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Items: 1 to 50 of 264

1.

Adenosine kinase attenuates cardiomyocyte microtubule stabilization and protects against pressure overload-induced hypertrophy and LV dysfunction.

Fassett J, Xu X, Kwak D, Zhu G, Fassett EK, Zhang P, Wang H, Mayer B, Bache RJ, Chen Y.

J Mol Cell Cardiol. 2019 May;130:49-58. doi: 10.1016/j.yjmcc.2019.03.015. Epub 2019 Mar 22.

PMID:
30910669
2.

Hints of Lyme: Disseminated Borreliosis Involving the Mitral and Tricuspid Valves.

Maheshwari A, Bache RJ.

Am J Med. 2017 Oct;130(10):e441-e442. doi: 10.1016/j.amjmed.2017.04.036. Epub 2017 May 19. No abstract available.

PMID:
28532987
3.

Role of bone marrow-derived CD11c+ dendritic cells in systolic overload-induced left ventricular inflammation, fibrosis and hypertrophy.

Wang H, Kwak D, Fassett J, Liu X, Yao W, Weng X, Xu X, Xu Y, Bache RJ, Mueller DL, Chen Y.

Basic Res Cardiol. 2017 May;112(3):25. doi: 10.1007/s00395-017-0615-4. Epub 2017 Mar 27.

4.

Repetitive ischemia increases myocardial dimethylarginine dimethylaminohydrolase 1 expression.

Zhang P, Fassett JT, Zhu G, Li J, Hu X, Xu X, Chen Y, Bache RJ.

Vasc Med. 2017 Jun;22(3):179-188. doi: 10.1177/1358863X16681215. Epub 2017 Feb 1.

PMID:
28145161
5.

A Novel Method for Assessing Cardiac Output With the Use of Oxygen Circulation Time.

Kwon Y, Van't Hof J, Roy SS, Bache RJ, Das G.

J Card Fail. 2016 Nov;22(11):921-924. doi: 10.1016/j.cardfail.2015.10.021. Epub 2015 Nov 10.

PMID:
26571148
6.

CD28/B7 Deficiency Attenuates Systolic Overload-Induced Congestive Heart Failure, Myocardial and Pulmonary Inflammation, and Activated T Cell Accumulation in the Heart and Lungs.

Wang H, Kwak D, Fassett J, Hou L, Xu X, Burbach BJ, Thenappan T, Xu Y, Ge JB, Shimizu Y, Bache RJ, Chen Y.

Hypertension. 2016 Sep;68(3):688-96. doi: 10.1161/HYPERTENSIONAHA.116.07579. Epub 2016 Jul 18.

7.

Increasing Regulatory T Cells With Interleukin-2 and Interleukin-2 Antibody Complexes Attenuates Lung Inflammation and Heart Failure Progression.

Wang H, Hou L, Kwak D, Fassett J, Xu X, Chen A, Chen W, Blazar BR, Xu Y, Hall JL, Ge JB, Bache RJ, Chen Y.

Hypertension. 2016 Jul;68(1):114-22. doi: 10.1161/HYPERTENSIONAHA.116.07084. Epub 2016 May 9.

8.

ATP sensitive K(+) channels are critical for maintaining myocardial perfusion and high energy phosphates in the failing heart.

Jameel MN, Xiong Q, Mansoor A, Bache RJ, Zhang J.

J Mol Cell Cardiol. 2016 Mar;92:116-21. doi: 10.1016/j.yjmcc.2016.02.005. Epub 2016 Feb 20.

9.

Endoplasmic reticulum stress sensor protein kinase R-like endoplasmic reticulum kinase (PERK) protects against pressure overload-induced heart failure and lung remodeling.

Liu X, Kwak D, Lu Z, Xu X, Fassett J, Wang H, Wei Y, Cavener DR, Hu X, Hall J, Bache RJ, Chen Y.

