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Items: 46


Similarities and Differences Between Staphylococcal and Streptococcal Toxic Shock Syndromes in Children: Results From a 30-Case Cohort.

Javouhey E, Bolze PA, Jamen C, Lina G, Badiou C, Poyart C, Portefaix A, Tristan A, Laurent F, Bes M, Vandenesch F, Gilletand Y, Dauwalder O.

Front Pediatr. 2018 Nov 28;6:360. doi: 10.3389/fped.2018.00360. eCollection 2018.


Clindamycin suppresses virulence expression in inducible clindamycin-resistant Staphylococcus aureus strains.

Hodille E, Badiou C, Bouveyron C, Bes M, Tristan A, Vandenesch F, Lina G, Dumitrescu O.

Ann Clin Microbiol Antimicrob. 2018 Oct 20;17(1):38. doi: 10.1186/s12941-018-0291-8.


Understanding the Virulence of Staphylococcus pseudintermedius: A Major Role of Pore-Forming Toxins.

Maali Y, Badiou C, Martins-Simões P, Hodille E, Bes M, Vandenesch F, Lina G, Diot A, Laurent F, Trouillet-Assant S.

Front Cell Infect Microbiol. 2018 Jun 28;8:221. doi: 10.3389/fcimb.2018.00221. eCollection 2018.


Synergistic Effects of Influenza and Staphylococcus aureus Toxins on Inflammation Activation and Cytotoxicity in Human Monocytic Cell Lines.

Jeannoel M, Casalegno JS, Ottmann M, Badiou C, Dumitrescu O, Lina B, Lina G.

Toxins (Basel). 2018 Jul 11;10(7). pii: E286. doi: 10.3390/toxins10070286.


Impact of Currently Marketed Tampons and Menstrual Cups on Staphylococcus aureus Growth and Toxic Shock Syndrome Toxin 1 Production In Vitro.

Nonfoux L, Chiaruzzi M, Badiou C, Baude J, Tristan A, Thioulouse J, Muller D, Prigent-Combaret C, Lina G.

Appl Environ Microbiol. 2018 May 31;84(12). pii: e00351-18. doi: 10.1128/AEM.00351-18. Print 2018 Jun 15.


Effects of Tedizolid Phosphate on Survival Outcomes and Suppression of Production of Staphylococcal Toxins in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia.

Le VT, Le HN, Pinheiro MG, Hahn KJ, Dinh ML, Larson KB, Flanagan SD, Badiou C, Lina G, Tkaczyk C, Sellman BR, Diep BA.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02734-16. doi: 10.1128/AAC.02734-16. Print 2017 Apr.


Delta Hemolysin and Phenol-Soluble Modulins, but Not Alpha Hemolysin or Panton-Valentine Leukocidin, Induce Mast Cell Activation.

Hodille E, Cuerq C, Badiou C, Bienvenu F, Steghens JP, Cartier R, Bes M, Tristan A, Plesa A, Le VT, Diep BA, Lina G, Dumitrescu O.

Front Cell Infect Microbiol. 2016 Dec 12;6:180. doi: 10.3389/fcimb.2016.00180. eCollection 2016.


IVIG-mediated protection against necrotizing pneumonia caused by MRSA.

Diep BA, Le VT, Badiou C, Le HN, Pinheiro MG, Duong AH, Wang X, Dip EC, Aguiar-Alves F, Basuino L, Marbach H, Mai TT, Sarda MN, Kajikawa O, Matute-Bello G, Tkaczyk C, Rasigade JP, Sellman BR, Chambers HF, Lina G.

Sci Transl Med. 2016 Sep 21;8(357):357ra124. doi: 10.1126/scitranslmed.aag1153.


Staphylococcal Enterotoxin O Exhibits Cell Cycle Modulating Activity.

Hodille E, Alekseeva L, Berkova N, Serrier A, Badiou C, Gilquin B, Brun V, Vandenesch F, Terman DS, Lina G.

Front Microbiol. 2016 Apr 15;7:441. doi: 10.3389/fmicb.2016.00441. eCollection 2016.


Human Monocyte-Derived Osteoclasts Are Targeted by Staphylococcal Pore-Forming Toxins and Superantigens.

