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Items: 1 to 50 of 114

1.

A screening-based approach identifies cell cycle regulators AURKA, CHK1 and PLK1 as targetable regulators of chondrosarcoma cell survival.

de Jong Y, Bennani F, van Oosterwijk JG, Alberti G, Baranski Z, Wijers-Koster P, Venneker S, Briaire-de Bruij IH, van de Akker BE, Baelde H, Cleton-Jansen AM, van de Water B, Danen EHJ, Bovée JVMG.

J Bone Oncol. 2019 Nov 17;19:100268. doi: 10.1016/j.jbo.2019.100268. eCollection 2019 Dec.

2.

Selective ETA versus dual ETA/B receptor blockade for the prevention of sunitinib-induced hypertension and albuminuria in WKY rats.

Mirabito Colafella KM, Neves KB, Montezano AC, Garrelds IM, van Veghel R, de Vries R, Uijl E, Baelde HJ, van den Meiracker AH, Touyz RM, Danser AHJ, Versmissen J.

Cardiovasc Res. 2019 Oct 8. pii: cvz260. doi: 10.1093/cvr/cvz260. [Epub ahead of print]

PMID:
31593221
3.

Glomerular permeability is not affected by heparan sulfate glycosaminoglycan deficiency in zebrafish embryos.

Khalil R, Lalai RA, Wiweger MI, Avramut CM, Koster AJ, Spaink HP, Bruijn JA, Hogendoorn PCW, Baelde HJ.

Am J Physiol Renal Physiol. 2019 Nov 1;317(5):F1211-F1216. doi: 10.1152/ajprenal.00126.2019. Epub 2019 Aug 28.

PMID:
31461353
4.

The Vascular Endothelial Growth Factor Inhibitor Soluble FLT-1 Ameliorates Atopic Dermatitis in APOC1 Transgenic Mice.

van Aanhold CCL, Bus P, Zandbergen M, Bos M, Berbée JFP, Quint KD, Bruijn JA, Baelde HJ.

J Invest Dermatol. 2020 Feb;140(2):491-494.e4. doi: 10.1016/j.jid.2019.07.700. Epub 2019 Aug 16. No abstract available.

PMID:
31425708
5.

Complement-mediated microangiopathy in IgA nephropathy and IgA vasculitis with nephritis.

Chua JS, Zandbergen M, Wolterbeek R, Baelde HJ, van Es LA, de Fijter JW, Bruijn JA, Bajema IM.

Mod Pathol. 2019 Jul;32(8):1147-1157. doi: 10.1038/s41379-019-0259-z. Epub 2019 Apr 1.

PMID:
30936425
6.

Exploration of the chondrosarcoma metabolome; the mTOR pathway as an important pro-survival pathway.

Addie RD, de Jong Y, Alberti G, Kruisselbrink AB, Que I, Baelde H, Bovée JVMG.

J Bone Oncol. 2019 Jan 29;15:100222. doi: 10.1016/j.jbo.2019.100222. eCollection 2019 Apr.

7.

Increased dynamin expression precedes proteinuria in glomerular disease.

Khalil R, Koop K, Kreutz R, Spaink HP, Hogendoorn PC, Bruijn JA, Baelde HJ.

J Pathol. 2019 Feb;247(2):177-185. doi: 10.1002/path.5181. Epub 2018 Nov 27.

8.

Endoglin Mediates Vascular Endothelial Growth Factor-A-Induced Endothelial Cell Activation by Regulating Akt Signaling.

Bus P, Gerrits T, Heemskerk SAC, Zandbergen M, Wolterbeek R, Bruijn JA, Baelde HJ, Scharpfenecker M.

Am J Pathol. 2018 Dec;188(12):2924-2935. doi: 10.1016/j.ajpath.2018.08.005. Epub 2018 Sep 22.

9.

Protective Actions of Anserine Under Diabetic Conditions.

Peters V, Calabrese V, Forsberg E, Volk N, Fleming T, Baelde H, Weigand T, Thiel C, Trovato A, Scuto M, Modafferi S, Schmitt CP.

Int J Mol Sci. 2018 Sep 13;19(9). pii: E2751. doi: 10.3390/ijms19092751.

10.

Cumulative dose of bevacizumab associates with albuminuria rather than podocyturia in cancer patients.

