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Items: 1 to 50 of 211

1.

Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging.

Winkelmann JA, Eid A, Spicer G, Almassalha LM, Nguyen TQ, Backman V.

Light Sci Appl. 2019 Jan 16;8:7. doi: 10.1038/s41377-018-0117-7. eCollection 2019.

2.

Sub-10-nm imaging of nucleic acids using spectroscopic intrinsic-contrast photon-localization optical nanoscopy (SICLON).

Eshein A, Li Y, Dong B, Almassalha LM, Chandler JE, Nguyen TQ, Hujsak KA, Dravid VP, Sun C, Zhang HF, Backman V.

Opt Lett. 2018 Dec 1;43(23):5817-5820. doi: 10.1364/OL.43.005817.

3.

Label free localization of nanoparticles in live cancer cells using spectroscopic microscopy.

Spicer GLC, Almassalha L, Martinez IA, Ellis R, Chandler JE, Gladstein S, Zhang D, Nguyen TQ, Feder S, Subramanian H, de la Rica R, Thompson SA, Backman V.

Nanoscale. 2018 Oct 18;10(40):19125-19130. doi: 10.1039/c8nr07481j.

PMID:
30298892
4.

Early increase in blood supply (EIBS) is associated with tumor risk in the Azoxymethane model of colon cancer.

Ruderman S, Eshein A, Valuckaite V, Dougherty U, Almoghrabi A, Gomes A, Singh A, Pabla B, Roy HK, Hart J, Bissonnette M, Konda V, Backman V.

BMC Cancer. 2018 Aug 13;18(1):814. doi: 10.1186/s12885-018-4709-7.

5.

Correction: Biophotonic detection of high order chromatin alterations in field carcinogenesis predicts risk of future hepatocellular carcinoma: A pilot study.

Kalman RS, Stawarz A, Nunes D, Zhang D, Dela Cruz MA, Mohanty A, Subramanian H, Backman V, Roy HK.

PLoS One. 2018 Jul 24;13(7):e0201500. doi: 10.1371/journal.pone.0201500. eCollection 2018.

6.

Fully automated fiber-based optical spectroscopy system for use in a clinical setting.

Eshein A, Radosevich A, Gould B, Wu W, Konda V, Yang L, Koons A, Feder S, Valuckaite V, Roy H, Backman V, Nguyen TQ.

J Biomed Opt. 2018 Jul;23(7):1-10. doi: 10.1117/1.JBO.23.7.075003.

PMID:
29981224
7.

Biophotonic detection of high order chromatin alterations in field carcinogenesis predicts risk of future hepatocellular carcinoma: A pilot study.

Kalman RS, Stawarz A, Nunes D, Zhang D, Dela Cruz MA, Mohanty A, Subramanian H, Backman V, Roy HK.

PLoS One. 2018 May 17;13(5):e0197427. doi: 10.1371/journal.pone.0197427. eCollection 2018. Erratum in: PLoS One. 2018 Jul 24;13(7):e0201500.

8.

Correlating colorectal cancer risk with field carcinogenesis progression using partial wave spectroscopic microscopy.

Gladstein S, Damania D, Almassalha LM, Smith LT, Gupta V, Subramanian H, Rex DK, Roy HK, Backman V.

Cancer Med. 2018 May;7(5):2109-2120. doi: 10.1002/cam4.1357. Epub 2018 Mar 23.

9.

Measuring Nanoscale Chromatin Heterogeneity with Partial Wave Spectroscopic Microscopy.

Gladstein S, Stawarz A, Almassalha LM, Cherkezyan L, Chandler JE, Zhou X, Subramanian H, Backman V.

Methods Mol Biol. 2018;1745:337-360. doi: 10.1007/978-1-4939-7680-5_19.

10.

Single Nucleotide Polymorphism Facilitated Down-Regulation of the Cohesin Stromal Antigen-1: Implications for Colorectal Cancer Racial Disparities.

