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Items: 47

1.

The use of Drosophila melanogaster as a model organism to study immune-nanotoxicity.

Ng CT, Yu LE, Ong CN, Bay BH, Baeg GH.

Nanotoxicology. 2019 May;13(4):429-446. doi: 10.1080/17435390.2018.1546413. Epub 2018 Nov 19.

PMID:
30451554
2.

Characterization and ecotoxicological investigation of biochar produced via slow pyrolysis: Effect of feedstock composition and pyrolysis conditions.

Yang X, Ng W, Wong BSE, Baeg GH, Wang CH, Ok YS.

J Hazard Mater. 2019 Mar 5;365:178-185. doi: 10.1016/j.jhazmat.2018.10.047. Epub 2018 Oct 28.

PMID:
30439617
3.

Y-box binding protein-1 and STAT3 independently regulate ATP-binding cassette transporters in the chemoresistance of gastric cancer cells.

Chua PJ, Lim JP, Guo TT, Khanna P, Hu Q, Bay BH, Baeg GH.

Int J Oncol. 2018 Dec;53(6):2579-2589. doi: 10.3892/ijo.2018.4557. Epub 2018 Sep 11.

PMID:
30221675
4.

GRAMD1B regulates cell migration in breast cancer cells through JAK/STAT and Akt signaling.

Khanna P, Lee JS, Sereemaspun A, Lee H, Baeg GH.

Sci Rep. 2018 Jun 22;8(1):9511. doi: 10.1038/s41598-018-27864-6.

5.

Evaluation of sewage sludge incineration ash as a potential land reclamation material.

Lin WY, Ng WC, Wong BSE, Teo SL, Sivananthan GD, Baeg GH, Ok YS, Wang CH.

J Hazard Mater. 2018 Sep 5;357:63-72. doi: 10.1016/j.jhazmat.2018.05.047. Epub 2018 May 23.

PMID:
29864689
6.

Oxidative stress promotes exit from the stem cell state and spontaneous neuronal differentiation.

Hu Q, Khanna P, Ee Wong BS, Lin Heng ZS, Subhramanyam CS, Thanga LZ, Sing Tan SW, Baeg GH.

Oncotarget. 2017 Dec 30;9(3):4223-4238. doi: 10.18632/oncotarget.23786. eCollection 2018 Jan 9.

7.

GRAM domain-containing protein 1B (GRAMD1B), a novel component of the JAK/STAT signaling pathway, functions in gastric carcinogenesis.

Khanna P, Chua PJ, Wong BSE, Yin C, Thike AA, Wan WK, Tan PH, Baeg GH.

Oncotarget. 2017 Dec 15;8(70):115370-115383. doi: 10.18632/oncotarget.23265. eCollection 2017 Dec 29.

8.

Small Maf functions in the maintenance of germline stem cells in the Drosophila testis.

Tan SWS, Yip GW, Suda T, Baeg GH.

Redox Biol. 2018 May;15:125-134. doi: 10.1016/j.redox.2017.12.002. Epub 2017 Dec 8.

9.

Potential adverse effects of engineered nanomaterials commonly used in food on the miRNome.

Lim JP, Baeg GH, Srinivasan DK, Dheen ST, Bay BH.

Food Chem Toxicol. 2017 Nov;109(Pt 1):771-779. doi: 10.1016/j.fct.2017.07.030. Epub 2017 Jul 15. Review.

PMID:
28720288
10.

Role of epigenome in tumorigenesis and drug resistance.

Hu Q, Baeg GH.

Food Chem Toxicol. 2017 Nov;109(Pt 1):663-668. doi: 10.1016/j.fct.2017.07.022. Epub 2017 Jul 11. Review.

PMID:
28709969
11.

Epigenetic modulations in nanoparticle-mediated toxicity.

Wong BSE, Hu Q, Baeg GH.

Food Chem Toxicol. 2017 Nov;109(Pt 1):746-752. doi: 10.1016/j.fct.2017.07.006. Epub 2017 Jul 5. Review.

