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Items: 1 to 50 of 78

1.

IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization.

Eissmann MF, Dijkstra C, Jarnicki A, Phesse T, Brunnberg J, Poh AR, Etemadi N, Tsantikos E, Thiem S, Huntington ND, Hibbs ML, Boussioutas A, Grimbaldeston MA, Buchert M, O'Donoghue RJJ, Masson F, Ernst M.

Nat Commun. 2019 Jun 21;10(1):2735. doi: 10.1038/s41467-019-10676-1.

2.

Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth.

Thilakasiri P, Huynh J, Poh AR, Tan CW, Nero TL, Tran K, Parslow AC, Afshar-Sterle S, Baloyan D, Hannan NJ, Buchert M, Scott AM, Griffin MD, Hollande F, Parker MW, Putoczki TL, Ernst M, Chand AL.

EMBO Mol Med. 2019 Apr;11(4). pii: e9539. doi: 10.15252/emmm.201809539.

3.

Correction to: Effect of radiochemotherapy on T2* MRI in HNSCC and its relation to FMISO PET derived hypoxia and FDG PET.

Wiedenmann N, Bunea H, Rischke HC, Bunea A, Majerus L, Bielak L, Protopopov A, Ludwig U, Büchert M, Stoykow C, Nicolay NH, Weber WA, Mix M, Meyer PT, Hennig J, Bock M, Grosu AL.

Radiat Oncol. 2018 Sep 21;13(1):183. doi: 10.1186/s13014-018-1134-7.

4.

Effect of radiochemotherapy on T2* MRI in HNSCC and its relation to FMISO PET derived hypoxia and FDG PET.

Wiedenmann N, Bunea H, Rischke HC, Bunea A, Majerus L, Bielak L, Protopopov A, Ludwig U, Büchert M, Stoykow C, Nicolay NH, Weber WA, Mix M, Meyer PT, Hennig J, Bock M, Grosu AL.

Radiat Oncol. 2018 Aug 29;13(1):159. doi: 10.1186/s13014-018-1103-1. Erratum in: Radiat Oncol. 2018 Sep 21;13(1):183.

5.

MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors.

Sakthianandeswaren A, Parsons MJ, Mouradov D, MacKinnon RN, Catimel B, Liu S, Palmieri M, Love C, Jorissen RN, Li S, Whitehead L, Putoczki TL, Preaudet A, Tsui C, Nowell CJ, Ward RL, Hawkins NJ, Desai J, Gibbs P, Ernst M, Street I, Buchert M, Sieber OM.

Cancer Discov. 2018 Aug;8(8):988-1005. doi: 10.1158/2159-8290.CD-17-0909. Epub 2018 Jun 7.

6.

Electric vehicle recycling 2020: Key component power electronics.

Bulach W, Schüler D, Sellin G, Elwert T, Schmid D, Goldmann D, Buchert M, Kammer U.

Waste Manag Res. 2018 Apr;36(4):311-320. doi: 10.1177/0734242X18759191. Epub 2018 Mar 4.

PMID:
29502494
7.

The JAK/STAT3 axis: A comprehensive drug target for solid malignancies.

Huynh J, Etemadi N, Hollande F, Ernst M, Buchert M.

Semin Cancer Biol. 2017 Aug;45:13-22. doi: 10.1016/j.semcancer.2017.06.001. Epub 2017 Jun 21. Review.

PMID:
28647610
8.

Effects of RF pulse profile and intra-voxel phase dispersion on MR fingerprinting with balanced SSFP readout.

Chiu SC, Lin TM, Lin JM, Chung HW, Ko CW, Büchert M, Bock M.

Magn Reson Imaging. 2017 Sep;41:80-86. doi: 10.1016/j.mri.2017.04.002. Epub 2017 Apr 13.

PMID:
28412455
9.

Generation of an inducible mouse model to reversibly silence Stat3.

Alorro MG, Pierce TP, Eissmann MF, Dijkstra C, Dickins RA, Ernst M, Buchert M, Masson F.

Genesis. 2017 Apr;55(4). doi: 10.1002/dvg.23023. Epub 2017 Feb 23.

PMID:
28170160
10.

Inducible gene modification in the gastric epithelium of Tff1-CreERT2, Tff2-rtTA, Tff3-luc mice.

Thiem S, Eissmann MF, Stuart E, Elzer J, Jonas A, Buchert M, Ernst M.

