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Items: 46

1.

Three-Dimensional and Chemical Mapping of Intracellular Signaling Nanodomains in Health and Disease with Enhanced Expansion Microscopy.

Sheard TMD, Hurley ME, Colyer J, White E, Norman R, Pervolaraki E, Narayanasamy KK, Hou Y, Kirton HM, Yang Z, Hunter L, Shim JU, Clowsley AH, Smith AJ, Baddeley D, Soeller C, Colman MA, Jayasinghe I.

ACS Nano. 2019 Feb 26;13(2):2143-2157. doi: 10.1021/acsnano.8b08742. Epub 2019 Feb 8.

2.

S-Palmitoylation Sorts Membrane Cargo for Anterograde Transport in the Golgi.

Ernst AM, Syed SA, Zaki O, Bottanelli F, Zheng H, Hacke M, Xi Z, Rivera-Molina F, Graham M, Rebane AA, Björkholm P, Baddeley D, Toomre D, Pincet F, Rothman JE.

Dev Cell. 2018 Nov 19;47(4):479-493.e7. doi: 10.1016/j.devcel.2018.10.024.

PMID:
30458139
3.

Dynamic nanoscale morphology of the ER surveyed by STED microscopy.

Schroeder LK, Barentine AES, Merta H, Schweighofer S, Zhang Y, Baddeley D, Bewersdorf J, Bahmanyar S.

J Cell Biol. 2019 Jan 7;218(1):83-96. doi: 10.1083/jcb.201809107. Epub 2018 Nov 15.

4.

Simultaneously Measuring Image Features and Resolution in Live-Cell STED Images.

Barentine AES, Schroeder LK, Graff M, Baddeley D, Bewersdorf J.

Biophys J. 2018 Sep 18;115(6):951-956. doi: 10.1016/j.bpj.2018.07.028. Epub 2018 Aug 4.

5.

A Programmable DNA Origami Platform for Organizing Intrinsically Disordered Nucleoporins within Nanopore Confinement.

Fisher PDE, Shen Q, Akpinar B, Davis LK, Chung KKH, Baddeley D, Šarić A, Melia TJ, Hoogenboom BW, Lin C, Lusk CP.

ACS Nano. 2018 Feb 27;12(2):1508-1518. doi: 10.1021/acsnano.7b08044. Epub 2018 Jan 25.

6.

True Molecular Scale Visualization of Variable Clustering Properties of Ryanodine Receptors.

Jayasinghe I, Clowsley AH, Lin R, Lutz T, Harrison C, Green E, Baddeley D, Di Michele L, Soeller C.

Cell Rep. 2018 Jan 9;22(2):557-567. doi: 10.1016/j.celrep.2017.12.045.

7.

Biological Insight from Super-Resolution Microscopy: What We Can Learn from Localization-Based Images.

Baddeley D, Bewersdorf J.

Annu Rev Biochem. 2018 Jun 20;87:965-989. doi: 10.1146/annurev-biochem-060815-014801. Epub 2017 Dec 22.

PMID:
29272143
8.

Correlative Single-Molecule Localization Microscopy and Confocal Microscopy.

Soeller C, Hou Y, Jayasinghe ID, Baddeley D, Crossman D.

Methods Mol Biol. 2017;1663:205-217. doi: 10.1007/978-1-4939-7265-4_17.

PMID:
28924670
9.

Algorithmic corrections for localization microscopy with sCMOS cameras - characterisation of a computationally efficient localization approach.

Lin R, Clowsley AH, Jayasinghe ID, Baddeley D, Soeller C.

Opt Express. 2017 May 15;25(10):11701-11716. doi: 10.1364/OE.25.011701.

10.

Single-molecule imaging of the BAR-domain protein Pil1p reveals filament-end dynamics.

Lacy MM, Baddeley D, Berro J.

Mol Biol Cell. 2017 Aug 15;28(17):2251-2259. doi: 10.1091/mbc.E17-04-0238. Epub 2017 Jun 28.

11.

Increased collagen within the transverse tubules in human heart failure.

