24.

PMID:
31129117
5.

Wheat ms5 male-sterility is induced by recessive homoeologous A and D genome non-specific lipid transfer proteins.

Pallotta MA, Warner P, Kouidri A, Tucker EJ, Baes M, Suchecki R, Watson-Haigh N, Okada T, Garcia M, Sandhu A, Singh M, Wolters P, Albertsen MC, Cigan AM, Baumann U, Whitford R.

Plant J. 2019 Aug;99(4):673-685. doi: 10.1111/tpj.14350. Epub 2019 Jun 21.

PMID:
31009129
6.

Effects of Rht-B1 and Ppd-D1 loci on pollinator traits in wheat.

Okada T, Jayasinghe JEARM, Eckermann P, Watson-Haigh NS, Warner P, Hendrikse Y, Baes M, Tucker EJ, Laga H, Kato K, Albertsen M, Wolters P, Fleury D, Baumann U, Whitford R.

Theor Appl Genet. 2019 Jul;132(7):1965-1979. doi: 10.1007/s00122-019-03329-w. Epub 2019 Mar 21.

PMID:
30899967
7.

Microglia lacking a peroxisomal β-oxidation enzyme chronically alter their inflammatory profile without evoking neuronal and behavioral deficits.

Beckers L, Geric I, Stroobants S, Beel S, Van Damme P, D'Hooge R, Baes M.

J Neuroinflammation. 2019 Mar 13;16(1):61. doi: 10.1186/s12974-019-1442-3.

8.

Functional peroxisomes are required for β-cell integrity in mice.

Baboota RK, Shinde AB, Lemaire K, Fransen M, Vinckier S, Van Veldhoven PP, Schuit F, Baes M.

Mol Metab. 2019 Apr;22:71-83. doi: 10.1016/j.molmet.2019.02.001. Epub 2019 Feb 8.

9.

Differential distribution of peroxisomal proteins points to specific roles of peroxisomes in the murine retina.

Das Y, Roose N, De Groef L, Fransen M, Moons L, Van Veldhoven PP, Baes M.

Mol Cell Biochem. 2019 Jun;456(1-2):53-62. doi: 10.1007/s11010-018-3489-3. Epub 2019 Jan 2.

PMID:
30604065
10.

Peroxisomes can oxidize medium- and long-chain fatty acids through a pathway involving ABCD3 and HSD17B4.

Violante S, Achetib N, van Roermund CWT, Hagen J, Dodatko T, Vaz FM, Waterham HR, Chen H, Baes M, Yu C, Argmann CA, Houten SM.

FASEB J. 2019 Mar;33(3):4355-4364. doi: 10.1096/fj.201801498R. Epub 2018 Dec 12.

PMID:
30540494
11.

Wheat TaMs1 is a glycosylphosphatidylinositol-anchored lipid transfer protein necessary for pollen development.

Kouidri A, Baumann U, Okada T, Baes M, Tucker EJ, Whitford R.

BMC Plant Biol. 2018 Dec 5;18(1):332. doi: 10.1186/s12870-018-1557-1.

12.

Constitutive IP3 signaling underlies the sensitivity of B-cell cancers to the Bcl-2/IP3 receptor disruptor BIRD-2.

Bittremieux M, La Rovere RM, Akl H, Martines C, Welkenhuyzen K, Dubron K, Baes M, Janssens A, Vandenberghe P, Laurenti L, Rietdorf K, Morciano G, Pinton P, Mikoshiba K, Bootman MD, Efremov DG, De Smedt H, Parys JB, Bultynck G.

Cell Death Differ. 2019 Mar;26(3):531-547. doi: 10.1038/s41418-018-0142-3. Epub 2018 Jun 13.

13.

Neuronal Dysfunction and Behavioral Abnormalities Are Evoked by Neural Cells and Aggravated by Inflammatory Microglia in Peroxisomal β-Oxidation Deficiency.

Beckers L, Stroobants S, D'Hooge R, Baes M.

Front Cell Neurosci. 2018 May 23;12:136. doi: 10.3389/fncel.2018.00136. eCollection 2018.

14.
15.

Autonomous Purkinje cell axonal dystrophy causes ataxia in peroxisomal multifunctional protein-2 deficiency.

De Munter S, Bamps D, Malheiro AR, Kumar Baboota R, Brites P, Baes M.

Brain Pathol. 2018 Sep;28(5):631-643. doi: 10.1111/bpa.12586. Epub 2018 Feb 21.

PMID:
29341299
16.

Unfertilized ovary pushes wheat flower open for cross-pollination.

Okada T, Jayasinghe JEARM, Nansamba M, Baes M, Warner P, Kouidri A, Correia D, Nguyen V, Whitford R, Baumann U.

J Exp Bot. 2018 Jan 23;69(3):399-412. doi: 10.1093/jxb/erx410.