Genesis. 2016 Dec;54(12):626-635. doi: 10.1002/dvg.22987. Epub 2016 Oct 25.

PMID:
27731922
11.

Biochemical and Structural Insights into Doublecortin-like Kinase Domain 1.

Patel O, Dai W, Mentzel M, Griffin MD, Serindoux J, Gay Y, Fischer S, Sterle S, Kropp A, Burns CJ, Ernst M, Buchert M, Lucet IS.

Structure. 2016 Sep 6;24(9):1550-61. doi: 10.1016/j.str.2016.07.008. Epub 2016 Aug 18.

12.

Stomach-Specific Activation of Oncogenic KRAS and STAT3-Dependent Inflammation Cooperatively Promote Gastric Tumorigenesis in a Preclinical Model.

Thiem S, Eissmann MF, Elzer J, Jonas A, Putoczki TL, Poh A, Nguyen P, Preaudet A, Flanagan D, Vincan E, Waring P, Buchert M, Jarnicki A, Ernst M.

Cancer Res. 2016 Apr 15;76(8):2277-87. doi: 10.1158/0008-5472.CAN-15-3089. Epub 2016 Feb 2.

13.

Endovascular Cooling Catheter for Selective Brain Hypothermia: An Animal Feasibility Study of Cooling Performance.

Cattaneo G, Schumacher M, Maurer C, Wolfertz J, Jost T, Büchert M, Keuler A, Boos L, Shah MJ, Foerster K, Niesen WD, Ihorst G, Urbach H, Meckel S.

AJNR Am J Neuroradiol. 2016 May;37(5):885-91. doi: 10.3174/ajnr.A4625. Epub 2015 Dec 24.

14.

Non-Parametric Bayesian Registration (NParBR) of Body Tumors in DCE-MRI Data.

Pilutti D, Strumia M, Buchert M, Hadjidemetriou S.

IEEE Trans Med Imaging. 2016 Apr;35(4):1025-35. doi: 10.1109/TMI.2015.2506338. Epub 2015 Dec 7.

PMID:
26672032
15.

Internal Fat and Cardiometabolic Risk Factors Following a Meal-Replacement Regimen vs. Comprehensive Lifestyle Changes in Obese Subjects.

König D, Zdzieblik D, Deibert P, Berg A, Gollhofer A, Büchert M.

Nutrients. 2015 Dec 1;7(12):9825-33. doi: 10.3390/nu7125500.

16.

A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations.

Buchert M, Rohde F, Eissmann M, Tebbutt N, Williams B, Tan CW, Owen A, Hirokawa Y, Gnann A, Orend G, Orner G, Dashwood RH, Heath JK, Ernst M, Janssen KP.

Dis Model Mech. 2015 Nov;8(11):1361-73. doi: 10.1242/dmm.019844. Epub 2015 Aug 6.

17.

Glycoprotein A33 deficiency: a new mouse model of impaired intestinal epithelial barrier function and inflammatory disease.

Williams BB, Tebbutt NC, Buchert M, Putoczki TL, Doggett K, Bao S, Johnstone CN, Masson F, Hollande F, Burgess AW, Scott AM, Ernst M, Heath JK.

Dis Model Mech. 2015 Aug 1;8(8):805-15. doi: 10.1242/dmm.019935. Epub 2015 May 8.

18.

Targeting JAK kinase in solid tumors: emerging opportunities and challenges.

Buchert M, Burns CJ, Ernst M.

Oncogene. 2016 Feb 25;35(8):939-51. doi: 10.1038/onc.2015.150. Epub 2015 May 18. Review.

PMID:
25982279
19.

An L1-norm phase constraint for half-Fourier compressed sensing in 3D MR imaging.

Li G, Hennig J, Raithel E, Büchert M, Paul D, Korvink JG, Zaitsev M.

MAGMA. 2015 Oct;28(5):459-72. doi: 10.1007/s10334-015-0482-7. Epub 2015 Feb 26.

PMID:
25712732
20.

Incorporation of image data from a previous examination in 3D serial MR imaging.

Li G, Hennig J, Raithel E, Büchert M, Paul D, Korvink JG, Zaitsev M.

MAGMA. 2015 Oct;28(5):413-25. doi: 10.1007/s10334-014-0478-8. Epub 2015 Jan 9.

PMID:
25572444
21.

