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Items: 1 to 50 of 71

1.

Islet Stellate Cells Isolated from Fibrotic Islet of Goto-Kakizaki Rats Affect Biological Behavior of Beta-Cell.

Li FF, Chen BJ, Li W, Li L, Zha M, Zhou S, Bachem MG, Sun ZL.

J Diabetes Res. 2016;2016:6924593. doi: 10.1155/2016/6924593. Epub 2015 Dec 1.

2.

Hexon modification to improve the activity of oncolytic adenovirus vectors against neoplastic and stromal cells in pancreatic cancer.

Lucas T, Benihoud K, Vigant F, Schmidt CQ, Wortmann A, Bachem MG, Simmet T, Kochanek S.

PLoS One. 2015 Feb 18;10(2):e0117254. doi: 10.1371/journal.pone.0117254. eCollection 2015. Erratum in: PLoS One. 2015;10(4):e0123844. Schmidt, Christoph Q Andreas [corrected to Schmidt, Christoph Q]; Wortmann, Andreas [added].

3.

INS-1 cells inhibit the production of extracellular matrix from pancreatic stellate cells.

Li F, Chen B, Li L, Zha M, Zhou S, Wu T, Bachem MG, Sun Z.

J Mol Histol. 2014 Jun;45(3):321-7. doi: 10.1007/s10735-013-9547-y. Epub 2013 Nov 8.

PMID:
24202436
4.

Pancreatic stellate cells promote hapto-migration of cancer cells through collagen I-mediated signalling pathway.

Lu J, Zhou S, Siech M, Habisch H, Seufferlein T, Bachem MG.

Br J Cancer. 2014 Jan 21;110(2):409-20. doi: 10.1038/bjc.2013.706. Epub 2013 Nov 7.

5.

Inhibition of NF-κB signaling ablates the invasive phenotype of glioblastoma.

Westhoff MA, Zhou S, Nonnenmacher L, Karpel-Massler G, Jennewein C, Schneider M, Halatsch ME, Carragher NO, Baumann B, Krause A, Simmet T, Bachem MG, Wirtz CR, Debatin KM.

Mol Cancer Res. 2013 Dec;11(12):1611-23. doi: 10.1158/1541-7786.MCR-13-0435-T. Epub 2013 Oct 21.

6.

Combined inhibition of HER1/EGFR and RAC1 results in a synergistic antiproliferative effect on established and primary cultured human glioblastoma cells.

Karpel-Massler G, Westhoff MA, Zhou S, Nonnenmacher L, Dwucet A, Kast RE, Bachem MG, Wirtz CR, Debatin KM, Halatsch ME.

Mol Cancer Ther. 2013 Sep;12(9):1783-95. doi: 10.1158/1535-7163.MCT-13-0052. Epub 2013 Jul 5.

7.

Role of activated neutrophils in chest trauma-induced septic acute lung injury.

Perl M, Hohmann C, Denk S, Kellermann P, Lu D, Braumüller S, Bachem MG, Thomas J, Knöferl MW, Ayala A, Gebhard F, Huber-Lang MS.

Shock. 2012 Jul;38(1):98-106. doi: 10.1097/SHK.0b013e318254be6a.

PMID:
22552016
8.

StellaTUM: current consensus and discussion on pancreatic stellate cell research.

Erkan M, Adler G, Apte MV, Bachem MG, Buchholz M, Detlefsen S, Esposito I, Friess H, Gress TM, Habisch HJ, Hwang RF, Jaster R, Kleeff J, Klöppel G, Kordes C, Logsdon CD, Masamune A, Michalski CW, Oh J, Phillips PA, Pinzani M, Reiser-Erkan C, Tsukamoto H, Wilson J.

Gut. 2012 Feb;61(2):172-8. doi: 10.1136/gutjnl-2011-301220. Epub 2011 Nov 24. No abstract available.

9.

Myofibroblast-induced tumorigenicity of pancreatic ductal epithelial cells is L1CAM dependent.

Schäfer H, Geismann C, Heneweer C, Egberts JH, Korniienko O, Kiefel H, Moldenhauer G, Bachem MG, Kalthoff H, Altevogt P, Sebens S.

Carcinogenesis. 2012 Jan;33(1):84-93. doi: 10.1093/carcin/bgr262. Epub 2011 Nov 17.

PMID:
22095073
10.

Divergent effects of activated neutrophils on inflammation, Kupffer cell/splenocyte activation, and lung injury following blunt chest trauma.

Perl M, Kieninger M, Huber-Lang MS, Gross HJ, Bachem MG, Braumüller S, Gebhard F, Ayala A, Knöferl MW.