Crossman DJ, Shen X, Jüllig M, Munro M, Hou Y, Middleditch M, Shrestha D, Li A, Lal S, Dos Remedios CG, Baddeley D, Ruygrok PN, Soeller C.

Cardiovasc Res. 2017 Jul 1;113(8):879-891. doi: 10.1093/cvr/cvx055.

PMID:
28444133
12.

A novel physiological role for ARF1 in the formation of bidirectional tubules from the Golgi.

Bottanelli F, Kilian N, Ernst AM, Rivera-Molina F, Schroeder LK, Kromann EB, Lessard MD, Erdmann RS, Schepartz A, Baddeley D, Bewersdorf J, Toomre D, Rothman JE.

Mol Biol Cell. 2017 Jun 15;28(12):1676-1687. doi: 10.1091/mbc.E16-12-0863. Epub 2017 Apr 20.

13.

N-terminal SAP97 isoforms differentially regulate synaptic structure and postsynaptic surface pools of AMPA receptors.

Goodman L, Baddeley D, Ambroziak W, Waites CL, Garner CC, Soeller C, Montgomery JM.

Hippocampus. 2017 Jun;27(6):668-682. doi: 10.1002/hipo.22723. Epub 2017 Mar 20.

PMID:
28244171
14.

Junctophilin-2 in the nanoscale organisation and functional signalling of ryanodine receptor clusters in cardiomyocytes.

Munro ML, Jayasinghe ID, Wang Q, Quick A, Wang W, Baddeley D, Wehrens XH, Soeller C.

J Cell Sci. 2016 Dec 1;129(23):4388-4398. Epub 2016 Oct 21.

15.

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.

Yuan P, Condello C, Keene CD, Wang Y, Bird TD, Paul SM, Luo W, Colonna M, Baddeley D, Grutzendler J.

Neuron. 2016 Oct 5;92(1):252-264. doi: 10.1016/j.neuron.2016.09.016. No abstract available.

16.

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.

Yuan P, Condello C, Keene CD, Wang Y, Bird TD, Paul SM, Luo W, Colonna M, Baddeley D, Grutzendler J.

Neuron. 2016 May 18;90(4):724-39. doi: 10.1016/j.neuron.2016.05.003.

17.

Cholesterol Increases the Openness of SNARE-Mediated Flickering Fusion Pores.

Stratton BS, Warner JM, Wu Z, Nikolaus J, Wei G, Wagnon E, Baddeley D, Karatekin E, O'Shaughnessy B.

Biophys J. 2016 Apr 12;110(7):1538-1550. doi: 10.1016/j.bpj.2016.02.019.

18.

Two-colour live-cell nanoscale imaging of intracellular targets.

Bottanelli F, Kromann EB, Allgeyer ES, Erdmann RS, Wood Baguley S, Sirinakis G, Schepartz A, Baddeley D, Toomre DK, Rothman JE, Bewersdorf J.

Nat Commun. 2016 Mar 4;7:10778. doi: 10.1038/ncomms10778.

19.

Detecting nano-scale protein clustering.

Baddeley D.

Nat Methods. 2015 Nov;12(11):1019-20. doi: 10.1038/nmeth.3641. No abstract available.

PMID:
26513552
20.

Combining confocal and single molecule localisation microscopy: A correlative approach to multi-scale tissue imaging.

Crossman DJ, Hou Y, Jayasinghe I, Baddeley D, Soeller C.

Methods. 2015 Oct 15;88:98-108. doi: 10.1016/j.ymeth.2015.03.011. Epub 2015 Mar 24.

PMID:
25814438
21.

Nanoscale analysis of ryanodine receptor clusters in dyadic couplings of rat cardiac myocytes.

Hou Y, Jayasinghe I, Crossman DJ, Baddeley D, Soeller C.

J Mol Cell Cardiol. 2015 Mar;80:45-55. doi: 10.1016/j.yjmcc.2014.12.013. Epub 2014 Dec 20.

PMID:
25536181
22.

Observation of the molecular organization of calcium release sites in fast- and slow-twitch skeletal muscle with nanoscale imaging.

Jayasinghe ID, Munro M, Baddeley D, Launikonis BS, Soeller C.

