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Items: 1 to 50 of 109

1.

Profilin 1 Negatively Regulates Osteoclast Migration in Postnatal Skeletal Growth, Remodeling, and Homeostasis in Mice.

Shirakawa J, Kajikawa S, Böttcher RT, Costell M, Izu Y, Hayata T, Noda M, Ezura Y.

JBMR Plus. 2019 Jan 17;3(6):e10130. doi: 10.1002/jbm4.10130. eCollection 2019 Jun.

2.

Functional Network Analysis Reveals the Relevance of SKIIP in the Regulation of Alternative Splicing by p38 SAPK.

Carbonell C, Ulsamer A, Vivori C, Papasaikas P, Böttcher R, Joaquin M, Miñana B, Tejedor JR, de Nadal E, Valcárcel J, Posas F.

Cell Rep. 2019 Apr 16;27(3):847-859.e6. doi: 10.1016/j.celrep.2019.03.060.

3.

The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins.

Blasco-Moreno B, de Campos-Mata L, Böttcher R, García-Martínez J, Jungfleisch J, Nedialkova DD, Chattopadhyay S, Gas ME, Oliva B, Pérez-Ortín JE, Leidel SA, Choder M, Díez J.

Nat Commun. 2019 Mar 21;10(1):1298. doi: 10.1038/s41467-019-09199-6.

4.

Rapid reversible changes in compartments and local chromatin organization revealed by hyperosmotic shock.

Amat R, Böttcher R, Le Dily F, Vidal E, Quilez J, Cuartero Y, Beato M, de Nadal E, Posas F.

Genome Res. 2019 Jan;29(1):18-28. doi: 10.1101/gr.238527.118. Epub 2018 Dec 6.

5.

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

Tseng HY, Samarelli AV, Kammerer P, Scholze S, Ziegler T, Immler R, Zent R, Sperandio M, Sanders CR, Fässler R, Böttcher RT.

J Cell Sci. 2018 Nov 21;131(22). pii: jcs218214. doi: 10.1242/jcs.218214.

6.

On the incorporation of iron into hexagonal barium titanate: I. electron paramagnetic resonance (EPR) study.

Böttcher R, Langhammer HT, Kücker S, Eisenschmidt C, Ebbinghaus SG.

J Phys Condens Matter. 2018 Oct 24;30(42):425701. doi: 10.1088/1361-648X/aadea8. Epub 2018 Sep 4.

PMID:
30178757
7.

FAK auto-phosphorylation site tyrosine 397 is required for development but dispensable for normal skin homeostasis.

Heim JB, McDonald CA, Wyles SP, Sominidi-Damodaran S, Squirewell EJ, Li M, Motsonelidze C, Böttcher RT, van Deursen J, Meves A.

PLoS One. 2018 Jul 12;13(7):e0200558. doi: 10.1371/journal.pone.0200558. eCollection 2018.

8.

Epithelial-Mesenchymal Transition in Human Prostate Cancer Demonstrates Enhanced Immune Evasion Marked by IDO1 Expression.

Kolijn K, Verhoef EI, Smid M, Böttcher R, Jenster GW, Debets R, van Leenders GJLH.

Cancer Res. 2018 Aug 15;78(16):4671-4679. doi: 10.1158/0008-5472.CAN-17-3752. Epub 2018 Jun 19.

9.

[Traumatic lesions of the brachial plexus : Clinical symptoms, diagnostics and treatment].

Schnick U, Dähne F, Tittel A, Vogel K, Vogel A, Eisenschenk A, Ekkernkamp A, Böttcher R.

Unfallchirurg. 2018 Jun;121(6):483-496. doi: 10.1007/s00113-018-0506-7. German.

PMID:
29736764
10.

Cribriform and intraductal prostate cancer are associated with increased genomic instability and distinct genomic alterations.

Böttcher R, Kweldam CF, Livingstone J, Lalonde E, Yamaguchi TN, Huang V, Yousif F, Fraser M, Bristow RG, van der Kwast T, Boutros PC, Jenster G, van Leenders GJLH.

BMC Cancer. 2018 Jan 2;18(1):8. doi: 10.1186/s12885-017-3976-z.

11.

Migrating Platelets Are Mechano-scavengers that Collect and Bundle Bacteria.

