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Items: 17

1.

N-terminal pyroglutamate formation in CX3CL1 is essential for its full biologic activity.

Kehlen A, Haegele M, Böhme L, Cynis H, Hoffmann T, Demuth HU.

Biosci Rep. 2017 Aug 23;37(4). pii: BSR20170712. doi: 10.1042/BSR20170712. Print 2017 Aug 31.

2.

Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer's Disease-Studies on Relation to Effective Target Occupancy.

Hoffmann T, Meyer A, Heiser U, Kurat S, Böhme L, Kleinschmidt M, Bühring KU, Hutter-Paier B, Farcher M, Demuth HU, Lues I, Schilling S.

J Pharmacol Exp Ther. 2017 Jul;362(1):119-130. doi: 10.1124/jpet.117.240614. Epub 2017 Apr 26.

PMID:
28446518
3.

Structure-activity relationships of benzimidazole-based glutaminyl cyclase inhibitors featuring a heteroaryl scaffold.

Ramsbeck D, Buchholz M, Koch B, Böhme L, Hoffmann T, Demuth HU, Heiser U.

J Med Chem. 2013 Sep 12;56(17):6613-25. doi: 10.1021/jm4001709. Epub 2013 Aug 19.

PMID:
23886302
4.

Region-specific expression of vesicular glutamate and GABA transporters under various ischaemic conditions in mouse forebrain and retina.

Michalski D, Härtig W, Krügel K, Edwards RH, Böddener M, Böhme L, Pannicke T, Reichenbach A, Grosche A.

Neuroscience. 2013 Feb 12;231:328-44. doi: 10.1016/j.neuroscience.2012.11.046. Epub 2012 Dec 5.

PMID:
23219666
5.

Imbalanced oxidative stress causes chlamydial persistence during non-productive human herpes virus co-infection.

Prusty BK, Böhme L, Bergmann B, Siegl C, Krause E, Mehlitz A, Rudel T.

PLoS One. 2012;7(10):e47427. doi: 10.1371/journal.pone.0047427. Epub 2012 Oct 15.

6.

Influence of implantable hearing aids and neuroprosthesison music perception.

Rahne T, Böhme L, Götze G.

ScientificWorldJournal. 2012;2012:404590. doi: 10.1100/2012/404590. Epub 2012 May 3.

7.

HIF-1α is involved in mediating apoptosis resistance to Chlamydia trachomatis-infected cells.

Sharma M, Machuy N, Böhme L, Karunakaran K, Mäurer AP, Meyer TF, Rudel T.

Cell Microbiol. 2011 Oct;13(10):1573-85. doi: 10.1111/j.1462-5822.2011.01642.x. Epub 2011 Aug 8.

PMID:
21824245
8.

Timbre discrimination in cochlear implant users and normal hearing subjects using cross-faded synthetic tones.

Rahne T, Böhme L, Götze G.

J Neurosci Methods. 2011 Aug 15;199(2):290-5. doi: 10.1016/j.jneumeth.2011.05.022. Epub 2011 Jun 1.

PMID:
21664377
9.

Chlamydia trachomatis-infected host cells resist dsRNA-induced apoptosis.

Böhme L, Albrecht M, Riede O, Rudel T.

Cell Microbiol. 2010 Sep 1;12(9):1340-51. doi: 10.1111/j.1462-5822.2010.01473.x. Epub 2010 May 6.

PMID:
20482554
10.

Inhibitors for human glutaminyl cyclase by structure based design and bioisosteric replacement.

Buchholz M, Hamann A, Aust S, Brandt W, Böhme L, Hoffmann T, Schilling S, Demuth HU, Heiser U.

J Med Chem. 2009 Nov 26;52(22):7069-80. doi: 10.1021/jm900969p.

PMID:
19863057
11.

Host cell death machinery as a target for bacterial pathogens.

Böhme L, Rudel T.

Microbes Infect. 2009 Nov;11(13):1063-70. doi: 10.1016/j.micinf.2009.08.014. Epub 2009 Sep 4. Review.

PMID:
19733679
12.

cIAP-1 controls innate immunity to C. pneumoniae pulmonary infection.

Prakash H, Becker D, Böhme L, Albert L, Witzenrath M, Rosseau S, Meyer TF, Rudel T.

PLoS One. 2009 Aug 6;4(8):e6519. doi: 10.1371/journal.pone.0006519.

13.

Isoaspartate-containing amyloid precursor protein-derived peptides alter efficacy and specificity of potential beta-secretases.

Böhme L, Hoffmann T, Manhart S, Wolf R, Demuth HU.

Biol Chem. 2008 Aug;389(8):1055-66. doi: 10.1515/BC.2008.125.

PMID:
18979630
14.

Isoaspartate residues dramatically influence substrate recognition and turnover by proteases.

Böhme L, Bär JW, Hoffmann T, Manhart S, Ludwig HH, Rosche F, Demuth HU.

Biol Chem. 2008 Aug;389(8):1043-53. doi: 10.1515/BC.2008.123.

PMID:
18979629
15.

Reduced display of tumor necrosis factor receptor I at the host cell surface supports infection with Chlamydia trachomatis.

Paland N, Böhme L, Gurumurthy RK, Mäurer A, Szczepek AJ, Rudel T.

J Biol Chem. 2008 Mar 7;283(10):6438-48. doi: 10.1074/jbc.M708422200. Epub 2007 Dec 31.

16.

[Characterization of pyrimidine nucleotide conjugates synthezised in Lactobacillus viridescens in dependence on thiamine].

Böcker R, Bohme L, Kersten H, Kersten W.

Hoppe Seylers Z Physiol Chem. 1972 Oct;353(10):1504. German. No abstract available.

PMID:
4649771
17.

[Wrong diet increases risk for myocardial infarct].

Böhme L.

Z Allgemeinmed. 1971 Jun 10;47(16):864. German. No abstract available.

PMID:
5558938

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