Flammier S, Rasigade JP, Badiou C, Henry T, Vandenesch F, Laurent F, Trouillet-Assant S.

PLoS One. 2016 Mar 2;11(3):e0150693. doi: 10.1371/journal.pone.0150693. eCollection 2016.


Correction: Effects of the Staphylococcus aureus and Staphylococcus epidermidis Secretomes Isolated from the Skin Microbiota of Atopic Children on CD4+ T Cell Activation.

Laborel-Préneron E, Bianchi P, Boralevi F, Lehours P, Fraysse F, Morice-Picard F, Sugai M, Sato'o Y, Badiou C, Lina G, Schmitt AM, Redoulès D, Casas C, Davrinche C.

PLoS One. 2015 Nov 30;10(11):e0144323. doi: 10.1371/journal.pone.0144323. eCollection 2015. No abstract available.


Effects of the Staphylococcus aureus and Staphylococcus epidermidis Secretomes Isolated from the Skin Microbiota of Atopic Children on CD4+ T Cell Activation.

Laborel-Préneron E, Bianchi P, Boralevi F, Lehours P, Fraysse F, Morice-Picard F, Sugai M, Sato'o Y, Badiou C, Lina G, Schmitt AM, Redoulès D, Casas C, Davrinche C.

PLoS One. 2015 Oct 28;10(10):e0141067. doi: 10.1371/journal.pone.0141067. eCollection 2015. Erratum in: PLoS One. 2015;10(11):e0144323.


Staphylococcus aureus Targets the Duffy Antigen Receptor for Chemokines (DARC) to Lyse Erythrocytes.

Spaan AN, Reyes-Robles T, Badiou C, Cochet S, Boguslawski KM, Yoong P, Day CJ, de Haas CJ, van Kessel KP, Vandenesch F, Jennings MP, Le Van Kim C, Colin Y, van Strijp JA, Henry T, Torres VJ.

Cell Host Microbe. 2015 Sep 9;18(3):363-70. doi: 10.1016/j.chom.2015.08.001. Epub 2015 Aug 27.


Differential Interaction of the Staphylococcal Toxins Panton-Valentine Leukocidin and γ-Hemolysin CB with Human C5a Receptors.

Spaan AN, Schiepers A, de Haas CJ, van Hooijdonk DD, Badiou C, Contamin H, Vandenesch F, Lina G, Gerard NP, Gerard C, van Kessel KP, Henry T, van Strijp JA.

J Immunol. 2015 Aug 1;195(3):1034-43. doi: 10.4049/jimmunol.1500604. Epub 2015 Jun 19.


α-Defensins partially protect human neutrophils against Panton-Valentine leukocidin produced by Staphylococcus aureus.

Cardot-Martin E, Casalegno JS, Badiou C, Dauwalder O, Keller D, Prévost G, Rieg S, Kern WV, Cuerq C, Etienne J, Vandenesch F, Lina G, Dumitrescu O.

Lett Appl Microbiol. 2015 Aug;61(2):158-64. doi: 10.1111/lam.12438. Epub 2015 Jun 1.


Impacts of enterotoxin gene cluster-encoded superantigens on local and systemic experimental Staphylococcus aureus infections.

Nowrouzian FL, Ali A, Badiou C, Dauwalder O, Lina G, Josefsson E.

Eur J Clin Microbiol Infect Dis. 2015 Jul;34(7):1443-9. doi: 10.1007/s10096-015-2371-4. Epub 2015 Apr 12.


The levels of antibodies to Panton-Valentine leukocidin (PVL) vary with PVL prevalence along a north-to-south gradient.

Rasigade JP, Trouillet-Assant S, Breurec S, Antri K, Lina G, Bes M, Tristan A, Badiou C, Bernelin M, Fall C, Ramdani-Bouguessa N, Etienne J, Vandenesch F, Laurent F.

Eur J Clin Microbiol Infect Dis. 2015 May;34(5):927-33. doi: 10.1007/s10096-014-2307-4. Epub 2015 Jan 10.


Community-acquired meticillin-resistant Staphylococcus aureus strain USA300 resists staphylococcal protein A modulation by antibiotics and antimicrobial peptides.

Cardot Martin E, Michel A, Raynal B, Badiou C, Laurent F, Vandenesch F, Etienne J, Lina G, Dumitrescu O.