Hypertension. 2014 Oct;64(4):738-44. doi: 10.1161/HYPERTENSIONAHA.114.03811. Epub 2014 Jun 23.

10.

NOX2-induced myocardial fibrosis and diastolic dysfunction: role of the endothelium.

Bache RJ, Chen Y.

J Am Coll Cardiol. 2014 Jun 24;63(24):2742-4. doi: 10.1016/j.jacc.2014.01.070. Epub 2014 Mar 26. No abstract available.

11.

Double-stranded RNA-dependent protein kinase deficiency protects the heart from systolic overload-induced congestive heart failure.

Wang H, Xu X, Fassett J, Kwak D, Liu X, Hu X, Falls TJ, Bell JC, Li H, Bitterman P, Bache RJ, Chen Y.

Circulation. 2014 Apr 1;129(13):1397-406. doi: 10.1161/CIRCULATIONAHA.113.002209. Epub 2014 Jan 24.

12.

Metformin protects against systolic overload-induced heart failure independent of AMP-activated protein kinase α2.

Xu X, Lu Z, Fassett J, Zhang P, Hu X, Liu X, Kwak D, Li J, Zhu G, Tao Y, Hou M, Wang H, Guo H, Viollet B, McFalls EO, Bache RJ, Chen Y.

Hypertension. 2014 Apr;63(4):723-8. doi: 10.1161/HYPERTENSIONAHA.113.02619. Epub 2014 Jan 13.

13.

Inducible nitric oxide synthase inhibits oxygen consumption in collateral-dependent myocardium.

Chen Y, Zhang P, Li J, Xu X, Bache RJ.

Am J Physiol Heart Circ Physiol. 2014 Feb;306(3):H356-62. doi: 10.1152/ajpheart.00308.2013. Epub 2013 Dec 6.

14.

DDAH1 deficiency attenuates endothelial cell cycle progression and angiogenesis.

Zhang P, Xu X, Hu X, Wang H, Fassett J, Huo Y, Chen Y, Bache RJ.

PLoS One. 2013 Nov 18;8(11):e79444. doi: 10.1371/journal.pone.0079444. eCollection 2013.

15.

Loss of the eukaryotic initiation factor 2α kinase general control nonderepressible 2 protects mice from pressure overload-induced congestive heart failure without affecting ventricular hypertrophy.

Lu Z, Xu X, Fassett J, Kwak D, Liu X, Hu X, Wang H, Guo H, Xu D, Yan S, McFalls EO, Lu F, Bache RJ, Chen Y.

Hypertension. 2014 Jan;63(1):128-35. doi: 10.1161/HYPERTENSIONAHA.113.02313. Epub 2013 Oct 28.

16.

Microtubule Actin Cross-linking Factor 1 regulates cardiomyocyte microtubule distribution and adaptation to hemodynamic overload.

Fassett JT, Xu X, Kwak D, Wang H, Liu X, Hu X, Bache RJ, Chen Y.

PLoS One. 2013 Sep 26;8(9):e73887. doi: 10.1371/journal.pone.0073887. eCollection 2013.

17.

AMPK attenuates microtubule proliferation in cardiac hypertrophy.

Fassett JT, Hu X, Xu X, Lu Z, Zhang P, Chen Y, Bache RJ.

Am J Physiol Heart Circ Physiol. 2013 Mar 1;304(5):H749-58. doi: 10.1152/ajpheart.00935.2011. Epub 2013 Jan 11.

18.

Peripheral circulation.

Laughlin MH, Davis MJ, Secher NH, van Lieshout JJ, Arce-Esquivel AA, Simmons GH, Bender SB, Padilla J, Bache RJ, Merkus D, Duncker DJ.

Compr Physiol. 2012 Jan;2(1):321-447. doi: 10.1002/cphy.c100048. Review.

PMID:
23728977
19.

Regulation of coronary resistance vessel tone in response to exercise.

Duncker DJ, Bache RJ, Merkus D.

