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Items: 1 to 50 of 225

1.

Amphotericin B Penetrates into the Central Nervous System Through Focal Disruption of the Blood Brain Barrier in Experimental Hematogenous Candida Meningoencephalitis.

Petraitis V, Petraitiene R, Valdez JM, Pyrgos V, Lizak MJ, Klaunberg BA, Kalasauskas D, Basevicius A, Bacher JD, Benjamin DK Jr, Hope WW, Walsh TJ.

Antimicrob Agents Chemother. 2019 Oct 7. pii: AAC.01626-19. doi: 10.1128/AAC.01626-19. [Epub ahead of print]

PMID:
31591128
2.

Discovery of a Potent and Selective Fragment-like Inhibitor of Methyllysine Reader Protein Spindlin 1 (SPIN1).

Xiong Y, Greschik H, Johansson C, Seifert L, Bacher J, Park KS, Babault N, Martini M, Fagan V, Li F, Chau I, Christott T, Dilworth D, Barsyte-Lovejoy D, Vedadi M, Arrowsmith CH, Brennan P, Fedorov O, Jung M, Farnie G, Liu J, Oppermann U, Schüle R, Jin J.

J Med Chem. 2019 Oct 24;62(20):8996-9007. doi: 10.1021/acs.jmedchem.9b00522. Epub 2019 Jul 24.

PMID:
31260300
3.

Sampling and weighting of the Austrian Psychiatric Prevalence Survey (APPS).

Alexandrowicz RW, Bacher J, Wancata J.

Neuropsychiatr. 2019 Jun;33(2):90-97. doi: 10.1007/s40211-019-0305-6. Epub 2019 Apr 3.

4.

Environmental remediation of sulfidic tailings with froth flotation: Reducing the consumption of additional resources by optimization of conditioning parameters and water recycling.

Nuorivaara T, Björkqvist A, Bacher J, Serna-Guerrero R.

J Environ Manage. 2019 Apr 15;236:125-133. doi: 10.1016/j.jenvman.2019.01.107. Epub 2019 Feb 2.

PMID:
30721830
5.

Assessment of Tumor Sequencing as a Replacement for Lynch Syndrome Screening and Current Molecular Tests for Patients With Colorectal Cancer.

Hampel H, Pearlman R, Beightol M, Zhao W, Jones D, Frankel WL, Goodfellow PJ, Yilmaz A, Miller K, Bacher J, Jacobson A, Paskett E, Shields PG, Goldberg RM, de la Chapelle A, Shirts BH, Pritchard CC; Ohio Colorectal Cancer Prevention Initiative Study Group.

JAMA Oncol. 2018 Jun 1;4(6):806-813. doi: 10.1001/jamaoncol.2018.0104. Erratum in: JAMA Oncol. 2018 Jun 1;4(6):891.

6.

Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer.

Pearlman R, Frankel WL, Swanson B, Zhao W, Yilmaz A, Miller K, Bacher J, Bigley C, Nelsen L, Goodfellow PJ, Goldberg RM, Paskett E, Shields PG, Freudenheim JL, Stanich PP, Lattimer I, Arnold M, Liyanarachchi S, Kalady M, Heald B, Greenwood C, Paquette I, Prues M, Draper DJ, Lindeman C, Kuebler JP, Reynolds K, Brell JM, Shaper AA, Mahesh S, Buie N, Weeman K, Shine K, Haut M, Edwards J, Bastola S, Wickham K, Khanduja KS, Zacks R, Pritchard CC, Shirts BH, Jacobson A, Allen B, de la Chapelle A, Hampel H; Ohio Colorectal Cancer Prevention Initiative Study Group.

JAMA Oncol. 2017 Apr 1;3(4):464-471. doi: 10.1001/jamaoncol.2016.5194.

7.

Liberation of Printed Circuit Assembly (PCA) and dust generation in relation to mobile phone design in a size reduction process.

Bachér J, Kaartinen T.