Shock. 2012 Feb;37(2):210-8. doi: 10.1097/SHK.0b013e31823f1776.

PMID:
22089186
11.

Identification of c-FLIP(L) and c-FLIP(S) as critical regulators of death receptor-induced apoptosis in pancreatic cancer cells.

Haag C, Stadel D, Zhou S, Bachem MG, Möller P, Debatin KM, Fulda S.

Gut. 2011 Feb;60(2):225-37. doi: 10.1136/gut.2009.202325. Epub 2010 Sep 28.

PMID:
20876774
12.

PSP/reg inhibits cultured pancreatic stellate cell and regulates MMP/ TIMP ratio.

Li L, Bimmler D, Graf R, Zhou S, Sun Z, Chen J, Siech M, Bachem MG.

Eur J Clin Invest. 2011 Feb;41(2):151-8. doi: 10.1111/j.1365-2362.2010.02390.x. Epub 2010 Sep 23.

PMID:
20860757
13.

Interaction of stellate cells with pancreatic carcinoma cells.

Habisch H, Zhou S, Siech M, Bachem MG.

Cancers (Basel). 2010 Sep 9;2(3):1661-82. doi: 10.3390/cancers2031661.

14.

Stimulation of stellate cells by injured acinar cells: a model of acute pancreatitis induced by alcohol and fat (VLDL).

Siech M, Zhou Z, Zhou S, Bair B, Alt A, Hamm S, Gross H, Mayer J, Beger HG, Tian X, Kornmann M, Bachem MG.

Am J Physiol Gastrointest Liver Physiol. 2009 Dec;297(6):G1163-71. doi: 10.1152/ajpgi.90468.2008. Epub 2009 Sep 24.

15.

Up-regulation of L1CAM in pancreatic duct cells is transforming growth factor beta1- and slug-dependent: role in malignant transformation of pancreatic cancer.

Geismann C, Morscheck M, Koch D, Bergmann F, Ungefroren H, Arlt A, Tsao MS, Bachem MG, Altevogt P, Sipos B, Fölsch UR, Schäfer H, Müerköster SS.

Cancer Res. 2009 May 15;69(10):4517-26. doi: 10.1158/0008-5472.CAN-08-3493. Epub 2009 May 12.

16.

EMMPRIN (CD147) is a novel receptor for platelet GPVI and mediates platelet rolling via GPVI-EMMPRIN interaction.

Seizer P, Borst O, Langer HF, Bültmann A, Münch G, Herouy Y, Stellos K, Krämer B, Bigalke B, Büchele B, Bachem MG, Vestweber D, Simmet T, Gawaz M, May AE.

Thromb Haemost. 2009 Apr;101(4):682-6.

PMID:
19350111
17.

Pancreatitis-associated protein inhibits human pancreatic stellate cell MMP-1 and -2, TIMP-1 and -2 secretion and RECK expression.

Li L, Bachem MG, Zhou S, Sun Z, Chen J, Siech M, Bimmler D, Graf R.

Pancreatology. 2009;9(1-2):99-110. doi: 10.1159/000178880. Epub 2008 Dec 12.

PMID:
19077460
18.

Identification of a novel switch in the dominant forms of cell adhesion-mediated drug resistance in glioblastoma cells.

Westhoff MA, Zhou S, Bachem MG, Debatin KM, Fulda S.

Oncogene. 2008 Sep 4;27(39):5169-81. doi: 10.1038/onc.2008.148. Epub 2008 May 12.

PMID:
18469856
19.

Pulmonary contusion induces alveolar type 2 epithelial cell apoptosis: role of alveolar macrophages and neutrophils.

Seitz DH, Perl M, Mangold S, Neddermann A, Braumüller ST, Zhou S, Bachem MG, Huber-Lang MS, Knöferl MW.

Shock. 2008 Nov;30(5):537-44. doi: 10.1097/SHK.0b013e31816a394b.

PMID:
18317405
20.

Low intensity pulsed ultrasound accelerates macrophage phagocytosis by a pathway that requires actin polymerization, Rho, and Src/MAPKs activity.

Zhou S, Bachem MG, Seufferlein T, Li Y, Gross HJ, Schmelz A.

Cell Signal. 2008 Apr;20(4):695-704. doi: 10.1016/j.cellsig.2007.12.005. Epub 2007 Dec 14.

PMID:
18207700
21.

Pancreatic stellate cells--role in pancreas cancer.

Bachem MG, Zhou S, Buck K, Schneiderhan W, Siech M.

Langenbecks Arch Surg. 2008 Nov;393(6):891-900. doi: 10.1007/s00423-008-0279-5. Epub 2008 Jan 17. Review.

PMID:
18204855
22.

