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Items: 1 to 50 of 136

1.

FOXO1 transcription factor plays a key role in T cell-HIV-1 interaction.

Roux A, Leroy H, De Muylder B, Bracq L, Oussous S, Dusanter-Fourt I, Chougui G, Tacine R, Randriamampita C, Desjardins D, Le Grand R, Bouillaud F, Benichou S, Margottin-Goguet F, Cheynier R, Bismuth G, Mangeney M.

PLoS Pathog. 2019 May 1;15(5):e1007669. doi: 10.1371/journal.ppat.1007669. eCollection 2019 May.

2.

Antidotal Effects of the Phenothiazine Chromophore Methylene Blue Following Cyanide Intoxication.

Haouzi P, McCann M, Tubbs N, Judenherc-Haouzi A, Cheung J, Bouillaud F.

Toxicol Sci. 2019 Jul 1;170(1):82-94. doi: 10.1093/toxsci/kfz081.

PMID:
30907955
3.

S29434, a Quinone Reductase 2 Inhibitor: Main Biochemical and Cellular Characterization.

Boutin JA, Bouillaud F, Janda E, Gacsalyi I, Guillaumet G, Hirsch EC, Kane DA, Nepveu F, Reybier K, Dupuis P, Bertrand M, Chhour M, Le Diguarher T, Antoine M, Brebner K, Da Costa H, Ducrot P, Giganti A, Goswami V, Guedouari H, Michel PP, Patel A, Paysant J, Stojko J, Viaud-Massuard MC, Ferry G.

Mol Pharmacol. 2019 Mar;95(3):269-285. doi: 10.1124/mol.118.114231. Epub 2018 Dec 19.

PMID:
30567956
4.

Revisiting the physiological effects of methylene blue as a treatment of cyanide intoxication.

Haouzi P, Gueguinou M, Sonobe T, Judenherc-Haouzi A, Tubbs N, Trebak M, Cheung J, Bouillaud F.

Clin Toxicol (Phila). 2018 Sep;56(9):828-840. doi: 10.1080/15563650.2018.1429615. Epub 2018 Feb 16.

PMID:
29451035
5.

DNA repair deficiency sensitizes lung cancer cells to NAD+ biosynthesis blockade.

Touat M, Sourisseau T, Dorvault N, Chabanon RM, Garrido M, Morel D, Krastev DB, Bigot L, Adam J, Frankum JR, Durand S, Pontoizeau C, Souquère S, Kuo MS, Sauvaigo S, Mardakheh F, Sarasin A, Olaussen KA, Friboulet L, Bouillaud F, Pierron G, Ashworth A, Lombès A, Lord CJ, Soria JC, Postel-Vinay S.

J Clin Invest. 2018 Apr 2;128(4):1671-1687. doi: 10.1172/JCI90277. Epub 2018 Mar 19.

6.

Non-toxic fluorescent phosphonium probes to detect mitochondrial potential.

Šarić A, Crnolatac I, Bouillaud F, Sobočanec S, Mikecin AM, Mačak Šafranko Ž, Delgeorgiev T, Piantanida I, Balog T, Petit PX.

Methods Appl Fluoresc. 2017 Mar 22;5(1):015007. doi: 10.1088/2050-6120/aa5e64.

PMID:
28328544
7.

High mTORC1 activity drives glycolysis addiction and sensitivity to G6PD inhibition in acute myeloid leukemia cells.

Poulain L, Sujobert P, Zylbersztejn F, Barreau S, Stuani L, Lambert M, Palama TL, Chesnais V, Birsen R, Vergez F, Farge T, Chenevier-Gobeaux C, Fraisse M, Bouillaud F, Debeissat C, Herault O, Récher C, Lacombe C, Fontenay M, Mayeux P, Maciel TT, Portais JC, Sarry JE, Tamburini J, Bouscary D, Chapuis N.

Leukemia. 2017 Nov;31(11):2326-2335. doi: 10.1038/leu.2017.81. Epub 2017 Mar 10.

PMID:
28280275
8.

Editorial.

Bouillaud F, Casteilla L, Klaus S, Miroux B.

Biochimie. 2017 Mar;134:1-2. doi: 10.1016/j.biochi.2017.01.012. Epub 2017 Jan 29. No abstract available.

PMID:
28143795
9.

