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Items: 47


Predicting Phenotypic Diversity from Molecular and Genetic Data.

Harel T, Peshes-Yaloz N, Bacharach E, Gat-Viks I.

Genetics. 2019 Sep;213(1):297-311. doi: 10.1534/genetics.119.302463. Epub 2019 Jul 27.


Cell composition analysis of bulk genomics using single-cell data.

Frishberg A, Peshes-Yaloz N, Cohn O, Rosentul D, Steuerman Y, Valadarsky L, Yankovitz G, Mandelboim M, Iraqi FA, Amit I, Mayo L, Bacharach E, Gat-Viks I.

Nat Methods. 2019 Apr;16(4):327-332. doi: 10.1038/s41592-019-0355-5. Epub 2019 Mar 18.


Dissection of Influenza Infection In Vivo by Single-Cell RNA Sequencing.

Steuerman Y, Cohen M, Peshes-Yaloz N, Valadarsky L, Cohn O, David E, Frishberg A, Mayo L, Bacharach E, Amit I, Gat-Viks I.

Cell Syst. 2018 Jun 27;6(6):679-691.e4. doi: 10.1016/j.cels.2018.05.008. Epub 2018 Jun 6.


Interleukin-6 and Interferon-α Signaling via JAK1-STAT Differentially Regulate Oncolytic versus Cytoprotective Antiviral States.

Danziger O, Pupko T, Bacharach E, Ehrlich M.

Front Immunol. 2018 Jan 30;9:94. doi: 10.3389/fimmu.2018.00094. eCollection 2018.


NK-cell receptors NKp46 and NCR1 control human metapneumovirus infection.

Diab M, Glasner A, Isaacson B, Bar-On Y, Drori Y, Yamin R, Duev-Cohen A, Danziger O, Zamostiano R, Mandelboim M, Jonjic S, Bacharach E, Mandelboim O.

Eur J Immunol. 2017 Apr;47(4):692-703. doi: 10.1002/eji.201646756. Epub 2017 Mar 6.


Detection of Tilapia Lake Virus in Clinical Samples by Culturing and Nested Reverse Transcription-PCR.

Kembou Tsofack JE, Zamostiano R, Watted S, Berkowitz A, Rosenbluth E, Mishra N, Briese T, Lipkin WI, Kabuusu RM, Ferguson H, Del Pozo J, Eldar A, Bacharach E.

J Clin Microbiol. 2017 Mar;55(3):759-767. doi: 10.1128/JCM.01808-16. Epub 2016 Dec 14.


Suppression of human metapneumovirus (HMPV) infection by the innate sensing gene CEACAM1.

Diab M, Vitenshtein A, Drori Y, Yamin R, Danziger O, Zamostiano R, Mandelboim M, Bacharach E, Mandelboim O.

Oncotarget. 2016 Oct 11;7(41):66468-66479. doi: 10.18632/oncotarget.11979.


Syncytial Hepatitis of Tilapia ( Oreochromis niloticus L.) is Associated With Orthomyxovirus-Like Virions in Hepatocytes.

Del-Pozo J, Mishra N, Kabuusu R, Cheetham S, Eldar A, Bacharach E, Lipkin WI, Ferguson HW.

Vet Pathol. 2017 Jan;54(1):164-170. doi: 10.1177/0300985816658100. Epub 2016 Aug 20.


Combined genetic and epigenetic interferences with interferon signaling expose prostate cancer cells to viral infection.

Danziger O, Shai B, Sabo Y, Bacharach E, Ehrlich M.

Oncotarget. 2016 Aug 9;7(32):52115-52134. doi: 10.18632/oncotarget.10313.


Characterization of a Novel Orthomyxo-like Virus Causing Mass Die-Offs of Tilapia.

Bacharach E, Mishra N, Briese T, Zody MC, Kembou Tsofack JE, Zamostiano R, Berkowitz A, Ng J, Nitido A, Corvelo A, Toussaint NC, Abel Nielsen SC, Hornig M, Del Pozo J, Bloom T, Ferguson H, Eldar A, Lipkin WI.

MBio. 2016 Apr 5;7(2):e00431-16. doi: 10.1128/mBio.00431-16.


Dynamics and restriction of murine leukemia virus cores in mitotic and interphase cells.

Elis E, Ehrlich M, Bacharach E.

Retrovirology. 2015 Nov 14;12:95. doi: 10.1186/s12977-015-0220-2.


α-Aminoisobutyric acid incorporation induces cell permeability and antiviral activity of HIV-1 major homology region fragments.

