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Items: 1 to 50 of 76

1.

PTD4-apoptin induces Bcl-2-insensitive apoptosis in human cervical carcinoma in vitro and in vivo.

Liu XW, Yuan P, Tian J, Li LJ, Wang Y, Huang SC, Liu L, Backendorf C, Noteborn MH, Sun J.

Anticancer Drugs. 2016 Nov;27(10):979-87. doi: 10.1097/CAD.0000000000000415.

PMID:
27548349
2.

Apoptin towards safe and efficient anticancer therapies.

Backendorf C, Noteborn MH.

Adv Exp Med Biol. 2014;818:39-59. doi: 10.1007/978-1-4471-6458-6_3. Review.

PMID:
25001531
3.

Reactive oxygen species (ROS) protection via cysteine oxidation in the epidermal cornified cell envelope.

Vermeij WP, Backendorf C.

Methods Mol Biol. 2014;1195:157-69. doi: 10.1007/7651_2013_51.

PMID:
24281873
4.

Human papillomavirus (HPV) upregulates the cellular deubiquitinase UCHL1 to suppress the keratinocyte's innate immune response.

Karim R, Tummers B, Meyers C, Biryukov JL, Alam S, Backendorf C, Jha V, Offringa R, van Ommen GJ, Melief CJ, Guardavaccaro D, Boer JM, van der Burg SH.

PLoS Pathog. 2013;9(5):e1003384. doi: 10.1371/journal.ppat.1003384. Epub 2013 May 23.

5.

Mitotic catastrophe triggered in human cancer cells by the viral protein apoptin.

Lanz HL, Zimmerman RM, Brouwer J, Noteborn MH, Backendorf C.

Cell Death Dis. 2013 Feb 7;4:e487. doi: 10.1038/cddis.2013.2.

6.

Folic acid-modified mesoporous silica nanoparticles for cellular and nuclear targeted drug delivery.

Porta F, Lamers GE, Morrhayim J, Chatzopoulou A, Schaaf M, den Dulk H, Backendorf C, Zink JI, Kros A.

Adv Healthc Mater. 2013 Feb;2(2):281-6. doi: 10.1002/adhm.201200176. Epub 2012 Aug 28. No abstract available.

PMID:
23184490
7.

Proteasomal insensitivity of apoptin in tumor cells.

Lanz HL, Suijker J, Noteborn MH, Backendorf C.

Biochem Biophys Res Commun. 2012 May 25;422(1):169-73. doi: 10.1016/j.bbrc.2012.04.132. Epub 2012 Apr 30.

PMID:
22575449
8.

Proteomic identification of in vivo interactors reveals novel function of skin cornification proteins.

Vermeij WP, Florea BI, Isenia S, Alia A, Brouwer J, Backendorf C.

J Proteome Res. 2012 Jun 1;11(6):3068-76. doi: 10.1021/pr300310b. Epub 2012 May 11.

PMID:
22519520
9.

PP2A inactivation is a crucial step in triggering apoptin-induced tumor-selective cell killing.

Zimmerman R, Peng DJ, Lanz H, Zhang YH, Danen-Van Oorschot A, Qu S, Backendorf C, Noteborn M.

Cell Death Dis. 2012 Apr 5;3:e291. doi: 10.1038/cddis.2012.31.

10.

Development and application of an in vitro apoptin kinase assay.

Lanz HL, Florea BI, Noteborn MH, Backendorf C.

Anal Biochem. 2012 Feb 1;421(1):68-74. doi: 10.1016/j.ab.2011.10.030. Epub 2011 Oct 22.

PMID:
22080040
11.

Human papillomavirus deregulates the response of a cellular network comprising of chemotactic and proinflammatory genes.

Karim R, Meyers C, Backendorf C, Ludigs K, Offringa R, van Ommen GJ, Melief CJ, van der Burg SH, Boer JM.

PLoS One. 2011 Mar 14;6(3):e17848. doi: 10.1371/journal.pone.0017848.

12.

ROS quenching potential of the epidermal cornified cell envelope.

Vermeij WP, Alia A, Backendorf C.

J Invest Dermatol. 2011 Jul;131(7):1435-41. doi: 10.1038/jid.2010.433. Epub 2011 Jan 20.

13.

Skin cornification proteins provide global link between ROS detoxification and cell migration during wound healing.

Vermeij WP, Backendorf C.

PLoS One. 2010 Aug 3;5(8):e11957. doi: 10.1371/journal.pone.0011957.

14.

Accurate non-invasive image-based cytotoxicity assays for cultured cells.

Marqués-Gallego P, den Dulk H, Backendorf C, Brouwer J, Reedijk J, Burke JF.

BMC Biotechnol. 2010 Jun 17;10:43. doi: 10.1186/1472-6750-10-43.

15.

Matched cultures of keratinocytes and fibroblasts derived from normal and NER-deficient mouse models.

Pines A, Backendorf C.

Methods Mol Biol. 2010;585:45-57. doi: 10.1007/978-1-60761-380-0_4.

PMID:
19907995
16.