Improving the robustness of 3D turbo spin echo imaging to involuntary motion.

Li G, Zaitsev M, Büchert M, Raithel E, Paul D, Korvink JG, Hennig J.

MAGMA. 2015 Aug;28(4):329-45. doi: 10.1007/s10334-014-0471-2. Epub 2014 Nov 20.

PMID:
25408109
22.

Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration.

Phesse TJ, Buchert M, Stuart E, Flanagan DJ, Faux M, Afshar-Sterle S, Walker F, Zhang HH, Nowell CJ, Jorissen R, Tan CW, Hirokawa Y, Eissmann MF, Poh AR, Malaterre J, Pearson HB, Kirsch DG, Provero P, Poli V, Ramsay RG, Sieber O, Burgess AW, Huszar D, Vincan E, Ernst M.

Sci Signal. 2014 Sep 30;7(345):ra92. doi: 10.1126/scisignal.2005411.

23.

2,2'-Bipyridine-based dendritic structured compounds for second harmonic generation.

Büchert M, Steenbock T, Lukaschek C, Wolff MC, Herrmann C, Heck J.

Chemistry. 2014 Oct 27;20(44):14351-61. doi: 10.1002/chem.201404001. Epub 2014 Sep 22.

PMID:
25251846
24.

In vitro study to simulate the intracardiac magnetohydrodynamic effect.

Buchenberg WB, Mader W, Hoppe G, Lorenz R, Menza M, Büchert M, Timmer J, Jung B.

Magn Reson Med. 2015 Sep;74(3):850-7. doi: 10.1002/mrm.25456. Epub 2014 Sep 15.

PMID:
25224650
25.

Vascular effects, efficacy and safety of nintedanib in patients with advanced, refractory colorectal cancer: a prospective phase I subanalysis.

Mross K, Büchert M, Frost A, Medinger M, Stopfer P, Studeny M, Kaiser R.

BMC Cancer. 2014 Jul 11;14:510. doi: 10.1186/1471-2407-14-510.

26.

FOLFIRI and sunitinib as first-line treatment in metastatic colorectal cancer patients with liver metastases--a CESAR phase II study including pharmacokinetic, biomarker, and imaging data.

Mross K, Scheulen M, Strumberg D, Kuhlmann J, Kanefendt F, Sörgel F, Jaehde U, Burkholder I, Moritz B, Büchert M.

Int J Clin Pharmacol Ther. 2014 Aug;52(8):642-52. doi: 10.5414/CP202109.

PMID:
24800922
27.

Whole-body MRI-based fat quantification: a comparison to air displacement plethysmography.

Ludwig UA, Klausmann F, Baumann S, Honal M, Hövener JB, König D, Deibert P, Büchert M.

J Magn Reson Imaging. 2014 Dec;40(6):1437-44. doi: 10.1002/jmri.24509. Epub 2014 Jan 22.

PMID:
24449401
28.

Therapeutic inhibition of Jak activity inhibits progression of gastrointestinal tumors in mice.

Stuart E, Buchert M, Putoczki T, Thiem S, Farid R, Elzer J, Huszar D, Waring PM, Phesse TJ, Ernst M.

Mol Cancer Ther. 2014 Feb;13(2):468-74. doi: 10.1158/1535-7163.MCT-13-0583-T. Epub 2014 Jan 7.

29.

First-in-human phase I study of PRS-050 (Angiocal), an Anticalin targeting and antagonizing VEGF-A, in patients with advanced solid tumors.

Mross K, Richly H, Fischer R, Scharr D, Büchert M, Stern A, Gille H, Audoly LP, Scheulen ME.

PLoS One. 2013 Dec 13;8(12):e83232. doi: 10.1371/journal.pone.0083232. eCollection 2013.

30.

Registration of abdominal tumor DCE-MRI data based on deconvolution of joint statistics.

Pilutti D, Büchert M, Hadjidemetriou S.

Conf Proc IEEE Eng Med Biol Soc. 2013;2013:2611-4. doi: 10.1109/EMBC.2013.6610075.

PMID:
24110262
31.

mTORC1 inhibition restricts inflammation-associated gastrointestinal tumorigenesis in mice.

Thiem S, Pierce TP, Palmieri M, Putoczki TL, Buchert M, Preaudet A, Farid RO, Love C, Catimel B, Lei Z, Rozen S, Gopalakrishnan V, Schaper F, Hallek M, Boussioutas A, Tan P, Jarnicki A, Ernst M.

