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A "Dock and Lock" Approach to Preparation of Targeted Liposomes. Backer MV et al. Methods Mol Biol. (2017)

Antibiotic Therapy in the Treatment of Odontogenic Infections-An Evolving Landscape. Weeda L Jr et al. J Tenn Dent Assoc. (2016)

Rapid Imaging of Tumor Cell Death In Vivo Using the C2A Domain of Synaptotagmin-I. Neves AA et al. J Nucl Med. (2017)

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Items: 1 to 50 of 216


Changes in drug load during lacosamide combination therapy: A noninterventional, observational study in German and Austrian clinical practice.

Reinhardt F, Weber YG, Mayer T, Luef G, Joeres L, Tennigkeit F, Dedeken P, De Backer M, Hellot S, Lauterbach T, Webers T, Arnold S.

Epilepsia Open. 2019 Jun 22;4(3):409-419. doi: 10.1002/epi4.12346. eCollection 2019 Sep.


Targeting Fluorescent Nanodiamonds to Vascular Endothelial Growth Factor Receptors in Tumor.

Torelli MD, Rickard AG, Backer MV, Filonov DS, Nunn NA, Kinev AV, Backer JM, Palmer GM, Shenderova OA.

Bioconjug Chem. 2019 Mar 20;30(3):604-613. doi: 10.1021/acs.bioconjchem.8b00803. Epub 2019 Jan 31.


Do coaching style and game circumstances predict athletes' perceived justice of their coach? A longitudinal study in elite handball and volleyball teams.

De Backer M, Reynders B, Boen F, Van Puyenbroeck S, Vande Broek G.

PLoS One. 2018 Oct 15;13(10):e0205559. doi: 10.1371/journal.pone.0205559. eCollection 2018.


Pair Distribution Function Analysis of ZrO₂ Nanocrystals and Insights in the Formation of ZrO₂-YBa₂Cu₃O₇ Nanocomposites.

Rijckaert H, De Roo J, Van Zele M, Banerjee S, Huhtinen H, Paturi P, Bennewitz J, Billinge SJL, Bäcker M, De Buysser K, Van Driessche I.

Materials (Basel). 2018 Jun 23;11(7). pii: E1066. doi: 10.3390/ma11071066.


Imaging VEGF Receptors and αvβ3 Integrins in a Mouse Hindlimb Ischemia Model of Peripheral Arterial Disease.

Tekabe Y, Li Q, Zhang G, Johnson J, Schmidt AM, Backer M, Backer J, Johnson LL.

Mol Imaging Biol. 2018 Dec;20(6):963-972. doi: 10.1007/s11307-018-1191-1.


Safety and tolerability of lacosamide monotherapy in the elderly: A subgroup analysis from lacosamide trials in diabetic neuropathic pain.

Bainbridge J, De Backer M, Eckhardt K, Tennigkeit F, Bongardt S, Sen D, Werhahn KJ, Shaibani A, Faught E.

Epilepsia Open. 2017 Sep 11;2(4):415-423. doi: 10.1002/epi4.12079. eCollection 2017 Dec.


Lacosamide monotherapy in clinical practice: A retrospective chart review.

Villanueva V, Giráldez BG, Toledo M, De Haan GJ, Cumbo E, Gambardella A, De Backer M, Joeres L, Brunnert M, Dedeken P, Serratosa J.

Acta Neurol Scand. 2018 Sep;138(3):186-194. doi: 10.1111/ane.12920. Epub 2018 Mar 14.


Adjunctive lacosamide for focal epilepsy: an open-label trial evaluating the impact of flexible titration and dosing on safety and seizure outcomes.

Baulac M, Coulbaut S, Doty P, McShea C, De Backer M, Bartolomei F, Vlaicu M.

Epileptic Disord. 2017 Jun 1;19(2):186-194. doi: 10.1684/epd.2017.0907.


Selective Imaging of Vascular Endothelial Growth Factor Receptor-1 and Receptor-2 in Atherosclerotic Lesions in Diabetic and Non-diabetic ApoE-/- Mice.

