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Association of caspase 8 polymorphisms -652 6N InsDel and Asp302His with progression-free survival and tumor infiltrating lymphocytes in early breast cancer.

Kuhlmann JD, Bachmann HS, Link T, Wimberger P, Kröber E, Thomssen C, Mallé B, Bethmann D, Vetter M, Kantelhardt EJ.

Sci Rep. 2019 Aug 29;9(1):12594. doi: 10.1038/s41598-019-47601-x.


Transcriptional response of Lactococcus lactis during bacterial emulsification.

Tarazanova M, Huppertz T, Starrenburg M, Todt T, van Hijum S, Kok J, Bachmann H.

PLoS One. 2019 Jul 25;14(7):e0220048. doi: 10.1371/journal.pone.0220048. eCollection 2019.


SNPs Within the MTOR Gene Are Associated With an Increased Risk of Developing De Novo Diabetes Mellitus Following the Administration of Everolimus in Liver Transplant Recipients.

Husen P, Straub K, Willuweit K, Hagemann A, Wedemeyer H, Bachmann HS, Herzer K.

Transplant Proc. 2019 Jul - Aug;51(6):1962-1971. doi: 10.1016/j.transproceed.2019.03.027. Epub 2019 Jul 11.


Ampicillin-treated Lactococcus lactis MG1363 populations contain persisters as well as viable but non-culturable cells.

van Tatenhove-Pel RJ, Zwering E, Solopova A, Kuipers OP, Bachmann H.

Sci Rep. 2019 Jul 8;9(1):9867. doi: 10.1038/s41598-019-46344-z.


Genetic contribution to PONV risk.

Klenke S, de Vries GJ, Schiefer L, Seyffert N, Bachmann HS, Peters J, Frey UH.

Anaesth Crit Care Pain Med. 2019 May 8. pii: S2352-5568(18)30570-8. doi: 10.1016/j.accpm.2019.04.012. [Epub ahead of print]


Side Effects of Frequently Used Antihypertensive Drugs on Wound Healing in vitro.

Stuermer EK, Besser M, Terberger N, Bachmann HS, Severing AL.

Skin Pharmacol Physiol. 2019;32(3):162-172. doi: 10.1159/000499433. Epub 2019 Apr 24.


Editorial overview: Microbial solutions in food biotechnology: fermentation, cell factories and beneficial microbes.

Bachmann H, Neves AR.

Curr Opin Biotechnol. 2019 Apr;56:vi-viii. doi: 10.1016/j.copbio.2019.04.002. No abstract available.


The small molecule Bcl-2/Mcl-1 inhibitor TW-37 shows single-agent cytotoxicity in neuroblastoma cell lines.

Klenke S, Akdeli N, Stelmach P, Heukamp L, Schulte JH, Bachmann HS.

BMC Cancer. 2019 Mar 18;19(1):243. doi: 10.1186/s12885-019-5439-1.


Comparative Genome Analysis of Lactococcus lactis Indicates Niche Adaptation and Resolves Genotype/Phenotype Disparity.

Wels M, Siezen R, van Hijum S, Kelly WJ, Bachmann H.

Front Microbiol. 2019 Jan 31;10:4. doi: 10.3389/fmicb.2019.00004. eCollection 2019.


Adaption to glucose limitation is modulated by the pleotropic regulator CcpA, independent of selection pressure strength.

Price CE, Branco Dos Santos F, Hesseling A, Uusitalo JJ, Bachmann H, Benavente V, Goel A, Berkhout J, Bruggeman FJ, Marrink SJ, Montalban-Lopez M, de Jong A, Kok J, Molenaar D, Poolman B, Teusink B, Kuipers OP.

BMC Evol Biol. 2019 Jan 10;19(1):15. doi: 10.1186/s12862-018-1331-x.


Side effects of frequently used oral antidiabetics on wound healing in vitro.

Stuermer EK, Besser M, Terberger N, Koester V, Bachmann HS, Severing AL.

Naunyn Schmiedebergs Arch Pharmacol. 2019 Mar;392(3):371-380. doi: 10.1007/s00210-018-01597-9. Epub 2018 Dec 7.


