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The six-gene expression signature in whole sampled sputum provides clinically feasible inflammatory phenotyping of asthma.

Frøssing L, Kjærsgaard Klein D, Backer V, Baines KJ, Porsbjerg C.

ERJ Open Res. 2020 Mar 9;6(1). pii: 00280-2019. doi: 10.1183/23120541.00280-2019. eCollection 2020 Jan.


NORDSTAR - Paving the way for a new era in asthma research.

Geale K, Darabi H, Lindh M, Wahl HF, Ström O, Cao H, Alvares L, Dodge R, Loefroth E, Altraja A, Backer V, Backman H, Bjermer L, Bossios A, Aarli BB, Dahlén B, Hilberg O, Jansson C, Kankaanranta H, Karjalainen J, Kauppi P, Kilpeläinen M, Lehmann S, Lehtimäki L, Lundbäck B, Sandström T, Ulrik CS, Sverrild A, Viinanen A, von Bülow A, Yasinska V, Porsbjerg C.

Eur Respir J. 2020 Mar 12. pii: 1902476. doi: 10.1183/13993003.02476-2019. [Epub ahead of print] No abstract available.



Backer V.

J Allergy Clin Immunol. 2020 Feb 29. pii: S0091-6749(20)30127-5. doi: 10.1016/j.jaci.2020.01.037. [Epub ahead of print] No abstract available.


The impact of dysfunctional breathing on the level of asthma control in difficult asthma.

Sedeh FB, Von Bülow A, Backer V, Bodtger U, Petersen US, Vest S, James HH, Porsbjerg C.

Respir Med. 2020 Mar;163:105894. doi: 10.1016/j.rmed.2020.105894. Epub 2020 Feb 8.


Asthma control and COPD symptom burden in patients using fixed-dose combination inhalers (SPRINT study).

Roche N, Plaza V, Backer V, van der Palen J, Cerveri I, Gonzalez C, Safioti G, Scheepstra I, Patino O, Singh D.

NPJ Prim Care Respir Med. 2020 Jan 7;30(1):1. doi: 10.1038/s41533-019-0159-1.


Can training induce inflammatory control in asthma, or is it symptom control only?

Pitzner-Fabricius A, Toennesen LL, Backer V.

Curr Opin Pulm Med. 2020 Jan;26(1):56-61. doi: 10.1097/MCP.0000000000000648.


ERS/TSANZ Task Force Statement on the management of reproduction and pregnancy in women with airways diseases.

Middleton PG, Gade EJ, Aguilera C, MacKillop L, Button BM, Coleman C, Johnson B, Albrechtsen C, Edenborough F, Rigau D, Gibson PG, Backer V.

Eur Respir J. 2020 Feb 6;55(2). pii: 1901208. doi: 10.1183/13993003.01208-2019. Print 2020 Feb.


Efficacy of bronchial thermoplasty in patients with severe asthma.

Madsen H, Henriksen DP, Backer V, Siersted HC, Bjerring N, Ulrik CS.

J Asthma. 2019 Oct 18:1-7. doi: 10.1080/02770903.2019.1678636. [Epub ahead of print]


SQ house dust mite sublingual immunotherapy for the treatment of adults with house dust mite-induced allergic rhinitis.

Meteran H, Backer V.

Expert Rev Clin Immunol. 2019 Nov;15(11):1127-1133. doi: 10.1080/1744666X.2020.1676731. Epub 2019 Oct 22.


Primary ciliary dyskinesia patients have the same P. aeruginosa clone in sinuses and lungs.

Arndal E, Johansen HK, Haagensen JAJ, Bartell JA, Marvig RL, Alanin M, Aanæs K, Høiby N, Nielsen KG, Backer V, von Buchwald C.

Eur Respir J. 2020 Jan 16;55(1). pii: 1901472. doi: 10.1183/13993003.01472-2019. Print 2020 Jan. No abstract available.


The risk of asthma is increased among women with polycystic ovary syndrome: a twin study.

Zierau L, Meteran H, Backer V, Lindenberg S, Skytthe A, Thomsen SF.

ERJ Open Res. 2019 Sep 16;5(3). pii: 00018-2018. doi: 10.1183/23120541.00018-2018. eCollection 2019 Jul.


Mannitol and the mechanisms behind bronchoconstriction.

Backer V.

J Allergy Clin Immunol. 2019 Oct;144(4):931-932. doi: 10.1016/j.jaci.2019.06.048. Epub 2019 Aug 28. No abstract available.


Effect of beta2 -adrenergic agonist and resistance training on maximal oxygen uptake and muscle oxidative enzymes in men.

Lemminger AK, Jessen S, Habib S, Onslev J, Xu SFS, Backer V, Bangsbo J, Hostrup M.