Human iPSC-Derived Neural Progenitors Are an Effective Drug Discovery Model for Neurological mtDNA Disorders.

Lorenz C, Lesimple P, Bukowiecki R, Zink A, Inak G, Mlody B, Singh M, Semtner M, Mah N, Auré K, Leong M, Zabiegalov O, Lyras EM, Pfiffer V, Fauler B, Eichhorst J, Wiesner B, Huebner N, Priller J, Mielke T, Meierhofer D, Izsvák Z, Meier JC, Bouillaud F, Adjaye J, Schuelke M, Wanker EE, Lombès A, Prigione A.

Cell Stem Cell. 2017 May 4;20(5):659-674.e9. doi: 10.1016/j.stem.2016.12.013. Epub 2017 Jan 26.

10.

Carbon monoxide reverses the metabolic adaptation of microglia cells to an inflammatory stimulus.

Wilson JL, Bouillaud F, Almeida AS, Vieira HL, Ouidja MO, Dubois-Randé JL, Foresti R, Motterlini R.

Free Radic Biol Med. 2017 Mar;104:311-323. doi: 10.1016/j.freeradbiomed.2017.01.022. Epub 2017 Jan 18.

PMID:
28108277
11.

HK2 Recruitment to Phospho-BAD Prevents Its Degradation, Promoting Warburg Glycolysis by Theileria-Transformed Leukocytes.

Haidar M, Lombès A, Bouillaud F, Kennedy EJ, Langsley G.

ACS Infect Dis. 2017 Mar 10;3(3):216-224. doi: 10.1021/acsinfecdis.6b00180. Epub 2017 Jan 24.

12.

Cytoplasmic proliferating cell nuclear antigen connects glycolysis and cell survival in acute myeloid leukemia.

Ohayon D, De Chiara A, Chapuis N, Candalh C, Mocek J, Ribeil JA, Haddaoui L, Ifrah N, Hermine O, Bouillaud F, Frachet P, Bouscary D, Witko-Sarsat V.

Sci Rep. 2016 Oct 19;6:35561. doi: 10.1038/srep35561.

13.

Muscle expression of a malonyl-CoA-insensitive carnitine palmitoyltransferase-1 protects mice against high-fat/high-sucrose diet-induced insulin resistance.

Vavrova E, Lenoir V, Alves-Guerra MC, Denis RG, Castel J, Esnous C, Dyck JR, Luquet S, Metzger D, Bouillaud F, Prip-Buus C.

Am J Physiol Endocrinol Metab. 2016 Sep 1;311(3):E649-60. doi: 10.1152/ajpendo.00020.2016. Epub 2016 Aug 9.

14.

Positive feedback during sulfide oxidation fine-tunes cellular affinity for oxygen.

Abou-Hamdan A, Ransy C, Roger T, Guedouari-Bounihi H, Galardon E, Bouillaud F.

Biochim Biophys Acta. 2016 Sep;1857(9):1464-1472. doi: 10.1016/j.bbabio.2016.04.282. Epub 2016 Apr 29.

15.

UCPs, at the interface between bioenergetics and metabolism.

Bouillaud F, Alves-Guerra MC, Ricquier D.

Biochim Biophys Acta. 2016 Oct;1863(10):2443-56. doi: 10.1016/j.bbamcr.2016.04.013. Epub 2016 Apr 16. Review.

16.

Detrimental effects for colonocytes of an increased exposure to luminal hydrogen sulfide: The adaptive response.

Beaumont M, Andriamihaja M, Lan A, Khodorova N, Audebert M, Blouin JM, Grauso M, Lancha L, Benetti PH, Benamouzig R, Tomé D, Bouillaud F, Davila AM, Blachier F.

Free Radic Biol Med. 2016 Apr;93:155-64. doi: 10.1016/j.freeradbiomed.2016.01.028. Epub 2016 Feb 2.

PMID:
26849947
17.

Rod-derived cone viability factor promotes cone survival by stimulating aerobic glycolysis.

Aït-Ali N, Fridlich R, Millet-Puel G, Clérin E, Delalande F, Jaillard C, Blond F, Perrocheau L, Reichman S, Byrne LC, Olivier-Bandini A, Bellalou J, Moyse E, Bouillaud F, Nicol X, Dalkara D, van Dorsselaer A, Sahel JA, Léveillard T.

