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Items: 1 to 50 of 190

1.

The succinated proteome.

Merkley ED, Metz TO, Smith RD, Baynes JW, Frizzell N.

Mass Spectrom Rev. 2014 Mar-Apr;33(2):98-109. doi: 10.1002/mas.21382. Epub 2013 Sep 30. Review.

2.

Frontiers in research on the Maillard reaction in aging and chronic disease.

Baynes JW, Gillery P.

Clin Chem Lab Med. 2014 Jan 1;52(1):1-3. doi: 10.1515/cclm-2013-0551. No abstract available.

3.

Chelation therapy: overlooked in the treatment and prevention of diabetes complications?

Frizzell N, Baynes JW.

Future Med Chem. 2013 Jun;5(10):1075-8. doi: 10.4155/fmc.13.73. No abstract available.

4.
5.

Development of an UPLC mass spectrometry method for measurement of myofibrillar protein synthesis: application to analysis of murine muscles during cancer cachexia.

Lima M, Sato S, Enos RT, Baynes JW, Carson JA.

J Appl Physiol (1985). 2013 Mar 15;114(6):824-8. doi: 10.1152/japplphysiol.01141.2012. Epub 2013 Jan 17.

6.

IL-6 regulation on skeletal muscle mitochondrial remodeling during cancer cachexia in the ApcMin/+ mouse.

White JP, Puppa MJ, Sato S, Gao S, Price RL, Baynes JW, Kostek MC, Matesic LE, Carson JA.

Skelet Muscle. 2012 Jul 6;2:14. doi: 10.1186/2044-5040-2-14.

7.

Mitochondrial stress causes increased succination of proteins in adipocytes in response to glucotoxicity.

Frizzell N, Thomas SA, Carson JA, Baynes JW.

Biochem J. 2012 Jul 15;445(2):247-54. doi: 10.1042/BJ20112142.

PMID:
22524437
8.

The effect of exercise on IL-6-induced cachexia in the Apc ( Min/+) mouse.

Puppa MJ, White JP, Velázquez KT, Baltgalvis KA, Sato S, Baynes JW, Carson JA.

J Cachexia Sarcopenia Muscle. 2012 Jun;3(2):117-37. doi: 10.1007/s13539-011-0047-1. Epub 2011 Nov 30.

9.

Chelation: a fundamental mechanism of action of AGE inhibitors, AGE breakers, and other inhibitors of diabetes complications.

Nagai R, Murray DB, Metz TO, Baynes JW.

Diabetes. 2012 Mar;61(3):549-59. doi: 10.2337/db11-1120. Review.

10.

Tissue distribution of S-(2-succino)cysteine (2SC), a biomarker of mitochondrial stress in obesity and diabetes.

Thomas SA, Storey KB, Baynes JW, Frizzell N.

Obesity (Silver Spring). 2012 Feb;20(2):263-9. doi: 10.1038/oby.2011.340. Epub 2011 Dec 1.

11.

The regulation of skeletal muscle protein turnover during the progression of cancer cachexia in the Apc(Min/+) mouse.

White JP, Baynes JW, Welle SL, Kostek MC, Matesic LE, Sato S, Carson JA.

PLoS One. 2011;6(9):e24650. doi: 10.1371/journal.pone.0024650. Epub 2011 Sep 19.

12.

Gut barrier dysfunction in the Apc(Min/+) mouse model of colon cancer cachexia.

Puppa MJ, White JP, Sato S, Cairns M, Baynes JW, Carson JA.

Biochim Biophys Acta. 2011 Dec;1812(12):1601-6. doi: 10.1016/j.bbadis.2011.08.010. Epub 2011 Sep 2.

13.

Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status.

Bardella C, El-Bahrawy M, Frizzell N, Adam J, Ternette N, Hatipoglu E, Howarth K, O'Flaherty L, Roberts I, Turner G, Taylor J, Giaslakiotis K, Macaulay VM, Harris AL, Chandra A, Lehtonen HJ, Launonen V, Aaltonen LA, Pugh CW, Mihai R, Trudgian D, Kessler B, Baynes JW, Ratcliffe PJ, Tomlinson IP, Pollard PJ.