Waste Manag. 2017 Feb;60:609-617. doi: 10.1016/j.wasman.2016.09.037. Epub 2016 Oct 3.

PMID:
27712943
8.

Subclonal diversity arises early even in small colorectal tumours and contributes to differential growth fates.

Sievers CK, Zou LS, Pickhardt PJ, Matkowskyj KA, Albrecht DM, Clipson L, Bacher JW, Pooler BD, Moawad FJ, Cash BD, Reichelderfer M, Vo TN, Newton MA, Larget BR, Halberg RB.

Gut. 2017 Dec;66(12):2132-2140. doi: 10.1136/gutjnl-2016-312232. Epub 2016 Sep 8.

9.

Minimally Invasive Lumbar Port System for the Collection of Cerebrospinal Fluid from Rhesus Macaques (Macaca mulatta).

MacAllister RP, Lester McCully CM, Bacher J, Thomas ML III, Cruz R, Wangari S, Warren KE.

Comp Med. 2016;66(4):349-52.

10.

Microvascular Perfusion Changes following Transarterial Hepatic Tumor Embolization.

Johnson CG, Sharma KV, Levy EB, Woods DL, Morris AH, Bacher JD, Lewis AL, Wood BJ, Dreher MR.

J Vasc Interv Radiol. 2016 Jan;27(1):133-141.e3. doi: 10.1016/j.jvir.2015.06.036. Epub 2015 Aug 28.

11.

Improved Detection of Microsatellite Instability in Early Colorectal Lesions.

Bacher JW, Sievers CK, Albrecht DM, Grimes IC, Weiss JM, Matkowskyj KA, Agni RM, Vyazunova I, Clipson L, Storts DR, Thliveris AT, Halberg RB.

PLoS One. 2015 Aug 7;10(8):e0132727. doi: 10.1371/journal.pone.0132727. eCollection 2015.

12.

Direct Quantification and Comparison of Intratumoral Hypoxia following Transcatheter Arterial Embolization of VX2 Liver Tumors with Different Diameter Microspheres.

Levy EB, Gacchina Johnson C, Jacobs G, Woods DL, Sharma KV, Bacher JD, Lewis AL, Dreher MR, Wood BJ.

J Vasc Interv Radiol. 2015 Oct;26(10):1567-1573. doi: 10.1016/j.jvir.2015.06.011. Epub 2015 Jul 29.

PMID:
26231108
13.

Mechanical pre-treatment of mobile phones and its effect on the Printed Circuit Assemblies (PCAs).

Bachér J, Mrotzek A, Wahlström M.

Waste Manag. 2015 Nov;45:235-45. doi: 10.1016/j.wasman.2015.06.009. Epub 2015 Jun 29.

PMID:
26139137
14.

Effects of host response and antifungal therapy on serum and BAL levels of galactomannan and (1→3)-β-D-glucan in experimental invasive pulmonary aspergillosis.

Petraitiene R, Petraitis V, Bacher JD, Finkelman MA, Walsh TJ.

Med Mycol. 2015 Aug;53(6):558-68. doi: 10.1093/mmy/myv034. Epub 2015 Jun 30.

PMID:
26129890
15.

Development of a cerebrospinal fluid lateral reservoir model in rhesus monkeys (Macaca mulatta).

Lester McCully CM, Bacher J, MacAllister RP, Steffen-Smith EA, Saleem K, Thomas ML 3rd, Cruz R, Warren KE.

Comp Med. 2015 Feb;65(1):77-82.

16.

Planarian Phototactic Assay Reveals Differential Behavioral Responses Based on Wavelength.

Paskin TR, Jellies J, Bacher J, Beane WS.

PLoS One. 2014 Dec 10;9(12):e114708. doi: 10.1371/journal.pone.0114708. eCollection 2014.

17.

Impact of microsatellite instability on survival of endometrial cancer patients.

Kanopienė D, Smailytė G, Vidugirienė J, Bacher J.