Tekabe Y, Johnson LL, Rodriquez K, Li Q, Backer M, Backer JM.

Mol Imaging Biol. 2018 Feb;20(1):85-93. doi: 10.1007/s11307-017-1045-2.


Rapid Imaging of Tumor Cell Death In Vivo Using the C2A Domain of Synaptotagmin-I.

Neves AA, Xie B, Fawcett S, Alam IS, Witney TH, de Backer MM, Summers J, Hughes W, McGuire S, Soloviev D, Miller J, Howat WJ, Hu DE, Rodrigues TB, Lewis DY, Brindle KM.

J Nucl Med. 2017 Jun;58(6):881-887. doi: 10.2967/jnumed.116.183004. Epub 2017 Feb 16.


Efficacy, safety, and tolerability of lacosamide monotherapy versus controlled-release carbamazepine in patients with newly diagnosed epilepsy: a phase 3, randomised, double-blind, non-inferiority trial.

Baulac M, Rosenow F, Toledo M, Terada K, Li T, De Backer M, Werhahn KJ, Brock M.

Lancet Neurol. 2017 Jan;16(1):43-54. doi: 10.1016/S1474-4422(16)30292-7. Epub 2016 Nov 24. Erratum in: Lancet Neurol. 2017 Feb;16(2):102.


Bis-pyridylethenyl benzene as novel backbone for amyloid-β binding compounds.

Nabuurs RJ, Kapoerchan VV, Metaxas A, Hafith S, de Backer M, Welling MM, Jiskoot W, van den Nieuwendijk AM, Windhorst AD, Overkleeft HS, van Buchem MA, Overhand M, van der Weerd L.

Bioorg Med Chem. 2016 Dec 1;24(23):6139-6148. doi: 10.1016/j.bmc.2016.05.022. Epub 2016 May 18.


A "Dock and Lock" Approach to Preparation of Targeted Liposomes.

Backer MV, Backer JM.

Methods Mol Biol. 2017;1522:83-92.


Selective Imaging of VEGFR-1 and VEGFR-2 Using 89Zr-Labeled Single-Chain VEGF Mutants.

Meyer JP, Edwards KJ, Kozlowski P, Backer MV, Backer JM, Lewis JS.

J Nucl Med. 2016 Nov;57(11):1811-1816. Epub 2016 Jul 7.


Lacosamide and sodium channel-blocking antiepileptic drug cross-titration against levetiracetam background therapy.

Baulac M, Byrnes W, Williams P, Borghs S, Webster E, De Backer M, Dedeken P.

Acta Neurol Scand. 2017 Apr;135(4):434-441. doi: 10.1111/ane.12691. Epub 2016 Oct 6.


Antibiotic Therapy in the Treatment of Odontogenic Infections-An Evolving Landscape.

Weeda L Jr, Backer MJ.

J Tenn Dent Assoc. 2016 Fall;96(2):13-17. Review.


Randomized double-blind comparison of cognitive and EEG effects of lacosamide and carbamazepine.

Meador KJ, Loring DW, Boyd A, Echauz J, LaRoche S, Velez-Ruiz N, Korb P, Byrnes W, Dilley D, Borghs S, De Backer M, Story T, Dedeken P, Webster E.

Epilepsy Behav. 2016 Sep;62:267-75. doi: 10.1016/j.yebeh.2016.07.007. Epub 2016 Aug 10.


Changes in hormone and lipid levels in male patients with focal seizures when switched from carbamazepine to lacosamide as adjunctive treatment to levetiracetam: A small phase IIIb, prospective, multicenter, open-label trial.

Elger CE, Rademacher M, Brandt C, Elmoufti S, Dedeken P, Eckhardt K, Tennigkeit F, De Backer M.

Epilepsy Behav. 2016 Sep;62:1-5. doi: 10.1016/j.yebeh.2016.05.023. Epub 2016 Jul 15.


A long-term noninterventional safety study of adjunctive lacosamide therapy in patients with epilepsy and uncontrolled partial-onset seizures.