17.

Molecular identification of the wheat male fertility gene Ms1 and its prospects for hybrid breeding.

Tucker EJ, Baumann U, Kouidri A, Suchecki R, Baes M, Garcia M, Okada T, Dong C, Wu Y, Sandhu A, Singh M, Langridge P, Wolters P, Albertsen MC, Cigan AM, Whitford R.

Nat Commun. 2017 Oct 11;8(1):869. doi: 10.1038/s41467-017-00945-2.

18.

Lipid homeostasis and inflammatory activation are disturbed in classically activated macrophages with peroxisomal β-oxidation deficiency.

Geric I, Tyurina YY, Krysko O, Krysko DV, De Schryver E, Kagan VE, Van Veldhoven PP, Baes M, Verheijden S.

Immunology. 2018 Mar;153(3):342-356. doi: 10.1111/imm.12844. Epub 2017 Oct 26.

19.

Mitochondrial disruption in peroxisome deficient cells is hepatocyte selective but is not mediated by common hepatic peroxisomal metabolites.

Shinde AB, Baboota RK, Denis S, Loizides-Mangold U, Peeters A, Espeel M, Malheiro AR, Riezman H, Vinckier S, Vaz FM, Brites P, Ferdinandusse S, Van Veldhoven PP, Baes M.

Mitochondrion. 2018 Mar;39:51-59. doi: 10.1016/j.mito.2017.08.013. Epub 2017 Sep 1.

PMID:
28866057
20.

Increased Expression of Translocator Protein (TSPO) Marks Pro-inflammatory Microglia but Does Not Predict Neurodegeneration.

Beckers L, Ory D, Geric I, Declercq L, Koole M, Kassiou M, Bormans G, Baes M.

Mol Imaging Biol. 2018 Feb;20(1):94-102. doi: 10.1007/s11307-017-1099-1.

PMID:
28695372
21.

Peroxisomal biogenesis is genetically and biochemically linked to carbohydrate metabolism in Drosophila and mouse.

Wangler MF, Chao YH, Bayat V, Giagtzoglou N, Shinde AB, Putluri N, Coarfa C, Donti T, Graham BH, Faust JE, McNew JA, Moser A, Sardiello M, Baes M, Bellen HJ.

PLoS Genet. 2017 Jun 22;13(6):e1006825. doi: 10.1371/journal.pgen.1006825. eCollection 2017 Jun.

22.

Endothelial cell metabolism in health and disease: impact of hypoxia.

Wong BW, Marsch E, Treps L, Baes M, Carmeliet P.

EMBO J. 2017 Aug 1;36(15):2187-2203. doi: 10.15252/embj.201696150. Epub 2017 Jun 21. Review.

23.

Phytol-induced pathology in 2-hydroxyacyl-CoA lyase (HACL1) deficient mice. Evidence for a second non-HACL1-related lyase.

Mezzar S, De Schryver E, Asselberghs S, Meyhi E, Morvay PL, Baes M, Van Veldhoven PP.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Sep;1862(9):972-990. doi: 10.1016/j.bbalip.2017.06.004. Epub 2017 Jun 17.

PMID:
28629946
24.

Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy.

Kleinecke S, Richert S, de Hoz L, Brügger B, Kungl T, Asadollahi E, Quintes S, Blanz J, McGonigal R, Naseri K, Sereda MW, Sachsenheimer T, Lüchtenborg C, Möbius W, Willison H, Baes M, Nave KA, Kassmann CM.

Elife. 2017 May 4;6. pii: e23332. doi: 10.7554/eLife.23332.

25.

Differential activities of peroxisomes along the mouse intestinal epithelium.

Morvay PL, Baes M, Van Veldhoven PP.

Cell Biochem Funct. 2017 Apr;35(3):144-155. doi: 10.1002/cbf.3255. Epub 2017 Mar 29.

PMID:
28370438
26.

Inter-Subject Variability in OCT1 Activity in 27 Batches of Cryopreserved Human Hepatocytes and Association with OCT1 mRNA Expression and Genotype.

Fattah S, Shinde AB, Matic M, Baes M, van Schaik RHN, Allegaert K, Parmentier C, Richert L, Augustijns P, Annaert P.

Pharm Res. 2017 Jun;34(6):1309-1319. doi: 10.1007/s11095-017-2148-9. Epub 2017 Mar 31.

PMID:
28364304
27.

Specific suppression of microgliosis cannot circumvent the severe neuropathology in peroxisomal β-oxidation-deficient mice.

Beckers L, Stroobants S, Verheijden S, West B, D'Hooge R, Baes M.

Mol Cell Neurosci. 2017 Apr;80:123-133. doi: 10.1016/j.mcn.2017.03.004. Epub 2017 Mar 7.

