Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 70


Meiotic arrest occurs most frequently at metaphase and is often incomplete in azoospermic men.

Enguita-Marruedo A, Sleddens-Linkels E, Ooms M, de Geus V, Wilke M, Blom E, Dohle GR, Looijenga LHJ, van Cappellen W, Baart EB, Baarends WM.

Fertil Steril. 2019 Nov 22. pii: S0015-0282(19)31992-2. doi: 10.1016/j.fertnstert.2019.08.004. [Epub ahead of print]


HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis.

Brandsma I, Sato K, van Rossum-Fikkert SE, van Vliet N, Sleddens E, Reuter M, Odijk H, van den Tempel N, Dekkers DHW, Bezstarosti K, Demmers JAA, Maas A, Lebbink J, Wyman C, Essers J, van Gent DC, Baarends WM, Knipscheer P, Kanaar R, Zelensky AN.

Cell Rep. 2019 Jun 25;27(13):3790-3798.e7. doi: 10.1016/j.celrep.2019.05.096.


Sequencing of a 'mouse azoospermia' gene panel in azoospermic men: identification of RNF212 and STAG3 mutations as novel genetic causes of meiotic arrest.

Riera-Escamilla A, Enguita-Marruedo A, Moreno-Mendoza D, Chianese C, Sleddens-Linkels E, Contini E, Benelli M, Natali A, Colpi GM, Ruiz-Castañé E, Maggi M, Baarends WM, Krausz C.

Hum Reprod. 2019 Jun 4;34(6):978-988. doi: 10.1093/humrep/dez042.


A novel approach to differentiate rat embryonic stem cells in vitro reveals a role for RNF12 in activation of X chromosome inactivation.

Magaraki A, Loda A, Gontan C, Merzouk S, Sleddens-Linkels E, Meek S, Baarends WM, Burdon T, Gribnau J.

Sci Rep. 2019 Apr 15;9(1):6068. doi: 10.1038/s41598-019-42246-2.


SMoLR: visualization and analysis of single-molecule localization microscopy data in R.

Paul MW, de Gruiter HM, Lin Z, Baarends WM, van Cappellen WA, Houtsmuller AB, Slotman JA.

BMC Bioinformatics. 2019 Jan 15;20(1):30. doi: 10.1186/s12859-018-2578-3.


Simultaneous RNA-DNA FISH in Mouse Preimplantation Embryos.

Magaraki A, Loda A, Gribnau J, Baarends WM.

Methods Mol Biol. 2018;1861:131-147. doi: 10.1007/978-1-4939-8766-5_11.


Live cell analyses of synaptonemal complex dynamics and chromosome movements in cultured mouse testis tubules and embryonic ovaries.

Enguita-Marruedo A, Van Cappellen WA, Hoogerbrugge JW, Carofiglio F, Wassenaar E, Slotman JA, Houtsmuller A, Baarends WM.

Chromosoma. 2018 Sep;127(3):341-359. doi: 10.1007/s00412-018-0668-7. Epub 2018 Mar 26.


Repair of exogenous DNA double-strand breaks promotes chromosome synapsis in SPO11-mutant mouse meiocytes, and is altered in the absence of HORMAD1.

Carofiglio F, Sleddens-Linkels E, Wassenaar E, Inagaki A, van Cappellen WA, Grootegoed JA, Toth A, Baarends WM.

DNA Repair (Amst). 2018 Mar;63:25-38. doi: 10.1016/j.dnarep.2018.01.007. Epub 2018 Jan 31.


Silencing markers are retained on pericentric heterochromatin during murine primordial germ cell development.

Magaraki A, van der Heijden G, Sleddens-Linkels E, Magarakis L, van Cappellen WA, Peters AHFM, Gribnau J, Baarends WM, Eijpe M.

Epigenetics Chromatin. 2017 Mar 11;10:11. doi: 10.1186/s13072-017-0119-3. eCollection 2017.


Round Spermatid Injection Rescues Female Lethality of a Paternally Inherited Xist Deletion in Mouse.

Federici F, Magaraki A, Wassenaar E, van Veen-Buurman CJ, van de Werken C, Baart EB, Laven JS, Grootegoed JA, Gribnau J, Baarends WM.

PLoS Genet. 2016 Oct 7;12(10):e1006358. doi: 10.1371/journal.pgen.1006358. eCollection 2016 Oct.


Genomes of Ellobius species provide insight into the evolutionary dynamics of mammalian sex chromosomes.

Mulugeta E, Wassenaar E, Sleddens-Linkels E, van IJcken WF, Heard E, Grootegoed JA, Just W, Gribnau J, Baarends WM.