J Pathol. 2011 Sep;225(1):4-11. doi: 10.1002/path.2932. Epub 2011 Jun 1.

PMID:
21630274
14.

Muscle oxidative capacity during IL-6-dependent cancer cachexia.

White JP, Baltgalvis KA, Puppa MJ, Sato S, Baynes JW, Carson JA.

Am J Physiol Regul Integr Comp Physiol. 2011 Feb;300(2):R201-11. doi: 10.1152/ajpregu.00300.2010. Epub 2010 Dec 9.

15.

Succination of proteins in diabetes.

Frizzell N, Lima M, Baynes JW.

Free Radic Res. 2011 Jan;45(1):101-9. doi: 10.3109/10715762.2010.524643. Epub 2010 Oct 22. Review.

PMID:
20964553
16.

Citric acid inhibits development of cataracts, proteinuria and ketosis in streptozotocin (type 1) diabetic rats.

Nagai R, Nagai M, Shimasaki S, Baynes JW, Fujiwara Y.

Biochem Biophys Res Commun. 2010 Feb 26;393(1):118-22. doi: 10.1016/j.bbrc.2010.01.095. Epub 2010 Feb 1.

17.

Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity.

Zhang Y, Ikeno Y, Qi W, Chaudhuri A, Li Y, Bokov A, Thorpe SR, Baynes JW, Epstein C, Richardson A, Van Remmen H.

J Gerontol A Biol Sci Med Sci. 2009 Dec;64(12):1212-20. doi: 10.1093/gerona/glp132. Epub 2009 Sep 23.

18.

Succination of thiol groups in adipose tissue proteins in diabetes: succination inhibits polymerization and secretion of adiponectin.

Frizzell N, Rajesh M, Jepson MJ, Nagai R, Carson JA, Thorpe SR, Baynes JW.

J Biol Chem. 2009 Sep 18;284(38):25772-81. doi: 10.1074/jbc.M109.019257. Epub 2009 Jul 10.

19.

Glycation of wood frog (Rana sylvatica) hemoglobin and blood proteins: in vivo and in vitro studies.

MacDonald JA, Degenhardt T, Baynes JW, Storey KB.

Cryobiology. 2009 Oct;59(2):223-5. doi: 10.1016/j.cryobiol.2009.06.008. Epub 2009 Jun 18.

20.

The metal chelators, trientine and citrate, inhibit the development of cardiac pathology in the Zucker diabetic rat.

Baynes JW, Murray DB.

Exp Diabetes Res. 2009;2009:696378. doi: 10.1155/2009/696378. Epub 2009 Apr 15.

21.

A perspective on the Maillard reaction and the analysis of protein glycation by mass spectrometry: probing the pathogenesis of chronic disease.

Zhang Q, Ames JM, Smith RD, Baynes JW, Metz TO.

J Proteome Res. 2009 Feb;8(2):754-69. doi: 10.1021/pr800858h. Review.

22.

Improved methods for the enrichment and analysis of glycated peptides.

Zhang Q, Schepmoes AA, Brock JW, Wu S, Moore RJ, Purvine SO, Baynes JW, Smith RD, Metz TO.

Anal Chem. 2008 Dec 15;80(24):9822-9. doi: 10.1021/ac801704j.

23.

Succination of proteins by fumarate: mechanism of inactivation of glyceraldehyde-3-phosphate dehydrogenase in diabetes.

Blatnik M, Thorpe SR, Baynes JW.

Ann N Y Acad Sci. 2008 Apr;1126:272-5. doi: 10.1196/annals.1433.047.

24.

Glutaraldehyde is an effective cross-linker for production of antibodies against advanced glycation end-products.

Mera K, Nagai M, Brock JW, Fujiwara Y, Murata T, Maruyama T, Baynes JW, Otagiri M, Nagai R.

J Immunol Methods. 2008 May 20;334(1-2):82-90. doi: 10.1016/j.jim.2008.02.002. Epub 2008 Mar 5.

PMID:
18353354
25.

Increased methionine sulfoxide content of apoA-I in type 1 diabetes.

