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Best matches for Böttcher-Friebertshäuser E[au]:

The hemagglutinin: a determinant of pathogenicity. Böttcher-Friebertshäuser E et al. Curr Top Microbiol Immunol. (2014)

Optimization of Substrate-Analogue Furin Inhibitors. Ivanova T et al. ChemMedChem. (2017)

Activation of influenza viruses by proteases from host cells and bacteria in the human airway epithelium. Böttcher-Friebertshäuser E et al. Pathog Dis. (2013)

Search results

Items: 21

1.

TMPRSS2 is the major activating protease of influenza A virus in primary human airway cells and influenza B virus in human type II pneumocytes.

Limburg H, Harbig A, Bestle D, Stein DA, Moulton HM, Jaeger J, Janga H, Hardes K, Koepke J, Schulte L, Koczulla AR, Schmeck B, Klenk HD, Böttcher-Friebertshäuser E.

J Virol. 2019 Aug 7. pii: JVI.00649-19. doi: 10.1128/JVI.00649-19. [Epub ahead of print]

PMID:
31391268
2.

Mouse genetic background impacts susceptibility to hyperoxia-driven perturbations to lung maturation.

Tiono J, Surate Solaligue DE, Mižíková I, Nardiello C, Vadász I, Böttcher-Friebertshäuser E, Ehrhardt H, Herold S, Seeger W, Morty RE.

Pediatr Pulmonol. 2019 Jul;54(7):1060-1077. doi: 10.1002/ppul.24304. Epub 2019 Mar 7.

PMID:
30848059
3.

Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin.

Van Lam van T, Ivanova T, Hardes K, Heindl MR, Morty RE, Böttcher-Friebertshäuser E, Lindberg I, Than ME, Dahms SO, Steinmetzer T.

ChemMedChem. 2019 Mar 22;14(6):673-685. doi: 10.1002/cmdc.201800807. Epub 2019 Feb 20.

PMID:
30680958
4.

Resident alveolar macrophages are master regulators of arrested alveolarization in experimental bronchopulmonary dysplasia.

Kalymbetova TV, Selvakumar B, Rodríguez-Castillo JA, Gunjak M, Malainou C, Heindl MR, Moiseenko A, Chao CM, Vadász I, Mayer K, Lohmeyer J, Bellusci S, Böttcher-Friebertshäuser E, Seeger W, Herold S, Morty RE.

J Pathol. 2018 Jun;245(2):153-159. doi: 10.1002/path.5076. Epub 2018 Apr 18.

PMID:
29574785
5.

Optimization of Substrate-Analogue Furin Inhibitors.

Ivanova T, Hardes K, Kallis S, Dahms SO, Than ME, Künzel S, Böttcher-Friebertshäuser E, Lindberg I, Jiao GS, Bartenschlager R, Steinmetzer T.

ChemMedChem. 2017 Dec 7;12(23):1953-1968. doi: 10.1002/cmdc.201700596. Epub 2017 Nov 16.

PMID:
29059503
6.

Influenza virus activating host proteases: Identification, localization and inhibitors as potential therapeutics.

Garten W, Braden C, Arendt A, Peitsch C, Baron J, Lu Y, Pawletko K, Hardes K, Steinmetzer T, Böttcher-Friebertshäuser E.

Eur J Cell Biol. 2015 Jul-Sep;94(7-9):375-83. doi: 10.1016/j.ejcb.2015.05.013. Epub 2015 Jun 1.

PMID:
26095298
7.

Peptidomimetic furin inhibitor MI-701 in combination with oseltamivir and ribavirin efficiently blocks propagation of highly pathogenic avian influenza viruses and delays high level oseltamivir resistance in MDCK cells.

Lu Y, Hardes K, Dahms SO, Böttcher-Friebertshäuser E, Steinmetzer T, Than ME, Klenk HD, Garten W.

Antiviral Res. 2015 Aug;120:89-100. doi: 10.1016/j.antiviral.2015.05.006. Epub 2015 May 26.

PMID:
26022200
8.

The hemagglutinin: a determinant of pathogenicity.

Böttcher-Friebertshäuser E, Garten W, Matrosovich M, Klenk HD.

Curr Top Microbiol Immunol. 2014;385:3-34. doi: 10.1007/82_2014_384. Review.

PMID:
25031010
9.

TMPRSS2 is a host factor that is essential for pneumotropism and pathogenicity of H7N9 influenza A virus in mice.

Tarnow C, Engels G, Arendt A, Schwalm F, Sediri H, Preuss A, Nelson PS, Garten W, Klenk HD, Gabriel G, Böttcher-Friebertshäuser E.

J Virol. 2014 May;88(9):4744-51. doi: 10.1128/JVI.03799-13. Epub 2014 Feb 12.