Gaertner F, Ahmad Z, Rosenberger G, Fan S, Nicolai L, Busch B, Yavuz G, Luckner M, Ishikawa-Ankerhold H, Hennel R, Benechet A, Lorenz M, Chandraratne S, Schubert I, Helmer S, Striednig B, Stark K, Janko M, Böttcher RT, Verschoor A, Leon C, Gachet C, Gudermann T, Mederos Y Schnitzler M, Pincus Z, Iannacone M, Haas R, Wanner G, Lauber K, Sixt M, Massberg S.

Cell. 2017 Nov 30;171(6):1368-1382.e23. doi: 10.1016/j.cell.2017.11.001.

12.

Regulation of transcription elongation in response to osmostress.

Silva A, Cavero S, Begley V, Solé C, Böttcher R, Chávez S, Posas F, de Nadal E.

PLoS Genet. 2017 Nov 20;13(11):e1007090. doi: 10.1371/journal.pgen.1007090. eCollection 2017 Nov.

13.

Low density lipoprotein receptor-related protein 1 couples β1 integrin activation to degradation.

Wujak L, Böttcher RT, Pak O, Frey H, El Agha E, Chen Y, Schmitt S, Bellusci S, Schaefer L, Weissmann N, Fässler R, Wygrecka M.

Cell Mol Life Sci. 2018 May;75(9):1671-1685. doi: 10.1007/s00018-017-2707-6. Epub 2017 Nov 7.

PMID:
29116364
14.

Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD/Dcr-2 complex in RNA interference.

Tants JN, Fesser S, Kern T, Stehle R, Geerlof A, Wunderlich C, Juen M, Hartlmüller C, Böttcher R, Kunzelmann S, Lange O, Kreutz C, Förstemann K, Sattler M.

Nucleic Acids Res. 2017 Dec 1;45(21):12536-12550. doi: 10.1093/nar/gkx886.

15.

Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading.

Böttcher RT, Veelders M, Rombaut P, Faix J, Theodosiou M, Stradal TE, Rottner K, Zent R, Herzog F, Fässler R.

J Cell Biol. 2017 Nov 6;216(11):3785-3798. doi: 10.1083/jcb.201701176. Epub 2017 Sep 14.

16.

A forceful connection: mechanoregulation of oncogenic YAP.

Böttcher RT, Sun Z, Fässler R.

EMBO J. 2017 Sep 1;36(17):2467-2469. doi: 10.15252/embj.201797527. Epub 2017 Jul 19. No abstract available.

17.

A balanced level of profilin-1 promotes stemness and tumor-initiating potential of breast cancer cells.

Jiang C, Ding Z, Joy M, Chakraborty S, Kim SH, Bottcher R, Condeelis J, Singh S, Roy P.

Cell Cycle. 2017;16(24):2366-2373. doi: 10.1080/15384101.2017.1346759.

18.

Pharmacological intervention of MKL/SRF signaling by CCG-1423 impedes endothelial cell migration and angiogenesis.

Gau D, Veon W, Capasso TL, Bottcher R, Shroff S, Roman BL, Roy P.

Angiogenesis. 2017 Nov;20(4):663-672. doi: 10.1007/s10456-017-9560-y. Epub 2017 Jun 21.

19.

Splicing stimulates siRNA formation at Drosophila DNA double-strand breaks.

Merk K, Breinig M, Böttcher R, Krebs S, Blum H, Boutros M, Förstemann K.

PLoS Genet. 2017 Jun 19;13(6):e1006861. doi: 10.1371/journal.pgen.1006861. eCollection 2017 Jun.

20.

Coronin 1A, a novel player in integrin biology, controls neutrophil trafficking in innate immunity.

Pick R, Begandt D, Stocker TJ, Salvermoser M, Thome S, Böttcher RT, Montanez E, Harrison U, Forné I, Khandoga AG, Coletti R, Weckbach LT, Brechtefeld D, Haas R, Imhof A, Massberg S, Sperandio M, Walzog B.

Blood. 2017 Aug 17;130(7):847-858. doi: 10.1182/blood-2016-11-749622. Epub 2017 Jun 14.

PMID:
28615221
21.

Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix.

