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Items: 1 to 50 of 233

1.

Abnormalities in the tricarboxylic acid (TCA) cycle in the brains of schizophrenia patients.

Bubber P, Hartounian V, Gibson GE, Blass JP.

Eur Neuropsychopharmacol. 2011 Mar;21(3):254-60. doi: 10.1016/j.euroneuro.2010.10.007. Epub 2010 Nov 30.

2.

Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases.

Gibson GE, Starkov A, Blass JP, Ratan RR, Beal MF.

Biochim Biophys Acta. 2010 Jan;1802(1):122-34. doi: 10.1016/j.bbadis.2009.08.010. Epub 2009 Aug 26. Review.

3.

A new approach to treating Alzheimer's disease.

Blass JP.

Ann N Y Acad Sci. 2008 Dec;1147:122-8. doi: 10.1196/annals.1427.022. Review.

PMID:
19076437
4.

Intensive nutritional supplements can improve outcomes in stroke rehabilitation.

Rabadi MH, Coar PL, Lukin M, Lesser M, Blass JP.

Neurology. 2008 Dec 2;71(23):1856-61. doi: 10.1212/01.wnl.0000327092.39422.3c. Epub 2008 Oct 22.

PMID:
18946003
5.

Admission C-reactive protein does not predict functional outcomes in patients with strokes in a subacute rehabilitation unit.

Rabadi MH, Coar PL, Lukin M, Lesser M, Blass JP.

Am J Phys Med Rehabil. 2008 Sep;87(9):731-9. doi: 10.1097/PHM.0b013e31818380ae.

PMID:
18716485
6.

Increased levels of gamma-glutamylamines in Huntington disease CSF.

Jeitner TM, Matson WR, Folk JE, Blass JP, Cooper AJ.

J Neurochem. 2008 Jul;106(1):37-44. doi: 10.1111/j.1471-4159.2008.05350.x. Epub 2008 Jul 1.

7.

Randomized clinical stroke trials in 2006.

Rabadi MH, Blass JP.

Curr Vasc Pharmacol. 2008 Jan;6(1):61-6. Review.

PMID:
18220941
8.

Randomized clinical stroke trials in 2007.

Rabadi MH, Blass JP.

Open Neurol J. 2008 Oct 31;2:55-65. doi: 10.2174/1874205X00802010055.

9.

Thiamine-dependent processes and treatment strategies in neurodegeneration.

Gibson GE, Blass JP.

Antioxid Redox Signal. 2007 Oct;9(10):1605-19. Review.

PMID:
17685850
10.

Testing for linkage and association across the dihydrolipoyl dehydrogenase gene region with Alzheimer's disease in three sample populations.

Brown AM, Gordon D, Lee H, Wavrant-De Vrièze F, Cellini E, Bagnoli S, Nacmias B, Sorbi S, Hardy J, Blass JP.

Neurochem Res. 2007 Apr-May;32(4-5):857-69. Epub 2007 Mar 7.

PMID:
17342416
11.
12.

Mitochondrial aconitase is a transglutaminase 2 substrate: transglutamination is a probable mechanism contributing to high-molecular-weight aggregates of aconitase and loss of aconitase activity in Huntington disease brain.

Kim SY, Marekov L, Bubber P, Browne SE, Stavrovskaya I, Lee J, Steinert PM, Blass JP, Beal MF, Gibson GE, Cooper AJ.

Neurochem Res. 2005 Oct;30(10):1245-55.

PMID:
16341586
13.

Commentary on "Diagnosis of Alzheimer's disease: two decades of progress." Perspectives on "Perspectives".

Blass JP.

Alzheimers Dement. 2005 Oct;1(2):124-5. doi: 10.1016/j.jalz.2005.10.003. No abstract available.

PMID:
19595844
14.

What is aging? What is its role in Alzheimer's disease? What can we do about it?

Ashford JW, Atwood CS, Blass JP, Bowen RL, Finch CE, Iqbal K, Joseph JA, Perry G.

J Alzheimers Dis. 2005 Jun;7(3):247-53; discussion 255-62. No abstract available.

PMID:
16006669
15.

The alpha-ketoglutarate-dehydrogenase complex: a mediator between mitochondria and oxidative stress in neurodegeneration.

