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Comparison of initial oral microbiomes of young adults with and without cavitated dentin caries lesions using an in situ biofilm model.

Rupf S, Laczny CC, Galata V, Backes C, Keller A, Umanskaya N, Erol A, Tierling S, Lo Porto C, Walter J, Kirsch J, Hannig M, Hannig C.

Sci Rep. 2018 Sep 18;8(1):14010. doi: 10.1038/s41598-018-32361-x.


Natural killer cells induce distinct modes of cancer cell death: Discrimination, quantification, and modulation of apoptosis, necrosis, and mixed forms.

Backes CS, Friedmann KS, Mang S, Knörck A, Hoth M, Kummerow C.

J Biol Chem. 2018 Oct 19;293(42):16348-16363. doi: 10.1074/jbc.RA118.004549. Epub 2018 Sep 6.


MicroRNA in diagnosis and therapy monitoring of early-stage triple-negative breast cancer.

Kahraman M, Röske A, Laufer T, Fehlmann T, Backes C, Kern F, Kohlhaas J, Schrörs H, Saiz A, Zabler C, Ludwig N, Fasching PA, Strick R, Rübner M, Beckmann MW, Meese E, Keller A, Schrauder MG.

Sci Rep. 2018 Aug 2;8(1):11584. doi: 10.1038/s41598-018-29917-2.


Molecular chemistry approaches for tuning the properties of two-dimensional transition metal dichalcogenides.

Bertolazzi S, Gobbi M, Zhao Y, Backes C, Samorì P.

Chem Soc Rev. 2018 Aug 28;47(17):6845-6888. doi: 10.1039/c8cs00169c. Review.


Revert to the original: time to re-establish delayed umbilical cord clamping as the standard approach for preterm neonates.

McAdams RM, Backes CH, Fathi O, Hutchon DJR.

Matern Health Neonatol Perinatol. 2018 Jul 4;4:13. doi: 10.1186/s40748-018-0081-5. eCollection 2018.


Genome-wide MicroRNA Expression Profiles in COPD: Early Predictors for Cancer Development.

Keller A, Fehlmann T, Ludwig N, Kahraman M, Laufer T, Backes C, Vogelmeier C, Diener C, Biertz F, Herr C, Jörres RA, Lenhof HP, Meese E, Bals R; COSYCONET Study Group.

Genomics Proteomics Bioinformatics. 2018 Jun;16(3):162-171. doi: 10.1016/j.gpb.2018.06.001. Epub 2018 Jul 5.


The nursing team's performance towards the sexuality of institutionalized elderly women.

Venturini L, Beuter M, Leite MT, Bruinsma JL, Backes C.

Rev Esc Enferm USP. 2018 Jun 25;52:e03302. doi: 10.1590/S1980-220X2017017903302. Portuguese, English, Spanish.


Catheter-based closure of the patent ductus arteriosus in lower weight infants.

Pavlek LR, Slaughter JL, Berman DP, Backes CH.

Semin Perinatol. 2018 Jun;42(4):262-268. doi: 10.1053/j.semperi.2018.05.009. Epub 2018 Jun 13. Review.


Body Anatomical UV Protection Predicted by Shade Structures: A Modeling Study.

Religi A, Backes C, Moccozet L, Vuilleumier L, Vernez D, Bulliard JL.

Photochem Photobiol. 2018 Jun 7. doi: 10.1111/php.12949. [Epub ahead of print]


Long-lived photoluminescence polarization of localized excitons in liquid exfoliated monolayer enriched WS2.

Kłopotowski Ł, Czechowski N, Mitioglu AA, Backes C, Maude DK, Plochocka P.

Nanotechnology. 2018 Aug 17;29(33):335703. doi: 10.1088/1361-6528/aac73e. Epub 2018 May 23.


Extracorporeal Membrane Oxygenation Characteristics and Outcomes in Adult Patients With Down Syndrome.

