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High CXCR4 expression impairs rituximab response and the prognosis of R-CHOP-treated diffuse large B-cell lymphoma patients.

Laursen MB, Reinholdt L, Schönherz AA, Due H, Jespersen DS, Grubach L, Ettrup MS, Røge R, Falgreen S, Sørensen S, Bødker JS, Schmitz A, Johnsen HE, Bøgsted M, Dybkær K.

Oncotarget. 2019 Jan 22;10(7):717-731. doi: 10.18632/oncotarget.26588. eCollection 2019 Jan 22.


Relapse Risk and Loss of Lifetime After Modern Combined Modality Treatment of Young Patients With Hodgkin Lymphoma: A Nordic Lymphoma Epidemiology Group Study.

Biccler JL, Glimelius I, Eloranta S, Smeland KB, Brown PN, Jakobsen LH, Frederiksen H, Jerkeman M, Fosså A, Andersson TML, Holte H, Bøgsted M, El-Galaly TC, Smedby KE.

J Clin Oncol. 2019 Feb 6:JCO1801652. doi: 10.1200/JCO.18.01652. [Epub ahead of print]


Estimating the loss of lifetime function using flexible parametric relative survival models.

Jakobsen LH, Andersson TM, Biccler JL, El-Galaly TC, Bøgsted M.

BMC Med Res Methodol. 2019 Jan 28;19(1):23. doi: 10.1186/s12874-019-0661-8.


Expression of NOTCH3 exon 16 differentiates Diffuse Large B-cell Lymphoma into molecular subtypes and is associated with prognosis.

Jespersen DS, Schönherz AA, Due H, Bøgsted M, Sondergaard TE, Dybkær K.

Sci Rep. 2019 Jan 23;9(1):335. doi: 10.1038/s41598-018-36680-x.


Optimizing Outcome Prediction in Diffuse Large B-Cell Lymphoma by Use of Machine Learning and Nationwide Lymphoma Registries: A Nordic Lymphoma Group Study.

Biccler JL, Eloranta S, de Nully Brown P, Frederiksen H, Jerkeman M, Jørgensen J, Jakobsen LH, Smedby KE, Bøgsted M, El-Galaly TC.

JCO Clin Cancer Inform. 2018 Dec;2:1-13. doi: 10.1200/CCI.18.00025.


Limited value of routine follow-up visits in chronic lymphocytic leukemia managed initially by watch and wait: A North Denmark population-based study.

Nørgaard CH, Søgaard NB, Biccler JL, Pilgaard L, Eskesen MH, Kjartansdottir TH, Bøgsted M, El-Galaly TC.

PLoS One. 2018 Dec 27;13(12):e0208180. doi: 10.1371/journal.pone.0208180. eCollection 2018.


Clinical prognostic scores are poor predictors of overall survival in various types of malignant lymphomas.

Biccler JL, El-Galaly TC, Bøgsted M, Jørgensen J, de Nully Brown P, Poulsen CB, Starklint J, Juul MB, Christensen JH, Josefsson P, Dessau A, Jakobsen LH.

Leuk Lymphoma. 2018 Nov 14:1-4. doi: 10.1080/10428194.2018.1540044. [Epub ahead of print] No abstract available.


A multiple myeloma classification system that associates normal B-cell subset phenotypes with prognosis.

Bødker JS, Brøndum RF, Schmitz A, Schönherz AA, Jespersen DS, Sønderkær M, Vesteghem C, Due H, Nørgaard CH, Perez-Andres M, Samur MK, Davies F, Walker B, Pawlyn C, Kaiser M, Johnson D, Bertsch U, Broyl A, van Duin M, Shah R, Johansen P, Nørgaard MA, Samworth RJ, Sonneveld P, Goldschmidt H, Morgan GJ, Orfao A, Munshi N, Johnson HE, El-Galaly T, Dybkær K, Bøgsted M.

Blood Adv. 2018 Sep 25;2(18):2400-2411. doi: 10.1182/bloodadvances.2018018564.