Heim JB, Squirewell EJ, Neu A, Zocher G, Sominidi-Damodaran S, Wyles SP, Nikolova E, Behrendt N, Saunte DM, Lock-Andersen J, Gaonkar KS, Yan H, Sarkaria JN, Krendel M, van Deursen J, Sprangers R, Stehle T, Böttcher RT, Lee JH, Ordog T, Meves A.

Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3933-3938. doi: 10.1073/pnas.1614894114. Epub 2017 Mar 27.

22.

Profilin1 is expressed in osteocytes and regulates cell shape and migration.

Lin W, Izu Y, Smriti A, Kawasaki M, Pawaputanon C, Böttcher RT, Costell M, Moriyama K, Noda M, Ezura Y.

J Cell Physiol. 2018 Jan;233(1):259-268. doi: 10.1002/jcp.25872. Epub 2017 May 3.

PMID:
28233307
23.

A mononucleotide repeat in PRRT2 is an important, frequent target of mismatch repair deficiency in cancer.

Alves IT, Cano D, Böttcher R, van der Korput H, Dinjens W, Jenster G, Trapman J.

Oncotarget. 2017 Jan 24;8(4):6043-6056. doi: 10.18632/oncotarget.13464.

24.

PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis.

Mana G, Clapero F, Panieri E, Panero V, Böttcher RT, Tseng HY, Saltarin F, Astanina E, Wolanska KI, Morgan MR, Humphries MJ, Santoro MM, Serini G, Valdembri D.

Nat Commun. 2016 Nov 23;7:13546. doi: 10.1038/ncomms13546.

25.

[Pedicled vascularized bone graft for scaphoid reconstruction after Zaidemberg].

Schacher B, Böttcher R, Vogel A, Asmus A, Kim S, Eisenschenk A, Eichenauer F.

Orthopade. 2016 Nov;45(11):974-984. Review. German.

PMID:
27628593
26.

Gene-expression analysis of gleason grade 3 tumor glands embedded in low- and high-risk prostate cancer.

Hoogland AM, Böttcher R, Verhoef E, Jenster G, van Leenders GJ.

Oncotarget. 2016 Jun 21;7(25):37846-37856. doi: 10.18632/oncotarget.9344.

27.

Evolution of protein phosphorylation across 18 fungal species.

Studer RA, Rodriguez-Mias RA, Haas KM, Hsu JI, Viéitez C, Solé C, Swaney DL, Stanford LB, Liachko I, Böttcher R, Dunham MJ, de Nadal E, Posas F, Beltrao P, Villén J.

Science. 2016 Oct 14;354(6309):229-232.

PMID:
27738172
28.

Human PDE4D isoform composition is deregulated in primary prostate cancer and indicative for disease progression and development of distant metastases.

Böttcher R, Dulla K, van Strijp D, Dits N, Verhoef EI, Baillie GS, van Leenders GJ, Houslay MD, Jenster G, Hoffmann R.

Oncotarget. 2016 Oct 25;7(43):70669-70684. doi: 10.18632/oncotarget.12204.

29.

Loss of SLCO1B3 drives taxane resistance in prostate cancer.

de Morrée ES, Böttcher R, van Soest RJ, Aghai A, de Ridder CM, Gibson AA, Mathijssen RH, Burger H, Wiemer EA, Sparreboom A, de Wit R, van Weerden WM.

Br J Cancer. 2016 Sep 6;115(6):674-81. doi: 10.1038/bjc.2016.251. Epub 2016 Aug 18.

30.

Homology directed repair is unaffected by the absence of siRNAs in Drosophila melanogaster.

Schmidts I, Böttcher R, Mirkovic-Hösle M, Förstemann K.

Nucleic Acids Res. 2016 Sep 30;44(17):8261-71. doi: 10.1093/nar/gkw570. Epub 2016 Jun 27.

31.

Secreted Phospholipases A2 Are Intestinal Stem Cell Niche Factors with Distinct Roles in Homeostasis, Inflammation, and Cancer.

Schewe M, Franken PF, Sacchetti A, Schmitt M, Joosten R, Böttcher R, van Royen ME, Jeammet L, Payré C, Scott PM, Webb NR, Gelb M, Cormier RT, Lambeau G, Fodde R.