J Clin Invest. 2013 Feb;123(2):767-81. doi: 10.1172/JCI65086. Epub 2013 Jan 16.

32.

Regorafenib (BAY 73-4506) in advanced colorectal cancer: a phase I study.

Strumberg D, Scheulen ME, Schultheis B, Richly H, Frost A, Büchert M, Christensen O, Jeffers M, Heinig R, Boix O, Mross K.

Br J Cancer. 2012 May 22;106(11):1722-7. doi: 10.1038/bjc.2012.153. Epub 2012 May 8.

33.

A phase I dose-escalation study of regorafenib (BAY 73-4506), an inhibitor of oncogenic, angiogenic, and stromal kinases, in patients with advanced solid tumors.

Mross K, Frost A, Steinbild S, Hedbom S, Büchert M, Fasol U, Unger C, Krätzschmar J, Heinig R, Boix O, Christensen O.

Clin Cancer Res. 2012 May 1;18(9):2658-67. doi: 10.1158/1078-0432.CCR-11-1900. Epub 2012 Mar 15.

34.

Methods to examine tight junction physiology in cancer stem cells: TEER, paracellular permeability, and dilution potential measurements.

Buchert M, Turksen K, Hollande F.

Stem Cell Rev Rep. 2012 Sep;8(3):1030-4. doi: 10.1007/s12015-011-9334-7.

PMID:
22134928
35.

Phase I study of telatinib (BAY 57-9352): analysis of safety, pharmacokinetics, tumor efficacy, and biomarkers in patients with colorectal cancer.

Mross K, Frost A, Scheulen ME, Krauss J, Strumberg D, Schultheiss B, Fasol U, Büchert M, Krätzschmer J, Delesen H, Rajagopalan P, Christensen O.

Vasc Cell. 2011 Jul 29;3:16. doi: 10.1186/2045-824X-3-16.

36.

Vascular and pharmacokinetic effects of EndoTAG-1 in patients with advanced cancer and liver metastasis.

Fasol U, Frost A, Büchert M, Arends J, Fiedler U, Scharr D, Scheuenpflug J, Mross K.

Ann Oncol. 2012 Apr;23(4):1030-6. doi: 10.1093/annonc/mdr300. Epub 2011 Jun 21.

PMID:
21693769
37.

Magnetic resonance spectroscopy of the anterior cingulate cortex in eating disorders.

Joos AA, Perlov E, Büchert M, Hartmann A, Saum B, Glauche V, Freyer T, Weber-Fahr W, Zeeck A, Tebartz van Elst L.

Psychiatry Res. 2011 Mar 31;191(3):196-200. doi: 10.1016/j.pscychresns.2010.10.004.

PMID:
21310595
38.

A preliminary report of a Phase II study of folinic acid, 5-fluorouracil, irinotecan (FOLFIRI) plus sunitinib with toxicity, efficacy, pharmacokinetics, biomarker, imaging data in patients with colorectal cancer with liver metastases as 1st line treatment.

Mross K, Büchert M, Fasol U, Jaehde U, Kanefendt F, Strumberg D, Arends J, Hense J, Moritz B, Fischer R, Scheulen ME.

Int J Clin Pharmacol Ther. 2011 Jan;49(1):96-8. No abstract available.

PMID:
21176744
39.

Effects of athletic conditioning on horses with degenerative suspensory ligament desmitis: a preliminary report.

Xie L, Spencer ND, Beadle RE, Gaschen L, Buchert MR, Lopez MJ.

Vet J. 2011 Jul;189(1):49-57. doi: 10.1016/j.tvjl.2010.06.010. Epub 2010 Jul 23.

PMID:
20655251
40.

Everolimus in patients with autosomal dominant polycystic kidney disease.

Walz G, Budde K, Mannaa M, Nürnberger J, Wanner C, Sommerer C, Kunzendorf U, Banas B, Hörl WH, Obermüller N, Arns W, Pavenstädt H, Gaedeke J, Büchert M, May C, Gschaidmeier H, Kramer S, Eckardt KU.

N Engl J Med. 2010 Aug 26;363(9):830-40. doi: 10.1056/NEJMoa1003491. Epub 2010 Jun 26. Erratum in: N Engl J Med. 2010 Nov 11;363(20):1977. N Engl J Med. 2010 Sep 16;363(12):1190.