Lankhorst S, Baelde HJ, Verstijnen JAMC, Ten Tije AJ, Thelen MHM, Danser AHJ, van den Meiracker AH, Kappers MHW.

J Am Soc Hypertens. 2018 Nov;12(11):e1-e7. doi: 10.1016/j.jash.2018.06.005. Epub 2018 Jun 18.

PMID:
29960864
11.

Complement Activation in Patients With Diabetic Nephropathy.

Bus P, Chua JS, Klessens CQF, Zandbergen M, Wolterbeek R, van Kooten C, Trouw LA, Bruijn JA, Baelde HJ.

Kidney Int Rep. 2017 Oct 16;3(2):302-313. doi: 10.1016/j.ekir.2017.10.005. eCollection 2018 Mar.

12.

Carnosine Catalyzes the Formation of the Oligo/Polymeric Products of Methylglyoxal.

Weigand T, Singler B, Fleming T, Nawroth P, Klika KD, Thiel C, Baelde H, Garbade SF, Wagner AH, Hecker M, Yard BA, Amberger A, Zschocke J, Schmitt CP, Peters V.

Cell Physiol Biochem. 2018;46(2):713-726. doi: 10.1159/000488727. Epub 2018 Mar 29.

13.

Diabetic Nephropathy: Novel Molecular Mechanisms and Therapeutic Avenues.

Oltean S, Coward R, Collino M, Baelde H.

Biomed Res Int. 2017;2017:3146524. doi: 10.1155/2017/3146524. Epub 2017 Nov 22. No abstract available.

14.

Towards standardized criteria for diagnosing chronic intervillositis of unknown etiology: A systematic review.

Bos M, Nikkels PGJ, Cohen D, Schoones JW, Bloemenkamp KWM, Bruijn JA, Baelde HJ, van der Hoorn MLP, Turner RJ.

Placenta. 2018 Jan;61:80-88. doi: 10.1016/j.placenta.2017.11.012. Epub 2017 Nov 23. Review.

15.

Metabolic imaging of fatty kidney in diabesity: validation and dietary intervention.

Jonker JT, de Heer P, Engelse MA, van Rossenberg EH, Klessens CQF, Baelde HJ, Bajema IM, Koopmans SJ, Coelho PG, Streefland TCM, Webb AG, Dekkers IA, Rabelink TJ, Rensen PCN, Lamb HJ, de Vries APJ.

Nephrol Dial Transplant. 2018 Feb 1;33(2):224-230. doi: 10.1093/ndt/gfx243.

PMID:
28992141
16.

The VEGF-A inhibitor sFLT-1 improves renal function by reducing endothelial activation and inflammation in a mouse model of type 1 diabetes.

Bus P, Scharpfenecker M, Van Der Wilk P, Wolterbeek R, Bruijn JA, Baelde HJ.

Diabetologia. 2017 Sep;60(9):1813-1821. doi: 10.1007/s00125-017-4322-3. Epub 2017 Jun 15.

17.

Carnosine Attenuates the Development of both Type 2 Diabetes and Diabetic Nephropathy in BTBR ob/ob Mice.

Albrecht T, Schilperoort M, Zhang S, Braun JD, Qiu J, Rodriguez A, Pastene DO, Krämer BK, Köppel H, Baelde H, de Heer E, Anna Altomare A, Regazzoni L, Denisi A, Aldini G, van den Born J, Yard BA, Hauske SJ.

Sci Rep. 2017 Mar 10;7:44492. doi: 10.1038/srep44492.

18.

Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction.

Elmonem MA, Khalil R, Khodaparast L, Khodaparast L, Arcolino FO, Morgan J, Pastore A, Tylzanowski P, Ny A, Lowe M, de Witte PA, Baelde HJ, van den Heuvel LP, Levtchenko E.

Sci Rep. 2017 Feb 15;7:42583. doi: 10.1038/srep42583.

19.

Apolipoprotein C-I plays a role in the pathogenesis of glomerulosclerosis.

Bus P, Pierneef L, Bor R, Wolterbeek R, van Es LA, Rensen PC, de Heer E, Havekes LM, Bruijn JA, Berbée JF, Baelde HJ.

J Pathol. 2017 Apr;241(5):589-599. doi: 10.1002/path.4859. Epub 2017 Feb 2.

PMID:
27976371
20.

Loss of placental thrombomodulin in oocyte donation pregnancies.

