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Items: 1 to 50 of 51

1.

Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism.

Valli A, Morotti M, Zois CE, Albers PK, Soga T, Feldinger K, Fischer R, Frejno M, McIntyre A, Bridges E, Haider S, Buffa FM, Baban D, Rodriguez M, Yanes O, Whittington HJ, Lake HA, Zervou S, Lygate CA, Kessler BM, Harris AL.

Mol Cancer Res. 2019 Jul;17(7):1531-1544. doi: 10.1158/1541-7786.MCR-18-0315. Epub 2019 Mar 18.

PMID:
30885992
2.

Mammalian γ2 AMPK regulates intrinsic heart rate.

Yavari A, Bellahcene M, Bucchi A, Sirenko S, Pinter K, Herring N, Jung JJ, Tarasov KV, Sharpe EJ, Wolfien M, Czibik G, Steeples V, Ghaffari S, Nguyen C, Stockenhuber A, Clair JRS, Rimmbach C, Okamoto Y, Yang D, Wang M, Ziman BD, Moen JM, Riordon DR, Ramirez C, Paina M, Lee J, Zhang J, Ahmet I, Matt MG, Tarasova YS, Baban D, Sahgal N, Lockstone H, Puliyadi R, de Bono J, Siggs OM, Gomes J, Muskett H, Maguire ML, Beglov Y, Kelly M, Dos Santos PPN, Bright NJ, Woods A, Gehmlich K, Isackson H, Douglas G, Ferguson DJP, Schneider JE, Tinker A, Wolkenhauer O, Channon KM, Cornall RJ, Sternick EB, Paterson DJ, Redwood CS, Carling D, Proenza C, David R, Baruscotti M, DiFrancesco D, Lakatta EG, Watkins H, Ashrafian H.

Nat Commun. 2017 Nov 2;8(1):1258. doi: 10.1038/s41467-017-01342-5.

3.

Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory protein.

Buschow SI, Ramazzotti M, Reinieren-Beeren IMJ, Heinzerling LM, Westdorp H, Stefanini I, Beltrame L, Hato SV, Ellebaek E, Gross S, Nguyen VA, Weinlich G, Ragoussis J, Baban D, Schuler-Thurner B, Svane IM, Romani N, Austyn JM, De Vries IJM, Schuler G, Cavalieri D, Figdor CG.

Oncotarget. 2017 Jun 27;8(40):67439-67456. doi: 10.18632/oncotarget.18698. eCollection 2017 Sep 15.

4.

Impact of IL-27 on hepatocyte antiviral gene expression and function.

Ramamurthy N, Boninsegna S, Adams R, Sahgal N, Lockstone H, Baban D, Marchi E, Klenerman P.

Wellcome Open Res. 2016 Nov 17;1:17. doi: 10.12688/wellcomeopenres.9917.1.

5.

The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer.

da Motta LL, Ledaki I, Purshouse K, Haider S, De Bastiani MA, Baban D, Morotti M, Steers G, Wigfield S, Bridges E, Li JL, Knapp S, Ebner D, Klamt F, Harris AL, McIntyre A.

Oncogene. 2017 Jan 5;36(1):122-132. doi: 10.1038/onc.2016.184. Epub 2016 Jun 13.

6.

Estrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer.

Yang J, AlTahan A, Jones DT, Buffa FM, Bridges E, Interiano RB, Qu C, Vogt N, Li JL, Baban D, Ragoussis J, Nicholson R, Davidoff AM, Harris AL.

Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15172-7. doi: 10.1073/pnas.1422015112. Epub 2015 Nov 23.

7.

Adenoviral Vector Vaccination Induces a Conserved Program of CD8(+) T Cell Memory Differentiation in Mouse and Man.

Bolinger B, Sims S, Swadling L, O'Hara G, de Lara C, Baban D, Saghal N, Lee LN, Marchi E, Davis M, Newell E, Capone S, Folgori A, Barnes E, Klenerman P.