Lampel A, Elis E, Guterman T, Shapira S, Marco P, Bacharach E, Gazit E.

Chem Commun (Camb). 2015 Aug 11;51(62):12349-52. doi: 10.1039/c5cc01421b.


Targeting the Early Step of Building Block Organization in Viral Capsid Assembly.

Lampel A, Bram Y, Ezer A, Shaltiel-Kario R, Saad JS, Bacharach E, Gazit E.

ACS Chem Biol. 2015 Aug 21;10(8):1785-90. doi: 10.1021/acschembio.5b00347. Epub 2015 May 29.


New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein.

Kipper S, Hamad S, Caly L, Avrahami D, Bacharach E, Jans DA, Gerber D, Bajorek M.

Mol Cell Proteomics. 2015 Mar;14(3):532-43. doi: 10.1074/mcp.M114.044107. Epub 2015 Jan 2.


The N-terminus of murine leukaemia virus p12 protein is required for mature core stability.

Wight DJ, Boucherit VC, Wanaguru M, Elis E, Hirst EM, Li W, Ehrlich M, Bacharach E, Bishop KN.

PLoS Pathog. 2014 Oct 30;10(10):e1004474. doi: 10.1371/journal.ppat.1004474. eCollection 2014 Oct.


Identification of a novel RNA virus lethal to tilapia.

Eyngor M, Zamostiano R, Kembou Tsofack JE, Berkowitz A, Bercovier H, Tinman S, Lev M, Hurvitz A, Galeotti M, Bacharach E, Eldar A.

J Clin Microbiol. 2014 Dec;52(12):4137-46. doi: 10.1128/JCM.00827-14. Epub 2014 Sep 17.


The Thr205 phosphorylation site within respiratory syncytial virus matrix (M) protein modulates M oligomerization and virus production.

Bajorek M, Caly L, Tran KC, Maertens GN, Tripp RA, Bacharach E, Teng MN, Ghildyal R, Jans DA.

J Virol. 2014 Jun;88(11):6380-93. doi: 10.1128/JVI.03856-13. Epub 2014 Mar 26.


Epizootic hemorrhagic disease virus induces and benefits from cell stress, autophagy, and apoptosis.

Shai B, Schmukler E, Yaniv R, Ziv N, Horn G, Bumbarov V, Yadin H, Smorodinsky NI, Bacharach E, Pinkas-Kramarski R, Ehrlich M.

J Virol. 2013 Dec;87(24):13397-408. doi: 10.1128/JVI.02116-13. Epub 2013 Oct 2.


Synonymous site conservation in the HIV-1 genome.

Mayrose I, Stern A, Burdelova EO, Sabo Y, Laham-Karam N, Zamostiano R, Bacharach E, Pupko T.

BMC Evol Biol. 2013 Aug 4;13:164. doi: 10.1186/1471-2148-13-164.


A triclinic crystal structure of the carboxy-terminal domain of HIV-1 capsid protein with four molecules in the asymmetric unit reveals a novel packing interface.

Lampel A, Yaniv O, Berger O, Bacharach E, Gazit E, Frolow F.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jun;69(Pt 6):602-6. doi: 10.1107/S1744309113011871. Epub 2013 May 23.


The effect of chemical chaperones on the assembly and stability of HIV-1 capsid protein.

Lampel A, Bram Y, Levy-Sakin M, Bacharach E, Gazit E.

PLoS One. 2013;8(4):e60867. doi: 10.1371/journal.pone.0060867. Epub 2013 Apr 5.


p12 tethers the murine leukemia virus pre-integration complex to mitotic chromosomes.

Elis E, Ehrlich M, Prizan-Ravid A, Laham-Karam N, Bacharach E.

PLoS Pathog. 2012 Dec;8(12):e1003103. doi: 10.1371/journal.ppat.1003103. Epub 2012 Dec 27.


Human immunodeficiency virus type 1 envelope proteins traffic toward virion assembly sites via a TBC1D20/Rab1-regulated pathway.

Nachmias D, Sklan EH, Ehrlich M, Bacharach E.

Retrovirology. 2012 Jan 19;9:7. doi: 10.1186/1742-4690-9-7.


The conserved YAGL motif in human metapneumovirus is required for higher-order cellular assemblies of the matrix protein and for virion production.

Sabo Y, Ehrlich M, Bacharach E.

J Virol. 2011 Jul;85(13):6594-609. doi: 10.1128/JVI.02694-10. Epub 2011 Apr 27.