Bos M, Baelde HJ, Bruijn JA, Bloemenkamp KW, van der Hoorn MP, Turner RJ.

Fertil Steril. 2017 Jan;107(1):119-129.e5. doi: 10.1016/j.fertnstert.2016.10.005. Epub 2016 Oct 25.

PMID:
27793368
21.

Stability and Species Specificity of Renal VEGF-A Splicing Patterns in Kidney Disease.

Turner RJ, Eikmans M, Bajema IM, Bruijn JA, Baelde HJ.

PLoS One. 2016 Sep 6;11(9):e0162166. doi: 10.1371/journal.pone.0162166. eCollection 2016.

22.

Loss of Thrombomodulin in Placental Dysfunction in Preeclampsia.

Turner RJ, Bloemenkamp KW, Bruijn JA, Baelde HJ.

Arterioscler Thromb Vasc Biol. 2016 Apr;36(4):728-35. doi: 10.1161/ATVBAHA.115.306780. Epub 2016 Feb 18.

PMID:
26891741
23.

Effect of high salt diet on blood pressure and renal damage during vascular endothelial growth factor inhibition with sunitinib.

Lankhorst S, Baelde HJ, Clahsen-van Groningen MC, Smedts FM, Danser AH, van den Meiracker AH.

Nephrol Dial Transplant. 2016 Jun;31(6):914-21. doi: 10.1093/ndt/gfv410. Epub 2015 Dec 17.

PMID:
26681729
24.

Aerobic and resistance training do not influence plasma carnosinase content or activity in type 2 diabetes.

Stegen S, Sigal RJ, Kenny GP, Khandwala F, Yard B, De Heer E, Baelde H, Peersman W, Derave W.

Am J Physiol Endocrinol Metab. 2015 Oct 1;309(7):E663-9. doi: 10.1152/ajpendo.00142.2015. Epub 2015 Aug 4.

25.

Intrinsic carnosine metabolism in the human kidney.

Peters V, Klessens CQ, Baelde HJ, Singler B, Veraar KA, Zutinic A, Drozak J, Zschocke J, Schmitt CP, de Heer E.

Amino Acids. 2015 Dec;47(12):2541-50. doi: 10.1007/s00726-015-2045-7. Epub 2015 Jul 24.

26.

Greater Sensitivity of Blood Pressure Than Renal Toxicity to Tyrosine Kinase Receptor Inhibition With Sunitinib.

Lankhorst S, Baelde HJ, Kappers MH, Smedts FM, Hansen A, Clahsen-van Groningen MC, Sleijfer S, Mathijssen RH, Danser AH, van den Meiracker AH.

Hypertension. 2015 Sep;66(3):543-9. doi: 10.1161/HYPERTENSIONAHA.115.05435. Epub 2015 Jul 20.

PMID:
26195484
27.

From Glomerular Endothelium to Podocyte Pathobiology in Preeclampsia: a Paradigm Shift.

Turner RJ, Bloemenkamp KW, Penning ME, Bruijn JA, Baelde HJ.

Curr Hypertens Rep. 2015 Jul;17(7):54. doi: 10.1007/s11906-015-0566-9. Review.

PMID:
26068658
28.

The oncometabolite D-2-hydroxyglutarate induced by mutant IDH1 or -2 blocks osteoblast differentiation in vitro and in vivo.

Suijker J, Baelde HJ, Roelofs H, Cleton-Jansen AM, Bovée JV.

Oncotarget. 2015 Jun 20;6(17):14832-42.

29.

UPF0586 Protein C9orf41 Homolog Is Anserine-producing Methyltransferase.

Drozak J, Piecuch M, Poleszak O, Kozlowski P, Chrobok L, Baelde HJ, de Heer E.

J Biol Chem. 2015 Jul 10;290(28):17190-205. doi: 10.1074/jbc.M115.640037. Epub 2015 May 22.

30.

Classical Complement Pathway Activation in the Kidneys of Women With Preeclampsia.

Penning M, Chua JS, van Kooten C, Zandbergen M, Buurma A, Schutte J, Bruijn JA, Khankin EV, Bloemenkamp K, Karumanchi SA, Baelde H.

Hypertension. 2015 Jul;66(1):117-25. doi: 10.1161/HYPERTENSIONAHA.115.05484. Epub 2015 May 4.