Gibson GE, Blass JP, Beal MF, Bunik V.

Mol Neurobiol. 2005;31(1-3):43-63. Review.

PMID:
15953811
16.

Transglutaminase activity is present in highly purified nonsynaptosomal mouse brain and liver mitochondria.

Krasnikov BF, Kim SY, McConoughey SJ, Ryu H, Xu H, Stavrovskaya I, Iismaa SE, Mearns BM, Ratan RR, Blass JP, Gibson GE, Cooper AJ.

Biochemistry. 2005 May 31;44(21):7830-43.

17.

Mitochondrial abnormalities in Alzheimer brain: mechanistic implications.

Bubber P, Haroutunian V, Fisch G, Blass JP, Gibson GE.

Ann Neurol. 2005 May;57(5):695-703.

PMID:
15852400
18.

Mitochondrial enzymes in schizophrenia.

Bubber P, Tang J, Haroutunian V, Xu H, Davis KL, Blass JP, Gibson GE.

J Mol Neurosci. 2004;24(2):315-21.

PMID:
15456945
19.

Association of the dihydrolipoamide dehydrogenase gene with Alzheimer's disease in an Ashkenazi Jewish population.

Brown AM, Gordon D, Lee H, Caudy M, Hardy J, Haroutunian V, Blass JP.

Am J Med Genet B Neuropsychiatr Genet. 2004 Nov 15;131B(1):60-6.

PMID:
15389771
20.

Clinically approved heterocyclics act on a mitochondrial target and reduce stroke-induced pathology.

Stavrovskaya IG, Narayanan MV, Zhang W, Krasnikov BF, Heemskerk J, Young SS, Blass JP, Brown AM, Beal MF, Friedlander RM, Kristal BS.

J Exp Med. 2004 Jul 19;200(2):211-22.

21.

Substantial linkage disequilibrium across the dihydrolipoyl succinyltransferase gene region without Alzheimer's disease association.

Brown AM, Gordon D, Lee H, Caudy M, Haroutunian V, Blass JP.

Neurochem Res. 2004 Mar;29(3):629-35.

PMID:
15038610
22.

Cerebrometabolic abnormalities in Alzheimer's disease.

Blass JP.

Neurol Res. 2003 Sep;25(6):556-66. Review.

PMID:
14503009
23.

"Silent" strokes and dementia.

Blass JP, Ratan RR.

N Engl J Med. 2003 Mar 27;348(13):1277-8. No abstract available.

PMID:
12660392
24.

Deficits in a tricarboxylic acid cycle enzyme in brains from patients with Parkinson's disease.

Gibson GE, Kingsbury AE, Xu H, Lindsay JG, Daniel S, Foster OJ, Lees AJ, Blass JP.

Neurochem Int. 2003 Jul;43(2):129-35.

PMID:
12620281
25.

Alzheimer's disease and Alzheimer's dementia: distinct but overlapping entities.

Blass JP.

Neurobiol Aging. 2002 Nov-Dec;23(6):1077-84.

PMID:
12470805
26.

Glucose/mitochondria in neurological conditions.

Blass JP.

Int Rev Neurobiol. 2002;51:325-76. Review.

PMID:
12420364
27.

Cyclin towards, or away from, dementia?

Blass JP.

J Alzheimers Dis. 2002 Jun;4(3):241-2. No abstract available.

PMID:
12226543
28.

The role of the metabolic lesion in Alzheimer's disease.

Blass JP, Gibson GE, Hoyer S.

J Alzheimers Dis. 2002 Jun;4(3):225-32. Review.

PMID:
12226541
29.

Potential for a specific neuroradiologic diagnosis of Alzheimer's disease.

Blass JP.

J Nucl Med. 2002 Aug;43(8):1052-3. No abstract available.

30.

Expression in Escherichia coli and purification of hexahistidine-tagged human tissue transglutaminase.

Shi Q, Kim SY, Blass JP, Cooper AJ.

Protein Expr Purif. 2002 Apr;24(3):366-73.

PMID:
11922752
31.

Selective loss of KGDHC-enriched neurons in Alzheimer temporal cortex: does mitochondrial variation contribute to selective vulnerability?

Ko LW, Sheu KF, Thaler HT, Markesbery WR, Blass JP.