Duffy V, Gomez D, Rycus P, Rivera B, Santoro SL, Backes CH, Cua CL.

Artif Organs. 2018 Sep;42(9):921-925. doi: 10.1111/aor.13160. Epub 2018 May 17.


The deterministic role of 5-mers in microRNA-gene targeting.

Hart M, Kern F, Backes C, Rheinheimer S, Fehlmann T, Keller A, Meese E.

RNA Biol. 2018;15(6):819-825. doi: 10.1080/15476286.2018.1462652. Epub 2018 May 11.


Small ncRNA-Seq Results of Human Tissues: Variations Depending on Sample Integrity.

Ludwig N, Fehlmann T, Galata V, Franke A, Backes C, Meese E, Keller A.

Clin Chem. 2018 Jul;64(7):1074-1084. doi: 10.1373/clinchem.2017.285767. Epub 2018 Apr 24.


Facial exposure to ultraviolet radiation: Predicted sun protection effectiveness of various hat styles.

Backes C, Religi A, Moccozet L, Vuilleumier L, Vernez D, Bulliard JL.

Photodermatol Photoimmunol Photomed. 2018 Sep;34(5):330-337. doi: 10.1111/phpp.12388. Epub 2018 May 31.


Biological recognition of graphene nanoflakes.

Castagnola V, Zhao W, Boselli L, Lo Giudice MC, Meder F, Polo E, Paton KR, Backes C, Coleman JN, Dawson KA.

Nat Commun. 2018 Apr 20;9(1):1577. doi: 10.1038/s41467-018-04009-x.


Pulmonary Vein Stenosis in Infants: A Systematic Review, Meta-Analysis, and Meta-Regression.

Backes CH, Nealon E, Armstrong AK, Cua CL, Mitchell C, Krishnan U, Vanderlaan RD, Song MK, Viola N, Smith CV, McConnell PI, Rivera BK, Bridge J.

J Pediatr. 2018 Jul;198:36-45.e3. doi: 10.1016/j.jpeds.2018.02.030. Epub 2018 Apr 9.


Short term evaluation of respiratory effort by premature infants supported with bubble nasal continuous airway pressure using Seattle-PAP and a standard bubble device.

Welty SE, Rusin CG, Stanberry LI, Mandy GT, Gest AL, Ford JM, Backes CH Jr, Richardson CP, Howard CR, Hansen TN, Smith CV.

PLoS One. 2018 Mar 28;13(3):e0193807. doi: 10.1371/journal.pone.0193807. eCollection 2018.


Differences in midterm outcomes in infants with hypoplastic left heart syndrome diagnosed with necrotizing enterocolitis: NPCQIC database analysis.

Lopez NL, Gowda C, Backes CH, Nandi D, Miller-Tate H, Fichtner S, Allen R, Stewart J, Cua CL.

Congenit Heart Dis. 2018 Jul;13(4):512-518. doi: 10.1111/chd.12602. Epub 2018 Mar 9.


Paediatric abstract publication rates for the American Society of Echocardiography Meeting.

Morrison A, Kelly J, Rivera B, Backes CH, Cua CL.

Cardiol Young. 2018 May;28(5):692-696. doi: 10.1017/S1047951118000033. Epub 2018 Feb 13.


A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity.

Zhou X, Friedmann KS, Lyrmann H, Zhou Y, Schoppmeyer R, Knörck A, Mang S, Hoxha C, Angenendt A, Backes CS, Mangerich C, Zhao R, Cappello S, Schwär G, Hässig C, Neef M, Bufe B, Zufall F, Kruse K, Niemeyer BA, Lis A, Qu B, Kummerow C, Schwarz EC, Hoth M.

J Physiol. 2018 Jul;596(14):2681-2698. doi: 10.1113/JP274964. Epub 2018 Mar 12.


Transcriptomic Analysis of Intestinal Tissues from Two 90-Day Feeding Studies in Rats Using Genetically Modified MON810 Maize Varieties.