Cell Rep. 2015 Nov 24;13(8):1578-88. doi: 10.1016/j.celrep.2015.10.034. Epub 2015 Nov 12.

8.

Pattern recognition receptor mediated downregulation of microRNA-650 fine-tunes MxA expression in dendritic cells infected with influenza A virus.

Pichulik T, Khatamzas E, Liu X, Brain O, Delmiro Garcia M, Leslie A, Danis B, Mayer A, Baban D, Ragoussis J, Weber AN, Simmons A.

Eur J Immunol. 2016 Jan;46(1):167-77. doi: 10.1002/eji.201444970. Epub 2015 Oct 30.

9.

Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition.

Ledaki I, McIntyre A, Wigfield S, Buffa F, McGowan S, Baban D, Li JL, Harris AL.

Oncotarget. 2015 Aug 14;6(23):19413-27.

10.

Microarray-based optimization to detect genomic deletion mutations.

Belfield EJ, Brown C, Gan X, Jiang C, Baban D, Mithani A, Mott R, Ragoussis J, Harberd NP.

Genom Data. 2014 Dec;2:53-54.

11.

CD161 defines a transcriptional and functional phenotype across distinct human T cell lineages.

Fergusson JR, Smith KE, Fleming VM, Rajoriya N, Newell EW, Simmons R, Marchi E, Björkander S, Kang YH, Swadling L, Kurioka A, Sahgal N, Lockstone H, Baban D, Freeman GJ, Sverremark-Ekström E, Davis MM, Davenport MP, Venturi V, Ussher JE, Willberg CB, Klenerman P.

Cell Rep. 2014 Nov 6;9(3):1075-88. doi: 10.1016/j.celrep.2014.09.045. Epub 2014 Oct 23.

12.

Microarray-based ultra-high resolution discovery of genomic deletion mutations.

Belfield EJ, Brown C, Gan X, Jiang C, Baban D, Mithani A, Mott R, Ragoussis J, Harberd NP.

BMC Genomics. 2014 Mar 22;15:224. doi: 10.1186/1471-2164-15-224.

13.

Nlrp3 activation in the intestinal epithelium protects against a mucosal pathogen.

Song-Zhao GX, Srinivasan N, Pott J, Baban D, Frankel G, Maloy KJ.

Mucosal Immunol. 2014 Jul;7(4):763-774. doi: 10.1038/mi.2013.94. Epub 2013 Nov 27.

14.

A chronological expression profile of gene activity during embryonic mouse brain development.

Goggolidou P, Soneji S, Powles-Glover N, Williams D, Sethi S, Baban D, Simon MM, Ragoussis I, Norris DP.

Mamm Genome. 2013 Dec;24(11-12):459-72. doi: 10.1007/s00335-013-9486-7. Epub 2013 Nov 19.

15.

A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia.

Adam J, Yang M, Bauerschmidt C, Kitagawa M, O'Flaherty L, Maheswaran P, Özkan G, Sahgal N, Baban D, Kato K, Saito K, Iino K, Igarashi K, Stratford M, Pugh C, Tennant DA, Ludwig C, Davies B, Ratcliffe PJ, El-Bahrawy M, Ashrafian H, Soga T, Pollard PJ.

Cell Rep. 2013 May 30;3(5):1440-8. doi: 10.1016/j.celrep.2013.04.006. Epub 2013 May 2.

16.

Smooth muscle cells differentiated from reprogrammed embryonic lung fibroblasts through DKK3 signaling are potent for tissue engineering of vascular grafts.

Karamariti E, Margariti A, Winkler B, Wang X, Hong X, Baban D, Ragoussis J, Huang Y, Han JD, Wong MM, Sag CM, Shah AM, Hu Y, Xu Q.

Circ Res. 2013 May 24;112(11):1433-43. doi: 10.1161/CIRCRESAHA.111.300415. Epub 2013 Mar 25.