Cell. 2015 May 7;161(4):817-32. doi: 10.1016/j.cell.2015.03.023.

18.

Oxidation of H2S in mammalian cells and mitochondria.

Abou-Hamdan A, Guedouari-Bounihi H, Lenoir V, Andriamihaja M, Blachier F, Bouillaud F.

Methods Enzymol. 2015;554:201-28. doi: 10.1016/bs.mie.2014.11.042. Epub 2015 Jan 22.

PMID:
25725524
19.

Increasing mitochondrial muscle fatty acid oxidation induces skeletal muscle remodeling toward an oxidative phenotype.

Hénique C, Mansouri A, Vavrova E, Lenoir V, Ferry A, Esnous C, Ramond E, Girard J, Bouillaud F, Prip-Buus C, Cohen I.

FASEB J. 2015 Jun;29(6):2473-83. doi: 10.1096/fj.14-257717. Epub 2015 Feb 23.

PMID:
25713059
20.

HIF-1α induction, proliferation and glycolysis of Theileria-infected leukocytes.

Metheni M, Lombès A, Bouillaud F, Batteux F, Langsley G.

Cell Microbiol. 2015 Apr;17(4):467-72. doi: 10.1111/cmi.12421. Epub 2015 Feb 26. Review.

PMID:
25620534
21.

Tissue- and cell-specific mitochondrial defect in Parkin-deficient mice.

Damiano M, Gautier CA, Bulteau AL, Ferrando-Miguel R, Gouarne C, Paoli MG, Pruss R, Auchère F, L'Hermitte-Stead C, Bouillaud F, Brice A, Corti O, Lombès A.

PLoS One. 2014 Jun 24;9(6):e99898. doi: 10.1371/journal.pone.0099898. eCollection 2014.

22.

Oxidation of hydrogen sulfide by human liver mitochondria.

Helmy N, Prip-Buus C, Vons C, Lenoir V, Abou-Hamdan A, Guedouari-Bounihi H, Lombès A, Bouillaud F.

Nitric Oxide. 2014 Sep 15;41:105-12. doi: 10.1016/j.niox.2014.05.011. Epub 2014 Jun 11.

PMID:
24928562
23.

Mitochondrial retrograde signaling mediated by UCP2 inhibits cancer cell proliferation and tumorigenesis.

Esteves P, Pecqueur C, Ransy C, Esnous C, Lenoir V, Bouillaud F, Bulteau AL, Lombès A, Prip-Buus C, Ricquier D, Alves-Guerra MC.

Cancer Res. 2014 Jul 15;74(14):3971-82. doi: 10.1158/0008-5472.CAN-13-3383. Epub 2014 May 22.

24.

Proteasomes associated with the Blm10 activator protein antagonize mitochondrial fission through degradation of the fission protein Dnm1.

Tar K, Dange T, Yang C, Yao Y, Bulteau AL, Salcedo EF, Braigen S, Bouillaud F, Finley D, Schmidt M.

J Biol Chem. 2014 Apr 25;289(17):12145-56. doi: 10.1074/jbc.M114.554105. Epub 2014 Mar 6.

25.

UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation.

Vozza A, Parisi G, De Leonardis F, Lasorsa FM, Castegna A, Amorese D, Marmo R, Calcagnile VM, Palmieri L, Ricquier D, Paradies E, Scarcia P, Palmieri F, Bouillaud F, Fiermonte G.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):960-5. doi: 10.1073/pnas.1317400111. Epub 2014 Jan 6.

26.

WITHDRAWN: Blm10-proteasomes antagonize mitochondrial fission through degradation of Dnm1.

Tar K, Dange T, Yang C, Yao Y, Bulteau AL, Fernandez Salcedo E, Braigen S, Bouillaud F, Finley D, Schmidt M.

J Biol Chem. 2014 Jan 8. [Epub ahead of print]

27.

Mitochondrial uncoupling prevents cold-induced oxidative stress: a case study using UCP1 knockout mice.

Stier A, Bize P, Habold C, Bouillaud F, Massemin S, Criscuolo F.

J Exp Biol. 2014 Feb 15;217(Pt 4):624-30. doi: 10.1242/jeb.092700. Epub 2013 Nov 21.

28.

Episodic weakness due to mitochondrial DNA MT-ATP6/8 mutations.