Datta S, Sherva RM, De La Cruz M, Long MT, Roy P, Backman V, Chowdhury S, Roy HK.

Neoplasia. 2018 Mar;20(3):289-294. doi: 10.1016/j.neo.2018.01.003. Epub 2018 Feb 19.

11.

Macrogenomic engineering via modulation of the scaling of chromatin packing density.

Almassalha LM, Bauer GM, Wu W, Cherkezyan L, Zhang D, Kendra A, Gladstein S, Chandler JE, VanDerway D, Seagle BL, Ugolkov A, Billadeau DD, O'Halloran TV, Mazar AP, Roy HK, Szleifer I, Shahabi S, Backman V.

Nat Biomed Eng. 2017 Nov;1(11):902-913. doi: 10.1038/s41551-017-0153-2. Epub 2017 Nov 6.

12.

In vivo broadband visible light optical coherence tomography probe enables inverse spectroscopic analysis.

Winkelmann JA, Eid A, Nguyen TQ, Bui T, Yi J, Backman V.

Opt Lett. 2018 Feb 1;43(3):619-622. doi: 10.1364/OL.43.000619.

PMID:
29400855
13.

Chromatin histone modifications and rigidity affect nuclear morphology independent of lamins.

Stephens AD, Liu PZ, Banigan EJ, Almassalha LM, Backman V, Adam SA, Goldman RD, Marko JF.

Mol Biol Cell. 2018 Jan 15;29(2):220-233. doi: 10.1091/mbc.E17-06-0410. Epub 2017 Nov 15.

14.

Bleaching response of coral species in the context of assemblage response.

Swain TD, DuBois E, Goldberg SJ, Backman V, Marcelino LA.

Coral Reefs. 2017 Jun;36(2):395-400. doi: 10.1007/s00338-017-1550-4. Epub 2017 Jan 27.

15.

The transformation of the nuclear nanoarchitecture in human field carcinogenesis.

Bauer GM, Stypula-Cyrus Y, Subramanian H, Cherkezyan L, Viswanathan P, Zhang D, Iyengar R, Bagalkar S, Derbas J, Graff T, Gladstein S, Almassalha LM, Chandler JE, Roy HK, Backman V.

Future Sci OA. 2017 May 5;3(3):FSO206. doi: 10.4155/fsoa-2017-0027. eCollection 2017 Aug. Review.

16.

The effects of chemical fixation on the cellular nanostructure.

Li Y, Almassalha LM, Chandler JE, Zhou X, Stypula-Cyrus YE, Hujsak KA, Roth EW, Bleher R, Subramanian H, Szleifer I, Dravid VP, Backman V.

Exp Cell Res. 2017 Sep 15;358(2):253-259. doi: 10.1016/j.yexcr.2017.06.022. Epub 2017 Jun 30.

17.

Metabolic reprogramming of the premalignant colonic mucosa is an early event in carcinogenesis.

Cruz MD, Ledbetter S, Chowdhury S, Tiwari AK, Momi N, Wali RK, Bliss C, Huang C, Lichtenstein D, Bhattacharya S, Varma-Wilson A, Backman V, Roy HK.

Oncotarget. 2017 Mar 28;8(13):20543-20557. doi: 10.18632/oncotarget.16129.

18.

Measuring the Autocorrelation Function of Nanoscale Three-Dimensional Density Distribution in Individual Cells Using Scanning Transmission Electron Microscopy, Atomic Force Microscopy, and a New Deconvolution Algorithm.

Li Y, Zhang D, Capoglu I, Hujsak KA, Damania D, Cherkezyan L, Roth E, Bleher R, Wu JS, Subramanian H, Dravid VP, Backman V.

Microsc Microanal. 2017 Jun;23(3):661-667. doi: 10.1017/S1431927617000447. Epub 2017 Apr 18.

19.

Stochastic fluorescence switching of nucleic acids under visible light illumination.

Dong B, Almassalha LM, Soetikno BT, Chandler JE, Nguyen TQ, Urban BE, Sun C, Zhang HF, Backman V.