Int J Antimicrob Agents. 2015 Jan;45(1):19-24. doi: 10.1016/j.ijantimicag.2014.08.009. Epub 2014 Oct 2.


The staphylococcal toxins γ-haemolysin AB and CB differentially target phagocytes by employing specific chemokine receptors.

Spaan AN, Vrieling M, Wallet P, Badiou C, Reyes-Robles T, Ohneck EA, Benito Y, de Haas CJ, Day CJ, Jennings MP, Lina G, Vandenesch F, van Kessel KP, Torres VJ, van Strijp JA, Henry T.

Nat Commun. 2014 Nov 11;5:5438. doi: 10.1038/ncomms6438.


Kineret®/IL-1ra blocks the IL-1/IL-8 inflammatory cascade during recombinant Panton Valentine Leukocidin-triggered pneumonia but not during S. aureus infection.

Labrousse D, Perret M, Hayez D, Da Silva S, Badiou C, Couzon F, Bes M, Chavanet P, Lina G, Vandenesch F, Croisier-Bertin D, Henry T.

PLoS One. 2014 Jun 6;9(6):e97546. doi: 10.1371/journal.pone.0097546. eCollection 2014.


In vivo efficacy of ceftaroline fosamil in a methicillin-resistant panton-valentine leukocidin-producing Staphylococcus aureus rabbit pneumonia model.

Croisier-Bertin D, Hayez D, Da Silva S, Labrousse D, Biek D, Badiou C, Dumitrescu O, Guerard P, Charles PE, Piroth L, Lina G, Vandenesch F, Chavanet P.

Antimicrob Agents Chemother. 2014;58(4):1855-61. doi: 10.1128/AAC.01707-13. Epub 2014 Jan 6.


Staphylococcal entertotoxins of the enterotoxin gene cluster (egcSEs) induce nitrous oxide- and cytokine dependent tumor cell apoptosis in a broad panel of human tumor cells.

Terman DS, Serier A, Dauwalder O, Badiou C, Dutour A, Thomas D, Brun V, Bienvenu J, Etienne J, Vandenesch F, Lina G.

Front Cell Infect Microbiol. 2013 Aug 13;3:38. doi: 10.3389/fcimb.2013.00038. eCollection 2013.


PSMs of hypervirulent Staphylococcus aureus act as intracellular toxins that kill infected osteoblasts.

Rasigade JP, Trouillet-Assant S, Ferry T, Diep BA, Sapin A, Lhoste Y, Ranfaing J, Badiou C, Benito Y, Bes M, Couzon F, Tigaud S, Lina G, Etienne J, Vandenesch F, Laurent F.

PLoS One. 2013 May 14;8(5):e63176. doi: 10.1371/journal.pone.0063176. Print 2013.


The staphylococcal toxin Panton-Valentine Leukocidin targets human C5a receptors.

Spaan AN, Henry T, van Rooijen WJM, Perret M, Badiou C, Aerts PC, Kemmink J, de Haas CJC, van Kessel KPM, Vandenesch F, Lina G, van Strijp JAG.

Cell Host Microbe. 2013 May 15;13(5):584-594. doi: 10.1016/j.chom.2013.04.006.


Effects of linezolid on suppressing in vivo production of staphylococcal toxins and improving survival outcomes in a rabbit model of methicillin-resistant Staphylococcus aureus necrotizing pneumonia.

Diep BA, Afasizheva A, Le HN, Kajikawa O, Matute-Bello G, Tkaczyk C, Sellman B, Badiou C, Lina G, Chambers HF.

J Infect Dis. 2013 Jul;208(1):75-82. doi: 10.1093/infdis/jit129. Epub 2013 Mar 26.


Effects of subinhibitory concentrations of antibiotics on virulence factor expression by community-acquired methicillin-resistant Staphylococcus aureus.

Otto MP, Martin E, Badiou C, Lebrun S, Bes M, Vandenesch F, Etienne J, Lina G, Dumitrescu O.

J Antimicrob Chemother. 2013 Jul;68(7):1524-32. doi: 10.1093/jac/dkt073. Epub 2013 Mar 18.


Assessment of cellular immune parameters in paediatric toxic shock syndrome: a report of five cases.