Steinhoff BJ, Eckhardt K, Doty P, De Backer M, Brunnert M, Schulze-Bonhage A.

Epilepsy Behav. 2016 May;58:35-43. doi: 10.1016/j.yebeh.2016.02.041. Epub 2016 Apr 4.


Targeted scVEGF/(177)Lu radiopharmaceutical inhibits growth of metastases and can be effectively combined with chemotherapy.

Rusckowski M, Wang Y, Blankenberg FG, Levashova Z, Backer MV, Backer JM.

EJNMMI Res. 2016 Dec;6(1):4. doi: 10.1186/s13550-016-0163-1. Epub 2016 Jan 16.


Pediatric Fistula Initiative: Reducing Bloodstream Infections in an Outpatient Pediatric Hemodialysis Center.

Chotikanatis K, Suman N, Bäcker M, Paudyal B, Schoeneman M, Kohlhoff S, Hammerschlag MR.

J Pediatric Infect Dis Soc. 2015 Dec;4(4):363-6. doi: 10.1093/jpids/piu053. Epub 2014 Jun 10.


Efficacy and safety of lacosamide as first add-on or later adjunctive treatment for uncontrolled partial-onset seizures: A multicentre open-label trial.

Zadeh WW, Escartin A, Byrnes W, Tennigkeit F, Borghs S, Li T, Dedeken P, De Backer M; SP0954 Study Group.

Seizure. 2015 Sep;31:72-9. doi: 10.1016/j.seizure.2015.07.001. Epub 2015 Jul 10.


Noninvasive Imaging of Liposomal Delivery of Superparamagnetic Iron Oxide Nanoparticles to Orthotopic Human Breast Tumor in Mice.

Kato Y, Zhu W, Backer MV, Neoh CC, Hapuarachchige S, Sarkar SK, Backer JM, Artemov D.

Pharm Res. 2015 Nov;32(11):3746-3755. doi: 10.1007/s11095-015-1736-9. Epub 2015 Jun 16.


Imaging VEGF receptor expression to identify accelerated atherosclerosis.

Tekabe Y, Kollaros M, Zerihoun A, Zhang G, Backer MV, Backer JM, Johnson LL.

EJNMMI Res. 2014 Dec;4(1):41. doi: 10.1186/s13550-014-0041-7. Epub 2014 Aug 1.


Monitoring of the Enzymatically Catalyzed Degradation of Biodegradable Polymers by Means of Capacitive Field-Effect Sensors.

Schusser S, Krischer M, Bäcker M, Poghossian A, Wagner P, Schöning MJ.

Anal Chem. 2015 Jul 7;87(13):6607-13. doi: 10.1021/acs.analchem.5b00617. Epub 2015 Jun 10.


On the tongue of our craft. 1964.

Backer M.

Conn Med. 2014 Oct;78(9):559-60. No abstract available.


Enhanced glutathione PEGylated liposomal brain delivery of an anti-amyloid single domain antibody fragment in a mouse model for Alzheimer's disease.

Rotman M, Welling MM, Bunschoten A, de Backer ME, Rip J, Nabuurs RJ, Gaillard PJ, van Buchem MA, van der Maarel SM, van der Weerd L.

J Control Release. 2015 Apr 10;203:40-50. doi: 10.1016/j.jconrel.2015.02.012. Epub 2015 Feb 7.


Gating capacitive field-effect sensors by the charge of nanoparticle/molecule hybrids.

Poghossian A, Bäcker M, Mayer D, Schöning MJ.

Nanoscale. 2015 Jan 21;7(3):1023-31. doi: 10.1039/c4nr05987e.


Does the "reef structure" at the ozone transition state towards the dissociation exist? New insight from calculations and ultrasensitive spectroscopy experiments.

Tyuterev VG, Kochanov R, Campargue A, Kassi S, Mondelain D, Barbe A, Starikova E, De Backer MR, Szalay PG, Tashkun S.

Phys Rev Lett. 2014 Oct 3;113(14):143002. Epub 2014 Oct 1.


Correlation of ultrasound-guided corticosteroid injection of the quadratus femoris with MRI findings of ischiofemoral impingement.