Opt Express. 2017 Apr 3;25(7):7929-7944. doi: 10.1364/OE.25.007929.

20.

Review of interferometric spectroscopy of scattered light for the quantification of subdiffractional structure of biomaterials.

Cherkezyan L, Zhang D, Subramanian H, Capoglu I, Taflove A, Backman V.

J Biomed Opt. 2017 Mar 1;22(3):30901. doi: 10.1117/1.JBO.22.3.030901. Review.

21.

Theoretical model for optical oximetry at the capillary level: exploring hemoglobin oxygen saturation through backscattering of single red blood cells.

Liu R, Spicer G, Chen S, Zhang HF, Yi J, Backman V.

J Biomed Opt. 2017 Feb 1;22(2):25002. doi: 10.1117/1.JBO.22.2.025002.

22.

ASPirin Intervention for the REDuction of colorectal cancer risk (ASPIRED): a study protocol for a randomized controlled trial.

Drew DA, Chin SM, Gilpin KK, Parziale M, Pond E, Schuck MM, Stewart K, Flagg M, Rawlings CA, Backman V, Carolan PJ, Chung DC, Colizzo FP 3rd, Freedman M, Gala M, Garber JJ, Huttenhower C, Kedrin D, Khalili H, Kwon DS, Markowitz SD, Milne GL, Nishioka NS, Richter JM, Roy HK, Staller K, Wang M, Chan AT.

Trials. 2017 Feb 1;18(1):50. doi: 10.1186/s13063-016-1744-z.

23.

The Global Relationship between Chromatin Physical Topology, Fractal Structure, and Gene Expression.

Almassalha LM, Tiwari A, Ruhoff PT, Stypula-Cyrus Y, Cherkezyan L, Matsuda H, Dela Cruz MA, Chandler JE, White C, Maneval C, Subramanian H, Szleifer I, Roy HK, Backman V.

Sci Rep. 2017 Jan 24;7:41061. doi: 10.1038/srep41061.

24.

Using electron microscopy to calculate optical properties of biological samples.

Wu W, Radosevich AJ, Eshein A, Nguyen TQ, Yi J, Cherkezyan L, Roy HK, Szleifer I, Backman V.

Biomed Opt Express. 2016 Oct 27;7(11):4749-4762. eCollection 2016 Nov 1.

25.

Higher Order Chromatin Modulator Cohesin SA1 Is an Early Biomarker for Colon Carcinogenesis: Race-Specific Implications.

Wali RK, Momi N, Dela Cruz M, Calderwood AH, Stypula-Cyrus Y, Almassalha L, Chhaparia A, Weber CR, Radosevich A, Tiwari AK, Latif B, Backman V, Roy HK.

Cancer Prev Res (Phila). 2016 Nov;9(11):844-854. Epub 2016 Aug 22.

26.

Label-free imaging of the native, living cellular nanoarchitecture using partial-wave spectroscopic microscopy.

Almassalha LM, Bauer GM, Chandler JE, Gladstein S, Cherkezyan L, Stypula-Cyrus Y, Weinberg S, Zhang D, Thusgaard Ruhoff P, Roy HK, Subramanian H, Chandel NS, Szleifer I, Backman V.

Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):E6372-E6381. Epub 2016 Oct 4.

27.

Optical Detection of Early Damage in Retinal Ganglion Cells in a Mouse Model of Partial Optic Nerve Crush Injury.

Yi J, Puyang Z, Feng L, Duan L, Liang P, Backman V, Liu X, Zhang HF.

Invest Ophthalmol Vis Sci. 2016 Oct 1;57(13):5665-5671. doi: 10.1167/iovs.16-19955.

28.

Procedures for risk-stratification of lung cancer using buccal nanocytology.

Subramanian H, Viswanathan P, Cherkezyan L, Iyengar R, Rozhok S, Verleye M, Derbas J, Czarnecki J, Roy HK, Backman V.

Biomed Opt Express. 2016 Aug 31;7(9):3795-3810. eCollection 2016 Sep 1.