10.

Activation of influenza A viruses by host proteases from swine airway epithelium.

Peitsch C, Klenk HD, Garten W, Böttcher-Friebertshäuser E.

J Virol. 2014 Jan;88(1):282-91. doi: 10.1128/JVI.01635-13. Epub 2013 Oct 23.

11.

Activation of influenza viruses by proteases from host cells and bacteria in the human airway epithelium.

Böttcher-Friebertshäuser E, Klenk HD, Garten W.

Pathog Dis. 2013 Nov;69(2):87-100. doi: 10.1111/2049-632X.12053. Epub 2013 Jul 2. Review.

PMID:
23821437
12.

Soluble polysialylated NCAM: a novel player of the innate immune system in the lung.

Ulm C, Saffarzadeh M, Mahavadi P, Müller S, Prem G, Saboor F, Simon P, Middendorff R, Geyer H, Henneke I, Bayer N, Rinné S, Lütteke T, Böttcher-Friebertshäuser E, Gerardy-Schahn R, Schwarzer D, Mühlenhoff M, Preissner KT, Günther A, Geyer R, Galuska SP.

Cell Mol Life Sci. 2013 Oct;70(19):3695-708. doi: 10.1007/s00018-013-1342-0. Epub 2013 Apr 26.

PMID:
23619613
13.

Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation.

Meyer D, Sielaff F, Hammami M, Böttcher-Friebertshäuser E, Garten W, Steinmetzer T.

Biochem J. 2013 Jun 1;452(2):331-43. doi: 10.1042/BJ20130101.

PMID:
23527573
14.

Matriptase, HAT, and TMPRSS2 activate the hemagglutinin of H9N2 influenza A viruses.

Baron J, Tarnow C, Mayoli-Nüssle D, Schilling E, Meyer D, Hammami M, Schwalm F, Steinmetzer T, Guan Y, Garten W, Klenk HD, Böttcher-Friebertshäuser E.

J Virol. 2013 Feb;87(3):1811-20. doi: 10.1128/JVI.02320-12. Epub 2012 Nov 28.

15.

Hemagglutinin activating host cell proteases provide promising drug targets for the treatment of influenza A and B virus infections.

Böttcher-Friebertshäuser E, Lu Y, Meyer D, Sielaff F, Steinmetzer T, Klenk HD, Garten W.

Vaccine. 2012 Dec 7;30(51):7374-80. doi: 10.1016/j.vaccine.2012.10.001. Epub 2012 Oct 13.

PMID:
23072892
16.

The production and development of H7 Influenza virus pseudotypes for the study of humoral responses against avian viruses.

Molesti E, Cattoli G, Ferrara F, Böttcher-Friebertshäuser E, Terregino C, Temperton N.

J Mol Genet Med. 2012;7:315-20. Epub 2013 Feb 19.

17.

The human Transmembrane Protease Serine 2 is necessary for the production of Group 2 influenza A virus pseudotypes.

Ferrara F, Molesti E, Böttcher-Friebertshäuser E, Cattoli G, Corti D, Scott SD, Temperton NJ.

J Mol Genet Med. 2012;7:309-14. Epub 2013 Feb 20.

18.

The use of equine influenza pseudotypes for serological screening.

Scott S, Molesti E, Temperton N, Ferrara F, Böttcher-Friebertshäuser E, Daly J.

J Mol Genet Med. 2012;6:304-8. Epub 2012 Dec 31.

19.

Development of substrate analogue inhibitors for the human airway trypsin-like protease HAT.

Sielaff F, Böttcher-Friebertshäuser E, Meyer D, Saupe SM, Volk IM, Garten W, Steinmetzer T.

Bioorg Med Chem Lett. 2011 Aug 15;21(16):4860-4. doi: 10.1016/j.bmcl.2011.06.033. Epub 2011 Jun 21.

PMID:
21741839
20.

Inhibition of influenza virus infection in human airway cell cultures by an antisense peptide-conjugated morpholino oligomer targeting the hemagglutinin-activating protease TMPRSS2.

Böttcher-Friebertshäuser E, Stein DA, Klenk HD, Garten W.

J Virol. 2011 Feb;85(4):1554-62. doi: 10.1128/JVI.01294-10. Epub 2010 Dec 1.

21.

Cleavage of influenza virus hemagglutinin by airway proteases TMPRSS2 and HAT differs in subcellular localization and susceptibility to protease inhibitors.

Böttcher-Friebertshäuser E, Freuer C, Sielaff F, Schmidt S, Eickmann M, Uhlendorff J, Steinmetzer T, Klenk HD, Garten W.

J Virol. 2010 Jun;84(11):5605-14. doi: 10.1128/JVI.00140-10. Epub 2010 Mar 17.

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