J R Soc Interface. 2014 Oct 6;11(99). pii: 20140570. doi: 10.1098/rsif.2014.0570.

23.

Super-resolution fluorescence imaging to study cardiac biophysics: α-actinin distribution and Z-disk topologies in optically thick cardiac tissue slices.

Hou Y, Crossman DJ, Rajagopal V, Baddeley D, Jayasinghe I, Soeller C.

Prog Biophys Mol Biol. 2014 Aug;115(2-3):328-39. doi: 10.1016/j.pbiomolbio.2014.07.003. Epub 2014 Jul 18.

PMID:
25042577
24.

Nanoscale distribution of ryanodine receptors and caveolin-3 in mouse ventricular myocytes: dilation of t-tubules near junctions.

Wong J, Baddeley D, Bushong EA, Yu Z, Ellisman MH, Hoshijima M, Soeller C.

Biophys J. 2013 Jun 4;104(11):L22-4. doi: 10.1016/j.bpj.2013.02.059.

25.

Examination of the subsarcolemmal tubular system of mammalian skeletal muscle fibers.

Jayasinghe ID, Lo HP, Morgan GP, Baddeley D, Parton RG, Soeller C, Launikonis BS.

Biophys J. 2013 Jun 4;104(11):L19-21. doi: 10.1016/j.bpj.2013.04.029.

26.

Super-resolution imaging of EC coupling protein distribution in the heart.

Soeller C, Baddeley D.

J Mol Cell Cardiol. 2013 May;58:32-40. doi: 10.1016/j.yjmcc.2012.11.004. Epub 2012 Nov 13. Review.

PMID:
23159441
27.

Nanoscale organization of junctophilin-2 and ryanodine receptors within peripheral couplings of rat ventricular cardiomyocytes.

Jayasinghe ID, Baddeley D, Kong CH, Wehrens XH, Cannell MB, Soeller C.

Biophys J. 2012 Mar 7;102(5):L19-21. doi: 10.1016/j.bpj.2012.01.034. Epub 2012 Mar 6.

28.

4D super-resolution microscopy with conventional fluorophores and single wavelength excitation in optically thick cells and tissues.

Baddeley D, Crossman D, Rossberger S, Cheyne JE, Montgomery JM, Jayasinghe ID, Cremer C, Cannell MB, Soeller C.

PLoS One. 2011;6(5):e20645. doi: 10.1371/journal.pone.0020645. Epub 2011 May 31.

29.

Epigenetic regulation of promiscuous gene expression in thymic medullary epithelial cells.

Tykocinski LO, Sinemus A, Rezavandy E, Weiland Y, Baddeley D, Cremer C, Sonntag S, Willecke K, Derbinski J, Kyewski B.

Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19426-31. doi: 10.1073/pnas.1009265107. Epub 2010 Oct 21.

30.

Structured illumination microscopy of autofluorescent aggregations in human tissue.

Best G, Amberger R, Baddeley D, Ach T, Dithmar S, Heintzmann R, Cremer C.

Micron. 2011 Jun;42(4):330-5. doi: 10.1016/j.micron.2010.06.016. Epub 2010 Sep 15.

PMID:
20926302
31.

Visualization of localization microscopy data.

Baddeley D, Cannell MB, Soeller C.

Microsc Microanal. 2010 Feb;16(1):64-72. doi: 10.1017/S143192760999122X.

PMID:
20082730
32.

Model based precision structural measurements on barely resolved objects.

Baddeley D, Weiland Y, Batram C, Birk U, Cremer C.

J Microsc. 2010 Jan;237(1):70-8. doi: 10.1111/j.1365-2818.2009.03304.x.

33.

Optical single-channel resolution imaging of the ryanodine receptor distribution in rat cardiac myocytes.

Baddeley D, Jayasinghe ID, Lam L, Rossberger S, Cannell MB, Soeller C.

Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22275-80. doi: 10.1073/pnas.0908971106. Epub 2009 Dec 15.

34.

Measurement of replication structures at the nanometer scale using super-resolution light microscopy.

