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Items: 41

1.

Quantitative analysis of the CD4+ T cell response to therapeutic antibodies in healthy donors using a novel T cell:PBMC assay.

Schultz HS, Reedtz-Runge SL, Bäckström BT, Lamberth K, Pedersen CR, Kvarnhammar AM; ABIRISK consortium.

PLoS One. 2017 May 31;12(5):e0178544. doi: 10.1371/journal.pone.0178544. eCollection 2017.

2.

A modified superantigen rescues Ly6G- CD11b+ blood monocyte suppressor function and suppresses antigen-specific inflammation in EAE.

Slaney CY, Toker A, Fraser JD, Harper JL, Bäckström BT.

Autoimmunity. 2013 Jun;46(4):269-78. doi: 10.3109/08916934.2013.767893.

PMID:
23374140
3.

Thymic gene transfer of myelin oligodendrocyte glycoprotein ameliorates the onset but not the progression of autoimmune demyelination.

Siatskas C, Seach N, Sun G, Emerson-Webber A, Silvain A, Toh BH, Alderuccio F, Bäckström BT, Boyd RL, Bernard CC.

Mol Ther. 2012 Jul;20(7):1349-59. doi: 10.1038/mt.2012.15. Epub 2012 Feb 21.

4.

Glatiramer acetate treatment directly targets CD11b(+)Ly6G(-) monocytes and enhances the suppression of autoreactive T cells in experimental autoimmune encephalomyelitis.

Toker A, Slaney CY, Bäckström BT, Harper JL.

Scand J Immunol. 2011 Sep;74(3):235-243. doi: 10.1111/j.1365-3083.2011.02575.x.

5.

Naïve blood monocytes suppress T-cell function. A possible mechanism for protection from autoimmunity.

Slaney CY, Toker A, La Flamme A, Bäckström BT, Harper JL.

Immunol Cell Biol. 2011 Jan;89(1):7-13. doi: 10.1038/icb.2010.110. Epub 2010 Nov 9.

PMID:
21060323
6.

Targeting antigen to MHC class II molecules promotes efficient cross-presentation and enhances immunotherapy.

Dickgreber N, Stoitzner P, Bai Y, Price KM, Farrand KJ, Manning K, Angel CE, Dunbar PR, Ronchese F, Fraser JD, Bäckström BT, Hermans IF.

J Immunol. 2009 Feb 1;182(3):1260-9.

7.

Transplantation of bone marrow transduced to express self-antigen establishes deletional tolerance and permanently remits autoimmune disease.

Chan J, Ban EJ, Chun KH, Wang S, Bäckström BT, Bernard CC, Toh BH, Alderuccio F.

J Immunol. 2008 Dec 1;181(11):7571-80.

8.

A chimeric TCR-beta chain confers increased susceptibility to EAE.

Petersen TR, Lata R, Spittle E, Bäckström BT.

Mol Immunol. 2007 Jul;44(14):3473-81. Epub 2007 May 3.

PMID:
17481734
9.

Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.

Korn T, Reddy J, Gao W, Bettelli E, Awasthi A, Petersen TR, Bäckström BT, Sobel RA, Wucherpfennig KW, Strom TB, Oukka M, Kuchroo VK.

Nat Med. 2007 Apr;13(4):423-31. Epub 2007 Mar 25.

10.
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Critical role of preproenkephalin in experimental autoimmune encephalomyelitis.

Weir C, McNeill A, Hook S, Harvie M, La Flamme AC, Le Gros G, Bäckström BT.

J Neuroimmunol. 2006 Oct;179(1-2):18-25. Epub 2006 Aug 9.

PMID:
16904193
13.

Fcgamma receptor-ligating complexes improve the course of experimental autoimmune encephalomyelitis by enhancing basal Th2 responses.

La Flamme AC, Harvie M, McNeill A, Goldsack L, Tierney JB, Bäckström BT.

Immunol Cell Biol. 2006 Dec;84(6):522-9. Epub 2006 Jul 20.

PMID:
16869936
15.

Peloruside A enhances apoptosis in H-ras-transformed cells and is cytotoxic to proliferating T cells.

Miller JH, Rouwé B, Gaitanos TN, Hood KA, Crume KP, Bäckström BT, La Flamme AC, Berridge MV, Northcote PT.

Apoptosis. 2004 Nov;9(6):785-96.

PMID:
15505421
16.

Schistosomiasis protects against multiple sclerosis.

La Flamme AC, Canagasabey K, Harvie M, Bäckström BT.

Mem Inst Oswaldo Cruz. 2004;99(5 Suppl 1):33-6. Epub 2004 Oct 13. Review.

17.

A simplified cytokine immunoassay using magnetic polymer particles.

McNeill A, Kastrup J, Bäckström BT.

Scand J Immunol. 2004 Sep;60(3):287-91.

18.

Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene.

Hultqvist M, Olofsson P, Holmberg J, Bäckström BT, Tordsson J, Holmdahl R.

Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12646-51. Epub 2004 Aug 13.

19.

A chimeric T cell receptor with super-signaling properties.

Petersen TR, Gülland S, Bettelli E, Kuchroo V, Palmer E, Bäckström BT.

Int Immunol. 2004 Jul;16(7):889-94. Epub 2004 May 17.

PMID:
15148288
20.

Flow cytometric quantitation of the protective efficacy of dendritic cell based vaccines in a human papillomavirus type 16 murine challenge model.

Heinemann L, Dillon S, Crawford A, Bäckström BT, Hibma MH.

J Virol Methods. 2004 Apr;117(1):9-18.

PMID:
15019255
21.

Characterization of MHC- and TCR-binding residues of the myelin oligodendrocyte glycoprotein 38-51 peptide.

Petersen TR, Bettelli E, Sidney J, Sette A, Kuchroo V, Bäckström BT.

Eur J Immunol. 2004 Jan;34(1):165-73.

22.

IL-5-deficient mice are susceptible to experimental autoimmune encephalomyelitis.

Weir C, Bernard CC, Bäckström BT.

Int Immunol. 2003 Nov;15(11):1283-9.

PMID:
14565926
23.
24.

Depletion of Langerhans cells in human papillomavirus type 16-infected skin is associated with E6-mediated down regulation of E-cadherin.

Matthews K, Leong CM, Baxter L, Inglis E, Yun K, Bäckström BT, Doorbar J, Hibma M.

J Virol. 2003 Aug;77(15):8378-85.

25.
26.

Induction of experimental autoimmune encephalomyelitis in the absence of c-Jun N-terminal kinase 2.

Nicolson K, Freland S, Weir C, Delahunt B, Flavell RA, Bäckström BT.

Int Immunol. 2002 Aug;14(8):849-56.

PMID:
12147621
27.

The novel cytotoxic sponge metabolite peloruside A, structurally similar to bryostatin-1, has unique bioactivity independent of protein kinase C.

Hood KA, Bäckström BT, West LM, Northcote PT, Berridge MV, Miller JH.

Anticancer Drug Des. 2001 Apr-Jun;16(2-3):155-66.

PMID:
11962513
28.

Experimental autoimmune encephalomyelitis induction in naive mice by dendritic cells presenting a self-peptide.

Weir CR, Nicolson K, Bäckström BT.

Immunol Cell Biol. 2002 Feb;80(1):14-20.

PMID:
11869358
29.

Importance of the T cell receptor alpha-chain transmembrane distal region for assembly with cognate subunits.

Shelton JG, Gülland S, Nicolson K, Kearse KP, Bäckström BT.

Mol Immunol. 2001 Aug;38(4):259-65.

PMID:
11566319
30.

Positive selection through a motif in the alphabeta T cell receptor.

Bäckström BT, Müller U, Hausmann B, Palmer E.

Science. 1998 Aug 7;281(5378):835-8.

31.
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T cell receptor alpha-chain tail is required for protein kinase C-mediated down-regulation, but not for signaling.

Bäckström BT, Rubin B, Peter A, Tiefenthaler G, Palmer E.

Eur J Immunol. 1997 Jun;27(6):1433-41.

PMID:
9209496
33.

A motif within the T cell receptor alpha chain constant region connecting peptide domain controls antigen responsiveness.

Bäckström BT, Milia E, Peter A, Jaureguiberry B, Baldari CT, Palmer E.

Immunity. 1996 Nov;5(5):437-47.

34.

CART: a conserved antigen receptor transmembrane motif.

Campbell KS, Bäckström BT, Tiefenthaler G, Palmer E.

Semin Immunol. 1994 Dec;6(6):393-410.

PMID:
7654996
35.

Identification of T cell stimulatory epitopes from the 18 kDa protein of Mycobacterium leprae.

Doherty TM, Bäckström BT, Love SG, Harding DR, Watson JD.

Int Immunol. 1993 Jun;5(6):673-80.

PMID:
7688563
37.
38.

New generation vaccines: does antibody play a directional role in antigen-processing?

Watson JD, Backstrom BT, Doherty TM.

Am J Trop Med Hyg. 1991 Apr;44(4 Pt 2):28-33.

PMID:
1710425
39.

Immune responses to the 18-kDa protein of Mycobacterium leprae. Similar B cell epitopes but different T cell epitopes seen by inbred strains of mice.

Doherty TM, Bäckström BT, Prestidge RL, Love SG, Harding DR, Watson JD.

J Immunol. 1991 Mar 15;146(6):1934-40.

PMID:
1706384
40.

The mapping of epitopes of the 18-kDa protein of Mycobacterium leprae recognized by murine T cells in a proliferation assay.

Harris DP, Bäckström BT, Booth RJ, Love SG, Harding DR, Watson JD.

J Immunol. 1989 Sep 15;143(6):2006-12.

PMID:
2476491
41.

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