Medicina (Kaunas). 2014;50(4):216-21. doi: 10.1016/j.medici.2014.09.002. Epub 2014 Sep 30.

18.

Endometrial cancer and microsatellite instability status.

Kanopiene D, Vidugiriene J, Valuckas KP, Smailyte G, Uleckiene S, Bacher J.

Open Med (Wars). 2014 Nov 11;10(1):70-76. doi: 10.1515/med-2015-0005. eCollection 2015.

19.

A non-human primate model of aneurismal subarachnoid hemorrhage (SAH).

Pluta RM, Bacher J, Skopets B, Hoffmann V.

Transl Stroke Res. 2014 Dec;5(6):681-91. doi: 10.1007/s12975-014-0371-9. Epub 2014 Sep 14.

PMID:
25216692
20.

Leukemogenesis in heterozygous PU.1 knockout mice.

Genik PC, Vyazunova I, Steffen LS, Bacher JW, Bielefeldt-Ohmann H, McKercher S, Ullrich RL, Fallgren CM, Weil MM, Ray FA.

Radiat Res. 2014 Sep;182(3):310-5. doi: 10.1667/RR13738.1. Epub 2014 Jul 30.

PMID:
25076114
21.

Polμ deficiency increases resistance to oxidative damage and delays liver aging.

Escudero B, Lucas D, Albo C, Dhup S, Bacher JW, Sánchez-Muñoz A, Fernández M, Rivera-Torres J, Carmona RM, Fuster E, Carreiro C, Bernad R, González MA, Andrés V, Blanco L, Roche E, Fabregat I, Samper E, Bernad A.

PLoS One. 2014 Apr 1;9(4):e93074. doi: 10.1371/journal.pone.0093074. eCollection 2014.

22.

Model for concomitant microdialysis sampling of the pons and cerebral cortex in rhesus macaques (Macaca mulatta).

McCully CM, Pastakia D, Bacher J, Thomas ML 3rd, Steffen-Smith EA, Saleem K, Murphy RF, Walbridge S, Brinster L, Widemann BC, Warren KE.

Comp Med. 2013 Aug;63(4):355-60.

23.

Autosomal dominant polycystic kidney disease: prevalence of renal neoplasias in surgical kidney specimens.

Jilg CA, Drendel V, Bacher J, Pisarski P, Neeff H, Drognitz O, Schwardt M, Gläsker S, Malinoc A, Erlic Z, Nunez M, Weber A, Azurmendi P, Schultze-Seemann W, Werner M, Neumann HP.

Nephron Clin Pract. 2013;123(1-2):13-21. doi: 10.1159/000351049. Epub 2013 Jun 4.

PMID:
23752029
24.

PIK3CA and APC mutations are synergistic in the development of intestinal cancers.

Deming DA, Leystra AA, Nettekoven L, Sievers C, Miller D, Middlebrooks M, Clipson L, Albrecht D, Bacher J, Washington MK, Weichert J, Halberg RB.

Oncogene. 2014 Apr 24;33(17):2245-54. doi: 10.1038/onc.2013.167. Epub 2013 May 27.

25.

Epidemiology of autosomal-dominant polycystic kidney disease: an in-depth clinical study for south-western Germany.

Neumann HP, Jilg C, Bacher J, Nabulsi Z, Malinoc A, Hummel B, Hoffmann MM, Ortiz-Bruechle N, Glasker S, Pisarski P, Neeff H, Krämer-Guth A, Cybulla M, Hornberger M, Wilpert J, Funk L, Baumert J, Paatz D, Baumann D, Lahl M, Felten H, Hausberg M, Zerres K, Eng C; Else-Kroener-Fresenius-ADPKD-Registry.

Nephrol Dial Transplant. 2013 Jun;28(6):1472-87. doi: 10.1093/ndt/gfs551. Epub 2013 Jan 8.

PMID:
23300259
26.

Characteristics of intracranial aneurysms in the else kröner-fresenius registry of autosomal dominant polycystic kidney disease.