Genome Res. 2016 Sep;26(9):1202-10. doi: 10.1101/gr.201665.115. Epub 2016 Aug 10.


An essential role for UBE2A/HR6A in learning and memory and mGLUR-dependent long-term depression.

Bruinsma CF, Savelberg SM, Kool MJ, Jolfaei MA, Van Woerden GM, Baarends WM, Elgersma Y.

Hum Mol Genet. 2016 Jan 1;25(1):1-8. doi: 10.1093/hmg/ddv436. Epub 2015 Oct 16.


Incomplete meiotic sex chromosome inactivation in the domestic dog.

Federici F, Mulugeta E, Schoenmakers S, Wassenaar E, Hoogerbrugge JW, van der Heijden GW, van Cappellen WA, Slotman JA, van IJcken WF, Laven JS, Grootegoed JA, Baarends WM.

BMC Genomics. 2015 Apr 12;16:291. doi: 10.1186/s12864-015-1501-9.


Paternal heterochromatin formation in human embryos is H3K9/HP1 directed and primed by sperm-derived histone modifications.

van de Werken C, van der Heijden GW, Eleveld C, Teeuwssen M, Albert M, Baarends WM, Laven JS, Peters AH, Baart EB.

Nat Commun. 2014 Dec 18;5:5868. doi: 10.1038/ncomms6868.


A mRad51-GFP antimorphic allele affects homologous recombination and DNA damage sensitivity.

Uringa EJ, Baldeyron C, Odijk H, Wassenaar E, van Cappellen WA, Maas A, Hoeijmakers JH, Baarends WM, Kanaar R, Essers J.

DNA Repair (Amst). 2015 Jan;25:27-40. doi: 10.1016/j.dnarep.2014.11.002. Epub 2014 Nov 18.


Differential expression and sex chromosome association of CHD3/4 and CHD5 during spermatogenesis.

Bergs JW, Neuendorff N, van der Heijden G, Wassenaar E, Rexin P, Elsässer HP, Moll R, Baarends WM, Brehm A.

PLoS One. 2014 May 21;9(5):e98203. doi: 10.1371/journal.pone.0098203. eCollection 2014.


Chromatin dynamics during spermiogenesis.

Rathke C, Baarends WM, Awe S, Renkawitz-Pohl R.

Biochim Biophys Acta. 2014 Mar;1839(3):155-68. doi: 10.1016/j.bbagrm.2013.08.004. Epub 2013 Sep 30. Review.


SPO11-independent DNA repair foci and their role in meiotic silencing.

Carofiglio F, Inagaki A, de Vries S, Wassenaar E, Schoenmakers S, Vermeulen C, van Cappellen WA, Sleddens-Linkels E, Grootegoed JA, Te Riele HP, de Massy B, Baarends WM.

PLoS Genet. 2013 Jun;9(6):e1003538. doi: 10.1371/journal.pgen.1003538. Epub 2013 Jun 6.


Evolution of testis-specific kinases TSSK1B and TSSK2 in primates.

Shang P, Hoogerbrugge J, Baarends WM, Grootegoed JA.

Andrology. 2013 Jan;1(1):160-8. doi: 10.1111/j.2047-2927.2012.00021.x. Epub 2012 Oct 23.


Human RAD18 interacts with ubiquitylated chromatin components and facilitates RAD9 recruitment to DNA double strand breaks.

Inagaki A, Sleddens-Linkels E, van Cappellen WA, Hibbert RG, Sixma TK, Hoeijmakers JH, Grootegoed JA, Baarends WM.

PLoS One. 2011;6(8):e23155. doi: 10.1371/journal.pone.0023155. Epub 2011 Aug 17.


Meiotic functions of RAD18.

Inagaki A, Sleddens-Linkels E, Wassenaar E, Ooms M, van Cappellen WA, Hoeijmakers JH, Seibler J, Vogt TF, Shin MK, Grootegoed JA, Baarends WM.

J Cell Sci. 2011 Aug 15;124(Pt 16):2837-50. doi: 10.1242/jcs.081968.


The X and Y chromosome in meiosis: how and why they keep silent.

van der Heijden GW, Eijpe M, Baarends WM.

Asian J Androl. 2011 Nov;13(6):779-80. doi: 10.1038/aja.2011.93. Epub 2011 Jul 25. No abstract available.


Evaluating the relationship between spermatogenic silencing of the X chromosome and evolution of the Y chromosome in chimpanzee and human.

Mulugeta Achame E, Baarends WM, Gribnau J, Grootegoed JA.

PLoS One. 2010 Dec 14;5(12):e15598. doi: 10.1371/journal.pone.0015598.