Scand J Med Sci Sports. 2019 Dec;29(12):1881-1891. doi: 10.1111/sms.13544. Epub 2019 Sep 13.


DuoResp® Spiromax® adherence, satisfaction and ease of use: findings from a multi-country observational study in patients with asthma and COPD in Europe (SPRINT).

van der Palen J, Cerveri I, Roche N, Singh D, Plaza V, Gonzalez C, Patino O, Scheepstra I, Safioti G, Backer V.

J Asthma. 2019 Jul 11:1-9. doi: 10.1080/02770903.2019.1634097. [Epub ahead of print]


The long-term effect of an exercise and diet intervention in asthma patients: a 1-year follow-up on a randomised controlled trial.

Bentzon AK, Loehde LW, Backer V, Toennesen L.

ERJ Open Res. 2019 Jun 24;5(2). pii: 00032-2019. doi: 10.1183/23120541.00032-2019. eCollection 2019 Apr.


Benralizumab for the Prevention of COPD Exacerbations.

Criner GJ, Celli BR, Brightling CE, Agusti A, Papi A, Singh D, Sin DD, Vogelmeier CF, Sciurba FC, Bafadhel M, Backer V, Kato M, Ramírez-Venegas A, Wei YF, Bjermer L, Shih VH, Jison M, O'Quinn S, Makulova N, Newbold P, Goldman M, Martin UJ; GALATHEA Study Investigators; TERRANOVA Study Investigators.

N Engl J Med. 2019 Sep 12;381(11):1023-1034. doi: 10.1056/NEJMoa1905248. Epub 2019 May 20.


A systematic review of surgical treatment for supraglottic exercise-induced laryngeal obstruction.

Siewers K, Backer V, Walsted ES.

Laryngoscope Investig Otolaryngol. 2019 Mar 6;4(2):227-233. doi: 10.1002/lio2.257. eCollection 2019 Apr. Review.


Exposure to Vitamin D Fortification Policy in Prenatal Life and the Risk of Childhood Asthma: Results From the D-Tect Study.

Thorsteinsdottir F, Maslova E, Jacobsen R, Frederiksen P, Keller A, Backer V, Heitmann BL.

Nutrients. 2019 Apr 24;11(4). pii: E924. doi: 10.3390/nu11040924.


Listening to music prior to bronchoscopy reduces anxiety - a randomised controlled trial.

Jeppesen E, Pedersen CM, Larsen KR, Walsted ES, Rehl A, Ehrenreich J, Schnoor S, Backer V.

Eur Clin Respir J. 2019 Mar 17;6(1):1583517. doi: 10.1080/20018525.2019.1583517. eCollection 2019.


Association Between Chronic Obstructive Pulmonary Disease and Type 2 Diabetes: A Systematic Review and Meta-Analysis.

Rasmussen SM, Brok J, Backer V, Thomsen SF, Meteran H.

COPD. 2018 Oct;15(5):526-535. doi: 10.1080/15412555.2018.1532495.


High Prevalence of Laryngeal Obstruction during Exercise in Severe Asthma.

Hull JH, Walsted ES, Pavitt MJ, Menzies-Gow A, Backer V, Sandhu G.

Am J Respir Crit Care Med. 2019 Feb 15;199(4):538-542. doi: 10.1164/rccm.201809-1734LE. No abstract available.


Differentiation of adult severe asthma from difficult-to-treat asthma - Outcomes of a systematic assessment protocol.

von Bülow A, Backer V, Bodtger U, Søes-Petersen NU, Vest S, Steffensen I, Porsbjerg C.

Respir Med. 2018 Dec;145:41-47. doi: 10.1016/j.rmed.2018.10.020. Epub 2018 Oct 22.


Asthma severity and fertility outcome in women with polycystic ovary syndrome: a registry-based study.

Zierau L, Cortes R, Thomsen SF, Jimenez-Solem E, Lindenberg S, Backer V.

ERJ Open Res. 2018 Nov 5;4(4). pii: 00138-2017. doi: 10.1183/23120541.00138-2017. eCollection 2018 Oct.


Validation of ATS clinical practice guideline cut-points for FeNO in asthma.

Jeppegaard M, Veidal S, Sverrild A, Backer V, Porsbjerg C.

Respir Med. 2018 Nov;144:22-29. doi: 10.1016/j.rmed.2018.09.014. Epub 2018 Sep 22.


Self-reported intake of fruit and vegetables and risk of chronic obstructive pulmonary disease: A nation-wide twin study.

Meteran H, Thomsen SF, Miller MR, Hjelmborg J, Sigsgaard T, Backer V.

Respir Med. 2018 Nov;144:16-21. doi: 10.1016/j.rmed.2018.09.013. Epub 2018 Sep 20.


F eNO-based asthma management results in faster improvement of airway hyperresponsiveness.