[Molecular mechanisms of low intensity pulsed ultrasound-mediated cellular behavior in human primary macrophages].

Li YP, Zhou SX, Schmelz A, Bachem MG.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2007 Dec;15(6):1253-6. Chinese.

PMID:
18088478
23.

Oxidized low density lipoproteins induce apoptosis in human lymphocytes: involvement of mitogen-activated protein kinases.

Bustamante M, Díaz F, Muñoz M, Gross HJ, Rivas CI, Llancaqueo A, Núñez L, Campos L, Kirsten L, Grandón J, González M, Barra V, Vera JC, Bachem MG.

Cell Mol Biol (Noisy-le-grand). 2007;53 Suppl:OL954-64.

PMID:
17695085
24.

Infiltration of blood outgrowth endothelial cells into tumor spheroids: role of matrix metalloproteinases and irradiation.

Wei J, Zhou S, Bachem MG, Debatin KM, Beltinger C.

Anticancer Res. 2007 May-Jun;27(3B):1415-21.

25.

Pancreatic stellate cells are an important source of MMP-2 in human pancreatic cancer and accelerate tumor progression in a murine xenograft model and CAM assay.

Schneiderhan W, Diaz F, Fundel M, Zhou S, Siech M, Hasel C, Möller P, Gschwend JE, Seufferlein T, Gress T, Adler G, Bachem MG.

J Cell Sci. 2007 Feb 1;120(Pt 3):512-9. Epub 2007 Jan 16.

26.

Role of stellate cells in pancreatic fibrogenesis associated with acute and chronic pancreatitis.

Bachem MG, Zhou Z, Zhou S, Siech M.

J Gastroenterol Hepatol. 2006 Oct;21 Suppl 3:S92-6. Review.

PMID:
16958683
27.

A very low toxic agent induces apoptosis and reduces growth of human hepatocellular carcinoma cells.

Schumacher G, Scheunert S, Rueggeberg A, Bachem MG, Nussler AK, Spinelli A, Mukhopadhyay T, Pratschke J, Neuhaus P.

J Gastroenterol Hepatol. 2006 Jul;21(7):1207-12.

PMID:
16824077
28.

Oxidized LDL inhibit hepatocyte growth factor synthesis in coronary smooth muscle cells.

Haug C, Lenz C, Bachem MG.

Int J Cardiol. 2005 Sep 1;103(3):298-306.

PMID:
16098393
29.

Transcriptome analysis of human hepatic and pancreatic stellate cells: organ-specific variations of a common transcriptional phenotype.

Buchholz M, Kestler HA, Holzmann K, Ellenrieder V, Schneiderhan W, Siech M, Adler G, Bachem MG, Gress TM.

J Mol Med (Berl). 2005 Oct;83(10):795-805. Epub 2005 Jun 23.

PMID:
15976918
30.

Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells.

Bachem MG, Schünemann M, Ramadani M, Siech M, Beger H, Buck A, Zhou S, Schmid-Kotsas A, Adler G.

Gastroenterology. 2005 Apr;128(4):907-21.

PMID:
15825074
31.

Molecular mechanisms of low intensity pulsed ultrasound in human skin fibroblasts.

Zhou S, Schmelz A, Seufferlein T, Li Y, Zhao J, Bachem MG.

J Biol Chem. 2004 Dec 24;279(52):54463-9. Epub 2004 Oct 12.

32.

Pancreatic tumor cells influence the composition of the extracellular matrix.

Köninger J, Giese T, di Mola FF, Wente MN, Esposito I, Bachem MG, Giese NA, Büchler MW, Friess H.

Biochem Biophys Res Commun. 2004 Sep 24;322(3):943-9.

PMID:
15336555
33.

Oxidized low-density lipoproteins stimulate extracellular matrix metalloproteinase Inducer (EMMPRIN) release by coronary smooth muscle cells.

Haug C, Lenz C, Díaz F, Bachem MG.

Arterioscler Thromb Vasc Biol. 2004 Oct;24(10):1823-9. Epub 2004 Aug 19.

PMID:
15319264
34.

Overexpressed decorin in pancreatic cancer: potential tumor growth inhibition and attenuation of chemotherapeutic action.

Köninger J, Giese NA, di Mola FF, Berberat P, Giese T, Esposito I, Bachem MG, Büchler MW, Friess H.

Clin Cancer Res. 2004 Jul 15;10(14):4776-83.

35.

Sensitivity and specificity of different staining methods to monitor apoptosis induced by oxidative stress in adherent cells.

Zhao J, Schmid-Kotsas A, Gross HJ, Gruenert A, Bachem MG.

Chin Med J (Engl). 2003 Dec;116(12):1923-9.