PMID:
28286294
28.

Early-onset Purkinje cell dysfunction underlies cerebellar ataxia in peroxisomal multifunctional protein-2 deficiency.

De Munter S, Verheijden S, Vanderstuyft E, Malheiro AR, Brites P, Gall D, Schiffmann SN, Baes M.

Neurobiol Dis. 2016 Oct;94:157-68. doi: 10.1016/j.nbd.2016.06.012. Epub 2016 Jun 25.

PMID:
27353294
29.

Prolyl hydroxylase-1 regulates hepatocyte apoptosis in an NF-κB-dependent manner.

Fitzpatrick SF, Fábián Z, Schaible B, Lenihan CR, Schwarzl T, Rodriguez J, Zheng X, Li Z, Tambuwala MM, Higgins DG, O'Meara Y, Slattery C, Manresa MC, Fraisl P, Bruning U, Baes M, Carmeliet P, Doherty G, von Kriegsheim A, Cummins EP, Taylor CT.

Biochem Biophys Res Commun. 2016 Jun 3;474(3):579-586. doi: 10.1016/j.bbrc.2016.04.085. Epub 2016 Apr 27.

30.

Brief Report: The Deletion of the Phosphatase Regulator NIPP1 Causes Progenitor Cell Expansion in the Adult Liver.

Boens S, Verbinnen I, Verhulst S, Szekér K, Ferreira M, Gevaert T, Baes M, Roskams T, van Grunsven LA, Van Eynde A, Bollen M.

Stem Cells. 2016 Aug;34(8):2256-62. doi: 10.1002/stem.2375. Epub 2016 Jun 20.

31.

Optic neuritis, the most common initial presenting manifestation of multiple sclerosis in northern Iran.

Hojjati SM, Zarghami A, Hojjati SA, Baes M.

Caspian J Intern Med. 2015 Summer;6(3):151-5.

32.

Plate tectonics on the Earth triggered by plume-induced subduction initiation.

Gerya TV, Stern RJ, Baes M, Sobolev SV, Whattam SA.

Nature. 2015 Nov 12;527(7577):221-5. doi: 10.1038/nature15752.

PMID:
26560300
33.

Hepatic dysfunction in peroxisomal disorders.

Baes M, Van Veldhoven PP.

Biochim Biophys Acta. 2016 May;1863(5):956-70. doi: 10.1016/j.bbamcr.2015.09.035. Epub 2015 Oct 9. Review.

34.

Phytol is lethal for Amacr-deficient mice.

Selkälä EM, Nair RR, Schmitz W, Kvist AP, Baes M, Hiltunen JK, Autio KJ.

Biochim Biophys Acta. 2015 Oct;1851(10):1394-405. doi: 10.1016/j.bbalip.2015.07.008. Epub 2015 Aug 4.

PMID:
26248199
35.

Corrigendum: Fatty acid carbon is essential for dNTP synthesis in endothelial cells.

Schoors S, Bruning U, Missiaen R, Queiroz KC, Borgers G, Elia I, Zecchin A, Cantelmo AR, Christen S, Goveia J, Heggermont W, Goddë L, Vinckier S, Van Veldhoven PP, Eelen G, Schoonjans L, Gerhardt H, Dewerchin M, Baes M, De Bock K, Ghesquière B, Lunt SY, Fendt SM, Carmeliet P.

Nature. 2015 Oct 1;526(7571):144. doi: 10.1038/nature14624. Epub 2015 Aug 5. No abstract available.

PMID:
26245368
36.

Peroxisomal Disorders: A Review on Cerebellar Pathologies.

De Munter S, Verheijden S, Régal L, Baes M.

Brain Pathol. 2015 Nov;25(6):663-78. doi: 10.1111/bpa.12290. Epub 2015 Aug 19. Review.

PMID:
26201894
37.

Precise Anatomic Localization of Accumulated Lipids in Mfp2 Deficient Murine Brains Through Automated Registration of SIMS Images to the Allen Brain Atlas.

Škrášková K, Khmelinskii A, Abdelmoula WM, De Munter S, Baes M, McDonnell L, Dijkstra J, Heeren RM.

J Am Soc Mass Spectrom. 2015 Jun;26(6):948-57. doi: 10.1007/s13361-015-1146-6. Epub 2015 Apr 28.

38.

Identification of a chronic non-neurodegenerative microglia activation state in a mouse model of peroxisomal β-oxidation deficiency.

Verheijden S, Beckers L, Casazza A, Butovsky O, Mazzone M, Baes M.

Glia. 2015 Sep;63(9):1606-20. doi: 10.1002/glia.22831. Epub 2015 Apr 2.

39.

Fatty acid carbon is essential for dNTP synthesis in endothelial cells.