PMID:
28689059
12.

Redox Homeostasis Plays Important Roles in the Maintenance of the Drosophila Testis Germline Stem Cells.

Tan SWS, Lee QY, Wong BSE, Cai Y, Baeg GH.

Stem Cell Reports. 2017 Jul 11;9(1):342-354. doi: 10.1016/j.stemcr.2017.05.034. Epub 2017 Jun 29.

13.

Biomedical Applications of Nanomaterials as Therapeutics.

Ng CT, Baeg GH, Yu LE, Ong CN, Bay BH.

Curr Med Chem. 2018;25(12):1409-1419. doi: 10.2174/0929867324666170331120328. Review.

PMID:
28393698
14.

Zinc oxide nanoparticles exhibit cytotoxicity and genotoxicity through oxidative stress responses in human lung fibroblasts and Drosophila melanogaster.

Ng CT, Yong LQ, Hande MP, Ong CN, Yu LE, Bay BH, Baeg GH.

Int J Nanomedicine. 2017 Feb 28;12:1621-1637. doi: 10.2147/IJN.S124403. eCollection 2017.

15.

Rapid toxicity screening of gasification ashes.

Zhen X, Rong L, Ng WC, Ong C, Baeg GH, Zhang W, Lee SN, Li SF, Dai Y, Tong YW, Neoh KG, Wang CH.

Waste Manag. 2016 Apr;50:93-104. doi: 10.1016/j.wasman.2016.02.016. Epub 2016 Feb 28.

PMID:
26923299
16.

Silver nanoparticles disrupt germline stem cell maintenance in the Drosophila testis.

Ong C, Lee QY, Cai Y, Liu X, Ding J, Yung LY, Bay BH, Baeg GH.

Sci Rep. 2016 Feb 5;6:20632. doi: 10.1038/srep20632.

17.

Coordinated niche-associated signals promote germline homeostasis in the Drosophila ovary.

Liu Z, Zhong G, Chai PC, Luo L, Liu S, Yang Y, Baeg GH, Cai Y.

J Cell Biol. 2015 Oct 26;211(2):469-84. doi: 10.1083/jcb.201503033.

18.

The JAK/STAT signaling cascade in gastric carcinoma (Review).

Khanna P, Chua PJ, Bay BH, Baeg GH.

Int J Oncol. 2015 Nov;47(5):1617-26. doi: 10.3892/ijo.2015.3160. Epub 2015 Sep 14. Review.

PMID:
26398764
19.

Nanotoxicity: An Interplay of Oxidative Stress, Inflammation and Cell Death.

Khanna P, Ong C, Bay BH, Baeg GH.

Nanomaterials (Basel). 2015 Jun 30;5(3):1163-1180. doi: 10.3390/nano5031163. Review.

20.

Windpipe controls Drosophila intestinal homeostasis by regulating JAK/STAT pathway via promoting receptor endocytosis and lysosomal degradation.

Ren W, Zhang Y, Li M, Wu L, Wang G, Baeg GH, You J, Li Z, Lin X.

PLoS Genet. 2015 Apr 29;11(4):e1005180. doi: 10.1371/journal.pgen.1005180. eCollection 2015 Apr.

21.

Clinicopathological significance of ARID1B in breast invasive ductal carcinoma.

Shao F, Guo T, Chua PJ, Tang L, Thike AA, Tan PH, Bay BH, Baeg GH.

Histopathology. 2015 Nov;67(5):709-18. doi: 10.1111/his.12701. Epub 2015 May 17.

PMID:
25817822
22.

Complement component 1, q subcomponent binding protein is a marker for proliferation in breast cancer.

Scully OJ, Yu Y, Salim A, Thike AA, Yip GW, Baeg GH, Tan PH, Matsumoto K, Bay BH.