Sharbati J, Bohmer M, Bohmer N, Keller A, Backes C, Franke A, Steinberg P, Zeljenková D, Einspanier R.

Front Genet. 2017 Dec 19;8:222. doi: 10.3389/fgene.2017.00222. eCollection 2017.


About miRNAs, miRNA seeds, target genes and target pathways.

Kehl T, Backes C, Kern F, Fehlmann T, Ludwig N, Meese E, Lenhof HP, Keller A.

Oncotarget. 2017 Nov 9;8(63):107167-107175. doi: 10.18632/oncotarget.22363. eCollection 2017 Dec 5.


A high-resolution map of the human small non-coding transcriptome.

Fehlmann T, Backes C, Alles J, Fischer U, Hart M, Kern F, Langseth H, Rounge T, Umu SU, Kahraman M, Laufer T, Haas J, Staehler C, Ludwig N, Hübenthal M, Meder B, Franke A, Lenhof HP, Meese E, Keller A.

Bioinformatics. 2018 May 15;34(10):1621-1628. doi: 10.1093/bioinformatics/btx814.


A review of databases predicting the effects of SNPs in miRNA genes or miRNA-binding sites.

Fehlmann T, Sahay S, Keller A, Backes C.

Brief Bioinform. 2017 Nov 27. doi: 10.1093/bib/bbx155. [Epub ahead of print]


Therapeutic implications of tumor free margins in head and neck squamous cell carcinoma.

Backes C, Bier H, Knopf A.

Oncotarget. 2017 Sep 16;8(48):84320-84328. doi: 10.18632/oncotarget.21035. eCollection 2017 Oct 13.


Micro-ribonucleic acids and extracellular vesicles repertoire in the spent culture media is altered in women undergoing In Vitro Fertilization.

Abu-Halima M, Häusler S, Backes C, Fehlmann T, Staib C, Nestel S, Nazarenko I, Meese E, Keller A.

Sci Rep. 2017 Oct 19;7(1):13525. doi: 10.1038/s41598-017-13683-8.


miRCarta: a central repository for collecting miRNA candidates.

Backes C, Fehlmann T, Kern F, Kehl T, Lenhof HP, Meese E, Keller A.

Nucleic Acids Res. 2018 Jan 4;46(D1):D160-D167. doi: 10.1093/nar/gkx851.


IMOTA: an interactive multi-omics tissue atlas for the analysis of human miRNA-target interactions.

Palmieri V, Backes C, Ludwig N, Fehlmann T, Kern F, Meese E, Keller A.

Nucleic Acids Res. 2018 Jan 4;46(D1):D770-D775. doi: 10.1093/nar/gkx701.


Web-based NGS data analysis using miRMaster: a large-scale meta-analysis of human miRNAs.

Fehlmann T, Backes C, Kahraman M, Haas J, Ludwig N, Posch AE, Würstle ML, Hübenthal M, Franke A, Meder B, Meese E, Keller A.

Nucleic Acids Res. 2017 Sep 6;45(15):8731-8744. doi: 10.1093/nar/gkx595.


NFATc1 controls the cytotoxicity of CD8+ T cells.

Klein-Hessling S, Muhammad K, Klein M, Pusch T, Rudolf R, Flöter J, Qureischi M, Beilhack A, Vaeth M, Kummerow C, Backes C, Schoppmeyer R, Hahn U, Hoth M, Bopp T, Berberich-Siebelt F, Patra A, Avots A, Müller N, Schulze A, Serfling E.

Nat Commun. 2017 Sep 11;8(1):511. doi: 10.1038/s41467-017-00612-6.


Determinants of Sunburn and Sun Protection of Agricultural Workers During Occupational and Recreational Activities.

Backes C, Milon A, Koechlin A, Vernez D, Bulliard JL.