J Mol Cell Cardiol. 2012 Apr;52(4):802-13. doi: 10.1016/j.yjmcc.2011.10.007. Epub 2011 Oct 15. Review.

PMID:
22037538
20.

AMP activated protein kinase-α2 regulates expression of estrogen-related receptor-α, a metabolic transcription factor related to heart failure development.

Hu X, Xu X, Lu Z, Zhang P, Fassett J, Zhang Y, Xin Y, Hall JL, Viollet B, Bache RJ, Huang Y, Chen Y.

Hypertension. 2011 Oct;58(4):696-703. doi: 10.1161/HYPERTENSIONAHA.111.174128. Epub 2011 Aug 8.

21.

Exacerbated pulmonary arterial hypertension and right ventricular hypertrophy in animals with loss of function of extracellular superoxide dismutase.

Xu D, Guo H, Xu X, Lu Z, Fassett J, Hu X, Xu Y, Tang Q, Hu D, Somani A, Geurts AM, Ostertag E, Bache RJ, Weir EK, Chen Y.

Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5.

22.

Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine.

Hu X, Atzler D, Xu X, Zhang P, Guo H, Lu Z, Fassett J, Schwedhelm E, Böger RH, Bache RJ, Chen Y.

Arterioscler Thromb Vasc Biol. 2011 Jul;31(7):1540-6. doi: 10.1161/ATVBAHA.110.222638. Epub 2011 Apr 14.

23.

Adenosine kinase regulation of cardiomyocyte hypertrophy.

Fassett JT, Hu X, Xu X, Lu Z, Zhang P, Chen Y, Bache RJ.

Am J Physiol Heart Circ Physiol. 2011 May;300(5):H1722-32. doi: 10.1152/ajpheart.00684.2010. Epub 2011 Feb 18.

24.

Dimethylarginine dimethylaminohydrolase 1 modulates endothelial cell growth through nitric oxide and Akt.

Zhang P, Hu X, Xu X, Chen Y, Bache RJ.

Arterioscler Thromb Vasc Biol. 2011 Apr;31(4):890-7. doi: 10.1161/ATVBAHA.110.215640. Epub 2011 Jan 6.

25.

Adenosine regulation of microtubule dynamics in cardiac hypertrophy.

Fassett JT, Xu X, Hu X, Zhu G, French J, Chen Y, Bache RJ.

Am J Physiol Heart Circ Physiol. 2009 Aug;297(2):H523-32. doi: 10.1152/ajpheart.00462.2009. Epub 2009 Jun 12.

26.

NADPH oxidase contributes to coronary endothelial dysfunction in the failing heart.

Zhang P, Hou M, Li Y, Xu X, Barsoum M, Chen Y, Bache RJ.

Am J Physiol Heart Circ Physiol. 2009 Mar;296(3):H840-6. doi: 10.1152/ajpheart.00519.2008. Epub 2009 Jan 23.

27.

Xanthine oxidase inhibition with febuxostat attenuates systolic overload-induced left ventricular hypertrophy and dysfunction in mice.

Xu X, Hu X, Lu Z, Zhang P, Zhao L, Wessale JL, Bache RJ, Chen Y.

J Card Fail. 2008 Nov;14(9):746-53. doi: 10.1016/j.cardfail.2008.06.006. Epub 2008 Jul 10.

28.

AMP activated protein kinase-alpha2 deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction in mice.

Zhang P, Hu X, Xu X, Fassett J, Zhu G, Viollet B, Xu W, Wiczer B, Bernlohr DA, Bache RJ, Chen Y.

Hypertension. 2008 Nov;52(5):918-24. doi: 10.1161/HYPERTENSIONAHA.108.114702. Epub 2008 Oct 6.

29.

Adenosine A3 receptor deficiency exerts unanticipated protective effects on the pressure-overloaded left ventricle.