Early mobilisation of patients with community-acquired pneumonia reduce length of hospitalisation-a pilot study.

Melgaard D, Baandrup U, Bøgsted M, Bendtsen MD, Kristensen MT.

J Phys Ther Sci. 2018 Jul;30(7):926-932. doi: 10.1589/jpts.30.926. Epub 2018 Jul 3.


Non-occupational exposure to asbestos is the main cause of malignant mesothelioma in women in North Jutland, Denmark.

Panou V, Vyberg M, Meristoudis C, Hansen J, Bøgsted M, Omland Ø, Weinreich UM, Røe OD.

Scand J Work Environ Health. 2019 Jan 1;45(1):82-89. doi: 10.5271/sjweh.3756. Epub 2018 Jul 19.


A B-cell-associated gene signature classification of diffuse large B-cell lymphoma by NanoString technology.

Michaelsen TY, Richter J, Brøndum RF, Klapper W, Johnsen HE, Albertsen M, Dybkær K, Bøgsted M.

Blood Adv. 2018 Jul 10;2(13):1542-1546. doi: 10.1182/bloodadvances.2018017988.


Six cycles of R-CHOP-21 are not inferior to eight cycles for treatment of diffuse large B-cell lymphoma: a Nordic Lymphoma Group Population-based Study.

Wästerlid T, Biccler JL, Brown PN, Bøgsted M, Enblad G, Mészáros Jørgensen J, Christensen JH, Wahlin BE, Smedby KE, El-Galaly TC, Jerkeman M.

Ann Oncol. 2018 Aug 1;29(8):1882-1883. doi: 10.1093/annonc/mdy184. No abstract available.


Stringent or nonstringent complete remission and prognosis in acute myeloid leukemia: a Danish population-based study.

Øvlisen AK, Oest A, Bendtsen MD, Bæch J, Johansen P, Lynggaard LS, Mølle I, Mortensen TB, Weber D, Ertner G, Schöllkopf C, Thomassen JQ, Nielsen OJ, Østgård LSG, Bøgsted M, Dybkær K, Johnsen HE, Severinsen MT.

Blood Adv. 2018 Mar 13;2(5):559-564. doi: 10.1182/bloodadvances.2017007393.


Subtype assignment of CLL based on B-cell subset associated gene signatures from normal bone marrow - A proof of concept study.

Nørgaard CH, Jakobsen LH, Gentles AJ, Dybkær K, El-Galaly TC, Bødker JS, Schmitz A, Johansen P, Herold T, Spiekermann K, Brown JR, Klitgaard JL, Johnsen HE, Bøgsted M.

PLoS One. 2018 Mar 7;13(3):e0193249. doi: 10.1371/journal.pone.0193249. eCollection 2018.


Evolution of relative survival for acute promyelocytic leukemia patients alive at landmark time-points: a population-based study.

Biccler JL, Østgård LSG, Severinsen MT, Marcher CW, Møller P, Schöllkopf C, Friis LS, Bøgsted M, Jakobsen LH, El-Galaly TC, Nørgaard JM.

Leukemia. 2018 Oct;32(10):2263-2303. doi: 10.1038/s41375-018-0054-8. Epub 2018 Feb 23. No abstract available.


Is the accuracy of preoperative MRI stage in rectal adenocarcinoma influenced by tumour height?

Poulsen LØ, Yilmaz MK, Oddershede L, Bøgsted M, Holt G, Eld M, Ljungmann K, Falkmer UG.

Acta Oncol. 2018 Jun;57(6):728-734. doi: 10.1080/0284186X.2018.1433319. Epub 2018 Jan 31.


Oral mucosa tissue gene expression profiling before, during, and after radiation therapy for tonsil squamous cell carcinoma.

Marcussen M, Sønderkær M, Bødker JS, Andersen M, Nielsen S, Vesteghem C, Christiansen I, Bergmann OJ, Bøgsted M, Dybkær K, Vyberg M, Johnsen HE.

