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Items: 8


αβ T-cell receptors from multiple sclerosis brain lesions show MAIT cell-related features.

Held K, Bhonsle-Deeng L, Siewert K, Sato W, Beltrán E, Schmidt S, Rühl G, Ng JK, Engerer P, Moser M, Klinkert WE, Babbe H, Misgeld T, Wekerle H, Laplaud DA, Hohlfeld R, Dornmair K.

Neurol Neuroimmunol Neuroinflamm. 2015 May 7;2(4):e107. doi: 10.1212/NXI.0000000000000107. eCollection 2015 Aug.


Genomic instability resulting from Blm deficiency compromises development, maintenance, and function of the B cell lineage.

Babbe H, McMenamin J, Hobeika E, Wang J, Rodig SJ, Reth M, Leder P.

J Immunol. 2009 Jan 1;182(1):347-60.


The Bloom's syndrome helicase is critical for development and function of the alphabeta T-cell lineage.

Babbe H, Chester N, Leder P, Reizis B.

Mol Cell Biol. 2007 Mar;27(5):1947-59. Epub 2007 Jan 8.


Mutation of the murine Bloom's syndrome gene produces global genome destabilization.

Chester N, Babbe H, Pinkas J, Manning C, Leder P.

Mol Cell Biol. 2006 Sep;26(17):6713-26.


A bifunctional targeted peptide that blocks HER-2 tyrosine kinase and disables mitochondrial function in HER-2-positive carcinoma cells.

Fantin VR, Berardi MJ, Babbe H, Michelman MV, Manning CM, Leder P.

Cancer Res. 2005 Aug 1;65(15):6891-900.


Multiple sclerosis: brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and blood.

Skulina C, Schmidt S, Dornmair K, Babbe H, Roers A, Rajewsky K, Wekerle H, Hohlfeld R, Goebels N.

Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2428-33.


Clonal tracking of autoaggressive T cells in polymyositis by combining laser microdissection, single-cell PCR, and CDR3-spectratype analysis.

Hofbauer M, Wiesener S, Babbe H, Roers A, Wekerle H, Dornmair K, Hohlfeld R, Goebels N.

Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4090-5. Epub 2003 Mar 21.


Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction.

Babbe H, Roers A, Waisman A, Lassmann H, Goebels N, Hohlfeld R, Friese M, Schröder R, Deckert M, Schmidt S, Ravid R, Rajewsky K.

J Exp Med. 2000 Aug 7;192(3):393-404.

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