Auré K, Dubourg O, Jardel C, Clarysse L, Sternberg D, Fournier E, Laforêt P, Streichenberger N, Petiot P, Gervais-Bernard H, Vial C, Bedat-Millet AL, Drouin-Garraud V, Bouillaud F, Vandier C, Fontaine B, Lombès A.

Neurology. 2013 Nov 19;81(21):1810-8. doi: 10.1212/01.wnl.0000436067.43384.0b. Epub 2013 Oct 23.

PMID:
24153443
29.

New biologically active hydrogen sulfide donors.

Roger T, Raynaud F, Bouillaud F, Ransy C, Simonet S, Crespo C, Bourguignon MP, Villeneuve N, Vilaine JP, Artaud I, Galardon E.

Chembiochem. 2013 Nov 25;14(17):2268-71. doi: 10.1002/cbic.201300552. Epub 2013 Oct 2.

PMID:
24115650
30.

The level of H₂O₂ type oxidative stress regulates virulence of Theileria-transformed leukocytes.

Metheni M, Echebli N, Chaussepied M, Ransy C, Chéreau C, Jensen K, Glass E, Batteux F, Bouillaud F, Langsley G.

Cell Microbiol. 2014 Feb;16(2):269-79. doi: 10.1111/cmi.12218. Epub 2013 Oct 21.

31.

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part I. Biochemical and physiological mechanisms.

Szabo C, Ransy C, Módis K, Andriamihaja M, Murghes B, Coletta C, Olah G, Yanagi K, Bouillaud F.

Br J Pharmacol. 2014 Apr;171(8):2099-122. doi: 10.1111/bph.12369. Review.

32.

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects.

Módis K, Bos EM, Calzia E, van Goor H, Coletta C, Papapetropoulos A, Hellmich MR, Radermacher P, Bouillaud F, Szabo C.

Br J Pharmacol. 2014 Apr;171(8):2123-46. doi: 10.1111/bph.12368. Review.

33.

Defective mitochondrial fusion, altered respiratory function, and distorted cristae structure in skin fibroblasts with heterozygous OPA1 mutations.

Agier V, Oliviero P, Lainé J, L'Hermitte-Stead C, Girard S, Fillaut S, Jardel C, Bouillaud F, Bulteau AL, Lombès A.

Biochim Biophys Acta. 2012 Oct;1822(10):1570-80. doi: 10.1016/j.bbadis.2012.07.002. Epub 2012 Jul 16.

34.

Detoxification of H(2)S by differentiated colonic epithelial cells: implication of the sulfide oxidizing unit and of the cell respiratory capacity.

Mimoun S, Andriamihaja M, Chaumontet C, Atanasiu C, Benamouzig R, Blouin JM, Tomé D, Bouillaud F, Blachier F.

Antioxid Redox Signal. 2012 Jul 1;17(1):1-10. doi: 10.1089/ars.2011.4186. Epub 2012 Apr 17.

PMID:
22369066
35.

Glutathionylation acts as a control switch for uncoupling proteins UCP2 and UCP3.

Mailloux RJ, Seifert EL, Bouillaud F, Aguer C, Collins S, Harper ME.

J Biol Chem. 2011 Jun 17;286(24):21865-75. doi: 10.1074/jbc.M111.240242. Epub 2011 Apr 22.

36.

Listeria monocytogenes transiently alters mitochondrial dynamics during infection.

Stavru F, Bouillaud F, Sartori A, Ricquier D, Cossart P.

Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3612-7. doi: 10.1073/pnas.1100126108. Epub 2011 Feb 14.

37.

Mitochondria and sulfide: a very old story of poisoning, feeding, and signaling?

Bouillaud F, Blachier F.

Antioxid Redox Signal. 2011 Jul 15;15(2):379-91. doi: 10.1089/ars.2010.3678. Epub 2011 Apr 20. Review.

PMID:
21028947
38.

Increased ROS production: a component of the longevity equation in the male mygalomorph, Brachypelma albopilosa.

Criscuolo F, Font-Sala C, Bouillaud F, Poulin N, Trabalon M.

PLoS One. 2010 Oct 1;5(10). pii: e13104. doi: 10.1371/journal.pone.0013104.

39.

Increased mitochondrial fatty acid oxidation is sufficient to protect skeletal muscle cells from palmitate-induced apoptosis.