Further Elucidation of Galactose Utilization in Lactococcus lactis MG1363.

Solopova A, Bachmann H, Teusink B, Kok J, Kuipers OP.

Front Microbiol. 2018 Aug 3;9:1803. doi: 10.3389/fmicb.2018.01803. eCollection 2018.


No Association of CALCA Polymorphisms and Aseptic Loosening after Primary Total Hip Arthroplasty.

Aydin-Yüce T, Kurscheid G, Bachmann HS, Gehrke T, Dudda M, Jäger M, Wedemeyer C, Kauther MD.

Biomed Res Int. 2018 Jun 5;2018:3687415. doi: 10.1155/2018/3687415. eCollection 2018.


CHRM3 rs2165870 polymorphism is independently associated with postoperative nausea and vomiting, but combined prophylaxis is effective.

Klenke S, de Vries GJ, Schiefer L, Seyffert N, Bachmann HS, Peters J, Frey UH.

Br J Anaesth. 2018 Jul;121(1):58-65. doi: 10.1016/j.bja.2018.02.025. Epub 2018 Apr 4.


Altering textural properties of fermented milk by using surface-engineered Lactococcus lactis.

Tarazanova M, Huppertz T, Kok J, Bachmann H.

Microb Biotechnol. 2018 Jul;11(4):770-780. doi: 10.1111/1751-7915.13278. Epub 2018 May 9.


1α,25(OH)2D3-glycosides from Solanum glaucophyllum leaves extract induce myoblasts differentiation through p38 MAPK and AKT activation.

Irazoqui AP, De Genaro P, Buitrago C, Bachmann H, González-Pardo V, Russo de Boland A.

Biol Open. 2018 May 14;7(5). pii: bio033670. doi: 10.1242/bio.033670.


Allosteric Activation of GDP-Bound Ras Isoforms by Bisphenol Derivative Plasticisers.

Schöpel M, Shkura O, Seidel J, Kock K, Zhong X, Löffek S, Helfrich I, Bachmann HS, Scherkenbeck J, Herrmann C, Stoll R.

Int J Mol Sci. 2018 Apr 10;19(4). pii: E1133. doi: 10.3390/ijms19041133.


Adjuvant treatment of resectable biliary tract cancer with cisplatin plus gemcitabine: A prospective single center phase II study.

Siebenhüner AR, Seifert H, Bachmann H, Seifert B, Winder T, Feilchenfeldt J, Breitenstein S, Clavien PA, Stupp R, Knuth A, Pestalozzi B, Samaras P.

BMC Cancer. 2018 Jan 11;18(1):72. doi: 10.1186/s12885-017-3967-0.


Mobilization of Hematopoietic Progenitor Cells with Standard- or Reduced-Dose Filgrastim after Vinorelbine in Multiple Myeloma Patients: A Randomized Prospective Single-Center Phase II Study.

Samaras P, Rütti MF, Seifert B, Bachmann H, Schanz U, Eisenring M, Renner C, Susanne Müller AM, Schmidt A, Mischo A, Fuchs I, Bargetzi M, Manz MG, Stupp R, Petrausch U, Stenner-Liewen F.

Biol Blood Marrow Transplant. 2018 Apr;24(4):694-699. doi: 10.1016/j.bbmt.2017.12.775. Epub 2017 Dec 12.


Phase I study of a chloroquine-gemcitabine combination in patients with metastatic or unresectable pancreatic cancer.

Samaras P, Tusup M, Nguyen-Kim TDL, Seifert B, Bachmann H, von Moos R, Knuth A, Pascolo S.

Cancer Chemother Pharmacol. 2017 Nov;80(5):1005-1012. doi: 10.1007/s00280-017-3446-y. Epub 2017 Oct 4.


Exploring the putative self-binding property of the human farnesyltransferase alpha-subunit.

Hagemann A, Müller G, Manthey I, Bachmann HS.

FEBS Lett. 2017 Nov;591(21):3637-3648. doi: 10.1002/1873-3468.12862. Epub 2017 Oct 11.


A single intraperitoneal injection of bovine fetuin-A attenuates bone resorption in a murine calvarial model of particle-induced osteolysis.