Schoors S, Bruning U, Missiaen R, Queiroz KC, Borgers G, Elia I, Zecchin A, Cantelmo AR, Christen S, Goveia J, Heggermont W, Goddé L, Vinckier S, Van Veldhoven PP, Eelen G, Schoonjans L, Gerhardt H, Dewerchin M, Baes M, De Bock K, Ghesquière B, Lunt SY, Fendt SM, Carmeliet P.

Nature. 2015 Apr 9;520(7546):192-197. doi: 10.1038/nature14362. Epub 2015 Apr 1. Erratum in: Nature. 2015 Oct 1;526(7571):144.

40.

Abl1 inhibitory contaminants leach from plastic tubes.

Chen H, Blanchaert B, Shinde AB, Adams E, Rozenski J, Baes M, Van Schepdael A.

J Enzyme Inhib Med Chem. 2016;31(2):340-3. doi: 10.3109/14756366.2015.1022171. Epub 2015 Mar 23.

PMID:
25798691
41.

The oxysterol and cholestenoic acid profile of mouse cerebrospinal fluid.

Crick PJ, Beckers L, Baes M, Van Veldhoven PP, Wang Y, Griffiths WJ.

Steroids. 2015 Jul;99(Pt B):172-7. doi: 10.1016/j.steroids.2015.02.021. Epub 2015 Mar 7.

42.

Mitochondria in peroxisome-deficient hepatocytes exhibit impaired respiration, depleted DNA, and PGC-1α independent proliferation.

Peeters A, Shinde AB, Dirkx R, Smet J, De Bock K, Espeel M, Vanhorebeek I, Vanlander A, Van Coster R, Carmeliet P, Fransen M, Van Veldhoven PP, Baes M.

Biochim Biophys Acta. 2015 Feb;1853(2):285-98. doi: 10.1016/j.bbamcr.2014.11.017. Epub 2014 Nov 20.

43.

Vaginal expression of efflux transporters and the potential impact on the disposition of microbicides in vitro and in rabbits.

Grammen C, Baes M, Haenen S, Verguts J, Augustyns K, Zydowsky T, La Colla P, Augustijns P, Brouwers J.

Mol Pharm. 2014 Dec 1;11(12):4405-14. doi: 10.1021/mp5005004. Epub 2014 Nov 4.

PMID:
25327902
44.

Role of AMACR (α-methylacyl-CoA racemase) and MFE-1 (peroxisomal multifunctional enzyme-1) in bile acid synthesis in mice.

Autio KJ, Schmitz W, Nair RR, Selkälä EM, Sormunen RT, Miinalainen IJ, Crick PJ, Wang Y, Griffiths WJ, Reddy JK, Baes M, Hiltunen JK.

Biochem J. 2014 Jul 1;461(1):125-35. doi: 10.1042/BJ20130915.

PMID:
24735479
45.
46.

Peroxisome deficient invertebrate and vertebrate animal models.

Van Veldhoven PP, Baes M.

Front Physiol. 2013 Nov 22;4:335. doi: 10.3389/fphys.2013.00335. Review.

47.

Mitochondria are targets for peroxisome-derived oxidative stress in cultured mammalian cells.

Wang B, Van Veldhoven PP, Brees C, Rubio N, Nordgren M, Apanasets O, Kunze M, Baes M, Agostinis P, Fransen M.

Free Radic Biol Med. 2013 Dec;65:882-894. doi: 10.1016/j.freeradbiomed.2013.08.173. Epub 2013 Aug 27.

PMID:
23988789
48.

Central nervous system pathology in MFP2 deficiency: insights from general and conditional knockout mouse models.

Verheijden S, Beckers L, De Munter S, Van Veldhoven PP, Baes M.

Biochimie. 2014 Mar;98:119-26. doi: 10.1016/j.biochi.2013.08.009. Epub 2013 Aug 19. Review.

PMID:
23969159
49.

Peroxisomal multifunctional protein-2 deficiency causes neuroinflammation and degeneration of Purkinje cells independent of very long chain fatty acid accumulation.

Verheijden S, Bottelbergs A, Krysko O, Krysko DV, Beckers L, De Munter S, Van Veldhoven PP, Wyns S, Kulik W, Nave KA, Ramer MS, Carmeliet P, Kassmann CM, Baes M.

Neurobiol Dis. 2013 Oct;58:258-69. doi: 10.1016/j.nbd.2013.06.006. Epub 2013 Jun 15.

PMID:
23777740
50.

Block of a subset of sodium channels exacerbates experimental autoimmune encephalomyelitis.

Stevens M, Timmermans S, Bottelbergs A, Hendriks JJ, Brône B, Baes M, Tytgat J.

J Neuroimmunol. 2013 Aug 15;261(1-2):21-8. doi: 10.1016/j.jneuroim.2013.04.012. Epub 2013 Jun 2.

PMID:
23735284

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