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Items: 1 to 50 of 148

1.

Quantitation of α-hydroxy acids in complex prebiotic mixtures via liquid chromatography/tandem mass spectrometry.

Parker ET, Cleaves HJ 2nd, Bada JL, Fernández FM.

Rapid Commun Mass Spectrom. 2016 Sep 30;30(18):2043-51. doi: 10.1002/rcm.7684.

PMID:
27467333
2.

Is formamide a geochemically plausible prebiotic solvent?

Bada JL, Chalmers JH, Cleaves HJ.

Phys Chem Chem Phys. 2016 Jul 27;18(30):20085-90. doi: 10.1039/c6cp03290g.

PMID:
27253848
3.

On the lack of evolutionary continuity between prebiotic peptides and extant enzymes.

Raggi L, Bada JL, Lazcano A.

Phys Chem Chem Phys. 2016 Jul 27;18(30):20028-32. doi: 10.1039/c6cp00793g.

PMID:
27121024
4.

Ab initio simulations and the Miller prebiotic synthesis experiment.

Bada JL, Cleaves HJ 2nd.

Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):E342. doi: 10.1073/pnas.1420577112. Epub 2015 Jan 8. No abstract available.

5.

A plausible simultaneous synthesis of amino acids and simple peptides on the primordial Earth.

Parker ET, Zhou M, Burton AS, Glavin DP, Dworkin JP, Krishnamurthy R, Fernández FM, Bada JL.

Angew Chem Int Ed Engl. 2014 Jul 28;53(31):8132-6. doi: 10.1002/anie.201403683. Epub 2014 Jun 25.

PMID:
24966137
6.

Conducting miller-urey experiments.

Parker ET, Cleaves JH, Burton AS, Glavin DP, Dworkin JP, Zhou M, Bada JL, Fernández FM.

J Vis Exp. 2014 Jan 21;(83):e51039. doi: 10.3791/51039.

7.

Does aspartic acid racemization constrain the depth limit of the subsurface biosphere?

Onstott TC, Magnabosco C, Aubrey AD, Burton AS, Dworkin JP, Elsila JE, Grunsfeld S, Cao BH, Hein JE, Glavin DP, Kieft TL, Silver BJ, Phelps TJ, van Heerden E, Opperman DJ, Bada JL.

Geobiology. 2014 Jan;12(1):1-19. doi: 10.1111/gbi.12069. Epub 2013 Dec 2.

PMID:
24289240
8.

New insights into prebiotic chemistry from Stanley Miller's spark discharge experiments.

Bada JL.

Chem Soc Rev. 2013 Mar 7;42(5):2186-96. doi: 10.1039/c3cs35433d. Epub 2013 Jan 22. Review.

PMID:
23340907
9.

Desorption electrospray ionization imaging mass spectrometry as a tool for investigating model prebiotic reactions on mineral surfaces.

Bennett RV, Cleaves HJ 2nd, Davis JM, Sokolov DA, Orlando TM, Bada JL, Fernández FM.

Anal Chem. 2013 Feb 5;85(3):1276-9. doi: 10.1021/ac303202n. Epub 2013 Jan 10.

PMID:
23286321
10.

Inconclusive evidence for nonterrestrial isoleucine enantiomeric excesses in primitive meteorites.

Elsila JE, Glavin DP, Dworkin JP, Martins Z, Bada JL.

Proc Natl Acad Sci U S A. 2012 Nov 27;109(48):E3288; author reply E3289. doi: 10.1073/pnas.1213261109. Epub 2012 Oct 12. No abstract available.

11.

Curiosity and contamination.

Bada JL.

Science. 2012 Sep 28;337(6102):1604. No abstract available.

PMID:
23019627
12.

Enhanced synthesis of alkyl amino acids in Miller's 1958 H2S experiment.

Parker ET, Cleaves HJ, Callahan MP, Dworkin JP, Glavin DP, Lazcano A, Bada JL.

Orig Life Evol Biosph. 2011 Dec;41(6):569-74. doi: 10.1007/s11084-011-9253-2. Epub 2011 Dec 3.

PMID:
22139514
13.

Primordial ocean chemistry and its compatibility with the RNA world.

Kua J, Bada JL.

Orig Life Evol Biosph. 2011 Dec;41(6):553-8. doi: 10.1007/s11084-011-9250-5. Epub 2011 Dec 3.

PMID:
22139511
14.

Unexamined bodies of evidence.

Schoeninger MJ, Bada JL, Masters PM, Bettinger RL, White TD.

Science. 2011 May 20;332(6032):916. doi: 10.1126/science.332.6032.916-a. No abstract available.

PMID:
21596975
15.