Henique C, Mansouri A, Fumey G, Lenoir V, Girard J, Bouillaud F, Prip-Buus C, Cohen I.

J Biol Chem. 2010 Nov 19;285(47):36818-27. doi: 10.1074/jbc.M110.170431. Epub 2010 Sep 12.

40.

Oxidation of hydrogen sulfide remains a priority in mammalian cells and causes reverse electron transfer in colonocytes.

Lagoutte E, Mimoun S, Andriamihaja M, Chaumontet C, Blachier F, Bouillaud F.

Biochim Biophys Acta. 2010 Aug;1797(8):1500-11. doi: 10.1016/j.bbabio.2010.04.004. Epub 2010 Apr 14.

41.

Cystic fibrosis transmembrane regulator inhibitors CFTR(inh)-172 and GlyH-101 target mitochondrial functions, independently of chloride channel inhibition.

Kelly M, Trudel S, Brouillard F, Bouillaud F, Colas J, Nguyen-Khoa T, Ollero M, Edelman A, Fritsch J.

J Pharmacol Exp Ther. 2010 Apr;333(1):60-9. doi: 10.1124/jpet.109.162032. Epub 2010 Jan 5.

PMID:
20051483
42.

Luminal sulfide and large intestine mucosa: friend or foe?

Blachier F, Davila AM, Mimoun S, Benetti PH, Atanasiu C, Andriamihaja M, Benamouzig R, Bouillaud F, Tomé D.

Amino Acids. 2010 Jul;39(2):335-47. doi: 10.1007/s00726-009-0445-2. Epub 2009 Dec 18. Review.

PMID:
20020161
43.

UCP2, a metabolic sensor coupling glucose oxidation to mitochondrial metabolism?

Pecqueur C, Alves-Guerra C, Ricquier D, Bouillaud F.

IUBMB Life. 2009 Jul;61(7):762-7. doi: 10.1002/iub.188.

44.

UCP2, not a physiologically relevant uncoupler but a glucose sparing switch impacting ROS production and glucose sensing.

Bouillaud F.

Biochim Biophys Acta. 2009 May;1787(5):377-83. doi: 10.1016/j.bbabio.2009.01.003. Epub 2009 Jan 20. Review.

45.

Muscle mitochondrial uncoupling dismantles neuromuscular junction and triggers distal degeneration of motor neurons.

Dupuis L, Gonzalez de Aguilar JL, Echaniz-Laguna A, Eschbach J, Rene F, Oudart H, Halter B, Huze C, Schaeffer L, Bouillaud F, Loeffler JP.

PLoS One. 2009;4(4):e5390. doi: 10.1371/journal.pone.0005390. Epub 2009 Apr 30.

46.

Free radicals run in lizard families: a mitochondrial uncoupling phenomenon or not?

Criscuolo F, Bouillaud F.

Biol Lett. 2009 Jun 23;5(3):343-4. doi: 10.1098/rsbl.2009.0047. Epub 2009 Mar 18. No abstract available.

47.

Mutations in UCP2 in congenital hyperinsulinism reveal a role for regulation of insulin secretion.

González-Barroso MM, Giurgea I, Bouillaud F, Anedda A, Bellanné-Chantelot C, Hubert L, de Keyzer Y, de Lonlay P, Ricquier D.

PLoS One. 2008;3(12):e3850. doi: 10.1371/journal.pone.0003850. Epub 2008 Dec 9.

48.

Modified glutamine catabolism in macrophages of Ucp2 knock-out mice.

Nübel T, Emre Y, Rabier D, Chadefaux B, Ricquier D, Bouillaud F.

Biochim Biophys Acta. 2008 Jan;1777(1):48-54. Epub 2007 Nov 12.

49.

Avian UCP: the killjoy in the evolution of the mitochondrial uncoupling proteins.

Emre Y, Hurtaud C, Ricquier D, Bouillaud F, Hughes J, Criscuolo F.

J Mol Evol. 2007 Oct;65(4):392-402. Epub 2007 Oct 2.

PMID:
17909695
50.

Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysis-derived pyruvate utilization.

Pecqueur C, Bui T, Gelly C, Hauchard J, Barbot C, Bouillaud F, Ricquier D, Miroux B, Thompson CB.

FASEB J. 2008 Jan;22(1):9-18. Epub 2007 Sep 13.

PMID:
17855623

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