Exp Biol Med (Maywood). 2015 Jul;240(7):846-53. doi: 10.1177/1535370214565075. Epub 2015 Jan 7.

23.

Y-box binding protein 1 is correlated with lymph node metastasis in intestinal-type gastric cancer.

Guo T, Yu Y, Yip GW, Baeg GH, Thike AA, Lim TK, Tan PH, Matsumoto K, Bay BH.

Histopathology. 2015 Mar;66(4):491-9. doi: 10.1111/his.12570. Epub 2014 Dec 23.

PMID:
25270600
24.

Identification of mutant alleles of JAK3 in pediatric patients with acute lymphoblastic leukemia.

Yin C, Sandoval C, Baeg GH.

Leuk Lymphoma. 2015 May;56(5):1502-6. doi: 10.3109/10428194.2014.957204. Epub 2015 Jan 21.

PMID:
25146434
25.

Drosophila melanogaster as a model organism to study nanotoxicity.

Ong C, Yung LY, Cai Y, Bay BH, Baeg GH.

Nanotoxicology. 2015 May;9(3):396-403. doi: 10.3109/17435390.2014.940405. Epub 2014 Jul 22. Review.

PMID:
25051331
26.

Benzoxathiol derivative BOT-4-one suppresses L540 lymphoma cell survival and proliferation via inhibition of JAK3/STAT3 signaling.

Kim BH, Min YS, Choi JS, Baeg GH, Kim YS, Shin JW, Kim TY, Ye SK.

Exp Mol Med. 2011 May 31;43(5):313-21. doi: 10.3858/emm.2011.43.2.035.

27.

Inhibition of the signalling kinase JAK3 alleviates inflammation in monoarthritic rats.

Kim BH, Kim M, Yin CH, Jee JG, Sandoval C, Lee H, Bach EA, Hahm DH, Baeg GH.

Br J Pharmacol. 2011 Sep;164(1):106-18. doi: 10.1111/j.1476-5381.2011.01353.x.

28.

Development of a high-throughput cell-based reporter assay for screening of JAK3 inhibitors.

Yin CH, Bach EA, Baeg GH.

J Biomol Screen. 2011 Apr;16(4):443-9. doi: 10.1177/1087057111400190. Epub 2011 Mar 10.

29.

NSC114792, a novel small molecule identified through structure-based computational database screening, selectively inhibits JAK3.

Kim BH, Jee JG, Yin CH, Sandoval C, Jayabose S, Kitamura D, Bach EA, Baeg GH.

Mol Cancer. 2010 Feb 11;9:36. doi: 10.1186/1476-4598-9-36.

30.

MS-1020 is a novel small molecule that selectively inhibits JAK3 activity.

Kim BH, Oh SR, Yin CH, Lee S, Kim EA, Kim MS, Sandoval C, Jayabose S, Bach EA, Lee HK, Baeg GH.

Br J Haematol. 2010 Jan;148(1):132-43. doi: 10.1111/j.1365-2141.2009.07925.x. Epub 2009 Sep 29.

31.

A small-molecule compound identified through a cell-based screening inhibits JAK/STAT pathway signaling in human cancer cells.

Kim BH, Yin CH, Guo Q, Bach EA, Lee H, Sandoval C, Jayabose S, Ulaczyk-Lesanko A, Hall DG, Baeg GH.

Mol Cancer Ther. 2008 Sep;7(9):2672-80. doi: 10.1158/1535-7163.MCT-08-0309.

32.

The JAK/STAT pathway regulates proximo-distal patterning in Drosophila.

Ayala-Camargo A, Ekas LA, Flaherty MS, Baeg GH, Bach EA.

Dev Dyn. 2007 Oct;236(10):2721-30.

33.

JAK/STAT signaling promotes regional specification by negatively regulating wingless expression in Drosophila.

Ekas LA, Baeg GH, Flaherty MS, Ayala-Camargo A, Bach EA.

Development. 2006 Dec;133(23):4721-9. Epub 2006 Nov 1.