29.

Enhancing the sensitivity of mesoscopic light reflection statistics in weakly disordered media by interface reflections.

Park DJ, Pradhan P, Backman V.

Int J Mod Phys B. 2016 Sep 20;30(23). pii: 1650155. doi: 10.1142/S0217979216501551. Epub 2016 Jul 29.

30.

Enhanced Survival with Implantable Scaffolds That Capture Metastatic Breast Cancer Cells In Vivo.

Rao SS, Bushnell GG, Azarin SM, Spicer G, Aguado BA, Stoehr JR, Jiang EJ, Backman V, Shea LD, Jeruss JS.

Cancer Res. 2016 Sep 15;76(18):5209-18. doi: 10.1158/0008-5472.CAN-15-2106.

31.

Detection of extracellular matrix modification in cancer models with inverse spectroscopic optical coherence tomography.

Spicer GL, Azarin SM, Yi J, Young ST, Ellis R, Bauer GM, Shea LD, Backman V.

Phys Med Biol. 2016 Oct 7;61(19):6892-6904. Epub 2016 Sep 12.

32.

The Greater Genomic Landscape: The Heterogeneous Evolution of Cancer.

Almassalha LM, Bauer GM, Chandler JE, Gladstein S, Szleifer I, Roy HK, Backman V.

Cancer Res. 2016 Oct 1;76(19):5605-5609. Epub 2016 Aug 22.

33.

Superresolution intrinsic fluorescence imaging of chromatin utilizing native, unmodified nucleic acids for contrast.

Dong B, Almassalha LM, Stypula-Cyrus Y, Urban BE, Chandler JE, Nguyen TQ, Sun C, Zhang HF, Backman V.

Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9716-21. doi: 10.1073/pnas.1602202113. Epub 2016 Aug 17.

34.

Super-resolution spectroscopic microscopy via photon localization.

Dong B, Almassalha L, Urban BE, Nguyen TQ, Khuon S, Chew TL, Backman V, Sun C, Zhang HF.

Nat Commun. 2016 Jul 25;7:12290. doi: 10.1038/ncomms12290.

35.

Subsurface Super-resolution Imaging of Unstained Polymer Nanostructures.

Urban BE, Dong B, Nguyen TQ, Backman V, Sun C, Zhang HF.

Sci Rep. 2016 Jun 29;6:28156. doi: 10.1038/srep28156.

36.

Finite-difference time-domain-based optical microscopy simulation of dispersive media facilitates the development of optical imaging techniques.

Zhang D, Capoglu I, Li Y, Cherkezyan L, Chandler J, Spicer G, Subramanian H, Taflove A, Backman V.

J Biomed Opt. 2016 Jun 1;21(6):65004. doi: 10.1117/1.JBO.21.6.065004.

37.

Nanoscale refractive index fluctuations detected via sparse spectral microscopy.

Chandler JE, Cherkezyan L, Subramanian H, Backman V.

Biomed Opt Express. 2016 Feb 19;7(3):883-93. doi: 10.1364/BOE.7.000883. eCollection 2016 Mar 1.

38.

Colocalization of cellular nanostructure using confocal fluorescence and partial wave spectroscopy.

Chandler JE, Stypula-Cyrus Y, Almassalha L, Bauer G, Bowen L, Subramanian H, Szleifer I, Backman V.

J Biophotonics. 2017 Mar;10(3):377-384. doi: 10.1002/jbio.201500298. Epub 2016 Apr 25.

39.

Coral bleaching response index: a new tool to standardize and compare susceptibility to thermal bleaching.

Swain TD, Vega-Perkins JB, Oestreich WK, Triebold C, DuBois E, Henss J, Baird A, Siple M, Backman V, Marcelino L.

Glob Chang Biol. 2016 Jul;22(7):2475-88. doi: 10.1111/gcb.13276. Epub 2016 Apr 13.

40.

Skeletal light-scattering accelerates bleaching response in reef-building corals.