Lu Z, Fassett J, Xu X, Hu X, Zhu G, French J, Zhang P, Schnermann J, Bache RJ, Chen Y.

Circulation. 2008 Oct 21;118(17):1713-21. doi: 10.1161/CIRCULATIONAHA.108.788307. Epub 2008 Oct 6.

30.

Disruption of sarcolemmal ATP-sensitive potassium channel activity impairs the cardiac response to systolic overload.

Hu X, Xu X, Huang Y, Fassett J, Flagg TP, Zhang Y, Nichols CG, Bache RJ, Chen Y.

Circ Res. 2008 Oct 24;103(9):1009-17. doi: 10.1161/CIRCRESAHA.107.170795. Epub 2008 Sep 18.

31.

Regulation of coronary blood flow during exercise.

Duncker DJ, Bache RJ.

Physiol Rev. 2008 Jul;88(3):1009-86. doi: 10.1152/physrev.00045.2006. Review.

32.

Phosphate metabolite concentrations and ATP hydrolysis potential in normal and ischaemic hearts.

Wu F, Zhang EY, Zhang J, Bache RJ, Beard DA.

J Physiol. 2008 Sep 1;586(17):4193-208. doi: 10.1113/jphysiol.2008.154732. Epub 2008 Jul 10.

33.

Ecto-5'-nucleotidase deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction.

Xu X, Fassett J, Hu X, Zhu G, Lu Z, Li Y, Schnermann J, Bache RJ, Chen Y.

Hypertension. 2008 Jun;51(6):1557-64. doi: 10.1161/HYPERTENSIONAHA.108.110833. Epub 2008 Apr 7.

34.

Extracellular superoxide dismutase protects the heart against oxidative stress and hypertrophy after myocardial infarction.

van Deel ED, Lu Z, Xu X, Zhu G, Hu X, Oury TD, Bache RJ, Duncker DJ, Chen Y.

Free Radic Biol Med. 2008 Apr 1;44(7):1305-13. doi: 10.1016/j.freeradbiomed.2007.12.007. Epub 2007 Dec 15.

35.

Extracellular superoxide dismutase deficiency exacerbates pressure overload-induced left ventricular hypertrophy and dysfunction.

Lu Z, Xu X, Hu X, Zhu G, Zhang P, van Deel ED, French JP, Fassett JT, Oury TD, Bache RJ, Chen Y.

Hypertension. 2008 Jan;51(1):19-25. Epub 2007 Nov 12.

36.

Endothelial nitric oxide synthase is dynamically expressed during bone marrow stem cell differentiation into endothelial cells.

Liu Z, Jiang Y, Hao H, Gupta K, Xu J, Chu L, McFalls E, Zweier J, Verfaillie C, Bache RJ.

Am J Physiol Heart Circ Physiol. 2007 Sep;293(3):H1760-5. Epub 2007 Jun 1.

37.

Effect of K+ATP channel and adenosine receptor blockade during rest and exercise in congestive heart failure.

Traverse JH, Chen Y, Hou M, Li Y, Bache RJ.

Circ Res. 2007 Jun 8;100(11):1643-9. Epub 2007 May 3.

PMID:
17478726
38.

Bioenergetic and functional consequences of bone marrow-derived multipotent progenitor cell transplantation in hearts with postinfarction left ventricular remodeling.

Zeng L, Hu Q, Wang X, Mansoor A, Lee J, Feygin J, Zhang G, Suntharalingam P, Boozer S, Mhashilkar A, Panetta CJ, Swingen C, Deans R, From AH, Bache RJ, Verfaillie CM, Zhang J.

Circulation. 2007 Apr 10;115(14):1866-75. Epub 2007 Mar 26.

PMID:
17389266
39.

Acute effects of febuxostat, a nonpurine selective inhibitor of xanthine oxidase, in pacing induced heart failure.

Hou M, Hu Q, Chen Y, Zhao L, Zhang J, Bache RJ.

