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Items: 7


Advances and challenges in targeting FGFR signalling in cancer.

Babina IS, Turner NC.

Nat Rev Cancer. 2017 May;17(5):318-332. doi: 10.1038/nrc.2017.8. Epub 2017 Mar 17. Review.


Gatekeeper Mutations and Intratumoral Heterogeneity in FGFR2-Translocated Cholangiocarcinoma.

Smyth EC, Babina IS, Turner NC.

Cancer Discov. 2017 Mar;7(3):248-249. doi: 10.1158/2159-8290.CD-17-0057.


The Controlling Cancer Summit, 17-19 May 2016, London, UK.

Babina IS.

Future Oncol. 2016 Oct;12(20):2363-5. doi: 10.2217/fon-2016-0297. Epub 2016 Jul 25.


High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial.

Pearson A, Smyth E, Babina IS, Herrera-Abreu MT, Tarazona N, Peckitt C, Kilgour E, Smith NR, Geh C, Rooney C, Cutts R, Campbell J, Ning J, Fenwick K, Swain A, Brown G, Chua S, Thomas A, Johnston SRD, Ajaz M, Sumpter K, Gillbanks A, Watkins D, Chau I, Popat S, Cunningham D, Turner NC.

Cancer Discov. 2016 Aug;6(8):838-851. doi: 10.1158/2159-8290.CD-15-1246. Epub 2016 May 13.


A novel mechanism of regulating breast cancer cell migration via palmitoylation-dependent alterations in the lipid raft affiliation of CD44.

Babina IS, McSherry EA, Donatello S, Hill AD, Hopkins AM.

Breast Cancer Res. 2014 Feb 10;16(1):R19. doi: 10.1186/bcr3614.


Lipid raft association restricts CD44-ezrin interaction and promotion of breast cancer cell migration.

Donatello S, Babina IS, Hazelwood LD, Hill AD, Nabi IR, Hopkins AM.

Am J Pathol. 2012 Dec;181(6):2172-87. doi: 10.1016/j.ajpath.2012.08.025. Epub 2012 Sep 29.


Lipid rafts are disrupted in mildly inflamed intestinal microenvironments without overt disruption of the epithelial barrier.

Bowie RV, Donatello S, Lyes C, Owens MB, Babina IS, Hudson L, Walsh SV, O'Donoghue DP, Amu S, Barry SP, Fallon PG, Hopkins AM.

Am J Physiol Gastrointest Liver Physiol. 2012 Apr 15;302(8):G781-93. doi: 10.1152/ajpgi.00002.2011. Epub 2012 Jan 12.

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