41.

Neurochemical alterations in women with borderline personality disorder and comorbid attention-deficit hyperactivity disorder.

Rüsch N, Boeker M, Büchert M, Glauche V, Bohrmann C, Ebert D, Lieb K, Hennig J, Tebartz Van Elst L.

World J Biol Psychiatry. 2010 Mar;11(2 Pt 2):372-81. doi: 10.3109/15622970801958331.

PMID:
20218799
42.

Symplekin promotes tumorigenicity by up-regulating claudin-2 expression.

Buchert M, Papin M, Bonnans C, Darido C, Raye WS, Garambois V, Pélegrin A, Bourgaux JF, Pannequin J, Joubert D, Hollande F.

Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2628-33. doi: 10.1073/pnas.0903747107. Epub 2010 Jan 25.

43.

Single-voxel MRS with prospective motion correction and retrospective frequency correction.

Zaitsev M, Speck O, Hennig J, Büchert M.

NMR Biomed. 2010 Apr;23(3):325-32. doi: 10.1002/nbm.1469.

PMID:
20101605
44.

Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo.

Buchert M, Athineos D, Abud HE, Burke ZD, Faux MC, Samuel MS, Jarnicki AG, Winbanks CE, Newton IP, Meniel VS, Suzuki H, Stacker SA, Näthke IS, Tosh D, Huelsken J, Clarke AR, Heath JK, Sansom OJ, Ernst M.

PLoS Genet. 2010 Jan 15;6(1):e1000816. doi: 10.1371/journal.pgen.1000816.

45.

DCE-MRI assessment of the effect of vandetanib on tumor vasculature in patients with advanced colorectal cancer and liver metastases: a randomized phase I study.

Mross K, Fasol U, Frost A, Benkelmann R, Kuhlmann J, Büchert M, Unger C, Blum H, Hennig J, Milenkova TP, Tessier J, Krebs AD, Ryan AJ, Fischer R.

J Angiogenes Res. 2009 Sep 21;1:5. doi: 10.1186/2040-2384-1-5.

46.

Elevated Dnmt3a activity promotes polyposis in Apc(Min) mice by relaxing extracellular restraints on Wnt signaling.

Samuel MS, Suzuki H, Buchert M, Putoczki TL, Tebbutt NC, Lundgren-May T, Christou A, Inglese M, Toyota M, Heath JK, Ward RL, Waring PM, Ernst M.

Gastroenterology. 2009 Sep;137(3):902-13, 913.e1-11. doi: 10.1053/j.gastro.2009.05.042. Epub 2009 May 18.

PMID:
19454286
47.

The symplekin/ZONAB complex inhibits intestinal cell differentiation by the repression of AML1/Runx1.

Buchert M, Darido C, Lagerqvist E, Sedello A, Cazevieille C, Buchholz F, Bourgaux JF, Pannequin J, Joubert D, Hollande F.

Gastroenterology. 2009 Jul;137(1):156-64, 164.e1-3. doi: 10.1053/j.gastro.2009.03.037. Epub 2009 Mar 27.

PMID:
19328795
48.

Vitamin C estimation with standard (1)H spectroscopy using a clinical 3T MR system: detectability and reliability within the human brain.

Shih YY, Büchert M, Chung HW, Hennig J, von Elverfeldt D.

J Magn Reson Imaging. 2008 Aug;28(2):351-8. doi: 10.1002/jmri.21466.

PMID:
18666156
49.

Defective claudin-7 regulation by Tcf-4 and Sox-9 disrupts the polarity and increases the tumorigenicity of colorectal cancer cells.

Darido C, Buchert M, Pannequin J, Bastide P, Zalzali H, Mantamadiotis T, Bourgaux JF, Garambois V, Jay P, Blache P, Joubert D, Hollande F.

Cancer Res. 2008 Jun 1;68(11):4258-68. doi: 10.1158/0008-5472.CAN-07-5805.

50.

STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice.

Ernst M, Najdovska M, Grail D, Lundgren-May T, Buchert M, Tye H, Matthews VB, Armes J, Bhathal PS, Hughes NR, Marcusson EG, Karras JG, Na S, Sedgwick JD, Hertzog PJ, Jenkins BJ.

J Clin Invest. 2008 May;118(5):1727-38. doi: 10.1172/JCI34944.

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