Family at last: highlights of the first international meeting on proteins killing tumour cells.

Bruno P, Brinkmann CR, Boulanger MC, Flinterman M, Klanrit P, Landry MC, Portsmouth D, Borst J, Tavassoli M, Noteborn M, Backendorf C, Zimmerman RM.

Cell Death Differ. 2009 Jan;16(1):184-6. doi: 10.1038/cdd.2008.164. No abstract available.

17.

Differential activity of UV-DDB in mouse keratinocytes and fibroblasts: impact on DNA repair and UV-induced skin cancer.

Pines A, Backendorf C, Alekseev S, Jansen JG, de Gruijl FR, Vrieling H, Mullenders LH.

DNA Repair (Amst). 2009 Feb 1;8(2):153-61. doi: 10.1016/j.dnarep.2008.09.011. Epub 2008 Dec 4.

PMID:
18996499
18.

TwinGFP, a marker for cell cycle analysis in transiently transfected cells.

Niemantsverdriet M, Backendorf C.

Anal Biochem. 2008 Apr 15;375(2):173-8. doi: 10.1016/j.ab.2008.01.015. Epub 2008 Jan 18.

PMID:
18261454
19.

Apoptin: therapeutic potential of an early sensor of carcinogenic transformation.

Backendorf C, Visser AE, de Boer AG, Zimmerman R, Visser M, Voskamp P, Zhang YH, Noteborn M.

Annu Rev Pharmacol Toxicol. 2008;48:143-69. Review.

PMID:
17848136
20.

Cellular functions of 14-3-3 zeta in apoptosis and cell adhesion emphasize its oncogenic character.

Niemantsverdriet M, Wagner K, Visser M, Backendorf C.

Oncogene. 2008 Feb 21;27(9):1315-9. Epub 2007 Aug 20.

PMID:
17704798
21.

Identification of regulatory elements by gene family footprinting and in vivo analysis.

Fischer DF, Backendorf C.

Adv Biochem Eng Biotechnol. 2007;104:37-64. Review.

PMID:
17290818
22.

Additive cytotoxic effect of apoptin and chemotherapeutic agents paclitaxel and etoposide on human tumour cells.

Olijslagers SJ, Zhang YH, Backendorf C, Noteborn MH.

Basic Clin Pharmacol Toxicol. 2007 Feb;100(2):127-31.

23.

Plasmid DNA encapsulation within cationic diblock copolymer vesicles for gene delivery.

Korobko AV, Backendorf C, van der Maarel JR.

J Phys Chem B. 2006 Aug 3;110(30):14550-6.

PMID:
16869554
24.

Epidermal transit of replication-arrested, undifferentiated keratinocytes in UV-exposed XPC mice: an alternative to in situ apoptosis.

Stout GJ, Westdijk D, Calkhoven DM, Pijper O, Backendorf CM, Willemze R, Mullenders LH, de Gruijl FR.

Proc Natl Acad Sci U S A. 2005 Dec 27;102(52):18980-5. Epub 2005 Dec 19.

25.

Enhanced DDB2 expression protects mice from carcinogenic effects of chronic UV-B irradiation.

Alekseev S, Kool H, Rebel H, Fousteri M, Moser J, Backendorf C, de Gruijl FR, Vrieling H, Mullenders LH.

Cancer Res. 2005 Nov 15;65(22):10298-306.

26.

Repair characteristics and differentiation propensity of long-term cultures of epidermal keratinocytes derived from normal and NER-deficient mice.

Backendorf C, de Wit J, van Oosten M, Stout GJ, Mitchell JR, Borgstein AM, van der Horst GT, de Gruijl FR, Brouwer J, Mullenders LH, Hoeijmakers JH.

DNA Repair (Amst). 2005 Nov 21;4(11):1325-36. Epub 2005 Sep 22.

PMID:
16182615
27.

Selective DNA damage responses in murine Xpa-/-, Xpc-/- and Csb-/- keratinocyte cultures.

Stout GJ, Oosten Mv, Acherrat FZ, Wit Jd, Vermeij WP, Mullenders LH, Gruijl FR, Backendorf C.

DNA Repair (Amst). 2005 Nov 21;4(11):1337-44. Epub 2005 Sep 22.

PMID:
16182614
28.

Radiation response and cell cycle regulation of p53 rescued malignant keratinocytes.

Niemantsverdriet M, Jongmans W, Backendorf C.

Exp Cell Res. 2005 Oct 15;310(1):237-47.

PMID:
16120440
29.

RT-PCR analysis of p73 splice variants, ease or tease?

Niemantsverdriet M, Vermeij WP, Backendorf C.

Leukemia. 2005 Sep;19(9):1685-6. No abstract available.

PMID:
16034465
30.

Mismatch repair protein Msh2 contributes to UVB-induced cell cycle arrest in epidermal and cultured mouse keratinocytes.

van Oosten M, Stout GJ, Backendorf C, Rebel H, de Wind N, Darroudi F, van Kranen HJ, de Gruijl FR, Mullenders LH.