Jablonski H, Polan C, Wedemeyer C, Hilken G, Schlepper R, Bachmann HS, Grabellus F, Dudda M, Jäger M, Kauther MD.

Bone. 2017 Dec;105:262-268. doi: 10.1016/j.bone.2017.09.006. Epub 2017 Sep 21.


Cell Surface Properties of Lactococcus lactis Reveal Milk Protein Binding Specifically Evolved in Dairy Isolates.

Tarazanova M, Huppertz T, Beerthuyzen M, van Schalkwijk S, Janssen P, Wels M, Kok J, Bachmann H.

Front Microbiol. 2017 Sep 7;8:1691. doi: 10.3389/fmicb.2017.01691. eCollection 2017.


Neuroradiologic Characteristics of Primary Angiitis of the Central Nervous System According to the Affected Vessel Size.

Thaler C, Kaufmann-Bühler AK, Gansukh T, Gansukh A, Schuster S, Bachmann H, Thomalla G, Magnus T, Matschke J, Fiehler J, Siemonsen S.

Clin Neuroradiol. 2019 Mar;29(1):37-44. doi: 10.1007/s00062-017-0622-8. Epub 2017 Sep 5.


Relationship between GNAS1 T393C polymorphism and aseptic loosening after total hip arthroplasty.

Stelmach P, Kauther MD, Fuest L, Kurscheid G, Gehrke T, Klenke S, Jäger M, Wedemeyer C, Bachmann HS.

Eur J Med Res. 2017 Aug 23;22(1):29. doi: 10.1186/s40001-017-0271-z.


Corrigendum to "A portable low-cost long-term live-cell imaging platform for biomedical research and education" [Biosens. Bioelectron. 64 (2015) 639-649].

Walzik MP, Vollmar V, Lachnit T, Dietz H, Haug S, Bachmann H, Fath M, Aschenbrenner D, Mofrad SA, Friedrich O, Gilbert DF.

Biosens Bioelectron. 2018 Jan 15;99:683. doi: 10.1016/j.bios.2017.08.021. Epub 2017 Aug 12. No abstract available.


Subtypes of primary angiitis of the CNS identified by MRI patterns reflect the size of affected vessels.

Schuster S, Bachmann H, Thom V, Kaufmann-Buehler AK, Matschke J, Siemonsen S, Glatzel M, Fiehler J, Gerloff C, Magnus T, Thomalla G.

J Neurol Neurosurg Psychiatry. 2017 Sep;88(9):749-755. doi: 10.1136/jnnp-2017-315691. Epub 2017 Jul 13.


Experimental evolution and the adjustment of metabolic strategies in lactic acid bacteria.

Bachmann H, Molenaar D, Branco Dos Santos F, Teusink B.

FEMS Microbiol Rev. 2017 Aug 1;41(Supp_1):S201-S219. doi: 10.1093/femsre/fux024. Review.


Hypoxia Inducible Factor-2 Alpha and Prolinhydroxylase 2 Polymorphisms in Patients with Acute Respiratory Distress Syndrome (ARDS).

Dötsch A, Eisele L, Rabeling M, Rump K, Walstein K, Bick A, Cox L, Engler A, Bachmann HS, Jöckel KH, Adamzik M, Peters J, Schäfer ST.

Int J Mol Sci. 2017 Jun 14;18(6). pii: E1266. doi: 10.3390/ijms18061266.


[Diagnosis, therapy and prophylactic measures of parturient paresis in dairy cattle: results of an online survey for Swiss veterinarians].

Perruchoud T, Maeschli A, Bachmann H, Walkenhorst M, Schüpbach G, Mevissen M, Zanolari P.

Schweiz Arch Tierheilkd. 2017 Jun;159(6):335-343. doi: 10.17236/sat00119. German.


Impact of BCL2 polymorphisms on survival in transitional cell carcinoma of the bladder.

Hess J, Stelmach P, Eisenhardt A, Rübben H, Reis H, Schmid KW, Bachmann HS.

J Cancer Res Clin Oncol. 2017 Sep;143(9):1659-1670. doi: 10.1007/s00432-017-2404-8. Epub 2017 Apr 17.


Draft Genome Sequences of 24 Lactococcus lactis Strains.