Brock JW, Jenkins AJ, Lyons TJ, Klein RL, Yim E, Lopes-Virella M, Carter RE; (DCCT/EDIC) Research Group, Thorpe SR, Baynes JW.

J Lipid Res. 2008 Apr;49(4):847-55. doi: 10.1194/jlr.M800015-JLR200. Epub 2008 Jan 17.

27.

Dietary ALEs are a risk to human health--NOT!

Baynes JW.

Mol Nutr Food Res. 2007 Sep;51(9):1102-6.

PMID:
17854007
28.

Succination of protein thiols during adipocyte maturation: a biomarker of mitochondrial stress.

Nagai R, Brock JW, Blatnik M, Baatz JE, Bethard J, Walla MD, Thorpe SR, Baynes JW, Frizzell N.

J Biol Chem. 2007 Nov 23;282(47):34219-28. Epub 2007 Aug 28.

29.

Advanced glycation end products and the absence of premature atherosclerosis in glycogen storage disease Ia.

den Hollander NC, Mulder DJ, Graaff R, Thorpe SR, Baynes JW, Smit GP, Smit AJ.

J Inherit Metab Dis. 2007 Nov;30(6):916-23. Epub 2007 Jun 14.

30.

Enrichment and analysis of nonenzymatically glycated peptides: boronate affinity chromatography coupled with electron-transfer dissociation mass spectrometry.

Zhang Q, Tang N, Brock JW, Mottaz HM, Ames JM, Baynes JW, Smith RD, Metz TO.

J Proteome Res. 2007 Jun;6(6):2323-30. Epub 2007 May 9.

31.

Skin autofluorescence is a strong predictor of cardiac mortality in diabetes.

Meerwaldt R, Lutgers HL, Links TP, Graaff R, Baynes JW, Gans RO, Smit AJ.

Diabetes Care. 2007 Jan;30(1):107-12.

PMID:
17192342
32.

Detection and identification of arginine modifications on methylglyoxal-modified ribonuclease by mass spectrometric analysis.

Brock JW, Cotham WE, Thorpe SR, Baynes JW, Ames JM.

J Mass Spectrom. 2007 Jan;42(1):89-100.

PMID:
17143934
33.

Formation of methionine sulfoxide during glycoxidation and lipoxidation of ribonuclease A.

Brock JW, Ames JM, Thorpe SR, Baynes JW.

Arch Biochem Biophys. 2007 Jan 15;457(2):170-6. Epub 2006 Nov 2.

34.

Advanced glycation end-products and methionine sulphoxide in skin collagen of patients with type 1 diabetes.

Yu Y, Thorpe SR, Jenkins AJ, Shaw JN, Sochaski MA, McGee D, Aston CE, Orchard TJ, Silvers N, Peng YG, McKnight JA, Baynes JW, Lyons TJ; DCCT/EDIC Research Group.

Diabetologia. 2006 Oct;49(10):2488-98. Epub 2006 Aug 29.

PMID:
16955213
35.

Cadmium and mercury cause an oxidative stress-induced endothelial dysfunction.

Wolf MB, Baynes JW.

Biometals. 2007 Feb;20(1):73-81. Epub 2006 Jun 4.

PMID:
16752219
36.

S-(2-Succinyl)cysteine: a novel chemical modification of tissue proteins by a Krebs cycle intermediate.

Alderson NL, Wang Y, Blatnik M, Frizzell N, Walla MD, Lyons TJ, Alt N, Carson JA, Nagai R, Thorpe SR, Baynes JW.

Arch Biochem Biophys. 2006 Jun 1;450(1):1-8. Epub 2006 Mar 22.

PMID:
16624247
37.

What is the future of diabetic wound care?

Sweitzer SM, Fann SA, Borg TK, Baynes JW, Yost MJ.

Diabetes Educ. 2006 Mar-Apr;32(2):197-210. Review.

PMID:
16554422
38.

The anti-cancer drug, doxorubicin, causes oxidant stress-induced endothelial dysfunction.

Wolf MB, Baynes JW.

Biochim Biophys Acta. 2006 Feb;1760(2):267-71. Epub 2005 Nov 28.