PLoS One. 2018 Jan 16;13(1):e0190709. doi: 10.1371/journal.pone.0190709. eCollection 2018.


Superior Reproducibility of the Leading to Leading Edge and Inner to Inner Edge Methods in the Ultrasound Assessment of Maximum Abdominal Aortic Diameter.

Borgbjerg J, Bøgsted M, Lindholt JS, Behr-Rasmussen C, Hørlyck A, Frøkjær JB.

Eur J Vasc Endovasc Surg. 2018 Feb;55(2):206-213. doi: 10.1016/j.ejvs.2017.11.019. Epub 2017 Dec 23.


Simplicity at the cost of predictive accuracy in diffuse large B-cell lymphoma: a critical assessment of the R-IPI, IPI, and NCCN-IPI.

Biccler J, Eloranta S, de Nully Brown P, Frederiksen H, Jerkeman M, Smedby KE, Bøgsted M, El-Galaly TC.

Cancer Med. 2018 Jan;7(1):114-122. doi: 10.1002/cam4.1271. Epub 2017 Dec 13. Erratum in: Cancer Med. 2018 Apr;7(4):1572.


Proteomics dataset: The colon mucosa from inflammatory bowel disease patients, gastrointestinal asymptomic rheumatoid arthritis patients, and controls.

Bennike TB, Carlsen TG, Ellingsen T, Bonderup OK, Glerup H, Bøgsted M, Christiansen G, Birkelund S, Andersen V, Stensballe A.

Data Brief. 2017 Oct 6;15:511-516. doi: 10.1016/j.dib.2017.09.059. eCollection 2017 Dec.


A systematic review of molecular responses to cancer therapy in normal human mucosa.

Marcussen M, Skrubbeltrang C, Bødker JS, Christiansen I, Bøgsted M, Dybkær K, Bergmann OJ, Johnsen HE.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2017 Oct;124(4):355-366. doi: 10.1016/j.oooo.2017.08.002. Epub 2017 Aug 15. Review.


Real world data on rituximab maintenance therapy after frontline immunochemotherapy in grade 1-3a follicular lymphoma.

Bech RS, Nielsen KL, Larsen TS, Bentzen HH, Lynggaard LS, Do TH, Braendstrup P, Brady J, Mikhaeel NG, Dybkaer K, Johnsen HE, Jensen P, Bøgsted M, El-Galaly TC.

Br J Haematol. 2018 Jul;182(2):297-301. doi: 10.1111/bjh.14775. Epub 2017 May 23. No abstract available.


Interactions between SNPs affecting inflammatory response genes are associated with multiple myeloma disease risk and survival.

Nielsen KR, Rodrigo-Domingo M, Steffensen R, Baech J, Bergkvist KS, Oosterhof L, Schmitz A, Bødker JS, Johansen P, Vogel U, Vangsted A, Dybkær K, Bøgsted M, Johnsen HE.

Leuk Lymphoma. 2017 Nov;58(11):2695-2704. doi: 10.1080/10428194.2017.1306643. Epub 2017 Apr 9.


Outcome of peripheral T-cell lymphoma in first complete remission: a Danish-Swedish population-based study.

Cederleuf H, Hjort Jakobsen L, Ellin F, de Nully Brown P, Stauffer Larsen T, Bøgsted M, Relander T, Jerkeman M, El-Galaly TC.

Leuk Lymphoma. 2017 Dec;58(12):2815-2823. doi: 10.1080/10428194.2017.1300888. Epub 2017 Mar 20.


The number of extranodal sites assessed by PET/CT scan is a powerful predictor of CNS relapse for patients with diffuse large B-cell lymphoma: An international multicenter study of 1532 patients treated with chemoimmunotherapy.

El-Galaly TC, Villa D, Michaelsen TY, Hutchings M, Mikhaeel NG, Savage KJ, Sehn LH, Barrington S, Hansen JW, Smith D, Rady K, Mylam KJ, Larsen TS, Holmberg S, Juul MB, Cordua S, Clausen MR, Jensen KB, Johnsen HE, Seymour JF, Connors JM, de Nully Brown P, Bøgsted M, Cheah CY.