Backus L, Wels M, Boekhorst J, Dijkstra AR, Beerthuyzen M, Kelly WJ, Siezen RJ, van Hijum SA, Bachmann H.

Genome Announc. 2017 Mar 30;5(13). pii: e01737-16. doi: 10.1128/genomeA.01737-16.


Effects of a sustained release formulation of 1,25-dihydroxyvitamin D3-glycosides for milk fever prevention on serum 1,25-dihydroxyvitamin D3, calcium and phosphorus in dairy cows.

Bachmann H, Lanz M, Kehrle S, Bittner W, Toggenburger A, Mathis GA, Rambeck W.

J Steroid Biochem Mol Biol. 2017 Oct;173:301-307. doi: 10.1016/j.jsbmb.2017.03.020. Epub 2017 Mar 23.


Draft Genome Sequences of 11 Lactococcus lactis subsp. cremoris Strains.

Wels M, Backus L, Boekhorst J, Dijkstra A, Beerthuyzen M, Siezen RJ, Bachmann H, van Hijum SA.

Genome Announc. 2017 Mar 16;5(11). pii: e01739-16. doi: 10.1128/genomeA.01739-16.


Plasmid Complement of Lactococcus lactis NCDO712 Reveals a Novel Pilus Gene Cluster.

Tarazanova M, Beerthuyzen M, Siezen R, Fernandez-Gutierrez MM, de Jong A, van der Meulen S, Kok J, Bachmann H.

PLoS One. 2016 Dec 12;11(12):e0167970. doi: 10.1371/journal.pone.0167970. eCollection 2016.


Nonhierarchical Flux Regulation Exposes the Fitness Burden Associated with Lactate Production in Synechocystis sp. PCC6803.

Du W, Angermayr SA, Jongbloets JA, Molenaar D, Bachmann H, Hellingwerf KJ, Branco Dos Santos F.

ACS Synth Biol. 2017 Mar 17;6(3):395-401. doi: 10.1021/acssynbio.6b00235. Epub 2016 Dec 12.


Safety profile of 1,25-dihydroxyvitamin D3 of herbal origin in broiler chicken.

Mathis G, Boland R, Bachmann H, Toggenburger A, Rambeck W.

Schweiz Arch Tierheilkd. 2016 Dec;158(12):819-826.


Hypoxia inducible factor-1 alpha and prolinhydroxlase 2 polymorphisms in patients with severe sepsis: a prospective observational trial.

Höcker A, Rabeling M, Bick A, Cox L, Kreuzer M, Engler A, Walstein K, Bachmann HS, Jöckel KH, Eisele L, Adamzik M, Peters J, Schäfer ST.

BMC Anesthesiol. 2016 Aug 11;16(1):61. doi: 10.1186/s12871-016-0225-y.


Prognostic relevance of caspase 8 -652 6N InsDel and Asp302His polymorphisms for breast cancer.

Kuhlmann JD, Bankfalvi A, Schmid KW, Callies R, Kimmig R, Wimberger P, Siffert W, Bachmann HS.

BMC Cancer. 2016 Aug 9;16:618. doi: 10.1186/s12885-016-2662-x.


Association of a Common Oxytocin Receptor Gene Polymorphism with Self-Reported 'Empathic Concern' in a Large Population of Healthy Volunteers.

Huetter FK, Bachmann HS, Reinders A, Siffert D, Stelmach P, Knop D, Horn PA, Siffert W.

PLoS One. 2016 Jul 28;11(7):e0160059. doi: 10.1371/journal.pone.0160059. eCollection 2016.


A Single Dose of the Anti-Resorptive Peptide Human Calcitonin Paradoxically Augments Particle- and Endotoxin-Mediated Pro-Inflammatory Cytokine Production In Vitro.

Jablonski H, Wedemeyer C, Bachmann HS, Schlagkamp M, Bernstein A, Jäger M, Kauther MD.

Horm Metab Res. 2016 Sep;48(9):607-12. doi: 10.1055/s-0042-108338. Epub 2016 Jun 3.


Public goods and metabolic strategies.

Bachmann H, Bruggeman FJ, Molenaar D, Branco Dos Santos F, Teusink B.