PMID:
23529184
17.

Direct reprogramming of fibroblasts into endothelial cells capable of angiogenesis and reendothelialization in tissue-engineered vessels.

Margariti A, Winkler B, Karamariti E, Zampetaki A, Tsai TN, Baban D, Ragoussis J, Huang Y, Han JD, Zeng L, Hu Y, Xu Q.

Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13793-8. doi: 10.1073/pnas.1205526109. Epub 2012 Aug 6.

18.

Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation.

Nicolaidou V, Wong MM, Redpath AN, Ersek A, Baban DF, Williams LM, Cope AP, Horwood NJ.

PLoS One. 2012;7(7):e39871. doi: 10.1371/journal.pone.0039871. Epub 2012 Jul 3.

19.

Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling.

Adam J, Hatipoglu E, O'Flaherty L, Ternette N, Sahgal N, Lockstone H, Baban D, Nye E, Stamp GW, Wolhuter K, Stevens M, Fischer R, Carmeliet P, Maxwell PH, Pugh CW, Frizzell N, Soga T, Kessler BM, El-Bahrawy M, Ratcliffe PJ, Pollard PJ.

Cancer Cell. 2011 Oct 18;20(4):524-37. doi: 10.1016/j.ccr.2011.09.006.

20.

Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain.

Vernes SC, Oliver PL, Spiteri E, Lockstone HE, Puliyadi R, Taylor JM, Ho J, Mombereau C, Brewer A, Lowy E, Nicod J, Groszer M, Baban D, Sahgal N, Cazier JB, Ragoussis J, Davies KE, Geschwind DH, Fisher SE.

PLoS Genet. 2011 Jul;7(7):e1002145. doi: 10.1371/journal.pgen.1002145. Epub 2011 Jul 7.

21.

Substantial histone reduction modulates genomewide nucleosomal occupancy and global transcriptional output.

Celona B, Weiner A, Di Felice F, Mancuso FM, Cesarini E, Rossi RL, Gregory L, Baban D, Rossetti G, Grianti P, Pagani M, Bonaldi T, Ragoussis J, Friedman N, Camilloni G, Bianchi ME, Agresti A.

PLoS Biol. 2011 Jun;9(6):e1001086. doi: 10.1371/journal.pbio.1001086. Epub 2011 Jun 28.

22.

MicroRNA controlled adenovirus mediates anti-cancer efficacy without affecting endogenous microRNA activity.

Cawood R, Wong SL, Di Y, Baban DF, Seymour LW.

PLoS One. 2011 Jan 10;6(1):e16152. doi: 10.1371/journal.pone.0016152.

23.

Chemokine gene expression in lung CD8 T cells correlates with protective immunity in mice immunized intra-nasally with Adenovirus-85A.

Lee LN, Baban D, Ronan EO, Ragoussis J, Beverley PC, Tchilian EZ.

BMC Med Genomics. 2010 Oct 13;3:46. doi: 10.1186/1755-8794-3-46.

24.

The histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia, and is a key mediator of estrogen induced growth.

Yang J, Jubb AM, Pike L, Buffa FM, Turley H, Baban D, Leek R, Gatter KC, Ragoussis J, Harris AL.

Cancer Res. 2010 Aug 15;70(16):6456-66. doi: 10.1158/0008-5472.CAN-10-0413. Epub 2010 Aug 3.

25.

Gene set analysis of lung samples provides insight into pathogenesis of progressive, fibrotic pulmonary sarcoidosis.

Lockstone HE, Sanderson S, Kulakova N, Baban D, Leonard A, Kok WL, McGowan S, McMichael AJ, Ho LP.

Am J Respir Crit Care Med. 2010 Jun 15;181(12):1367-75. doi: 10.1164/rccm.200912-1855OC. Epub 2010 Mar 1.

PMID:
20194811
26.

CpG methylation profiling in VHL related and VHL unrelated renal cell carcinoma.