Backer MW, Lee KS, Blankenbaker DG, Kijowski R, Keene JS.

AJR Am J Roentgenol. 2014 Sep;203(3):589-93. doi: 10.2214/AJR.13.12304. Erratum in: AJR Am J Roentgenol. 2014 Nov;203(5):1156.


A team fares well with a fair coach: Predictors of social loafing in interactive female sport teams.

De Backer M, Boen F, De Cuyper B, Høigaard R, Vande Broek G.

Scand J Med Sci Sports. 2015 Dec;25(6):897-908. doi: 10.1111/sms.12303. Epub 2014 Aug 15.


Polyfluorinated bis-styrylbenzenes as amyloid-β plaque binding ligands.

Nabuurs RJ, Kapoerchan VV, Metaxas A, de Jongh S, de Backer M, Welling MM, Jiskoot W, Windhorst AD, Overkleeft HS, van Buchem MA, Overhand M, van der Weerd L.

Bioorg Med Chem. 2014 Apr 15;22(8):2469-81. doi: 10.1016/j.bmc.2014.02.054. Epub 2014 Mar 7.


Enhanced fluorescence diffuse optical tomography with indocyanine green-encapsulating liposomes targeted to receptors for vascular endothelial growth factor in tumor vasculature.

Zanganeh S, Xu Y, Hamby CV, Backer MV, Backer JM, Zhu Q.

J Biomed Opt. 2013 Dec;18(12):126014. doi: 10.1117/1.JBO.18.12.126014.


Membrane-bound SIV envelope trimers are immunogenic in ferrets after intranasal vaccination with a replication-competent canine distemper virus vector.

Zhang X, Wallace O, Wright KJ, Backer M, Coleman JW, Koehnke R, Frenk E, Domi A, Chiuchiolo MJ, DeStefano J, Narpala S, Powell R, Morrow G, Boggiano C, Zamb TJ, Richter King C, Parks CL.

Virology. 2013 Nov;446(1-2):25-36. doi: 10.1016/j.virol.2013.07.012. Epub 2013 Aug 9. Erratum in: Virology. 2014 Feb;450-451:371.


Genetic relationships in an international collection of Puccinia horiana isolates based on newly identified molecular markers and demonstration of recombination.

De Backer M, Bonants P, Pedley KF, Maes M, Roldan-Ruiz I, Van Bockstaele E, Heungens K, van der Lee T.

Phytopathology. 2013 Nov;103(11):1169-79. doi: 10.1094/PHYTO-01-13-0007-R.


Impact of stimulation dose and personality on autonomic and psychological effects induced by acupuncture.

Bäcker M, Schaefer F, Siegler N, Balzer S, Michalsen A, Langhorst J, Dobos GJ.

Auton Neurosci. 2012 Sep 25;170(1-2):48-55. doi: 10.1016/j.autneu.2012.07.002. Epub 2012 Jul 28.


Imaging key biomarkers of tumor angiogenesis.

Backer MV, Backer JM.

Theranostics. 2012;2(5):502-15. doi: 10.7150/thno.3623. Epub 2012 May 17.


Molecular imaging of vascular endothelial growth factor receptors in graft arteriosclerosis.

Zhang J, Razavian M, Tavakoli S, Nie L, Tellides G, Backer JM, Backer MV, Bender JR, Sadeghi MM.

Arterioscler Thromb Vasc Biol. 2012 Aug;32(8):1849-55. doi: 10.1161/ATVBAHA.112.252510. Epub 2012 Jun 21.


In vivo detection of amyloid-β deposits using heavy chain antibody fragments in a transgenic mouse model for Alzheimer's disease.

Nabuurs RJ, Rutgers KS, Welling MM, Metaxas A, de Backer ME, Rotman M, Bacskai BJ, van Buchem MA, van der Maarel SM, van der Weerd L.

PLoS One. 2012;7(6):e38284. doi: 10.1371/journal.pone.0038284. Epub 2012 Jun 4.