Swain TD, DuBois E, Gomes A, Stoyneva VP, Radosevich AJ, Henss J, Wagner ME, Derbas J, Grooms HW, Velazquez EM, Traub J, Kennedy BJ, Grigorescu AA, Westneat MW, Sanborn K, Levine S, Schick M, Parsons G, Biggs BC, Rogers JD, Backman V, Marcelino LA.

BMC Ecol. 2016 Mar 21;16:10. doi: 10.1186/s12898-016-0061-4.

41.

Automated Cell Selection Using Support Vector Machine for Application to Spectral Nanocytology.

Miao Q, Derbas J, Eid A, Subramanian H, Backman V.

Biomed Res Int. 2016;2016:6090912. doi: 10.1155/2016/6090912. Epub 2016 Jan 19.

42.

Reconstruction of explicit structural properties at the nanoscale via spectroscopic microscopy.

Cherkezyan L, Zhang D, Subramanian H, Taflove A, Backman V.

J Biomed Opt. 2016 Feb;21(2):25007. doi: 10.1117/1.JBO.21.2.025007.

43.

Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation.

Yi J, Liu W, Chen S, Backman V, Sheibani N, Sorenson CM, Fawzi AA, Linsenmeier RA, Zhang HF.

Light Sci Appl. 2015 Sep;4(9). pii: e334. Epub 2015 Sep 25.

44.

Fractal Characterization of Chromatin Decompaction in Live Cells.

Yi J, Stypula-Cyrus Y, Blaha CS, Roy HK, Backman V.

Biophys J. 2015 Dec 1;109(11):2218-26. doi: 10.1016/j.bpj.2015.10.014.

45.

Spectroscopic microscopy can quantify the statistics of subdiffractional refractive-index fluctuations in media with random rough surfaces.

Zhang D, Cherkezyan L, Capoglu I, Subramanian H, Chandler J, Thompson S, Taflove A, Backman V.

Opt Lett. 2015 Nov 1;40(21):4931-4. doi: 10.1364/OL.40.004931.

46.

Spectral biomarkers for chemoprevention of colonic neoplasia: a placebo-controlled double-blinded trial with aspirin.

Roy HK, Turzhitsky V, Wali R, Radosevich AJ, Jovanovic B, Della'Zanna G, Umar A, Rubin DT, Goldberg MJ, Bianchi L, De La Cruz M, Bogojevic A, Helenowski IB, Rodriguez L, Chatterton R, Skripkauskas S, Page K, Weber CR, Huang X, Richmond E, Bergan RC, Backman V.

Gut. 2017 Feb;66(2):285-292. doi: 10.1136/gutjnl-2015-309996. Epub 2015 Oct 26.

47.

Clinical Trial Laboratory Data Nested With in Subject: Components of Variance, Sample Size and Cost.

Jovanovic BD, Subramanian H, Helenowski IB, Roy HK, Backman V.

Biom Biostat Int J. 2015;2(3). pii: 00029. Epub 2015 Apr 15.

48.

Subdiffusion reflectance spectroscopy to measure tissue ultrastructure and microvasculature: model and inverse algorithm.

Radosevich AJ, Eshein A, Nguyen TQ, Backman V.

J Biomed Opt. 2015;20(9):097002. doi: 10.1117/1.JBO.20.9.097002.

49.

Harnessing novel modalities: field carcinogenesis detection for personalizing prostate cancer management.

Momi N, Backman V, Brendler CB, Roy HK.

Future Oncol. 2015;11(20):2737-41. doi: 10.2217/fon.15.182. Epub 2015 Sep 16. No abstract available.

50.

In vivo capture and label-free detection of early metastatic cells.

Azarin SM, Yi J, Gower RM, Aguado BA, Sullivan ME, Goodman AG, Jiang EJ, Rao SS, Ren Y, Tucker SL, Backman V, Jeruss JS, Shea LD.

Nat Commun. 2015 Sep 8;6:8094. doi: 10.1038/ncomms9094.

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