Curr Opin Microbiol. 2016 Jun;31:109-115. doi: 10.1016/j.mib.2016.03.007. Epub 2016 Apr 4. Review.


In vitro effects of 1α,25(OH)₂D₃-glycosides from Solbone A (Solanum glaucophyllum leaves extract; Herbonis AG) compared to synthetic 1α,25(OH)₂D₃ on myogenesis.

Gili V, Pardo VG, Ronda AC, De Genaro P, Bachmann H, Boland R, de Boland AR.

Steroids. 2016 May;109:7-15. doi: 10.1016/j.steroids.2016.03.002. Epub 2016 Mar 8.


The BCL2 -938C>A Promoter Polymorphism Is Associated with Risk for and Time to Aseptic Loosening of Total Hip Arthroplasty.

Stelmach P, Wedemeyer C, Fuest L, Kurscheid G, Gehrke T, Klenke S, Jäger M, Kauther MD, Bachmann HS.

PLoS One. 2016 Feb 16;11(2):e0149528. doi: 10.1371/journal.pone.0149528. eCollection 2016.


Toward the Standardization of Biochar Analysis: The COST Action TD1107 Interlaboratory Comparison.

Bachmann HJ, Bucheli TD, Dieguez-Alonso A, Fabbri D, Knicker H, Schmidt HP, Ulbricht A, Becker R, Buscaroli A, Buerge D, Cross A, Dickinson D, Enders A, Esteves VI, Evangelou MW, Fellet G, Friedrich K, Gasco Guerrero G, Glaser B, Hanke UM, Hanley K, Hilber I, Kalderis D, Leifeld J, Masek O, Mumme J, Carmona MP, Calvelo Pereira R, Rees F, Rombolà AG, de la Rosa JM, Sakrabani R, Sohi S, Soja G, Valagussa M, Verheijen F, Zehetner F.

J Agric Food Chem. 2016 Jan 20;64(2):513-27. doi: 10.1021/acs.jafc.5b05055. Epub 2016 Jan 6.


Metastatic status of sentinel lymph nodes in melanoma determined noninvasively with multispectral optoacoustic imaging.

Stoffels I, Morscher S, Helfrich I, Hillen U, Leyh J, Burton NC, Sardella TC, Claussen J, Poeppel TD, Bachmann HS, Roesch A, Griewank K, Schadendorf D, Gunzer M, Klode J.

Sci Transl Med. 2015 Dec 9;7(317):317ra199. doi: 10.1126/scitranslmed.aad1278. Erratum in: Sci Transl Med. 2015 Dec 23;7(319):319er8. Lehy, Julia [corrected to Leyh, Julia].


Absence of telomerase reverse transcriptase promoter mutations in neuroblastoma.

Lindner S, Bachmann HS, Odersky A, Schaefers S, Klein-Hitpass L, Hero B, Fischer M, Eggert A, Schramm A, Schulte JH.

Biomed Rep. 2015 Jul;3(4):443-446. Epub 2015 May 13.


AQP1, AQP5, Bcl-2 and p16 in pharyngeal squamous cell carcinoma.

Lehnerdt GF, Bachmann HS, Adamzik M, Panic A, Köksal E, Weller P, Lang S, Schmid KW, Siffert W, Bankfalvi A.

J Laryngol Otol. 2015 Jun;129(6):580-6. doi: 10.1017/S002221511500119X.


Metabolism at evolutionary optimal States.

Rabbers I, van Heerden JH, Nordholt N, Bachmann H, Teusink B, Bruggeman FJ.

Metabolites. 2015 Jun 2;5(2):311-43. doi: 10.3390/metabo5020311. Review.


The FNTB promoter polymorphism rs11623866 as a potential predictive biomarker for lonafarnib treatment of ovarian cancer patients.

Bachmann HS, Meier W, du Bois A, Kimmig R, Kuhlmann JD, Siffert W, Sehouli J, Wollschlaeger K, Huober J, Hillemanns P, Burges A, Schmalfeldt B, Aminossadati B, Wimberger P.

Br J Clin Pharmacol. 2015 Nov;80(5):1139-48. doi: 10.1111/bcp.12688. Epub 2015 Jul 22.

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