McRonald FE, Morris MR, Gentle D, Winchester L, Baban D, Ragoussis J, Clarke NW, Brown MD, Kishida T, Yao M, Latif F, Maher ER.

Mol Cancer. 2009 Jun 3;8:31. doi: 10.1186/1476-4598-8-31.

27.

Human CD4+ memory T cells are preferential targets for bystander activation and apoptosis.

Bangs SC, Baban D, Cattan HJ, Li CK, McMichael AJ, Xu XN.

J Immunol. 2009 Feb 15;182(4):1962-71. doi: 10.4049/jimmunol.0802596.

28.

Effects of FSH on testicular mRNA transcript levels in the hypogonadal mouse.

Abel MH, Baban D, Lee S, Charlton HM, O'Shaughnessy PJ.

J Mol Endocrinol. 2009 Apr;42(4):291-303. doi: 10.1677/JME-08-0107. Epub 2009 Jan 9.

29.

A novel gene expression profile in lymphatics associated with tumor growth and nodal metastasis.

Clasper S, Royston D, Baban D, Cao Y, Ewers S, Butz S, Vestweber D, Jackson DG.

Cancer Res. 2008 Sep 15;68(18):7293-303. doi: 10.1158/0008-5472.CAN-07-6506.

30.

Gpr83 expression is not required for the maintenance of intestinal immune homeostasis and regulation of T-cell-dependent colitis.

Toms C, Jessup H, Thompson C, Baban D, Davies K, Powrie F.

Immunology. 2008 Nov;125(3):302-12. doi: 10.1111/j.1365-2567.2008.02857.x. Epub 2008 May 9.

31.

Microarray analysis of mdx mice expressing high levels of utrophin: therapeutic implications for dystrophin deficiency.

Baban D, Davies KE.

Neuromuscul Disord. 2008 Mar;18(3):239-47. doi: 10.1016/j.nmd.2007.11.011. Epub 2008 Mar 14.

PMID:
18343112
32.

Genome-wide expression analysis of a spinal muscular atrophy model: towards discovery of new drug targets.

Lee S, Sayin A, Cauchi RJ, Grice S, Burdett H, Baban D, van den Heuvel M.

PLoS One. 2008 Jan 2;3(1):e1404. doi: 10.1371/journal.pone.0001404. Erratum in: PLoS ONE. 2008;3(4). doi: 10.1371/annotation/f45a5dc0-e317-4886-8c5b-1569c79a5f08. Cauchi, Ruben J [added].

33.

Utrophin up-regulation by an artificial transcription factor in transgenic mice.

Mattei E, Corbi N, Di Certo MG, Strimpakos G, Severini C, Onori A, Desantis A, Libri V, Buontempo S, Floridi A, Fanciulli M, Baban D, Davies KE, Passananti C.

PLoS One. 2007 Aug 22;2(8):e774.

34.

Cox-2 promotes chromogranin A expression and bioactivity: evidence for a prostaglandin E2-dependent mechanism and the involvement of a proximal cyclic adenosine 5'-monophosphate-responsive element.

Connolly R, Gates D, Loh N, Baban D, Thakker R, Johnston B, McCance D, Ardill J, O'Connor DT, Taupenot L, McGinty A.

Endocrinology. 2007 Sep;148(9):4310-7. Epub 2007 May 31.

PMID:
17540723
35.

Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication.

Hodges A, Sharrocks K, Edelmann M, Baban D, Moris A, Schwartz O, Drakesmith H, Davies K, Kessler B, McMichael A, Simmons A.

Nat Immunol. 2007 Jun;8(6):569-77. Epub 2007 May 13.

PMID:
17496896
36.

Transcriptional profiling of human cord blood CD133+ and cultured bone marrow mesenchymal stem cells in response to hypoxia.