31.

Early systemic microvascular damage in pigs with atherogenic diabetes mellitus coincides with renal angiopoietin dysbalance.

Khairoun M, van den Heuvel M, van den Berg BM, Sorop O, de Boer R, van Ditzhuijzen NS, Bajema IM, Baelde HJ, Zandbergen M, Duncker DJ, Rabelink TJ, Reinders ME, van der Giessen WJ, Rotmans JI.

PLoS One. 2015 Apr 24;10(4):e0121555. doi: 10.1371/journal.pone.0121555. eCollection 2015.

32.

Complement Factor C4d Is a Common Denominator in Thrombotic Microangiopathy.

Chua JS, Baelde HJ, Zandbergen M, Wilhelmus S, van Es LA, de Fijter JW, Bruijn JA, Bajema IM, Cohen D.

J Am Soc Nephrol. 2015 Sep;26(9):2239-47. doi: 10.1681/ASN.2014050429. Epub 2015 Jan 8.

33.

Vascular Endothelial Growth Factor-A165b Is Protective and Restores Endothelial Glycocalyx in Diabetic Nephropathy.

Oltean S, Qiu Y, Ferguson JK, Stevens M, Neal C, Russell A, Kaura A, Arkill KP, Harris K, Symonds C, Lacey K, Wijeyaratne L, Gammons M, Wylie E, Hulse RP, Alsop C, Cope G, Damodaran G, Betteridge KB, Ramnath R, Satchell SC, Foster RR, Ballmer-Hofer K, Donaldson LF, Barratt J, Baelde HJ, Harper SJ, Bates DO, Salmon AH.

J Am Soc Nephrol. 2015 Aug;26(8):1889-904. doi: 10.1681/ASN.2014040350. Epub 2014 Dec 26.

34.

Treatment of hypertension and renal injury induced by the angiogenesis inhibitor sunitinib: preclinical study.

Lankhorst S, Kappers MH, van Esch JH, Smedts FM, Sleijfer S, Mathijssen RH, Baelde HJ, Danser AH, van den Meiracker AH.

Hypertension. 2014 Dec;64(6):1282-9. doi: 10.1161/HYPERTENSIONAHA.114.04187. Epub 2014 Sep 2.

PMID:
25185126
35.

Association of preeclampsia with podocyte turnover.

Penning ME, Bloemenkamp KW, van der Zon T, Zandbergen M, Schutte JM, Bruijn JA, Bajema IM, Baelde HJ.

Clin J Am Soc Nephrol. 2014 Aug 7;9(8):1377-85. doi: 10.2215/CJN.12811213. Epub 2014 Jul 17.

36.

Genetic variants in pre-eclampsia should be interpreted with caution.

Buurma AJ, Dekkers OM, Baelde HJ.

Hum Reprod Update. 2013 Jul-Aug;19(4):428-9. No abstract available.

PMID:
23930269
37.

In vivo imaging of disease-modified glomerular extracellular matrix in renal disease.

Baelde H, de Heer E.

Kidney Int. 2013 Aug;84(2):238-9. doi: 10.1038/ki.2013.123.

38.

Preeclampsia is associated with the presence of transcriptionally active placental fragments in the maternal lung.

Buurma AJ, Penning ME, Prins F, Schutte JM, Bruijn JA, Wilhelmus S, Rajakumar A, Bloemenkamp KW, Karumanchi SA, Baelde HJ.

Hypertension. 2013 Sep;62(3):608-13. doi: 10.1161/HYPERTENSIONAHA.113.01505. Epub 2013 Jul 1.

PMID:
23817495
39.

PP034. Renal histology in preeclampsia: A special role for the podocyte.

Penning M, Bloemenkamp K, Schutte J, Bruijn JA, Bajema I, Baelde H.

Pregnancy Hypertens. 2013 Apr;3(2):79. doi: 10.1016/j.preghy.2013.04.061. Epub 2013 Jun 6.

PMID:
26105891
40.

Genetic variants in pre-eclampsia: a meta-analysis.

Buurma AJ, Turner RJ, Driessen JH, Mooyaart AL, Schoones JW, Bruijn JA, Bloemenkamp KW, Dekkers OM, Baelde HJ.

Hum Reprod Update. 2013 May-Jun;19(3):289-303. doi: 10.1093/humupd/dms060. Epub 2013 Jan 8.