Metalloproteins and the pyrite-based origin of life: a critical assessment.

Rivas M, Becerra A, Peretó J, Bada JL, Lazcano A.

Orig Life Evol Biosph. 2011 Aug;41(4):347-56. doi: 10.1007/s11084-011-9238-1. Epub 2011 Mar 24.

PMID:
21431891
16.

Primordial synthesis of amines and amino acids in a 1958 Miller H2S-rich spark discharge experiment.

Parker ET, Cleaves HJ, Dworkin JP, Glavin DP, Callahan M, Aubrey A, Lazcano A, Bada JL.

Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5526-31. doi: 10.1073/pnas.1019191108. Epub 2011 Mar 21.

17.

Borate minerals and origin of the RNA world.

Grew ES, Bada JL, Hazen RM.

Orig Life Evol Biosph. 2011 Aug;41(4):307-16. doi: 10.1007/s11084-010-9233-y. Epub 2011 Jan 8.

PMID:
21221809
18.

Prebiotic synthesis of methionine and other sulfur-containing organic compounds on the primitive Earth: a contemporary reassessment based on an unpublished 1958 Stanley Miller experiment.

Parker ET, Cleaves HJ, Callahan MP, Dworkin JP, Glavin DP, Lazcano A, Bada JL.

Orig Life Evol Biosph. 2011 Jun;41(3):201-12. doi: 10.1007/s11084-010-9228-8. Epub 2010 Nov 10.

19.

Enantiomeric excesses in the Murchison meteorite and the origin of homochirality in terrestrial biology.

Bada JL.

Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):E85; author reply E86. doi: 10.1073/pnas.0906490106. Epub 2009 Jul 30. No abstract available.

20.

Charles Darwin and the origin of life.

Peretó J, Bada JL, Lazcano A.

Orig Life Evol Biosph. 2009 Oct;39(5):395-406. doi: 10.1007/s11084-009-9172-7. Epub 2009 Jul 25.

21.

An evaluation of the critical parameters for abiotic peptide synthesis in submarine hydrothermal systems.

Cleaves HJ, Aubrey AD, Bada JL.

Orig Life Evol Biosph. 2009 Apr;39(2):109-26. doi: 10.1007/s11084-008-9154-1. Epub 2008 Nov 27.

PMID:
19037745
22.

The role of submarine hydrothermal systems in the synthesis of amino acids.

Aubrey AD, Cleaves HJ, Bada JL.

Orig Life Evol Biosph. 2009 Apr;39(2):91-108. doi: 10.1007/s11084-008-9153-2. Epub 2008 Nov 26.

PMID:
19034685
23.

The Miller volcanic spark discharge experiment.

Johnson AP, Cleaves HJ, Dworkin JP, Glavin DP, Lazcano A, Bada JL.

Science. 2008 Oct 17;322(5900):404. doi: 10.1126/science.1161527.

24.

Stanley L. Miller (1930--2007): reflections and remembrances.

Lazcano A, Bada JL.

Orig Life Evol Biosph. 2008 Oct;38(5):373-81. doi: 10.1007/s11084-008-9145-2. Epub 2008 Aug 26.

PMID:
18726708
25.

The Urey instrument: an advanced in situ organic and oxidant detector for Mars exploration.

Aubrey AD, Chalmers JH, Bada JL, Grunthaner FJ, Amashukeli X, Willis P, Skelley AM, Mathies RA, Quinn RC, Zent AP, Ehrenfreund P, Amundson R, Glavin DP, Botta O, Barron L, Blaney DL, Clark BC, Coleman M, Hofmann BA, Josset JL, Rettberg P, Ride S, Robert F, Sephton MA, Yen A.

Astrobiology. 2008 Jun;8(3):583-95. doi: 10.1089/ast.2007.0169.

PMID:
18680409
26.

A reassessment of prebiotic organic synthesis in neutral planetary atmospheres.

Cleaves HJ, Chalmers JH, Lazcano A, Miller SL, Bada JL.

Orig Life Evol Biosph. 2008 Apr;38(2):105-15. doi: 10.1007/s11084-007-9120-3. Epub 2008 Jan 19.

PMID:
18204914
27.

Stable isotopes, ecological integration and environmental change: wolves record atmospheric carbon isotope trend better than tree rings.

Bump JK, Fox-Dobbs K, Bada JL, Koch PL, Peterson RO, Vucetich JA.

Proc Biol Sci. 2007 Oct 7;274(1624):2471-80.

28.

Debating evidence for the origin of life on Earth.

Bada JL, Fegley B Jr, Miller SL, Lazcano A, Cleaves HJ, Hazen RM, Chalmers J.

Science. 2007 Feb 16;315(5814):937-9; author reply 937-9. No abstract available.