34.

GFP reporters detect the activation of the Drosophila JAK/STAT pathway in vivo.

Bach EA, Ekas LA, Ayala-Camargo A, Flaherty MS, Lee H, Perrimon N, Baeg GH.

Gene Expr Patterns. 2007 Jan;7(3):323-31. Epub 2006 Aug 22.

PMID:
17008134
35.

Genome-wide RNAi analysis of JAK/STAT signaling components in Drosophila.

Baeg GH, Zhou R, Perrimon N.

Genes Dev. 2005 Aug 15;19(16):1861-70. Epub 2005 Jul 29.

36.

The Wingless morphogen gradient is established by the cooperative action of Frizzled and Heparan Sulfate Proteoglycan receptors.

Baeg GH, Selva EM, Goodman RM, Dasgupta R, Perrimon N.

Dev Biol. 2004 Dec 1;276(1):89-100.

37.

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism.

Liu C, Li Y, Semenov M, Han C, Baeg GH, Tan Y, Zhang Z, Lin X, He X.

Cell. 2002 Mar 22;108(6):837-47.

38.

Dual role of the fringe connection gene in both heparan sulphate and fringe-dependent signalling events.

Selva EM, Hong K, Baeg GH, Beverley SM, Turco SJ, Perrimon N, H├Ącker U.

Nat Cell Biol. 2001 Sep;3(9):809-15.

PMID:
11533660
39.

Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless.

Baeg GH, Lin X, Khare N, Baumgartner S, Perrimon N.

Development. 2001 Jan;128(1):87-94.

40.

Functional binding of secreted molecules to heparan sulfate proteoglycans in Drosophila.

Baeg GH, Perrimon N.

Curr Opin Cell Biol. 2000 Oct;12(5):575-80. Review.

PMID:
10978892
41.

Growth suppression of non-small cell lung carcinoma cells by the introduction of the p16(INK4A) gene.

Adachi J, Kohno T, Baeg G, Akiyama T, Yokota J.

Int J Oncol. 1997 Jan;10(1):33-9.

PMID:
21533340
42.

Suppression of fibroblast cell growth by overexpression of LIM-kinase 1.

Higuchi O, Baeg GH, Akiyama T, Mizuno K.

FEBS Lett. 1996 Oct 28;396(1):81-6.

43.

The tumor suppressor protein APC colocalizes with beta-catenin in the colon epithelial cells.

Senda T, Miyashiro I, Matsumine A, Baeg GH, Monden T, Kobayashil S, Monden M, Toyoshima K, Akiyama T.

Biochem Biophys Res Commun. 1996 Jun 14;223(2):329-34.

PMID:
8670282
44.

Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein.

Matsumine A, Ogai A, Senda T, Okumura N, Satoh K, Baeg GH, Kawahara T, Kobayashi S, Okada M, Toyoshima K, Akiyama T.

Science. 1996 May 17;272(5264):1020-3.

PMID:
8638125
45.

MCC, a cytoplasmic protein that blocks cell cycle progression from the G0/G1 to S phase.

Matsumine A, Senda T, Baeg GH, Roy BC, Nakamura Y, Noda M, Toyoshima K, Akiyama T.

J Biol Chem. 1996 Apr 26;271(17):10341-6.

46.

The tumour suppressor gene product APC blocks cell cycle progression from G0/G1 to S phase.

Baeg GH, Matsumine A, Kuroda T, Bhattacharjee RN, Miyashiro I, Toyoshima K, Akiyama T.

EMBO J. 1995 Nov 15;14(22):5618-25.

47.

Subcellular localization of the APC protein: immunoelectron microscopic study of the association of the APC protein with catenin.

Miyashiro I, Senda T, Matsumine A, Baeg GH, Kuroda T, Shimano T, Miura S, Noda T, Kobayashi S, Monden M, et al.

Oncogene. 1995 Jul 6;11(1):89-96.

PMID:
7624136

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