The Gag cleavage product, p12, is a functional constituent of the murine leukemia virus pre-integration complex.

Prizan-Ravid A, Elis E, Laham-Karam N, Selig S, Ehrlich M, Bacharach E.

PLoS Pathog. 2010 Nov 11;6(11):e1001183. doi: 10.1371/journal.ppat.1001183.


Longitudinal survey of avian metapneumoviruses in poultry in Israel: infiltration of field strains into vaccinated flocks.

Banet-Noach C, Simanov L, Laham-Karam N, Perk S, Bacharach E.

Avian Dis. 2009 Jun;53(2):184-9.


Evolutionary modeling of rate shifts reveals specificity determinants in HIV-1 subtypes.

Penn O, Stern A, Rubinstein ND, Dutheil J, Bacharach E, Galtier N, Pupko T.

PLoS Comput Biol. 2008 Nov;4(11):e1000214. doi: 10.1371/journal.pcbi.1000214. Epub 2008 Nov 7.


Basal budding and replication of the murine leukemia virus are independent of the gag L domains.

Sabo Y, Laham-Karam N, Bacharach E.

J Virol. 2008 Oct;82(19):9770-5. doi: 10.1128/JVI.00741-08. Epub 2008 Jul 30.


Phenolsulfonphthalein, but not phenolphthalein, inhibits amyloid fibril formation: implications for the modulation of amyloid self-assembly.

Levy M, Porat Y, Bacharach E, Shalev DE, Gazit E.

Biochemistry. 2008 Jun 3;47(22):5896-904. doi: 10.1021/bi800043d. Epub 2008 May 6.


Transduction of human immunodeficiency virus type 1 vectors lacking encapsidation and dimerization signals.

Laham-Karam N, Bacharach E.

J Virol. 2007 Oct;81(19):10687-98. Epub 2007 Jul 25.


Towards realistic codon models: among site variability and dependency of synonymous and non-synonymous rates.

Mayrose I, Doron-Faigenboim A, Bacharach E, Pupko T.

Bioinformatics. 2007 Jul 1;23(13):i319-27.


Selecton 2007: advanced models for detecting positive and purifying selection using a Bayesian inference approach.

Stern A, Doron-Faigenboim A, Erez E, Martz E, Bacharach E, Pupko T.

Nucleic Acids Res. 2007 Jul;35(Web Server issue):W506-11. Epub 2007 Jun 22.


Mouse major satellite DNA is prone to eccDNA formation via DNA Ligase IV-dependent pathway.

Cohen Z, Bacharach E, Lavi S.

Oncogene. 2006 Aug 3;25(33):4515-24. Epub 2006 Mar 20.


Single point mutations in the zinc finger motifs of the human immunodeficiency virus type 1 nucleocapsid alter RNA binding specificities of the gag protein and enhance packaging and infectivity.

Mark-Danieli M, Laham N, Kenan-Eichler M, Castiel A, Melamed D, Landau M, Bouvier NM, Evans MJ, Bacharach E.

J Virol. 2005 Jun;79(12):7756-67.


Selecton: a server for detecting evolutionary forces at a single amino-acid site.

Doron-Faigenboim A, Stern A, Mayrose I, Bacharach E, Pupko T.

Bioinformatics. 2005 May 1;21(9):2101-3. Epub 2005 Jan 12.


Tumor-microenvironment interactions: the fucose-generating FX enzyme controls adhesive properties of colorectal cancer cells.

Zipin A, Israeli-Amit M, Meshel T, Sagi-Assif O, Yron I, Lifshitz V, Bacharach E, Smorodinsky NI, Many A, Czernilofsky PA, Morton DL, Witz IP.

Cancer Res. 2004 Sep 15;64(18):6571-8. Erratum in: Cancer Res. 2004 Nov 1;64(21):8130.


The conserved carboxy terminus of the capsid domain of human immunodeficiency virus type 1 gag protein is important for virion assembly and release.

Melamed D, Mark-Danieli M, Kenan-Eichler M, Kraus O, Castiel A, Laham N, Pupko T, Glaser F, Ben-Tal N, Bacharach E.

J Virol. 2004 Sep;78(18):9675-88.


Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding.

Amit I, Yakir L, Katz M, Zwang Y, Marmor MD, Citri A, Shtiegman K, Alroy I, Tuvia S, Reiss Y, Roubini E, Cohen M, Wides R, Bacharach E, Schubert U, Yarden Y.

Genes Dev. 2004 Jul 15;18(14):1737-52.


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