Neumann HP, Malinoc A, Bacher J, Nabulsi Z, Ivanovas V, Bruechle NO, Mader I, Hoffmann MM, Riegler P, Kraemer-Guth A, Burchardi C, Schaeffner E, Martin RS, Azurmendi PJ, Zerres K, Jilg C, Eng C, Gläsker S.

Cerebrovasc Dis Extra. 2012 Jan;2(1):71-9. doi: 10.1159/000342620. Epub 2012 Oct 9.

27.

Molecular characterisation of murine acute myeloid leukaemia induced by 56Fe ion and 137Cs gamma ray irradiation.

Steffen LS, Bacher JW, Peng Y, Le PN, Ding LH, Genik PC, Ray FA, Bedford JS, Fallgren CM, Bailey SM, Ullrich RL, Weil MM, Story MD.

Mutagenesis. 2013 Jan;28(1):71-9. doi: 10.1093/mutage/ges055. Epub 2012 Sep 17.

28.

Increased virulence of Cunninghamella bertholletiae in experimental pulmonary mucormycosis: correlation with circulating molecular biomarkers, sporangiospore germination and hyphal metabolism.

Petraitis V, Petraitiene R, Antachopoulos C, Hughes JE, Cotton MP, Kasai M, Harrington S, Gamaletsou MN, Bacher JD, Kontoyiannis DP, Roilides E, Walsh TJ.

Med Mycol. 2013 Jan;51(1):72-82. doi: 10.3109/13693786.2012.690107. Epub 2012 Jun 11.

PMID:
22686246
29.

Stem cell-related markers in primary breast cancers and associated metastatic lesions.

Guler G, Balci S, Costinean S, Ussakli CH, Irkkan C, Suren D, Sari E, Altundag K, Ozisik Y, Jones S, Bacher J, Shapiro CL, Huebner K.

Mod Pathol. 2012 Jul;25(7):949-55. doi: 10.1038/modpathol.2012.37. Epub 2012 Mar 2.

30.

Adult patients with sporadic polycystic kidney disease: the importance of screening for mutations in the PKD1 and PKD2 genes.

Neumann HP, Bacher J, Nabulsi Z, Ortiz Brüchle N, Hoffmann MM, Schaeffner E, Nürnberger J, Cybulla M, Wilpert J, Riegler P, Corradini R, Kraemer-Guth A, Azurmendi P, Nunez M, Gläsker S, Zerres K, Jilg C.

Int Urol Nephrol. 2012 Dec;44(6):1753-62. doi: 10.1007/s11255-012-0125-0. Epub 2012 Feb 25.

PMID:
22367170
31.

Galactomannan antigenemia after infusion of gluconate-containing Plasma-Lyte.

Petraitiene R, Petraitis V, Witt JR 3rd, Durkin MM, Bacher JD, Wheat LJ, Walsh TJ.

J Clin Microbiol. 2011 Dec;49(12):4330-2. doi: 10.1128/JCM.05031-11. Epub 2011 Oct 5.

32.

Molecular detection and species-specific identification of medically important Aspergillus species by real-time PCR in experimental invasive pulmonary aspergillosis.

Walsh TJ, Wissel MC, Grantham KJ, Petraitiene R, Petraitis V, Kasai M, Francesconi A, Cotton MP, Hughes JE, Greene L, Bacher JD, Manna P, Salomoni M, Kleiboeker SB, Reddy SK.

J Clin Microbiol. 2011 Dec;49(12):4150-7. doi: 10.1128/JCM.00570-11. Epub 2011 Oct 5.

33.

Pyogenic granuloma of the foot with satellitosis: a role for conservative management.

Bacher J, Assaad D, Adam DN.

J Cutan Med Surg. 2011 Jan-Feb;15(1):58-60. Review.

PMID:
21291657
34.

Comparison of carbon dioxide and argon euthanasia: effects on behavior, heart rate, and respiratory lesions in rats.

Burkholder TH, Niel L, Weed JL, Brinster LR, Bacher JD, Foltz CJ.