Eur J Cancer. 2017 Apr;75:195-203. doi: 10.1016/j.ejca.2016.12.029. Epub 2017 Feb 23.


Molecular classification of tissue from a transformed non-Hogkin's lymphoma case with unexpected long-time remission.

Bødker JS, Severinsen MT, El-Galaly TC, Brøndum RF, Laursen MB, Falgreen S, Nyegaard M, Schmitz A, Jakobsen LH, Schönherz AA, Due H, Reinholdt L, Bøgsted M, Dybkær K, Johnsen HE.

Exp Hematol Oncol. 2017 Jan 11;6:3. doi: 10.1186/s40164-016-0063-0. eCollection 2017.


Minimal Loss of Lifetime for Patients With Diffuse Large B-Cell Lymphoma in Remission and Event Free 24 Months After Treatment: A Danish Population-Based Study.

Jakobsen LH, Bøgsted M, Brown PN, Arboe B, Jørgensen J, Larsen TS, Juul MB, Schurmann L, Højberg L, Bergmann OJ, Lassen T, Josefsson PL, Jensen P, Johnsen HE, El-Galaly TC.

J Clin Oncol. 2017 Mar;35(7):778-784. doi: 10.1200/JCO.2016.70.0765. Epub 2017 Jan 17.


Molecular Characteristics of High-Dose Melphalan Associated Oral Mucositis in Patients with Multiple Myeloma: A Gene Expression Study on Human Mucosa.

Marcussen M, Bødker JS, Christensen HS, Johansen P, Nielsen S, Christiansen I, Bergmann OJ, Bøgsted M, Dybkær K, Vyberg M, Johnsen HE.

PLoS One. 2017 Jan 4;12(1):e0169286. doi: 10.1371/journal.pone.0169286. eCollection 2017.


The Prevalence of Oropharyngeal Dysphagia in Danish Patients Hospitalised with Community-Acquired Pneumonia.

Melgaard D, Baandrup U, Bøgsted M, Bendtsen MD, Hansen T.

Dysphagia. 2017 Jun;32(3):383-392. doi: 10.1007/s00455-016-9765-z. Epub 2016 Dec 22.


The myeloma stem cell concept, revisited: from phenomenology to operational terms.

Johnsen HE, Bøgsted M, Schmitz A, Bødker JS, El-Galaly TC, Johansen P, Valent P, Zojer N, Van Valckenborgh E, Vanderkerken K, van Duin M, Sonneveld P, Perez-Andres M, Orfao A, Dybkær K.

Haematologica. 2016 Dec;101(12):1451-1459. Epub 2016 Nov 10. Review.


Anthropometrics and prognosis in diffuse large B-cell lymphoma: a multicentre study of 653 patients.

Bendtsen MD, Munksgaard PS, Severinsen MT, Bekric E, Brieghel C, Nielsen KB, Brown PN, Dybkaer K, Johnsen HE, Bøgsted M, El-Galaly TC.

Eur J Haematol. 2017 Apr;98(4):355-362. doi: 10.1111/ejh.12835. Epub 2017 Jan 31.


R-CHOP(-like) treatment of diffuse large B-cell lymphoma significantly reduces CT-assessed vertebral bone density: a single center study of 111 patients.

Svendsen P, Shekhrajka N, Nielsen KL, Vestergaard P, Poulsen MØ, Vistisen AK, Munksgaard PS, Severinsen MT, Jensen P, Johnsen HE, Jakobsen LH, Bøgsted M, Frøkjær JB, El-Galaly TC.

Leuk Lymphoma. 2017 May;58(5):1105-1113. doi: 10.1080/10428194.2016.1233543. Epub 2016 Oct 13.

33. Online One-By-One Microarray Normalization and Classification of Hematological Cancers for Precision Medicine.

Falgreen S, Ellern Bilgrau A, Brøndum RF, Hjort Jakobsen L, Have J, Lindblad Nielsen K, El-Galaly TC, Bødker JS, Schmitz A, H Young K, Johnsen HE, Dybkær K, Bøgsted M.