The ubiquitin-conjugating enzyme HR6B is required for maintenance of X chromosome silencing in mouse spermatocytes and spermatids.

Mulugeta Achame E, Wassenaar E, Hoogerbrugge JW, Sleddens-Linkels E, Ooms M, Sun ZW, van IJcken WF, Grootegoed JA, Baarends WM.

BMC Genomics. 2010 Jun 10;11:367. doi: 10.1186/1471-2164-11-367.


DNA double strand break repair, chromosome synapsis and transcriptional silencing in meiosis.

Inagaki A, Schoenmakers S, Baarends WM.

Epigenetics. 2010 May 16;5(4):255-66. Epub 2010 May 16. Review.


Meiotic silencing and fragmentation of the male germline restricted chromosome in zebra finch.

Schoenmakers S, Wassenaar E, Laven JS, Grootegoed JA, Baarends WM.

Chromosoma. 2010 Jun;119(3):311-24. doi: 10.1007/s00412-010-0258-9. Epub 2010 Feb 17.


Sisters dancing in meiosis.

Baarends WM, Mercier R.

EMBO Rep. 2010 Feb;11(2):76-8. doi: 10.1038/embor.2009.277. Epub 2010 Jan 8. No abstract available.


Functional transformation of the chromatoid body in mouse spermatids requires testis-specific serine/threonine kinases.

Shang P, Baarends WM, Hoogerbrugge J, Ooms MP, van Cappellen WA, de Jong AA, Dohle GR, van Eenennaam H, Gossen JA, Grootegoed JA.

J Cell Sci. 2010 Feb 1;123(Pt 3):331-9. doi: 10.1242/jcs.059949. Epub 2010 Jan 5.


Female meiotic sex chromosome inactivation in chicken.

Schoenmakers S, Wassenaar E, Hoogerbrugge JW, Laven JS, Grootegoed JA, Baarends WM.

PLoS Genet. 2009 May;5(5):e1000466. doi: 10.1371/journal.pgen.1000466. Epub 2009 May 22.


Dynamic localization of human RAD18 during the cell cycle and a functional connection with DNA double-strand break repair.

Inagaki A, van Cappellen WA, van der Laan R, Houtsmuller AB, Hoeijmakers JH, Grootegoed JA, Baarends WM.

DNA Repair (Amst). 2009 Feb 1;8(2):190-201. doi: 10.1016/j.dnarep.2008.10.008. Epub 2008 Dec 2.


Increased frequency of asynapsis and associated meiotic silencing of heterologous chromatin in the presence of irradiation-induced extra DNA double strand breaks.

Schoenmakers S, Wassenaar E, van Cappellen WA, Derijck AA, de Boer P, Laven JS, Grootegoed JA, Baarends WM.

Dev Biol. 2008 May 1;317(1):270-81. doi: 10.1016/j.ydbio.2008.02.027. Epub 2008 Mar 4.


Increased phosphorylation and dimethylation of XY body histones in the Hr6b-knockout mouse is associated with derepression of the X chromosome.

Baarends WM, Wassenaar E, Hoogerbrugge JW, Schoenmakers S, Sun ZW, Grootegoed JA.

J Cell Sci. 2007 Jun 1;120(Pt 11):1841-51. Epub 2007 May 8.


Transition from a nucleosome-based to a protamine-based chromatin configuration during spermiogenesis in Drosophila.

Rathke C, Baarends WM, Jayaramaiah-Raja S, Bartkuhn M, Renkawitz R, Renkawitz-Pohl R.

J Cell Sci. 2007 May 1;120(Pt 9):1689-700.


Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stages.

Liebe B, Petukhova G, Barchi M, Bellani M, Braselmann H, Nakano T, Pandita TK, Jasin M, Fornace A, Meistrich ML, Baarends WM, Schimenti J, de Lange T, Keeney S, Camerini-Otero RD, Scherthan H.

Exp Cell Res. 2006 Nov 15;312(19):3768-81. Epub 2006 Aug 2.


Differential contributions of mammalian Rad54 paralogs to recombination, DNA damage repair, and meiosis.

Wesoly J, Agarwal S, Sigurdsson S, Bussen W, Van Komen S, Qin J, van Steeg H, van Benthem J, Wassenaar E, Baarends WM, Ghazvini M, Tafel AA, Heath H, Galjart N, Essers J, Grootegoed JA, Arnheim N, Bezzubova O, Buerstedde JM, Sung P, Kanaar R.

Mol Cell Biol. 2006 Feb;26(3):976-89.