J Cardiovasc Pharmacol. 2006 Nov;48(5):255-63.

PMID:
17110808
40.

Profound bioenergetic abnormalities in peri-infarct myocardial regions.

Hu Q, Wang X, Lee J, Mansoor A, Liu J, Zeng L, Swingen C, Zhang G, Feygin J, Ochiai K, Bransford TL, From AH, Bache RJ, Zhang J.

Am J Physiol Heart Circ Physiol. 2006 Aug;291(2):H648-57. Epub 2006 Mar 31.

41.

Measurement of myocardial free radical production during exercise using EPR spectroscopy.

Traverse JH, Nesmelov YE, Crampton M, Lindstrom P, Thomas DD, Bache RJ.

Am J Physiol Heart Circ Physiol. 2006 Jun;290(6):H2453-8. Epub 2006 Jan 13. Erratum in: Am J Physiol Heart Circ Physiol. 2006 Nov;291(5):H2554.

42.

Dimethylarginine dimethylaminohydrolase and endothelial dysfunction in failing hearts.

Chen Y, Li Y, Zhang P, Traverse JH, Hou M, Xu X, Kimoto M, Bache RJ.

Am J Physiol Heart Circ Physiol. 2005 Nov;289(5):H2212-9. Epub 2005 Jul 15.

43.

Increased superoxide production causes coronary endothelial dysfunction and depressed oxygen consumption in the failing heart.

Chen Y, Hou M, Li Y, Traverse JH, Zhang P, Salvemini D, Fukai T, Bache RJ.

Am J Physiol Heart Circ Physiol. 2005 Jan;288(1):H133-41.

44.

Nitric oxide regulation of myocardial O2 consumption and HEP metabolism.

Zhang J, Gong G, Ye Y, Guo T, Mansoor A, Hu Q, Ochiai K, Liu J, Wang X, Cheng Y, Iverson N, Lee J, From AH, Ugurbil K, Bache RJ.

Am J Physiol Heart Circ Physiol. 2005 Jan;288(1):H310-6. Epub 2004 Sep 16.

45.

Activation of p38 MAPK and increased glucose transport in chronic hibernating swine myocardium.

McFalls EO, Hou M, Bache RJ, Best A, Marx D, Sikora J, Ward HB.

Am J Physiol Heart Circ Physiol. 2004 Sep;287(3):H1328-34.

46.

Autologous stem cell transplantation for myocardial repair.

Liu J, Hu Q, Wang Z, Xu C, Wang X, Gong G, Mansoor A, Lee J, Hou M, Zeng L, Zhang JR, Jerosch-Herold M, Guo T, Bache RJ, Zhang J.

Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H501-11.

47.

ET-A receptor activity restrains coronary blood flow in the failing heart.

Hou M, Chen Y, Traverse JH, Li Y, Barsoum M, Bache RJ.

J Cardiovasc Pharmacol. 2004 Jun;43(6):764-9.

PMID:
15167269
48.

Genomic profiling of the human heart before and after mechanical support with a ventricular assist device reveals alterations in vascular signaling networks.

Hall JL, Grindle S, Han X, Fermin D, Park S, Chen Y, Bache RJ, Mariash A, Guan Z, Ormaza S, Thompson J, Graziano J, de Sam Lazaro SE, Pan S, Simari RD, Miller LW.

Physiol Genomics. 2004 May 19;17(3):283-91.

PMID:
14872006
49.

Adenosine: a modulator of the cardiac response to stress.

Chen Y, Bache RJ.

Circ Res. 2003 Oct 17;93(8):691-3. No abstract available.

PMID:
14563707
50.

Alterations of gene expression in failing myocardium following left ventricular assist device support.

Chen Y, Park S, Li Y, Missov E, Hou M, Han X, Hall JL, Miller LW, Bache RJ.

Physiol Genomics. 2003 Aug 15;14(3):251-60.

PMID:
12824457

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