PLoS One. 2016 Oct 4;11(10):e0163711. doi: 10.1371/journal.pone.0163711. eCollection 2016.


Uterine, but not ovarian, female reproductive organ involvement at presentation by diffuse large B-cell lymphoma is associated with poor outcomes and a high frequency of secondary CNS involvement.

El-Galaly TC, Cheah CY, Hutchings M, Mikhaeel NG, Savage KJ, Sehn LH, Barrington S, Hansen JW, Poulsen MØ, Smith D, Rady K, Mylam KJ, Larsen TS, Holmberg S, Juul MB, Cordua S, Clausen MR, Jensen KB, Bøgsted M, Johnsen HE, Seymour JF, Connors JM, Brown PD, Villa D.

Br J Haematol. 2016 Dec;175(5):876-883. doi: 10.1111/bjh.14325. Epub 2016 Sep 29.


Proteome Analysis of Rheumatoid Arthritis Gut Mucosa.

Bennike TB, Ellingsen T, Glerup H, Bonderup OK, Carlsen TG, Meyer MK, Bøgsted M, Christiansen G, Birkelund S, Andersen V, Stensballe A.

J Proteome Res. 2017 Jan 6;16(1):346-354. doi: 10.1021/acs.jproteome.6b00598. Epub 2016 Sep 27.


Retinal proteome changes following experimental branch retinal vein occlusion and intervention with ranibizumab.

Cehofski LJ, Kruse A, Bøgsted M, Magnusdottir SO, Stensballe A, Honoré B, Vorum H.

Exp Eye Res. 2016 Nov;152:49-56. doi: 10.1016/j.exer.2016.09.002. Epub 2016 Sep 9.


The CXCR4 antagonist plerixafor enhances the effect of rituximab in diffuse large B-cell lymphoma cell lines.

Reinholdt L, Laursen MB, Schmitz A, Bødker JS, Jakobsen LH, Bøgsted M, Johnsen HE, Dybkær K.

Biomark Res. 2016 Jun 14;4:12. doi: 10.1186/s40364-016-0067-2. eCollection 2016.


Characterization of memory B cells from thymus and its impact for DLBCL classification.

Bergkvist KS, Nørgaard MA, Bøgsted M, Schmitz A, Nyegaard M, Gaihede M, Bæch J, Grønholdt ML, Jensen FS, Johansen P, Urup T, El-Galaly TC, Madsen J, Bødker JS, Dybkær K, Johnsen HE.

Exp Hematol. 2016 Oct;44(10):982-990.e11. doi: 10.1016/j.exphem.2016.06.001. Epub 2016 Jun 11.


miR-155 as a Biomarker in B-Cell Malignancies.

Due H, Svendsen P, Bødker JS, Schmitz A, Bøgsted M, Johnsen HE, El-Galaly TC, Roug AS, Dybkær K.

Biomed Res Int. 2016;2016:9513037. doi: 10.1155/2016/9513037. Epub 2016 May 16. Review.


Incidence of venous thromboembolism in patients with diffuse large B-cell lymphoma.

Borg IH, Bendtsen MD, Bøgsted M, Madsen J, Severinsen MT.

Leuk Lymphoma. 2016 Dec;57(12):2771-2776. Epub 2016 Jun 7.


Multiplex polymerase chain reaction-based prognostic models in diffuse large B-cell lymphoma patients treated with R-CHOP.

Green TM, Jensen AK, Holst R, Falgreen S, Bøgsted M, de Stricker K, Plesner T, Mourits-Andersen T, Frederiksen M, Johnsen HE, Pedersen LM, Møller MB.

Br J Haematol. 2016 Sep;174(6):876-86. doi: 10.1111/bjh.14138. Epub 2016 May 16.


Abnormal IGF-Binding Protein Profile in the Bone Marrow of Multiple Myeloma Patients.