PMID:
17303735
29.

Application of the Mars Organic Analyzer to nucleobase and amine biomarker detection.

Skelley AM, Cleaves HJ, Jayarajah CN, Bada JL, Mathies RA.

Astrobiology. 2006 Dec;6(6):824-37.

PMID:
17155883
30.

Don't dismiss astrobiology. Response.

Bada JL.

Science. 2005 Apr 22;308(5721):495-7. No abstract available.

PMID:
15849862
31.

Development and evaluation of a microdevice for amino acid biomarker detection and analysis on Mars.

Skelley AM, Scherer JR, Aubrey AD, Grover WH, Ivester RH, Ehrenfreund P, Grunthaner FJ, Bada JL, Mathies RA.

Proc Natl Acad Sci U S A. 2005 Jan 25;102(4):1041-6. Epub 2005 Jan 18.

32.

New method for estimating bacterial cell abundances in natural samples by use of sublimation.

Glavin DP, Cleaves HJ, Schubert M, Aubrey A, Bada JL.

Appl Environ Microbiol. 2004 Oct;70(10):5923-8.

33.

The 1953 Stanley L. Miller experiment: fifty years of prebiotic organic chemistry.

Lazcano A, Bada JL.

Orig Life Evol Biosph. 2003 Jun;33(3):235-42. No abstract available.

PMID:
14515862
34.
35.

Perceptions of science. Prebiotic soup--revisiting the Miller experiment.

Bada JL, Lazcano A.

Science. 2003 May 2;300(5620):745-6.

36.

Direct isolation of purines and pyrimidines from nucleic acids using sublimation.

Glavin DP, Schubert M, Bada JL.

Anal Chem. 2002 Dec 15;74(24):6408-12.

PMID:
12510767
37.

Survival of amino acids in micrometeorites during atmospheric entry.

Glavin DP, Bada JL.

Astrobiology. 2001 Fall;1(3):259-69.

PMID:
12448989
38.

Relative amino acid concentrations as a signature for parent body processes of carbonaceous chondrites.

Botta O, Glavin DP, Kminek G, Bada JL.

Orig Life Evol Biosph. 2002 Apr;32(2):143-63.

PMID:
12185673
39.

Origin of life. Some like it hot, but not the first biomolecules.

Bada JL, Lazcano A.

Science. 2002 Jun 14;296(5575):1982-3. No abstract available.

PMID:
12065824
40.

Miller revealed new ways to study the origins of life.

Bada JL, Lazcano A.

Nature. 2002 Apr 4;416(6880):475. No abstract available.

PMID:
11932715
41.

Prebiotic synthesis of adenine and amino acids under Europa-like conditions.

Levy M, Miller SL, Brinton K, Bada JL.

Icarus. 2000 Jun;145(2):609-13.

PMID:
11543508
42.

The origin of organic matter in the Martian meteorite ALH84001.

Becker L, Popp B, Rust T, Bada JL.

Adv Space Res. 1999;24(4):477-88.

PMID:
11543335
43.

The origin of organic matter in the Martian meteorite ALH84001.

Becker L, Popp B, Rust T, Bada JL.

Earth Planet Sci Lett. 1999 Mar 30;167(1-2):71-9.

PMID:
11542930
44.

Extraterrestrial amino acids in Orgueil and Ivuna: tracing the parent body of CI type carbonaceous chondrites.

Ehrenfreund P, Glavin DP, Botta O, Cooper G, Bada JL.

Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2138-41.

45.

State-of-the-art instruments for detecting extraterrestrial life.

Bada JL.

Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):797-800. Review. No abstract available.

46.

Isolation of amino acids from natural samples using sublimation.

Glavin DP, Bada JL.

Anal Chem. 1998 Aug 1;70(15):3119-22.

PMID:
11013716
47.

[Differential characteristics of AIDS in foreign immigrants].

García de Olalla P, Lai A, Jansà JM, Bada JL, Caylà JA.

Gac Sanit. 2000 May-Jun;14(3):189-94. Spanish.

48.

Microfabricated capillary electrophoresis amino acid chirality analyzer for extraterrestrial exploration.

Hutt LD, Glavin DP, Bada JL, Mathies RA.

Anal Chem. 1999 Sep 15;71(18):4000-6.

PMID:
10500487
49.

Amino acids in the Martian meteorite Nakhla.

Glavin DP, Bada JL, Brinton KL, McDonald GD.

Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8835-8.

50.

[Tuberculosis in immigrants recently arrived in Barcelona].

Saravanja M, Terre M, Ros M, Bada JL.

Med Clin (Barc). 1999 Mar 13;112(9):359. Spanish. No abstract available.

PMID:
10220773

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