PMID:
14687485
36.
37.

Evaluation of two modified cardiac troponin I enzyme immunoassays.

Haug C, Bachem MG, Woehrle H, Hetzel M, Gruenert A.

Clin Chem Lab Med. 2002 Aug;40(8):837-9.

PMID:
12392315
38.

The immunosuppressive drug mycophenolic acid reduces endothelin-1 synthesis in endothelial cells and renal epithelial cells.

Haug C, Schmid-Kotsas A, Linder T, Jehle PM, Bachem MG, Gruenert A, Rozdzinski E.

Clin Sci (Lond). 2002 Aug;103 Suppl 48:76S-80S.

PMID:
12193059
39.

IL-10 receptor and coreceptor expression in quiescent and activated hepatic stellate cells.

Mathurin P, Xiong S, Kharbanda KK, Veal N, Miyahara T, Motomura K, Rippe RA, Bachem MG, Tsukamoto H.

Am J Physiol Gastrointest Liver Physiol. 2002 Jun;282(6):G981-90.

40.

Influence of hepatocyte growth factor, epidermal growth factor, and mycophenolic acid on endothelin-1 synthesis in human endothelial cells.

Haug C, Schmid-Kotsas A, Linder T, Bachem MG, Gruenert A, Rozdzinski E.

Nephrol Dial Transplant. 2001 Dec;16(12):2310-6.

PMID:
11733621
41.

Oxidized low-density lipoproteins bind to the scavenger receptor, CD36, of hepatic stellate cells and stimulate extracellular matrix synthesis.

Schneiderhan W, Schmid-Kotsas A, Zhao J, Grünert A, Nüssler A, Weidenbach H, Menke A, Schmid RM, Adler G, Bachem MG.

Hepatology. 2001 Oct;34(4 Pt 1):729-37.

PMID:
11584369
42.

Endothelin-1 synthesis and endothelin B receptor expression in human coronary artery smooth muscle cells and monocyte-derived macrophages is up-regulated by low density lipoproteins.

Haug C, Schmid-Kotsas A, Zorn U, Schuett S, Gross HJ, Gruenert A, Bachem MG.

J Mol Cell Cardiol. 2001 Sep;33(9):1701-12.

PMID:
11549348
43.

Identification of mediators stimulating proliferation and matrix synthesis of rat pancreatic stellate cells.

Schneider E, Schmid-Kotsas A, Zhao J, Weidenbach H, Schmid RM, Menke A, Adler G, Waltenberger J, Grünert A, Bachem MG.

Am J Physiol Cell Physiol. 2001 Aug;281(2):C532-43.

44.

Characterization of modified low density lipoprotein subfractions by capillary isotachophoresis.

Zorn U, Haug C, Celik E, Wennauer R, Schmid-Kotsas A, Bachem MG, Grünert A.

Electrophoresis. 2001 Apr;22(6):1143-9.

PMID:
11358140
45.

Hepatocyte growth factor is upregulated by low-density lipoproteins and inhibits endothelin-1 release.

Haug C, Schmid-Kotsas A, Zorn U, Bachem MG, Schuett S, Gruenert A, Rozdzinski E.

Am J Physiol Heart Circ Physiol. 2000 Dec;279(6):H2865-71.

46.

Platelet-derived growth factors stimulate proliferation and extracellular matrix synthesis of pancreatic stellate cells: implications in pathogenesis of pancreas fibrosis.

Luttenberger T, Schmid-Kotsas A, Menke A, Siech M, Beger H, Adler G, Grünert A, Bachem MG.

Lab Invest. 2000 Jan;80(1):47-55.

47.

Lipopolysaccharide-activated macrophages stimulate the synthesis of collagen type I and C-fibronectin in cultured pancreatic stellate cells.

Schmid-Kotsas A, Gross HJ, Menke A, Weidenbach H, Adler G, Siech M, Beger H, Grünert A, Bachem MG.

Am J Pathol. 1999 Nov;155(5):1749-58.

48.

Separation of lipoproteins by capillary isotachophoresis combined with enzymatic derivatization of cholesterol and triglycerides.

Zorn U, Wolf CF, Wennauer R, Bachem MG, Grünert A.

Electrophoresis. 1999 Jun;20(7):1619-26.

PMID:
10424488
49.
50.

Depending on their concentration oxidized low density lipoproteins stimulate extracellular matrix synthesis or induce apoptosis in human coronary artery smooth muscle cells.

Bachem MG, Wendelin D, Schneiderhan W, Haug C, Zorn U, Gross HJ, Schmid-Kotsas A, Grünert A.

Clin Chem Lab Med. 1999 Mar;37(3):319-26.

PMID:
10353478

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