J Am Assoc Lab Anim Sci. 2010 Jul;49(4):448-53.

35.

The initial 96 hours of invasive pulmonary aspergillosis: histopathology, comparative kinetics of galactomannan and (1->3) β-d-glucan and consequences of delayed antifungal therapy.

Hope WW, Petraitis V, Petraitiene R, Aghamolla T, Bacher J, Walsh TJ.

Antimicrob Agents Chemother. 2010 Nov;54(11):4879-86. doi: 10.1128/AAC.00673-10. Epub 2010 Aug 16.

36.

Systematic comparison of sporadic and syndromic pancreatic islet cell tumors.

Erlic Z, Ploeckinger U, Cascon A, Hoffmann MM, von Duecker L, Winter A, Kammel G, Bacher J, Sullivan M, Isermann B, Fischer L, Raffel A, Knoefel WT, Schott M, Baumann T, Schaefer O, Keck T, Baum RP, Milos I, Muresan M, Peczkowska M, Januszewicz A, Cupisti K, Tönjes A, Fasshauer M, Langrehr J, von Wussow P, Agaimy A, Schlimok G, Lamberts R, Wiech T, Schmid KW, Weber A, Nunez M, Robledo M, Eng C, Neumann HP; VHL-ICT Consortium; German NET Registry.

Endocr Relat Cancer. 2010 Oct 5;17(4):875-83. doi: 10.1677/ERC-10-0037. Print 2010 Dec.

PMID:
20660572
37.

Microsatellite instability in radiation-induced murine tumours; influence of tumour type and radiation quality.

Haines J, Bacher J, Coster M, Huiskamp R, Meijne E, Mancuso M, Pazzaglia S, Bouffler S.

Int J Radiat Biol. 2010 Jul;86(7):555-68. doi: 10.3109/09553001003734600.

PMID:
20545567
38.

Extracellular fluid concentrations of cisplatin, carboplatin, and oxaliplatin in brain, muscle, and blood measured using microdialysis in nonhuman primates.

Jacobs S, McCully CL, Murphy RF, Bacher J, Balis FM, Fox E.

Cancer Chemother Pharmacol. 2010 Apr;65(5):817-24. doi: 10.1007/s00280-009-1085-7. Epub 2009 Aug 7.

PMID:
19662415
39.

Long-lived Min mice develop advanced intestinal cancers through a genetically conservative pathway.

Halberg RB, Waggoner J, Rasmussen K, White A, Clipson L, Prunuske AJ, Bacher JW, Sullivan R, Washington MK, Pitot HC, Petrini JH, Albertson DG, Dove WF.

Cancer Res. 2009 Jul 15;69(14):5768-75. doi: 10.1158/0008-5472.CAN-09-0446. Epub 2009 Jul 7.

40.

BOWiki: an ontology-based wiki for annotation of data and integration of knowledge in biology.

Hoehndorf R, Bacher J, Backhaus M, Gregorio SE Jr, Loebe F, Prüfer K, Uciteli A, Visagie J, Herre H, Kelso J.

BMC Bioinformatics. 2009 May 6;10 Suppl 5:S5. doi: 10.1186/1471-2105-10-S5-S5.

41.

Copy number gain and oncogenic activity of YWHAZ/14-3-3zeta in head and neck squamous cell carcinoma.

Lin M, Morrison CD, Jones S, Mohamed N, Bacher J, Plass C.

Int J Cancer. 2009 Aug 1;125(3):603-11. doi: 10.1002/ijc.24346.

42.

Combination therapy in treatment of experimental pulmonary aspergillosis: in vitro and in vivo correlations of the concentration- and dose- dependent interactions between anidulafungin and voriconazole by Bliss independence drug interaction analysis.

Petraitis V, Petraitiene R, Hope WW, Meletiadis J, Mickiene D, Hughes JE, Cotton MP, Stergiopoulou T, Kasai M, Francesconi A, Schaufele RL, Sein T, Avila NA, Bacher J, Walsh TJ.