J Occup Environ Med. 2017 Nov;59(11):1089-1094. doi: 10.1097/JOM.0000000000001140.


Transcatheter Occlusion of the Patent Ductus Arteriosus in 747 Infants <6 kg: Insights From the NCDR IMPACT Registry.

Backes CH, Kennedy KF, Locke M, Cua CL, Ball MK, Fick TA, Rivera BK, Smith CV, Holzer RJ, Boe BA, Berman DP, Bergersen L, Armstrong AK.

JACC Cardiovasc Interv. 2017 Sep 11;10(17):1729-1737. doi: 10.1016/j.jcin.2017.05.018. Epub 2017 Aug 16.


Sources to variability in circulating human miRNA signatures.

Keller A, Rounge T, Backes C, Ludwig N, Gislefoss R, Leidinger P, Langseth H, Meese E.

RNA Biol. 2017 Dec 2;14(12):1791-1798. doi: 10.1080/15476286.2017.1367888. Epub 2017 Sep 13.


Technical Stability and Biological Variability in MicroRNAs from Dried Blood Spots: A Lung Cancer Therapy-Monitoring Showcase.

Kahraman M, Laufer T, Backes C, Schrörs H, Fehlmann T, Ludwig N, Kohlhaas J, Meese E, Wehler T, Bals R, Keller A.

Clin Chem. 2017 Sep;63(9):1476-1488. doi: 10.1373/clinchem.2017.271619. Epub 2017 Jul 5.


TRPC1- and TRPC3-dependent Ca2+ signaling in mouse cortical astrocytes affects injury-evoked astrogliosis in vivo.

Belkacemi T, Niermann A, Hofmann L, Wissenbach U, Birnbaumer L, Leidinger P, Backes C, Meese E, Keller A, Bai X, Scheller A, Kirchhoff F, Philipp SE, Weissgerber P, Flockerzi V, Beck A.

Glia. 2017 Sep;65(9):1535-1549. doi: 10.1002/glia.23180. Epub 2017 Jun 21.


Necrotizing Enterocolitis Incidence, Characteristics, and Outcomes in Neonatal Down Syndrome Patients.

Cua CL, Haque U, Miao Y, Backes CH.

Am J Perinatol. 2017 Nov;34(13):1368-1374. doi: 10.1055/s-0037-1603688. Epub 2017 Jun 2. No abstract available.


BusyBee Web: metagenomic data analysis by bootstrapped supervised binning and annotation.

Laczny CC, Kiefer C, Galata V, Fehlmann T, Backes C, Keller A.

Nucleic Acids Res. 2017 Jul 3;45(W1):W171-W179. doi: 10.1093/nar/gkx348.


RegulatorTrail: a web service for the identification of key transcriptional regulators.

Kehl T, Schneider L, Schmidt F, Stöckel D, Gerstner N, Backes C, Meese E, Keller A, Schulz MH, Lenhof HP.

Nucleic Acids Res. 2017 Jul 3;45(W1):W146-W153. doi: 10.1093/nar/gkx350.


Differences in mortality characteristics in neonates with Down's syndrome.

Cua CL, Haque U, Santoro S, Nicholson L, Backes CH.

J Perinatol. 2017 Apr;37(4):465. doi: 10.1038/jp.2017.16. No abstract available.


Persistent Oxygen Requirement beyond Prematurity: A Case of Acquired Pulmonary Vein Stenosis.

Fick TA, Richards B, Backes CH, Ball MK.

Case Rep Pediatr. 2017;2017:3106871. doi: 10.1155/2017/3106871. Epub 2017 Mar 14.


All-printed thin-film transistors from networks of liquid-exfoliated nanosheets.

Kelly AG, Hallam T, Backes C, Harvey A, Esmaeily AS, Godwin I, Coelho J, Nicolosi V, Lauth J, Kulkarni A, Kinge S, Siebbeles LD, Duesberg GS, Coleman JN.