Baddeley D, Chagin VO, Schermelleh L, Martin S, Pombo A, Carlton PM, Gahl A, Domaing P, Birk U, Leonhardt H, Cremer C, Cardoso MC.

Nucleic Acids Res. 2010 Jan;38(2):e8. doi: 10.1093/nar/gkp901. Epub 2009 Oct 28.

35.

Using conventional fluorescent markers for far-field fluorescence localization nanoscopy allows resolution in the 10-nm range.

Lemmer P, Gunkel M, Weiland Y, Müller P, Baddeley D, Kaufmann R, Urich A, Eipel H, Amberger R, Hausmann M, Cremer C.

J Microsc. 2009 Aug;235(2):163-71. doi: 10.1111/j.1365-2818.2009.03196.x.

36.

Light-induced dark states of organic fluochromes enable 30 nm resolution imaging in standard media.

Baddeley D, Jayasinghe ID, Cremer C, Cannell MB, Soeller C.

Biophys J. 2009 Jan;96(2):L22-4. doi: 10.1016/j.bpj.2008.11.002.

37.

Nanosizing by spatially modulated illumination (SMI) microscopy and applications to the nucleus.

Birk UJ, Baddeley D, Cremer C.

Methods Mol Biol. 2009;464:389-401. doi: 10.1007/978-1-60327-461-6_21.

PMID:
18951196
38.

High precision size measurement of centromere 8 and the 8q24/c-myc gene region in metaphase and interphase human fibroblasts indicate differential condensation.

Batram C, Baddeley D, Kreth G, Cremer C.

J Struct Biol. 2008 Dec;164(3):293-303. doi: 10.1016/j.jsb.2008.09.002. Epub 2008 Sep 19.

PMID:
18835450
39.

Spatial quantitative analysis of fluorescently labeled nuclear structures: problems, methods, pitfalls.

Ronneberger O, Baddeley D, Scheipl F, Verveer PJ, Burkhardt H, Cremer C, Fahrmeir L, Cremer T, Joffe B.

Chromosome Res. 2008;16(3):523-62. doi: 10.1007/s10577-008-1236-4. Review.

PMID:
18461488
40.

High-precision structural analysis of subnuclear complexes in fixed and live cells via spatially modulated illumination (SMI) microscopy.

Reymann J, Baddeley D, Gunkel M, Lemmer P, Stadter W, Jegou T, Rippe K, Cremer C, Birk U.

Chromosome Res. 2008;16(3):367-82. doi: 10.1007/s10577-008-1238-2.

PMID:
18461478
41.

Nanostructure analysis using spatially modulated illumination microscopy.

Baddeley D, Batram C, Weiland Y, Cremer C, Birk UJ.

Nat Protoc. 2007;2(10):2640-6.

PMID:
17948007
42.

4Pi microscopy deconvolution with a variable point-spread function.

Baddeley D, Carl C, Cremer C.

Appl Opt. 2006 Sep 20;45(27):7056-64.

PMID:
16946784
43.

Nanostructure of specific chromatin regions and nuclear complexes.

Mathée H, Baddeley D, Wotzlaw C, Fandrey J, Cremer C, Birk U.

Histochem Cell Biol. 2006 Jan;125(1-2):75-82. Epub 2005 Nov 12.

PMID:
16284774
44.

Reduced quality of clot formation with gelatin-based plasma substitutes.

Mardel SN, Saunders FM, Allen H, Menezes G, Edwards CM, Ollerenshaw L, Baddeley D, Kennedy A, Ibbotson RM.

Br J Anaesth. 1998 Feb;80(2):204-7.

45.

Clot formation and gelatin-based plasma substitutes.

Baddeley DT, Saunders FM, Ollerenshaw L, Edwards CM.

Lancet. 1996 Jun 22;347(9017):1763. No abstract available.

PMID:
8656920
46.

Reduced quality of in-vitro clot formation with gelatin-based plasma substitutes.

Mardel SN, Saunders F, Ollerenshaw L, Edwards C, Baddeley D.

Lancet. 1996 Mar 23;347(9004):825. No abstract available.

PMID:
8622348

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