PMID:
23300202
41.

Ambrisentan reduces pulmonary arterial hypertension but does not stimulate alveolar and vascular development in neonatal rats with hyperoxic lung injury.

Wagenaar GT, Laghmani el H, de Visser YP, Sengers RM, Steendijk P, Baelde HJ, Walther FJ.

Am J Physiol Lung Cell Mol Physiol. 2013 Feb 15;304(4):L264-75. doi: 10.1152/ajplung.00073.2012. Epub 2013 Jan 4.

42.

Vegfa protects the glomerular microvasculature in diabetes.

Sivaskandarajah GA, Jeansson M, Maezawa Y, Eremina V, Baelde HJ, Quaggin SE.

Diabetes. 2012 Nov;61(11):2958-66. doi: 10.2337/db11-1655.

43.

Quantitative polymerase chain reaction-based analysis of podocyturia is a feasible diagnostic tool in preeclampsia.

Kelder TP, Penning ME, Uh HW, Cohen D, Bloemenkamp KW, Bruijn JA, Scherjon SA, Baelde HJ.

Hypertension. 2012 Dec;60(6):1538-44. doi: 10.1161/HYPERTENSIONAHA.112.201681. Epub 2012 Oct 22.

PMID:
23090771
44.

Involvement of the tubular ClC-type exchanger ClC-5 in glomeruli of human proteinuric nephropathies.

Ceol M, Tiralongo E, Baelde HJ, Vianello D, Betto G, Marangelli A, Bonfante L, Valente M, Della Barbera M, D'Angelo A, Anglani F, Del Prete D.

PLoS One. 2012;7(9):e45605. doi: 10.1371/journal.pone.0045605. Epub 2012 Sep 24.

45.

Preeclampsia is characterized by placental complement dysregulation.

Buurma A, Cohen D, Veraar K, Schonkeren D, Claas FH, Bruijn JA, Bloemenkamp KW, Baelde HJ.

Hypertension. 2012 Nov;60(5):1332-7. doi: 10.1161/HYPERTENSIONAHA.112.194324. Epub 2012 Sep 24.

PMID:
23006730
46.

OS092. qPCR-based analysis of podocyturia is a feasible diagnostic tool in preeclampsia.

Penning M, Kelder T, Uh HW, Cohen D, Scherjon S, Bruijn JA, Bloemenkamp K, Baelde H.

Pregnancy Hypertens. 2012 Jul;2(3):228. doi: 10.1016/j.preghy.2012.04.093. Epub 2012 Jun 13.

PMID:
26105306
47.

OS050. Genetic variants in pre-eclampsia: a meta-analysis.

Buurma A, Turner R, Driessen A, Mooyaart A, Schoones J, Bruijn JA, Bloemenkamp K, Baelde H.

Pregnancy Hypertens. 2012 Jul;2(3):204. doi: 10.1016/j.preghy.2012.04.051. Epub 2012 Jun 13.

PMID:
26105264
48.

Paratesticular desmoplastic small round cell tumour: an unusual tumour with an unusual fusion; cytogenetic and molecular genetic analysis combining RT-PCR and COBRA-FISH.

Cliteur VP, Szuhai K, Baelde HJ, van Dam J, Gelderblom H, Hogendoorn PC.

Clin Sarcoma Res. 2012 Jan 25;2(1):3. doi: 10.1186/2045-3329-2-3.

49.

Low plasma carnosinase activity promotes carnosinemia after carnosine ingestion in humans.

Everaert I, Taes Y, De Heer E, Baelde H, Zutinic A, Yard B, Sauerhöfer S, Vanhee L, Delanghe J, Aldini G, Derave W.

Am J Physiol Renal Physiol. 2012 Jun 15;302(12):F1537-44. doi: 10.1152/ajprenal.00084.2012. Epub 2012 Apr 11.

50.

CYP3A5 genotype-phenotype analysis in the human kidney reveals a strong site-specific expression of CYP3A5 in the proximal tubule in carriers of the CYP3A5*1 allele.

Bolbrinker J, Seeberg S, Schostak M, Kempkensteffen C, Baelde H, de Heer E, Kreutz R.

Drug Metab Dispos. 2012 Apr;40(4):639-41. doi: 10.1124/dmd.111.042648. Epub 2012 Jan 3.

PMID:
22214815

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