Bernholm KF, Homøe AS, Meteran H, Jensen CB, Porsbjerg C, Backer V.

ERJ Open Res. 2018 Oct 3;4(4). pii: 00147-2017. doi: 10.1183/23120541.00147-2017. eCollection 2018 Oct.


Non-interventional study of the safety and effectiveness of fluticasone propionate/formoterol fumarate in real-world asthma management.

Backer V, Ellery A, Borzova S, Lane S, Kleiberova M, Bengtsson P, Tomala T, Basset-Stheme D, Bennett C, Lindner D, Meiners A, Overend T.

Ther Adv Respir Dis. 2018 Jan-Dec;12:1753466618796987. doi: 10.1177/1753466618796987.


Development of the International Severe Asthma Registry (ISAR): A Modified Delphi Study.

Bulathsinhala L, Eleangovan N, Heaney LG, Menzies-Gow A, Gibson PG, Peters M, Hew M, van Boven JFM, Lehtimäki L, van Ganse E, Belhassen M, Harvey ES, Perez de Llano L, Maitland-van der Zee AH, Papadopoulos NG, FitzGerald JM, Porsbjerg C, Canonica GW, Backer V, Rhee CK, Verhamme KMC, Buhl R, Cosio BG, Carter V, Price C, Le T, Stagno d'Alcontres M, Gopalan G, Tran TN, Price D.

J Allergy Clin Immunol Pract. 2019 Feb;7(2):578-588.e2. doi: 10.1016/j.jaip.2018.08.016. Epub 2018 Sep 1.


Quantification and Analysis of Laryngeal Closure From Endoscopic Videos.

Lin J, Walsted ES, Backer V, Hull JH, Elson DS.

IEEE Trans Biomed Eng. 2019 Apr;66(4):1127-1136. doi: 10.1109/TBME.2018.2867636. Epub 2018 Aug 29.


Beta2 -adrenoceptor agonist salbutamol increases protein turnover rates and alters signalling in skeletal muscle after resistance exercise in young men.

Hostrup M, Reitelseder S, Jessen S, Kalsen A, Nyberg M, Egelund J, Kreiberg M, Kristensen CM, Thomassen M, Pilegaard H, Backer V, Jacobson GA, Holm L, Bangsbo J.

J Physiol. 2018 Sep;596(17):4121-4139. doi: 10.1113/JP275560. Epub 2018 Jul 30.


Airway Interleukin-33 and type 2 cytokines in adult patients with acute asthma.

Poulsen NN, Bjerregaard A, Khoo SK, Laing IA, Le Souëf P, Backer V, Rapley L, Cohen SE, Barrett L, Thompson P, Baltic S, Porsbjerg C.

Respir Med. 2018 Jul;140:50-56. doi: 10.1016/j.rmed.2018.05.016. Epub 2018 May 19.


Effect of tralokinumab, an interleukin-13 neutralising monoclonal antibody, on eosinophilic airway inflammation in uncontrolled moderate-to-severe asthma (MESOS): a multicentre, double-blind, randomised, placebo-controlled phase 2 trial.

Russell RJ, Chachi L, FitzGerald JM, Backer V, Olivenstein R, Titlestad IL, Ulrik CS, Harrison T, Singh D, Chaudhuri R, Leaker B, McGarvey L, Siddiqui S, Wang M, Braddock M, Nordenmark LH, Cohen D, Parikh H, Colice G, Brightling CE; MESOS study investigators.

Lancet Respir Med. 2018 Jul;6(7):499-510. doi: 10.1016/S2213-2600(18)30201-7. Epub 2018 May 21.


Feasibility of high-intensity training in asthma.

Toennesen LL, Soerensen ED, Hostrup M, Porsbjerg C, Bangsbo J, Backer V.

Eur Clin Respir J. 2018 May 11;5(1):1468714. doi: 10.1080/20018525.2018.1468714. eCollection 2018.


Hypertrophic effect of inhaled beta2 -agonist with and without concurrent exercise training: A randomized controlled trial.

Jessen S, Onslev J, Lemminger A, Backer V, Bangsbo J, Hostrup M.

Scand J Med Sci Sports. 2018 Oct;28(10):2114-2122. doi: 10.1111/sms.13221. Epub 2018 Jun 7.


Pharmacologic Strategies for Exercise-Induced Bronchospasm with a Focus on Athletes.

Backer V, Mastronarde J.

Immunol Allergy Clin North Am. 2018 May;38(2):231-243. doi: 10.1016/j.iac.2018.01.011. Review.


Nordic consensus statement on the systematic assessment and management of possible severe asthma in adults.