DNA Repair (Amst). 2005 Jan 2;4(1):81-9.

PMID:
15533840
31.

Promoter analysis in the human SPRR gene family.

Fischer DF, Backendorf C.

Methods Mol Biol. 2005;289:303-14.

PMID:
15502194
32.

Isoform-specific differences in rapid nucleocytoplasmic shuttling cause distinct subcellular distributions of 14-3-3 sigma and 14-3-3 zeta.

van Hemert MJ, Niemantsverdriet M, Schmidt T, Backendorf C, Spaink HP.

J Cell Sci. 2004 Mar 15;117(Pt 8):1411-20. Epub 2004 Mar 2.

33.

Distinct functional interactions of human Skn-1 isoforms with Ese-1 during keratinocyte terminal differentiation.

Cabral A, Fischer DF, Vermeij WP, Backendorf C.

J Biol Chem. 2003 May 16;278(20):17792-9. Epub 2003 Mar 6.

34.

Liquid crystal formation in supercoiled DNA solutions.

Zakharova SS, Jesse W, Backendorf C, van der Maarel JR.

Biophys J. 2002 Aug;83(2):1119-29.

35.

Dimensions of plectonemically supercoiled DNA.

Zakharova SS, Jesse W, Backendorf C, Egelhaaf SU, Lapp A, van der Maarel JR.

Biophys J. 2002 Aug;83(2):1106-18.

36.

SPRR4, a novel cornified envelope precursor: UV-dependent epidermal expression and selective incorporation into fragile envelopes.

Cabral A, Sayin A, de Winter S, Fischer DF, Pavel S, Backendorf C.

J Cell Sci. 2001 Nov;114(Pt 21):3837-43.

37.

Structural organization and regulation of the small proline-rich family of cornified envelope precursors suggest a role in adaptive barrier function.

Cabral A, Voskamp P, Cleton-Jansen AM, South A, Nizetic D, Backendorf C.

J Biol Chem. 2001 Jun 1;276(22):19231-7. Epub 2001 Mar 15.

38.
39.

Opposite effects of Ras or PKC activation on the expression of the SPRR2A keratinocyte terminal differentiation marker.

Sark MW, Borgstein AM, Medema JP, van de Putte P, Backendorf C.

Exp Cell Res. 1999 Aug 1;250(2):475-84.

PMID:
10413601
40.

Human epidermal differentiation complex in a single 2.5 Mbp long continuum of overlapping DNA cloned in bacteria integrating physical and transcript maps.

South AP, Cabral A, Ives JH, James CH, Mirza G, Marenholz I, Mischke D, Backendorf C, Ragoussis J, Nizetic D.

J Invest Dermatol. 1999 Jun;112(6):910-8.

41.

Structure and evolution of the human SPRR3 gene: implications for function and regulation.

Fischer DF, Sark MW, Lehtola MM, Gibbs S, van de Putte P, Backendorf C.

Genomics. 1999 Jan 1;55(1):88-99.

PMID:
9889002
42.

Involvement of a nuclear matrix association region in the regulation of the SPRR2A keratinocyte terminal differentiation marker.

Fischer DF, van Drunen CM, Winkler GS, van de Putte P, Backendorf C.

Nucleic Acids Res. 1998 Dec 1;26(23):5288-94.

43.

AP-1 and ets transcription factors regulate the expression of the human SPRR1A keratinocyte terminal differentiation marker.

Sark MW, Fischer DF, de Meijer E, van de Putte P, Backendorf C.

J Biol Chem. 1998 Sep 18;273(38):24683-92.

44.

Apoptin induces apoptosis in human transformed and malignant cells but not in normal cells.

Danen-Van Oorschot AA, Fischer DF, Grimbergen JM, Klein B, Zhuang S, Falkenburg JH, Backendorf C, Quax PH, Van der Eb AJ, Noteborn MH.

Proc Natl Acad Sci U S A. 1997 May 27;94(11):5843-7.

45.

Involvement of c-JUN in the regulation of terminal differentiation genes in normal and malignant keratinocytes.

Lohman FP, Gibbs S, Fischer DF, Borgstein AM, van de Putte P, Backendorf C.

Oncogene. 1997 Apr 3;14(13):1623-7.

46.

Expression of the SPRR cornification genes is differentially affected by carcinogenic transformation.

Lohman FP, Medema JK, Gibbs S, Ponec M, van de Putte P, Backendorf C.

Exp Cell Res. 1997 Feb 25;231(1):141-8.

PMID:
9056421
47.
48.
49.

The small proline-rich proteins constitute a multigene family of differentially regulated cornified cell envelope precursor proteins.

Hohl D, de Viragh PA, Amiguet-Barras F, Gibbs S, Backendorf C, Huber M.

J Invest Dermatol. 1995 Jun;104(6):902-9.

50.

Calcium inhibits epidermal growth factor-induced activation of p21ras in human primary keratinocytes.

Medema JP, Sark MW, Backendorf C, Bos JL.

Mol Cell Biol. 1994 Nov;14(11):7078-85.

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