Bieghs L, Brohus M, Kristensen IB, Abildgaard N, Bøgsted M, Johnsen HE, Conover CA, De Bruyne E, Vanderkerken K, Overgaard MT, Nyegaard M.

PLoS One. 2016 Apr 25;11(4):e0154256. doi: 10.1371/journal.pone.0154256. eCollection 2016.


Unaccounted uncertainty from qPCR efficiency estimates entails uncontrolled false positive rates.

Bilgrau AE, Falgreen S, Petersen A, Kjeldsen MK, Bødker JS, Johnsen HE, Dybkær K, Bøgsted M.

BMC Bioinformatics. 2016 Apr 11;17:159. doi: 10.1186/s12859-016-0997-6.


Blood on the tracks - toward precision medicine.

Johnsen HE, El-Galaly TC, Dybkær K, Bøgsted M.

Leuk Lymphoma. 2016 Aug;57(8):1753-4. doi: 10.3109/10428194.2016.1154962. Epub 2016 Mar 21. No abstract available.


Alternative pre-mRNA splicing leads to potential biomarkers in diffuse large B-cell lymphoma - a systematic review.

Østergaard Poulsen M, Krogh Jørgensen L, Sørensen S, Falgreen S, Støve Bødker JS, Bach Laursen M, Schmitz A, Johnsen HE, Dybkær K, Bøgsted M.

Dan Med J. 2016 Mar;63(3). pii: A5206. Review.


Little value of surveillance magnetic resonance imaging for primary CNS lymphomas in first remission: results from a Danish Multicentre Study.

Mylam KJ, Michaelsen TY, Hutchings M, Jacobsen Pulczynski E, Pedersen LM, Braendstrup P, Gade IL, Eberlein TR, Gang AO, Bøgsted M, Brown PN, El-Galaly TC.

Br J Haematol. 2017 Feb;176(4):671-673. doi: 10.1111/bjh.13988. Epub 2016 Feb 23. No abstract available.


High miR-34a expression improves response to doxorubicin in diffuse large B-cell lymphoma.

Marques SC, Ranjbar B, Laursen MB, Falgreen S, Bilgrau AE, Bødker JS, Jørgensen LK, Primo MN, Schmitz A, Ettrup MS, Johnsen HE, Bøgsted M, Mikkelsen JG, Dybkær K.

Exp Hematol. 2016 Apr;44(4):238-46.e2. doi: 10.1016/j.exphem.2015.12.007. Epub 2016 Feb 17.


No survival benefit associated with routine surveillance imaging for Hodgkin lymphoma in first remission: a Danish-Swedish population-based observational study.

Jakobsen LH, Hutchings M, de Nully Brown P, Linderoth J, Mylam KJ, Molin D, Johnsen HE, Bøgsted M, Jerkeman M, El-Galaly TC.

Br J Haematol. 2016 Apr;173(2):236-44. doi: 10.1111/bjh.13943. Epub 2016 Feb 5.


Bone Marrow Aspiration: A Randomized Controlled Trial Assessing the Quality of Bone Marrow Specimens Using Slow and Rapid Aspiration Techniques and Evaluating Pain Intensity.

Grønkjær M, Hasselgren CF, Østergaard AS, Johansen P, Korup J, Bøgsted M, Bilgrau AE, Jensen P.

Acta Haematol. 2016;135(2):81-7. doi: 10.1159/000438480. Epub 2015 Oct 28.


Routine Imaging for Diffuse Large B-Cell Lymphoma in First Complete Remission Does Not Improve Post-Treatment Survival: A Danish-Swedish Population-Based Study.

El-Galaly TC, Jakobsen LH, Hutchings M, de Nully Brown P, Nilsson-Ehle H, Székely E, Mylam KJ, Hjalmar V, Johnsen HE, Bøgsted M, Jerkeman M.

J Clin Oncol. 2015 Dec 1;33(34):3993-8. doi: 10.1200/JCO.2015.62.0229. Epub 2015 Oct 5.


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