Porsbjerg C, Ulrik C, Skjold T, Backer V, Laerum B, Lehman S, Janson C, Sandstrøm T, Bjermer L, Dahlen B, Lundbäck B, Ludviksdottir D, Björnsdóttir U, Altraja A, Lehtimäki L, Kauppi P, Karjalainen J, Kankaanranta H.

Eur Clin Respir J. 2018 Mar 6;5(1):1440868. doi: 10.1080/20018525.2018.1440868. eCollection 2018. Review.


Adherence and quality of life in adults and children during 3-years of SLIT treatment with Grazax-a real life study.

Kiotseridis H, Arvidsson P, Backer V, Braendholt V, Tunsäter A.

NPJ Prim Care Respir Med. 2018 Feb 12;28(1):4. doi: 10.1038/s41533-018-0072-z.


Allergic asthma is associated with increased risk of infections requiring antibiotics.

Woehlk C, von Bülow A, Kriegbaum M, Backer V, Porsbjerg C.

Ann Allergy Asthma Immunol. 2018 Feb;120(2):169-176.e1. doi: 10.1016/j.anai.2017.11.015.


The efficacy of a high protein/low glycemic index diet intervention in non-obese patients with asthma.

Geiker NRW, Toennesen LL, Astrup A, Backer V.

Eur J Clin Nutr. 2018 Apr;72(4):511-516. doi: 10.1038/s41430-018-0092-3. Epub 2018 Feb 6.


Lung function discordance in monozygotic twins and associated differences in blood DNA methylation.

Bolund ACS, Starnawska A, Miller MR, Schlünssen V, Backer V, Børglum AD, Christensen K, Tan Q, Christiansen L, Sigsgaard T.

Clin Epigenetics. 2017 Dec 21;9:132. doi: 10.1186/s13148-017-0427-2. eCollection 2017.


Objective confirmation of asthma diagnosis improves medication adherence.

Backer V, Stensen L, Sverrild A, Wedge E, Porsbjerg C.

J Asthma. 2018 Nov;55(11):1262-1268. doi: 10.1080/02770903.2017.1410830. Epub 2017 Dec 26.


Knockdown of myeloid cell hypoxia-inducible factor-1α ameliorates the acute pathology in DSS-induced colitis.

Bäcker V, Cheung FY, Siveke JT, Fandrey J, Winning S.

PLoS One. 2017 Dec 20;12(12):e0190074. doi: 10.1371/journal.pone.0190074. eCollection 2017.


The impact of different spirometric definitions on the prevalence of airway obstruction and their association with respiratory symptoms.

Meteran H, Miller MR, Thomsen SF, Christensen K, Sigsgaard T, Backer V.

ERJ Open Res. 2017 Dec 8;3(4). pii: 00110-2017. doi: 10.1183/23120541.00110-2017. eCollection 2017 Oct.


Ergospirometry with concurrent fibre optic laryngoscopy: a randomised crossover study.

Mirza KK, Walsted ES, Backer V.

Eur Clin Respir J. 2017 Nov 20;4(1):1399033. doi: 10.1080/20018525.2017.1399033. eCollection 2017.


Exhaled and nasal nitric oxide in chronic rhinosinusitis patients with nasal polyps in primary care.

Frendø M, Håkansson K, Schwer S, Ravn AT, Meteran H, Porsbjerg C, Backer V, von Buchwald C.

Rhinology. 2018 Mar 1;56(1):59-64. doi: 10.4193/Rhin17.111.


Effects of Exercise and Diet in Nonobese Asthma Patients-A Randomized Controlled Trial.

Toennesen LL, Meteran H, Hostrup M, Wium Geiker NR, Jensen CB, Porsbjerg C, Astrup A, Bangsbo J, Parker D, Backer V.

J Allergy Clin Immunol Pract. 2018 May - Jun;6(3):803-811. doi: 10.1016/j.jaip.2017.09.028. Epub 2017 Nov 10.


Increased respiratory neural drive and work of breathing in exercise-induced laryngeal obstruction.

Walsted ES, Faisal A, Jolley CJ, Swanton LL, Pavitt MJ, Luo YM, Backer V, Polkey MI, Hull JH.

J Appl Physiol (1985). 2018 Feb 1;124(2):356-363. doi: 10.1152/japplphysiol.00691.2017. Epub 2017 Nov 2.


Inhaled Steroids and Active Smoking Drive Chronic Obstructive Pulmonary Disease Symptoms and Biomarkers to a Greater Degree Than Airflow Limitation.

Silkoff PE, Singh D, FitzGerald JM, Eich A, Ludwig-Sengpiel A, Chupp GC, Backer V, Porsbjerg C, Girodet PO, Dransfield MT, Baribaud F, Susulic VS, Loza MJ.

Biomark Insights. 2017 Sep 7;12:1177271917730306. doi: 10.1177/1177271917730306. eCollection 2017.

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