Antimicrob Agents Chemother. 2009 Jun;53(6):2382-91. doi: 10.1128/AAC.00329-09. Epub 2009 Mar 23.

43.

Diagnostic imaging of experimental invasive pulmonary aspergillosis.

Walsh TJ, Petraitis V, Petraitiene R, Solomon J, Bacher JD, Greene L, Cotton M, Groll A, Roilides E, Avila N, Pyrgos V, Shoham S.

Med Mycol. 2009;47 Suppl 1:S138-45. doi: 10.1080/13693780802665879. Epub 2009 Feb 27. Review.

PMID:
19253145
44.

Idiopathic chondrolysis condition in two young, wild-caught Cynomolgus monkeys (Macaca fascicularis) reared in captivity.

Rao S, Bryant M, Herbert R, Sullivan N, Murray C, Bacher J, Safdar N.

Vet Pathol. 2009 May;46(3):509-13. doi: 10.1354/vp.08-VP-0216-R-BC. Epub 2009 Jan 27.

PMID:
19176502
45.

Detection of a molecular biomarker for zygomycetes by quantitative PCR assays of plasma, bronchoalveolar lavage, and lung tissue in a rabbit model of experimental pulmonary zygomycosis.

Kasai M, Harrington SM, Francesconi A, Petraitis V, Petraitiene R, Beveridge MG, Knudsen T, Milanovich J, Cotton MP, Hughes J, Schaufele RL, Sein T, Bacher J, Murray PR, Kontoyiannis DP, Walsh TJ.

J Clin Microbiol. 2008 Nov;46(11):3690-702. doi: 10.1128/JCM.00917-08. Epub 2008 Sep 24.

46.

Cerebrospinal fluid and plasma (1-->3)-beta-D-glucan as surrogate markers for detection and monitoring of therapeutic response in experimental hematogenous Candida meningoencephalitis.

Petraitiene R, Petraitis V, Hope WW, Mickiene D, Kelaher AM, Murray HA, Mya-San C, Hughes JE, Cotton MP, Bacher J, Walsh TJ.

Antimicrob Agents Chemother. 2008 Nov;52(11):4121-9. doi: 10.1128/AAC.00674-08. Epub 2008 Sep 8.

47.

The pharmacokinetics and pharmacodynamics of micafungin in experimental hematogenous Candida meningoencephalitis: implications for echinocandin therapy in neonates.

Hope WW, Mickiene D, Petraitis V, Petraitiene R, Kelaher AM, Hughes JE, Cotton MP, Bacher J, Keirns JJ, Buell D, Heresi G, Benjamin DK Jr, Groll AH, Drusano GL, Walsh TJ.

J Infect Dis. 2008 Jan 1;197(1):163-71. doi: 10.1086/524063.

48.

Genetic code ambiguity confers a selective advantage on Acinetobacter baylyi.

Bacher JM, Waas WF, Metzgar D, de Crécy-Lagard V, Schimmel P.

J Bacteriol. 2007 Sep;189(17):6494-6. Epub 2007 Jul 6.

49.

An editing-defective aminoacyl-tRNA synthetase is mutagenic in aging bacteria via the SOS response.

Bacher JM, Schimmel P.

Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1907-12. Epub 2007 Jan 30.

50.

Pathogenesis of Aspergillus fumigatus and the kinetics of galactomannan in an in vitro model of early invasive pulmonary aspergillosis: implications for antifungal therapy.

Hope WW, Kruhlak MJ, Lyman CA, Petraitiene R, Petraitis V, Francesconi A, Kasai M, Mickiene D, Sein T, Peter J, Kelaher AM, Hughes JE, Cotton MP, Cotten CJ, Bacher J, Tripathi S, Bermudez L, Maugel TK, Zerfas PM, Wingard JR, Drusano GL, Walsh TJ.

J Infect Dis. 2007 Feb 1;195(3):455-66. Epub 2006 Dec 21.

PMID:
17205486

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