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Items: 19

1.

Continuous directed evolution of proteins with improved soluble expression.

Wang T, Badran AH, Huang TP, Liu DR.

Nat Chem Biol. 2018 Oct;14(10):972-980. doi: 10.1038/s41589-018-0121-5. Epub 2018 Aug 20.

2.

Publisher Correction: Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.

Gaudelli NM, Komor AC, Rees HA, Packer MS, Badran AH, Bryson DI, Liu DR.

Nature. 2018 Jul;559(7714):E8. doi: 10.1038/s41586-018-0070-x.

PMID:
29720650
3.

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.

Gaudelli NM, Komor AC, Rees HA, Packer MS, Badran AH, Bryson DI, Liu DR.

Nature. 2017 Nov 23;551(7681):464-471. doi: 10.1038/nature24644. Epub 2017 Oct 25. Erratum in: Nature. 2018 May 2;:.

4.

Modern methods for laboratory diversification of biomolecules.

Bratulic S, Badran AH.

Curr Opin Chem Biol. 2017 Dec;41:50-60. doi: 10.1016/j.cbpa.2017.10.010. Epub 2017 Nov 2. Review.

5.

Editing the Genome Without Double-Stranded DNA Breaks.

Komor AC, Badran AH, Liu DR.

ACS Chem Biol. 2018 Feb 16;13(2):383-388. doi: 10.1021/acschembio.7b00710. Epub 2017 Oct 9. Review.

6.

Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity.

Komor AC, Zhao KT, Packer MS, Gaudelli NM, Waterbury AL, Koblan LW, Kim YB, Badran AH, Liu DR.

Sci Adv. 2017 Aug 30;3(8):eaao4774. doi: 10.1126/sciadv.aao4774. eCollection 2017 Aug.

7.

CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes.

Komor AC, Badran AH, Liu DR.

Cell. 2017 Apr 20;169(3):559. doi: 10.1016/j.cell.2017.04.005. No abstract available.

8.

CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes.

Komor AC, Badran AH, Liu DR.

Cell. 2017 Jan 12;168(1-2):20-36. doi: 10.1016/j.cell.2016.10.044. Epub 2016 Nov 17. Review. Erratum in: Cell. 2017 Apr 20;169(3):559.

9.

Continuous evolution of Bacillus thuringiensis toxins overcomes insect resistance.

Badran AH, Guzov VM, Huai Q, Kemp MM, Vishwanath P, Kain W, Nance AM, Evdokimov A, Moshiri F, Turner KH, Wang P, Malvar T, Liu DR.

Nature. 2016 May 5;533(7601):58-63. doi: 10.1038/nature17938. Epub 2016 Apr 27.

10.

Development of potent in vivo mutagenesis plasmids with broad mutational spectra.

Badran AH, Liu DR.

Nat Commun. 2015 Oct 7;6:8425. doi: 10.1038/ncomms9425.

11.

Continuous directed evolution of DNA-binding proteins to improve TALEN specificity.

Hubbard BP, Badran AH, Zuris JA, Guilinger JP, Davis KM, Chen L, Tsai SQ, Sander JD, Joung JK, Liu DR.

Nat Methods. 2015 Oct;12(10):939-42. doi: 10.1038/nmeth.3515. Epub 2015 Aug 10.

12.

In vivo continuous directed evolution.

Badran AH, Liu DR.

Curr Opin Chem Biol. 2015 Feb;24:1-10. doi: 10.1016/j.cbpa.2014.09.040. Epub 2014 Nov 7. Review.

13.

A system for the continuous directed evolution of proteases rapidly reveals drug-resistance mutations.

Dickinson BC, Packer MS, Badran AH, Liu DR.

Nat Commun. 2014 Oct 30;5:5352. doi: 10.1038/ncomms6352.

14.

Negative selection and stringency modulation in phage-assisted continuous evolution.

Carlson JC, Badran AH, Guggiana-Nilo DA, Liu DR.

Nat Chem Biol. 2014 Mar;10(3):216-22. doi: 10.1038/nchembio.1453. Epub 2014 Feb 2.

15.

Evaluating the global CpG methylation status of native DNA utilizing a bipartite split-luciferase sensor.

Badran AH, Furman JL, Ma AS, Comi TJ, Porter JR, Ghosh I.

Anal Chem. 2011 Sep 15;83(18):7151-7. doi: 10.1021/ac2015239. Epub 2011 Aug 23.

16.

Turn-on DNA damage sensors for the direct detection of 8-oxoguanine and photoproducts in native DNA.

Furman JL, Mok PW, Badran AH, Ghosh I.

J Am Chem Soc. 2011 Aug 17;133(32):12518-27. doi: 10.1021/ja1116606. Epub 2011 May 17.

17.

Toward a general approach for RNA-templated hierarchical assembly of split-proteins.

Furman JL, Badran AH, Ajulo O, Porter JR, Stains CI, Segal DJ, Ghosh I.

J Am Chem Soc. 2010 Aug 25;132(33):11692-701. doi: 10.1021/ja104395b.

18.

Direct DNA methylation profiling using methyl binding domain proteins.

Yu Y, Blair S, Gillespie D, Jensen R, Myszka D, Badran AH, Ghosh I, Chagovetz A.

Anal Chem. 2010 Jun 15;82(12):5012-9. doi: 10.1021/ac1010316.

19.

Systematic evaluation of split-fluorescent proteins for the direct detection of native and methylated DNA.

Furman JL, Badran AH, Shen S, Stains CI, Hannallah J, Segal DJ, Ghosh I.

Bioorg Med Chem Lett. 2009 Jul 15;19(14):3748-51. doi: 10.1016/j.bmcl.2009.04.141. Epub 2009 May 5.

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