Mouse Sycp1 functions in synaptonemal complex assembly, meiotic recombination, and XY body formation.

de Vries FA, de Boer E, van den Bosch M, Baarends WM, Ooms M, Yuan L, Liu JG, van Zeeland AA, Heyting C, Pastink A.

Genes Dev. 2005 Jun 1;19(11):1376-89.


Expression and possible functions of DNA lesion bypass proteins in spermatogenesis.

Laan R, Baarends WM, Wassenaar E, Roest HP, Hoeijmakers JH, Grootegoed JA.

Int J Androl. 2005 Feb;28(1):1-15. Review.


Silencing of unpaired chromatin and histone H2A ubiquitination in mammalian meiosis.

Baarends WM, Wassenaar E, van der Laan R, Hoogerbrugge J, Sleddens-Linkels E, Hoeijmakers JH, de Boer P, Grootegoed JA.

Mol Cell Biol. 2005 Feb;25(3):1041-53.


Basic helix-loop-helix transcription factor Tcfl5 interacts with the Calmegin gene promoter in mouse spermatogenesis.

Siep M, Sleddens-Linkels E, Mulders S, van Eenennaam H, Wassenaar E, Van Cappellen WA, Hoogerbrugge J, Grootegoed JA, Baarends WM.

Nucleic Acids Res. 2004 Dec 7;32(21):6425-36. Print 2004.


Ubiquitin ligase Rad18Sc localizes to the XY body and to other chromosomal regions that are unpaired and transcriptionally silenced during male meiotic prophase.

van der Laan R, Uringa EJ, Wassenaar E, Hoogerbrugge JW, Sleddens E, Odijk H, Roest HP, de Boer P, Hoeijmakers JH, Grootegoed JA, Baarends WM.

J Cell Sci. 2004 Oct 1;117(Pt 21):5023-33. Epub 2004 Sep 21.


The ubiquitin-conjugating DNA repair enzyme HR6A is a maternal factor essential for early embryonic development in mice.

Roest HP, Baarends WM, de Wit J, van Klaveren JW, Wassenaar E, Hoogerbrugge JW, van Cappellen WA, Hoeijmakers JH, Grootegoed JA.

Mol Cell Biol. 2004 Jun;24(12):5485-95.


Chromatin dynamics in the male meiotic prophase.

Baarends WM, Grootegoed JA.

Cytogenet Genome Res. 2003;103(3-4):225-34. Review.


Loss of HR6B ubiquitin-conjugating activity results in damaged synaptonemal complex structure and increased crossing-over frequency during the male meiotic prophase.

Baarends WM, Wassenaar E, Hoogerbrugge JW, van Cappellen G, Roest HP, Vreeburg J, Ooms M, Hoeijmakers JH, Grootegoed JA.

Mol Cell Biol. 2003 Feb;23(4):1151-62.


A double RING-H2 domain in RNF32, a gene expressed during sperm formation.

van Baren MJ, van der Linde HC, Breedveld GJ, Baarends WM, Rizzu P, de Graaff E, Oostra BA, Heutink P.

Biochem Biophys Res Commun. 2002 Mar 22;292(1):58-65.


DNA repair mechanisms and gametogenesis.

Baarends WM, van der Laan R, Grootegoed JA.

Reproduction. 2001 Jan;121(1):31-9. Review.


Molecular and cellular mechanisms in spermatogenesis.

Grootegoed JA, Siep M, Baarends WM.

Baillieres Best Pract Res Clin Endocrinol Metab. 2000 Sep;14(3):331-43. Review.


Specific aspects of the ubiquitin system in spermatogenesis.

Baarends WM, van der Laan R, Grootegoed JA.

J Endocrinol Invest. 2000 Oct;23(9):597-604. Review.


Characterization of mRAD18Sc, a mouse homolog of the yeast postreplication repair gene RAD18.

van der Laan R, Roest HP, Hoogerbrugge JW, Smit EM, Slater R, Baarends WM, Hoeijmakers JH, Grootegoed JA.

Genomics. 2000 Oct 1;69(1):86-94.


The ubiquitin system in gametogenesis.

Baarends WM, Roest HP, Grootegoed JA.

Mol Cell Endocrinol. 1999 May 25;151(1-2):5-16. Review.


Follicle-stimulating hormone and testosterone stimulation of immature and mature Sertoli cells in vitro: inhibin and N-cadherin levels and round spermatid binding.

Lampa J, Hoogerbrugge JW, Baarends WM, Stanton PG, Perryman KJ, Grootegoed JA, Robertson DM.

J Androl. 1999 May-Jun;20(3):399-406.

Supplemental Content

Loading ...
Support Center