Cell Stem Cell. 2016 Jul 7;19(1):38-51. doi: 10.1016/j.stem.2016.05.023. Epub 2016 Jun 9.

32.

A Comprehensive Toolbox for Genome Editing in Cultured Drosophila melanogaster Cells.

Kunzelmann S, Böttcher R, Schmidts I, Förstemann K.

G3 (Bethesda). 2016 Jun 1;6(6):1777-85. doi: 10.1534/g3.116.028241.

33.

Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin.

Theodosiou M, Widmaier M, Böttcher RT, Rognoni E, Veelders M, Bharadwaj M, Lambacher A, Austen K, Müller DJ, Zent R, Fässler R.

Elife. 2016 Jan 27;5:e10130. doi: 10.7554/eLife.10130.

34.

Identification of Patients with Recurrent Glioblastoma Who May Benefit from Combined Bevacizumab and CCNU Therapy: A Report from the BELOB Trial.

Erdem-Eraslan L, van den Bent MJ, Hoogstrate Y, Naz-Khan H, Stubbs A, van der Spek P, Böttcher R, Gao Y, de Wit M, Taal W, Oosterkamp HM, Walenkamp A, Beerepoot LV, Hanse MC, Buter J, Honkoop AH, van der Holt B, Vernhout RM, Sillevis Smitt PA, Kros JM, French PJ.

Cancer Res. 2016 Feb 1;76(3):525-34. doi: 10.1158/0008-5472.CAN-15-0776. Epub 2016 Jan 13.

35.

Role of β1 integrins and bacterial adhesins for Yop injection into leukocytes in Yersinia enterocolitica systemic mouse infection.

Deuschle E, Keller B, Siegfried A, Manncke B, Spaeth T, Köberle M, Drechsler-Hake D, Reber J, Böttcher RT, Autenrieth SE, Autenrieth IB, Bohn E, Schütz M.

Int J Med Microbiol. 2016 Feb;306(2):77-88. doi: 10.1016/j.ijmm.2015.12.001. Epub 2015 Dec 15.

PMID:
26718660
36.

FuMa: reporting overlap in RNA-seq detected fusion genes.

Hoogstrate Y, Böttcher R, Hiltemann S, van der Spek PJ, Jenster G, Stubbs AP.

Bioinformatics. 2016 Apr 15;32(8):1226-8. doi: 10.1093/bioinformatics/btv721. Epub 2015 Dec 10.

PMID:
26656567
37.

Human phosphodiesterase 4D7 (PDE4D7) expression is increased in TMPRSS2-ERG-positive primary prostate cancer and independently adds to a reduced risk of post-surgical disease progression.

Böttcher R, Henderson DJ, Dulla K, van Strijp D, Waanders LF, Tevz G, Lehman ML, Merkle D, van Leenders GJ, Baillie GS, Jenster G, Houslay MD, Hoffmann R.

Br J Cancer. 2015 Nov 17;113(10):1502-11. doi: 10.1038/bjc.2015.335.

38.

Defect properties of cobalt-doped hexagonal barium titanate ceramics.

Langhammer HT, Böttcher R, Müller T, Walther T, Ebbinghaus SG.

J Phys Condens Matter. 2015 Jul 29;27(29):295901. doi: 10.1088/0953-8984/27/29/295901. Epub 2015 Jul 8.

PMID:
26154400
39.

Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt.

Yazlovitskaya EM, Tseng HY, Viquez O, Tu T, Mernaugh G, McKee KK, Riggins K, Quaranta V, Pathak A, Carter BD, Yurchenco P, Sonnenberg A, Böttcher RT, Pozzi A, Zent R.

Mol Biol Cell. 2015 May 15;26(10):1857-74. doi: 10.1091/mbc.E14-07-1203. Epub 2015 Mar 25.

40.

Novel long non-coding RNAs are specific diagnostic and prognostic markers for prostate cancer.

Böttcher R, Hoogland AM, Dits N, Verhoef EI, Kweldam C, Waranecki P, Bangma CH, van Leenders GJ, Jenster G.

Oncotarget. 2015 Feb 28;6(6):4036-50.

41.

Yersinia enterocolitica exploits different pathways to accomplish adhesion and toxin injection into host cells.