PMID:
16337743
39.

Elements of diabetic nephropathy in a patient with GLUT 2 deficiency.

Berry GT, Baynes JW, Wells-Knecht KJ, Szwergold BS, Santer R.

Mol Genet Metab. 2005 Dec;86(4):473-7. Epub 2005 Nov 8.

PMID:
16288895
40.

Skin autofluorescence, a measure of cumulative metabolic stress and advanced glycation end products, predicts mortality in hemodialysis patients.

Meerwaldt R, Hartog JW, Graaff R, Huisman RJ, Links TP, den Hollander NC, Thorpe SR, Baynes JW, Navis G, Gans RO, Smit AJ.

J Am Soc Nephrol. 2005 Dec;16(12):3687-93. Epub 2005 Nov 9.

41.

Tissue-specific variation in glycation of proteins in diabetes: evidence for a functional role of amadoriase enzymes.

Brown SM, Smith DM, Alt N, Thorpe SR, Baynes JW.

Ann N Y Acad Sci. 2005 Jun;1043:817-23. Review.

PMID:
16037309
42.

Dietary bread crust advanced glycation end products bind to the receptor for AGEs in HEK-293 kidney cells but are rapidly excreted after oral administration to healthy and subtotally nephrectomized rats.

Somoza V, Lindenmeier M, Hofmann T, Frank O, Erbersdobler HF, Baynes JW, Thorpe SR, Heidland A, Zill H, Bek S, Huber J, Weigle T, Scheidler S, Busch AE, Sebeková K.

Ann N Y Acad Sci. 2005 Jun;1043:492-500.

PMID:
16037271
43.

Renal effects of oral maillard reaction product load in the form of bread crusts in healthy and subtotally nephrectomized rats.

Sebeková K, Hofmann T, Boor P, Sebeková K Jr, Ulicná O, Erbersdobler HF, Baynes JW, Thorpe SR, Heidland A, Somoza V.

Ann N Y Acad Sci. 2005 Jun;1043:482-91.

PMID:
16037270
44.

Lipid-derived modifications of plasma proteins in experimental and human diabetes.

Januszewski AS, Jenkins AJ, Baynes JW, Thorpe SR.

Ann N Y Acad Sci. 2005 Jun;1043:404-12.

PMID:
16037262
45.

Glycation does not alter LDL-induced secretion of tissue plasminogen activator and plasminogen activator inhibitor-1 from human aortic endothelial cells.

Klein RL, Semler AJ, Baynes JW, Thorpe SR, Lyons TJ, Jenkins AJ.

Ann N Y Acad Sci. 2005 Jun;1043:379-89.

PMID:
16037259
46.

Simple noninvasive measurement of skin autofluorescence.

Meerwaldt R, Links T, Graaff R, Thorpe SR, Baynes JW, Hartog J, Gans R, Smit A.

Ann N Y Acad Sci. 2005 Jun;1043:290-8.

PMID:
16037251
47.

Proteomic method for the quantification of methionine sulfoxide.

Brock JW, Cotham WC, Ames JM, Thorpe SR, Baynes JW.

Ann N Y Acad Sci. 2005 Jun;1043:284-9.

PMID:
16037250
48.

Effect of glucose concentration on formation of AGEs in erythrocytes in vitro.

Nagai R, Deemer EK, Brock JW, Thorpe SR, Baynes JW.

Ann N Y Acad Sci. 2005 Jun;1043:146-50.

PMID:
16037233
49.

The role of AGEs and AGE inhibitors in diabetic cardiovascular disease.

Thomas MC, Baynes JW, Thorpe SR, Cooper ME.

Curr Drug Targets. 2005 Jun;6(4):453-74. Review.

PMID:
16026265
50.

Increased accumulation of skin advanced glycation end-products precedes and correlates with clinical manifestation of diabetic neuropathy.

Meerwaldt R, Links TP, Graaff R, Hoogenberg K, Lefrandt JD, Baynes JW, Gans RO, Smit AJ.

Diabetologia. 2005 Aug;48(8):1637-44. Epub 2005 Jul 14.

PMID:
16021416

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