Dauwalder O, Venet F, Javouhey E, Badiou C, Gillet Y, Guignant C, Plainvert C, Etienne J, Poyart C, Vandenesch F, Lina G, Monneret G.

FEMS Immunol Med Microbiol. 2012 Oct;66(1):116-9. doi: 10.1111/j.1574-695X.2012.00990.x. Epub 2012 Jun 18.


Cross-talk between Staphylococcus aureus leukocidins-intoxicated macrophages and lung epithelial cells triggers chemokine secretion in an inflammasome-dependent manner.

Perret M, Badiou C, Lina G, Burbaud S, Benito Y, Bes M, Cottin V, Couzon F, Juruj C, Dauwalder O, Goutagny N, Diep BA, Vandenesch F, Henry T.

Cell Microbiol. 2012 Jul;14(7):1019-36. doi: 10.1111/j.1462-5822.2012.01772.x. Epub 2012 Mar 5.


Do differences in Panton-Valentine leukocidin production among international methicillin-resistant Staphylococcus aureus clones affect disease presentation and severity?

Boakes E, Kearns AM, Badiou C, Lina G, Hill RL, Ellington MJ.

J Clin Microbiol. 2012 May;50(5):1773-6. doi: 10.1128/JCM.06421-11. Epub 2012 Jan 11.


Simulated antibiotic exposures in an in vitro hollow-fiber infection model influence toxin gene expression and production in community-associated methicillin-resistant Staphylococcus aureus strain MW2.

Pichereau S, Pantrangi M, Couet W, Badiou C, Lina G, Shukla SK, Rose WE.

Antimicrob Agents Chemother. 2012 Jan;56(1):140-7. doi: 10.1128/AAC.05113-11. Epub 2011 Nov 7.


Panton-Valentine leukocidin does play a role in the early stage of Staphylococcus aureus skin infections: a rabbit model.

Lipinska U, Hermans K, Meulemans L, Dumitrescu O, Badiou C, Duchateau L, Haesebrouck F, Etienne J, Lina G.

PLoS One. 2011;6(8):e22864. doi: 10.1371/journal.pone.0022864. Epub 2011 Aug 5.


Beta-lactams interfering with PBP1 induce Panton-Valentine leukocidin expression by triggering sarA and rot global regulators of Staphylococcus aureus.

Dumitrescu O, Choudhury P, Boisset S, Badiou C, Bes M, Benito Y, Wolz C, Vandenesch F, Etienne J, Cheung AL, Bowden MG, Lina G.

Antimicrob Agents Chemother. 2011 Jul;55(7):3261-71. doi: 10.1128/AAC.01401-10. Epub 2011 Apr 18.


Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury.

Diep BA, Chan L, Tattevin P, Kajikawa O, Martin TR, Basuino L, Mai TT, Marbach H, Braughton KR, Whitney AR, Gardner DJ, Fan X, Tseng CW, Liu GY, Badiou C, Etienne J, Lina G, Matthay MA, DeLeo FR, Chambers HF.

Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5587-92. doi: 10.1073/pnas.0912403107. Epub 2010 Mar 15.


Rapid detection of Staphylococcus aureus Panton-Valentine leukocidin in clinical specimens by enzyme-linked immunosorbent assay and immunochromatographic tests.

Badiou C, Dumitrescu O, George N, Forbes AR, Drougka E, Chan KS, Ramdani-Bouguessa N, Meugnier H, Bes M, Vandenesch F, Etienne J, Hsu LY, Tazir M, Spiliopoulou I, Nimmo GR, Hulten KG, Lina G.

J Clin Microbiol. 2010 Apr;48(4):1384-90. doi: 10.1128/JCM.02274-09. Epub 2010 Feb 3.


Immunogenicity of toxins during Staphylococcus aureus infection.

Verkaik NJ, Dauwalder O, Antri K, Boubekri I, de Vogel CP, Badiou C, Bes M, Vandenesch F, Tazir M, Hooijkaas H, Verbrugh HA, van Belkum A, Etienne J, Lina G, Ramdani-Bouguessa N, van Wamel WJ.

Clin Infect Dis. 2010 Jan 1;50(1):61-8. doi: 10.1086/648673.


Indirubin derivatives inhibit malignant lymphoid cell proliferation.

