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Items: 13

1.

Corrigendum to "Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling" [Bioorg. Med. Chem. 24 (2016) 2215-2234].

Liu L, Lee MR, Kim JL, Whittington DA, Bregman H, Hua Z, Lewis RT, Martin MW, Nishimura N, Potashman M, Yang K, Yi S, Vaida KR, Epstein LF, Babij C, Fernando M, Carnahan J, Norman MH.

Bioorg Med Chem. 2016 Jul 1;24(13):3093. doi: 10.1016/j.bmc.2016.05.014. Epub 2016 May 24. No abstract available.

PMID:
27234892
2.

Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling.

Liu L, Lee MR, Kim JL, Whittington DA, Bregman H, Hua Z, Lewis RT, Martin MW, Nishimura N, Potashman M, Yang K, Yi S, Vaida KR, Epstein LF, Babij C, Fernando M, Carnahan J, Norman MH.

Bioorg Med Chem. 2016 May 15;24(10):2215-34. doi: 10.1016/j.bmc.2016.03.055. Epub 2016 Apr 13. Erratum in: Bioorg Med Chem. 2016 Jul 1;24(13):3093.

PMID:
27085672
3.

STK33 kinase activity is nonessential in KRAS-dependent cancer cells.

Babij C, Zhang Y, Kurzeja RJ, Munzli A, Shehabeldin A, Fernando M, Quon K, Kassner PD, Ruefli-Brasse AA, Watson VJ, Fajardo F, Jackson A, Zondlo J, Sun Y, Ellison AR, Plewa CA, San MT, Robinson J, McCarter J, Schwandner R, Judd T, Carnahan J, Dussault I.

Cancer Res. 2011 Sep 1;71(17):5818-26. doi: 10.1158/0008-5472.CAN-11-0778. Epub 2011 Jul 8.

4.

Selective and potent Raf inhibitors paradoxically stimulate normal cell proliferation and tumor growth.

Carnahan J, Beltran PJ, Babij C, Le Q, Rose MJ, Vonderfecht S, Kim JL, Smith AL, Nagapudi K, Broome MA, Fernando M, Kha H, Belmontes B, Radinsky R, Kendall R, Burgess TL.

Mol Cancer Ther. 2010 Aug;9(8):2399-410. doi: 10.1158/1535-7163.MCT-10-0181. Epub 2010 Jul 27.

5.

Selective inhibitors of the mutant B-Raf pathway: discovery of a potent and orally bioavailable aminoisoquinoline.

Smith AL, DeMorin FF, Paras NA, Huang Q, Petkus JK, Doherty EM, Nixey T, Kim JL, Whittington DA, Epstein LF, Lee MR, Rose MJ, Babij C, Fernando M, Hess K, Le Q, Beltran P, Carnahan J.

J Med Chem. 2009 Oct 22;52(20):6189-92. doi: 10.1021/jm901081g.

PMID:
19764794
6.

Kinetic study of the reaction of [Rh(6)(CO)(16)] with NO(2)(-): insertion of the nitrogen atom into a Rh(6) cluster core.

Babij C, Farrar DH, Poë AJ, Tunik SP.

Dalton Trans. 2008 Nov 21;(43):5922-9. doi: 10.1039/b808666d. Epub 2008 Sep 15.

PMID:
19082048
7.

Kinetic studies of some substituted hexarhodium carbonyl clusters.

Babij C, Farrar DH, Koshevoy IO, Poë AJ, Tunik SP.

Dalton Trans. 2005 Jan 7;(1):116-22. Epub 2004 Nov 25.

PMID:
15605154
8.

QALE analysis of CO dissociative kinetics of Ru(CO)4L (L = P-donor ligands): accelerating effects of hydrogen in PHnR(3 - n) ligands (n = 1-2).

Babij C, Chen L, Koshevoy IO, Poë AJ.

Dalton Trans. 2004 Mar 7;(5):833-8. Epub 2004 Feb 10.

PMID:
15252507
9.

Tripyrrolylphosphine as a unique bridging ligand in the Rh6CO14(mu2-P(NC4H4)3) cluster: structure, bonding, fluxionality, thermodynamics, and kinetics studies.

Babij C, Browning CS, Farrar DH, Koshevoy IO, Podkorytov IS, Poë AJ, Tunik SP.

J Am Chem Soc. 2002 Jul 31;124(30):8922-31.

PMID:
12137547
10.

Rapamycin, but not FK506 and GPI-1046, increases neurite outgrowth in PC12 cells by inhibiting cell cycle progression.

Parker EM, Monopoli A, Ongini E, Lozza G, Babij CM.

Neuropharmacology. 2000 Jul 24;39(10):1913-9.

PMID:
10884572
11.

GR231118 (1229U91) and other analogues of the C-terminus of neuropeptide Y are potent neuropeptide Y Y1 receptor antagonists and neuropeptide Y Y4 receptor agonists.

Parker EM, Babij CK, Balasubramaniam A, Burrier RE, Guzzi M, Hamud F, Mukhopadhyay G, Rudinski MS, Tao Z, Tice M, Xia L, Mullins DE, Salisbury BG.

Eur J Pharmacol. 1998 May 15;349(1):97-105.

PMID:
9669502
12.

Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons.

Eilers A, Whitfield J, Babij C, Rubin LL, Ham J.

J Neurosci. 1998 Mar 1;18(5):1713-24.

13.

A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death.

Ham J, Babij C, Whitfield J, Pfarr CM, Lallemand D, Yaniv M, Rubin LL.

Neuron. 1995 May;14(5):927-39.

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