Chip-based amperometric enzyme sensor system for monitoring of bioprocesses by flow-injection analysis.

Bäcker M, Rakowski D, Poghossian A, Biselli M, Wagner P, Schöning MJ.

J Biotechnol. 2013 Feb 20;163(4):371-6. doi: 10.1016/j.jbiotec.2012.03.014. Epub 2012 Mar 23.


Transmission of carbapenem-resistant pathogens in New York City hospitals: progress and frustration.

Landman D, Babu E, Shah N, Kelly P, Olawole O, Bäcker M, Bratu S, Quale J.

J Antimicrob Chemother. 2012 Jun;67(6):1427-31. doi: 10.1093/jac/dks063. Epub 2012 Feb 29.


"Yes, we can!": Perceptions of collective efficacy sources in volleyball.

Fransen K, Vanbeselaere N, Exadaktylos V, Vande Broek G, De Cuyper B, Berckmans D, Ceux T, De Backer M, Boen F.

J Sports Sci. 2012;30(7):641-9. doi: 10.1080/02640414.2011.653579. Epub 2012 Feb 27.


Activity of polymyxin B and the novel polymyxin analogue CB-182,804 against contemporary Gram-negative pathogens in New York City.

Quale J, Shah N, Kelly P, Babu E, Backer M, Rosas-Garcia G, Salamera J, George A, Bratu S, Landman D.

Microb Drug Resist. 2012 Apr;18(2):132-6. doi: 10.1089/mdr.2011.0163. Epub 2011 Dec 23.


Recombinant adeno-associated viral vectors.

de Backer MW, Garner KM, Luijendijk MC, Adan RA.

Methods Mol Biol. 2011;789:357-76. doi: 10.1007/978-1-61779-310-3_24.


Mesenchymal stem cells induce resistance to chemotherapy through the release of platinum-induced fatty acids.

Roodhart JM, Daenen LG, Stigter EC, Prins HJ, Gerrits J, Houthuijzen JM, Gerritsen MG, Schipper HS, Backer MJ, van Amersfoort M, Vermaat JS, Moerer P, Ishihara K, Kalkhoven E, Beijnen JH, Derksen PW, Medema RH, Martens AC, Brenkman AB, Voest EE.

Cancer Cell. 2011 Sep 13;20(3):370-83. doi: 10.1016/j.ccr.2011.08.010.


Targeted systemic radiotherapy with scVEGF/177Lu leads to sustained disruption of the tumor vasculature and intratumoral apoptosis.

Blankenberg FG, Levashova Z, Goris MG, Hamby CV, Backer MV, Backer JM.

J Nucl Med. 2011 Oct;52(10):1630-7. doi: 10.2967/jnumed.111.091629. Epub 2011 Sep 2.


Recurrent intravascular-catheter-related bacteremia caused by Delftia acidovorans in a hemodialysis patient.

Chotikanatis K, Bäcker M, Rosas-Garcia G, Hammerschlag MR.

J Clin Microbiol. 2011 Sep;49(9):3418-21. doi: 10.1128/JCM.00625-11. Epub 2011 Jul 20.


Effectiveness of leech therapy in chronic lateral epicondylitis: a randomized controlled trial.

Bäcker M, Lüdtke R, Afra D, Cesur O, Langhorst J, Fink M, Bachmann J, Dobos GJ, Michalsen A.

Clin J Pain. 2011 Jun;27(5):442-7. doi: 10.1097/AJP.0b013e318208c95b.


Targeting the unfolded protein response in cancer therapy.

Backer MV, Backer JM, Chinnaiyan P.

Methods Enzymol. 2011;491:37-56. doi: 10.1016/B978-0-12-385928-0.00003-1.


Both overexpression of agouti-related peptide or neuropeptide Y in the paraventricular nucleus or lateral hypothalamus induce obesity in a neuropeptide- and nucleus specific manner.

de Backer MW, la Fleur SE, Adan RA.

Eur J Pharmacol. 2011 Jun 11;660(1):148-55. doi: 10.1016/j.ejphar.2010.12.021. Epub 2011 Jan 3. Review.


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