Martin-Rendon E, Hale SJ, Ryan D, Baban D, Forde SP, Roubelakis M, Sweeney D, Moukayed M, Harris AL, Davies K, Watt SM.

Stem Cells. 2007 Apr;25(4):1003-12. Epub 2006 Dec 21.

37.

An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium.

Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG.

J Exp Med. 2006 Nov 27;203(12):2763-77. Epub 2006 Nov 20.

38.

Gene expression profiling studies on Caenorhabditis elegans dystrophin mutants dys-1(cx-35) and dys-1(cx18).

Towers PR, Lescure P, Baban D, Malek JA, Duarte J, Jones E, Davies KE, Ségalat L, Sattelle DB.

Genomics. 2006 Nov;88(5):642-9. Epub 2006 Sep 7.

39.

Genomic clusters, putative pathogen recognition molecules, and antimicrobial genes are induced by infection of C. elegans with M. nematophilum.

O'Rourke D, Baban D, Demidova M, Mott R, Hodgkin J.

Genome Res. 2006 Aug;16(8):1005-16. Epub 2006 Jun 29.

40.

Expression profiling in spinal muscular atrophy reveals an RNA binding protein deficit.

Anderson KN, Baban D, Oliver PL, Potter A, Davies KE.

Neuromuscul Disord. 2004 Nov;14(11):711-22.

PMID:
15482955
41.

Protein expression changes in spinal muscular atrophy revealed with a novel antibody array technology.

Anderson K, Potter A, Baban D, Davies KE.

Brain. 2003 Sep;126(Pt 9):2052-64. Epub 2003 Jul 7.

PMID:
12847076
42.

Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery.

Mazarakis ND, Azzouz M, Rohll JB, Ellard FM, Wilkes FJ, Olsen AL, Carter EE, Barber RD, Baban DF, Kingsman SM, Kingsman AJ, O'Malley K, Mitrophanous KA.

Hum Mol Genet. 2001 Sep 15;10(19):2109-21.

PMID:
11590128
43.

Direct retroviral delivery of human cytochrome P450 2B6 for gene-directed enzyme prodrug therapy of cancer.

Kan O, Griffiths L, Baban D, Iqball S, Uden M, Spearman H, Slingsby J, Price T, Esapa M, Kingsman S, Kingsman A, Slade A, Naylor S.

Cancer Gene Ther. 2001 Jul;8(7):473-82.

44.

Analysis of 4070A envelope levels in retroviral preparations and effect on target cell transduction efficiency.

Slingsby JH, Baban D, Sutton J, Esapa M, Price T, Kingsman SM, Kingsman AJ, Slade A.

Hum Gene Ther. 2000 Jul 1;11(10):1439-51.

PMID:
10910141
45.

Control of tumour vascular permeability.

Baban DF, Seymour LW.

Adv Drug Deliv Rev. 1998 Oct 5;34(1):109-119.

PMID:
10837673
46.

Quantitative analysis of vascular endothelial growth factor expression in chronic lymphocytic leukaemia.

Baban D, Murray J, Earl H, Kerr D, Seymour L.

Int J Oncol. 1996 Jan;8(1):29-34.

PMID:
21544327
47.

Melanoma cell lines express VEGF receptor KDR and respond to exogenously added VEGF.

Liu B, Earl HM, Baban D, Shoaibi M, Fabra A, Kerr DJ, Seymour LW.

Biochem Biophys Res Commun. 1995 Dec 26;217(3):721-7.

PMID:
8554590
48.

Effects of inoculation site and Matrigel on growth and metastasis of human breast cancer cells.

Bao L, Matsumura Y, Baban D, Sun Y, Tarin D.

Br J Cancer. 1994 Aug;70(2):228-32.

49.
50.

Correlation of VLA-4 integrin expression with metastatic potential in various human tumour cell lines.

Bao L, Pigott R, Matsumura Y, Baban D, Tarin D.

Differentiation. 1993 Mar;52(3):239-46.

PMID:
7683291

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