Chebel A, Kagialis-Girard S, Catallo R, Chien WW, Mialou V, Domenech C, Badiou C, Tigaud I, Ffrench M.

Leuk Lymphoma. 2009 Dec;50(12):2049-60. doi: 10.3109/10428190903288449.


A histidine-to-arginine substitution in Panton-Valentine leukocidin from USA300 community-acquired methicillin-resistant Staphylococcus aureus does not impair its leukotoxicity.

Besseyre des Horts T, Dumitrescu O, Badiou C, Thomas D, Benito Y, Etienne J, Vandenesch F, Lina G.

Infect Immun. 2010 Jan;78(1):260-4. doi: 10.1128/IAI.00843-09. Epub 2009 Oct 12.


Early kinetics of the transcriptional response of human leukocytes to staphylococcal superantigenic enterotoxins A and G.

Dauwalder O, Pachot A, Cazalis MA, Paye M, Faudot C, Badiou C, Mougin B, Vandenesch F, Etienne J, Lina G, Monneret G.

Microb Pathog. 2009 Sep;47(3):171-6. doi: 10.1016/j.micpath.2009.07.001. Epub 2009 Jul 8.


Staphylococcus aureus superantigens elicit redundant and extensive human Vbeta patterns.

Thomas D, Dauwalder O, Brun V, Badiou C, Ferry T, Etienne J, Vandenesch F, Lina G.

Infect Immun. 2009 May;77(5):2043-50. doi: 10.1128/IAI.01388-08. Epub 2009 Mar 2.


Serum antibodies against Panton-Valentine leukocidin in a normal population and during Staphylococcus aureus infection.

Croze M, Dauwalder O, Dumitrescu O, Badiou C, Gillet Y, Genestier AL, Vandenesch F, Etienne J, Lina G.

Clin Microbiol Infect. 2009 Feb;15(2):144-8. doi: 10.1111/j.1469-0691.2008.02650.x. Epub 2009 Jan 10.


The Panton-Valentine leukocidin vaccine protects mice against lung and skin infections caused by Staphylococcus aureus USA300.

Brown EL, Dumitrescu O, Thomas D, Badiou C, Koers EM, Choudhury P, Vazquez V, Etienne J, Lina G, Vandenesch F, Bowden MG.

Clin Microbiol Infect. 2009 Feb;15(2):156-64. doi: 10.1111/j.1469-0691.2008.02648.x. Epub 2008 Dec 22.


Panton-Valentine leukocidin is expressed at toxic levels in human skin abscesses.

Badiou C, Dumitrescu O, Croze M, Gillet Y, Dohin B, Slayman DH, Allaouchiche B, Etienne J, Vandenesch F, Lina G.

Clin Microbiol Infect. 2008 Dec;14(12):1180-3. doi: 10.1111/j.1469-0691.2008.02105.x. Epub 2008 Nov 21.


Effect of antibiotics, alone and in combination, on Panton-Valentine leukocidin production by a Staphylococcus aureus reference strain.

Dumitrescu O, Badiou C, Bes M, Reverdy ME, Vandenesch F, Etienne J, Lina G.

Clin Microbiol Infect. 2008 Apr;14(4):384-8. doi: 10.1111/j.1469-0691.2007.01947.x. Epub 2008 Feb 2.


Inhibition of normal lymphocyte proliferation by Indirubin-3'-monoxime: a multifactorial process.

Kagialis-Girard S, Mialou V, Chebel A, Chien WW, Tigaud I, Mokdad F, Badiou C, Ffrench M.

Leuk Lymphoma. 2007 Mar;48(3):605-15.


Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin.

Dumitrescu O, Boisset S, Badiou C, Bes M, Benito Y, Reverdy ME, Vandenesch F, Etienne J, Lina G.

Antimicrob Agents Chemother. 2007 Apr;51(4):1515-9. Epub 2007 Jan 22.


Comparative inflammatory properties of staphylococcal superantigenic enterotoxins SEA and SEG: implications for septic shock.

Dauwalder O, Thomas D, Ferry T, Debard AL, Badiou C, Vandenesch F, Etienne J, Lina G, Monneret G.

J Leukoc Biol. 2006 Oct;80(4):753-8. Epub 2006 Aug 2.


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