J Mol Neurosci. 2001 Dec;17(3):361-9.

PMID:
11859932
32.
33.

N(epsilon)-(gamma-L-glutamyl)-L-lysine (GGEL) is increased in cerebrospinal fluid of patients with Huntington's disease.

Jeitner TM, Bogdanov MB, Matson WR, Daikhin Y, Yudkoff M, Folk JE, Steinman L, Browne SE, Beal MF, Blass JP, Cooper AJ.

J Neurochem. 2001 Dec;79(5):1109-12.

35.

The role of transglutaminases in neurodegenerative diseases: overview.

Cooper AJ, Jeitner TM, Blass JP.

Neurochem Int. 2002 Jan;40(1):1-5. Review. No abstract available.

PMID:
11738467
36.

A sensitive fluorometric assay for tissue transglutaminase.

Jeitner TM, Fuchsbauer HL, Blass JP, Cooper AJ.

Anal Biochem. 2001 May 15;292(2):198-206.

PMID:
11355851
37.

Correlation of the clinical severity of Alzheimer's disease with an aberration in mitochondrial DNA (mtDNA).

Brown AM, Sheu RK, Mohs R, Haroutunian V, Blass JP.

J Mol Neurosci. 2001 Feb;16(1):41-8.

PMID:
11345519
38.

The mitochondrial spiral. An adequate cause of dementia in the Alzheimer's syndrome.

Blass JP.

Ann N Y Acad Sci. 2000;924:170-83. Review.

PMID:
11193795
39.
40.

Mitochondrial damage in Alzheimer's disease varies with apolipoprotein E genotype.

Gibson GE, Haroutunian V, Zhang H, Park LC, Shi Q, Lesser M, Mohs RC, Sheu RK, Blass JP.

Ann Neurol. 2000 Sep;48(3):297-303.

PMID:
10976635
41.

Inherent abnormalities in energy metabolism in Alzheimer disease. Interaction with cerebrovascular compromise.

Blass JP, Sheu RK, Gibson GE.

Ann N Y Acad Sci. 2000 Apr;903:204-21. Review.

PMID:
10818509
42.

Zn2+ inhibits alpha-ketoglutarate-stimulated mitochondrial respiration and the isolated alpha-ketoglutarate dehydrogenase complex.

Brown AM, Kristal BS, Effron MS, Shestopalov AI, Ullucci PA, Sheu KF, Blass JP, Cooper AJ.

J Biol Chem. 2000 May 5;275(18):13441-7.

44.

Neuronal subclass-selective loss of pyruvate dehydrogenase immunoreactivity following canine cardiac arrest and resuscitation.

Bogaert YE, Sheu KF, Hof PR, Brown AM, Blass JP, Rosenthal RE, Fiskum G.

Exp Neurol. 2000 Jan;161(1):115-26.

PMID:
10683278
45.

The alpha-ketoglutarate dehydrogenase complex in neurodegeneration.

Gibson GE, Park LC, Sheu KF, Blass JP, Calingasan NY.

Neurochem Int. 2000 Feb;36(2):97-112. Review.

PMID:
10676873
46.

Mitochondria, neurodegenerative diseases, and selective neuronal vulnerability.

Blass JP.

Ann N Y Acad Sci. 1999;893:434-9. No abstract available.

PMID:
10672284
47.

The alpha-ketoglutarate dehydrogenase complex.

Sheu KF, Blass JP.

Ann N Y Acad Sci. 1999;893:61-78. Review.

PMID:
10672230
48.

Immunologic treatment of Alzheimer's disease.

Blass JP.

N Engl J Med. 1999 Nov 25;341(22):1694-5. No abstract available.

PMID:
10572162
49.

Cerebrometabolic aspects of delirium in relationship to dementia.

Blass JP, Gibson GE.

Dement Geriatr Cogn Disord. 1999 Sep-Oct;10(5):335-8. Review.

PMID:
10473934
50.

A DLST genotype associated with reduced risk for Alzheimer's disease.

Sheu KF, Brown AM, Kristal BS, Kalaria RN, Lilius L, Lannfelt L, Blass JP.

Neurology. 1999 Apr 22;52(7):1505-7.

PMID:
10227647

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