Science. 2017 Apr 7;356(6333):69-73. doi: 10.1126/science.aal4062.


The extracellular adherence protein (Eap) of Staphylococcus aureus acts as a proliferation and migration repressing factor that alters the cell morphology of keratinocytes.

Eisenbeis J, Peisker H, Backes CS, Bur S, Hölters S, Thewes N, Greiner M, Junker C, Schwarz EC, Hoth M, Junker K, Preissner KT, Jacobs K, Herrmann M, Bischoff M.

Int J Med Microbiol. 2017 Feb;307(2):116-125. doi: 10.1016/j.ijmm.2017.01.002. Epub 2017 Jan 18.


Percutaneous Patent Ductus Arteriosus (PDA) Closure During Infancy: A Meta-analysis.

Backes CH, Rivera BK, Bridge JA, Armstrong AK, Boe BA, Berman DP, Fick T, Holzer RJ, Hijazi ZM, Abadir S, Justino H, Bergersen L, Smith CV, Kirpalani H.

Pediatrics. 2017 Feb;139(2). pii: e20162927. doi: 10.1542/peds.2016-2927. Epub 2017 Jan 13. Review.


Differences in mortality characteristics in neonates with Down's syndrome.

Cua CL, Haque U, Santoro S, Nicholson L, Backes CH.

J Perinatol. 2017 Apr;37(4):427-431. doi: 10.1038/jp.2016.246. Epub 2017 Jan 12. Erratum in: J Perinatol. 2017 Apr;37(4):465.


Preparation of Liquid-exfoliated Transition Metal Dichalcogenide Nanosheets with Controlled Size and Thickness: A State of the Art Protocol.

Backes C, Hanlon D, Szydlowska BM, Harvey A, Smith RJ, Higgins TM, Coleman JN.

J Vis Exp. 2016 Dec 20;(118). doi: 10.3791/54806.


miRNAs in Ancient Tissue Specimens of the Tyrolean Iceman.

Keller A, Kreis S, Leidinger P, Maixner F, Ludwig N, Backes C, Galata V, Guerriero G, Fehlmann T, Franke A, Meder B, Zink A, Meese E.

Mol Biol Evol. 2017 Apr 1;34(4):793-801. doi: 10.1093/molbev/msw291.


Comparing genome versus proteome-based identification of clinical bacterial isolates.

Galata V, Backes C, Laczny CC, Hemmrich-Stanisak G, Li H, Smoot L, Posch AE, Schmolke S, Bischoff M, von Müller L, Plum A, Franke A, Keller A.

Brief Bioinform. 2018 May 1;19(3):495-505. doi: 10.1093/bib/bbw122.


Sensitive electromechanical sensors using viscoelastic graphene-polymer nanocomposites.

Boland CS, Khan U, Ryan G, Barwich S, Charifou R, Harvey A, Backes C, Li Z, Ferreira MS, Möbius ME, Young RJ, Coleman JN.

Science. 2016 Dec 9;354(6317):1257-1260. Epub 2016 Dec 8.


Extracorporeal Membrane Oxygenation Outcomes After the Comprehensive Stage II Procedure in Patients With Single Ventricles.

Gomez D, Duffy V, Hersey D, Backes C, Rycus P, McConnell P, Voss J, Galantowicz M, Cua CL.

Artif Organs. 2017 Jan;41(1):66-70. doi: 10.1111/aor.12810. Epub 2016 Nov 29.


cPAS-based sequencing on the BGISEQ-500 to explore small non-coding RNAs.

Fehlmann T, Reinheimer S, Geng C, Su X, Drmanac S, Alexeev A, Zhang C, Backes C, Ludwig N, Hart M, An D, Zhu Z, Xu C, Chen A, Ni M, Liu J, Li Y, Poulter M, Li Y, Stähler C, Drmanac R, Xu X, Meese E, Keller A.

Clin Epigenetics. 2016 Nov 21;8:123. eCollection 2016.

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