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Items: 10


The Cell Wall Polymer Lipoteichoic Acid Becomes Nonessential in Staphylococcus aureus Cells Lacking the ClpX Chaperone.

Bæk KT, Bowman L, Millership C, Dupont Søgaard M, Kaever V, Siljamäki P, Savijoki K, Varmanen P, Nyman TA, Gründling A, Frees D.

MBio. 2016 Aug 9;7(4). pii: e01228-16. doi: 10.1128/mBio.01228-16.


Rifampin Resistance rpoB Alleles or Multicopy Thioredoxin/Thioredoxin Reductase Suppresses the Lethality of Disruption of the Global Stress Regulator spx in Staphylococcus aureus.

Villanueva M, Jousselin A, Baek KT, Prados J, Andrey DO, Renzoni A, Ingmer H, Frees D, Kelley WL.

J Bacteriol. 2016 Sep 9;198(19):2719-31. doi: 10.1128/JB.00261-16. Print 2016 Oct 1.


Stepwise decrease in daptomycin susceptibility in clinical Staphylococcus aureus isolates associated with an initial mutation in rpoB and a compensatory inactivation of the clpX gene.

Bæk KT, Thøgersen L, Mogenssen RG, Mellergaard M, Thomsen LE, Petersen A, Skov S, Cameron DR, Peleg AY, Frees D.

Antimicrob Agents Chemother. 2015 Nov;59(11):6983-91. doi: 10.1128/AAC.01303-15. Epub 2015 Aug 31.


β-Lactam resistance in methicillin-resistant Staphylococcus aureus USA300 is increased by inactivation of the ClpXP protease.

Bæk KT, Gründling A, Mogensen RG, Thøgersen L, Petersen A, Paulander W, Frees D.

Antimicrob Agents Chemother. 2014 Aug;58(8):4593-603. doi: 10.1128/AAC.02802-14. Epub 2014 May 27.


Genetic variation in the Staphylococcus aureus 8325 strain lineage revealed by whole-genome sequencing.

Bæk KT, Frees D, Renzoni A, Barras C, Rodriguez N, Manzano C, Kelley WL.

PLoS One. 2013 Sep 30;8(9):e77122. doi: 10.1371/journal.pone.0077122. eCollection 2013.


Antibiotic-mediated selection of quorum-sensing-negative Staphylococcus aureus.

Paulander W, Nissen Varming A, Bæk KT, Haaber J, Frees D, Ingmer H.

MBio. 2013 Jan 2;3(6):e00459-12. doi: 10.1128/mBio.00459-12.


Rapid paracellular transmigration of Campylobacter jejuni across polarized epithelial cells without affecting TER: role of proteolytic-active HtrA cleaving E-cadherin but not fibronectin.

Boehm M, Hoy B, Rohde M, Tegtmeyer N, Bæk KT, Oyarzabal OA, Brøndsted L, Wessler S, Backert S.

Gut Pathog. 2012 Apr 25;4(1):3. doi: 10.1186/1757-4749-4-3.


New insights into Staphylococcus aureus stress tolerance and virulence regulation from an analysis of the role of the ClpP protease in the strains Newman, COL, and SA564.

Frees D, Andersen JH, Hemmingsen L, Koskenniemi K, Bæk KT, Muhammed MK, Gudeta DD, Nyman TA, Sukura A, Varmanen P, Savijoki K.

J Proteome Res. 2012 Jan 1;11(1):95-108. doi: 10.1021/pr200956s. Epub 2011 Dec 12.


HtrA chaperone activity contributes to host cell binding in Campylobacter jejuni.

Bæk KT, Vegge CS, Brøndsted L.

Gut Pathog. 2011 Sep 22;3:13. doi: 10.1186/1757-4749-3-13.


Different contributions of HtrA protease and chaperone activities to Campylobacter jejuni stress tolerance and physiology.

Baek KT, Vegge CS, Skórko-Glonek J, Brøndsted L.

Appl Environ Microbiol. 2011 Jan;77(1):57-66. doi: 10.1128/AEM.01603-10. Epub 2010 Nov 12.

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