Keller B, Mühlenkamp M, Deuschle E, Siegfried A, Mössner S, Schade J, Griesinger T, Katava N, Braunsdorf C, Fehrenbacher B, Jiménez-Soto LF, Schaller M, Haas R, Genth H, Retta SF, Meyer H, Böttcher RT, Zent R, Schütz M, Autenrieth IB, Bohn E.

Cell Microbiol. 2015 Aug;17(8):1179-204. doi: 10.1111/cmi.12429. Epub 2015 Mar 20.

PMID:
25678064
42.

Membrane tension drives ligand-independent integrin signaling.

Böttcher RT, Fässler R.

EMBO J. 2014 Nov 3;33(21):2439-41. doi: 10.15252/embj.201489886. Epub 2014 Sep 17. No abstract available.

43.

Sorting nexin 31 binds multiple β integrin cytoplasmic domains and regulates β1 integrin surface levels and stability.

Tseng HY, Thorausch N, Ziegler T, Meves A, Fässler R, Böttcher RT.

J Mol Biol. 2014 Sep 9;426(18):3180-3194. doi: 10.1016/j.jmb.2014.07.003. Epub 2014 Jul 11.

PMID:
25020227
44.

(55)Mn pulsed ENDOR spectroscopy of Mn(2+) ions in ZnO thin films and single crystal.

Böttcher R, Pöppl A, Lorenz M, Friedländer S, Spemann D, Grundmann M.

J Magn Reson. 2014 Aug;245:79-86. doi: 10.1016/j.jmr.2014.05.012. Epub 2014 Jun 13.

PMID:
24993844
45.

Efficient chromosomal gene modification with CRISPR/cas9 and PCR-based homologous recombination donors in cultured Drosophila cells.

Böttcher R, Hollmann M, Merk K, Nitschko V, Obermaier C, Philippou-Massier J, Wieland I, Gaul U, Förstemann K.

Nucleic Acids Res. 2014 Jun;42(11):e89. doi: 10.1093/nar/gku289. Epub 2014 Apr 19.

46.

Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation.

Rognoni E, Widmaier M, Jakobson M, Ruppert R, Ussar S, Katsougkri D, Böttcher RT, Lai-Cheong JE, Rifkin DB, McGrath JA, Fässler R.

Nat Med. 2014 Apr;20(4):350-9. doi: 10.1038/nm.3490. Epub 2014 Mar 30.

47.

Profilin 1 is required for peripheral nervous system myelination.

Montani L, Buerki-Thurnherr T, de Faria JP, Pereira JA, Dias NG, Fernandes R, Gonçalves AF, Braun A, Benninger Y, Böttcher RT, Costell M, Nave KA, Franklin RJ, Meijer D, Suter U, Relvas JB.

Development. 2014 Apr;141(7):1553-61. doi: 10.1242/dev.101840. Epub 2014 Mar 5.

48.

Next-generation sequencing reveals novel rare fusion events with functional implication in prostate cancer.

Teles Alves I, Hartjes T, McClellan E, Hiltemann S, Böttcher R, Dits N, Temanni MR, Janssen B, van Workum W, van der Spek P, Stubbs A, de Klein A, Eussen B, Trapman J, Jenster G.

Oncogene. 2015 Jan 29;34(5):568-77. doi: 10.1038/onc.2013.591. Epub 2014 Feb 3.

PMID:
24488012
49.

Profilin 1 is essential for retention and metabolism of mouse hematopoietic stem cells in bone marrow.

Zheng J, Lu Z, Kocabas F, Böttcher RT, Costell M, Kang X, Liu X, Deberardinis RJ, Wang Q, Chen GQ, Sadek H, Zhang CC.

Blood. 2014 Feb 13;123(7):992-1001. doi: 10.1182/blood-2013-04-498469. Epub 2014 Jan 2.

50.

Long noncoding RNA in prostate, bladder, and kidney cancer.

Martens-Uzunova ES, Böttcher R, Croce CM, Jenster G, Visakorpi T, Calin GA.

Eur Urol. 2014 Jun;65(6):1140-51. doi: 10.1016/j.eururo.2013.12.003. Epub 2013 Dec 14. Review.

PMID:
24373479

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