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Best matches for Bächinger HP[au]:

Osteogenesis imperfecta. Marini JC et al. Nat Rev Dis Primers. (2017)

The HDAC3-SMARCA4-miR-27a axis promotes expression of the <i>PAX3:FOXO1</i> fusion oncogene in rhabdomyosarcoma. Bharathy N et al. Sci Signal. (2018)

A Novel Antifibrotic Mechanism of Nintedanib and Pirfenidone. Inhibition of Collagen Fibril Assembly. Knüppel L et al. Am J Respir Cell Mol Biol. (2017)

Search results

Items: 1 to 50 of 153

1.

The novel missense mutation Met48Lys in FKBP22 changes its structure and functions.

Ishikawa Y, Mizuno N, Holden P, Lim PJ, Gould DB, Rohrbach M, Giunta C, Bächinger HP.

Sci Rep. 2020 Jan 16;10(1):497. doi: 10.1038/s41598-019-57374-y.

2.

Sex effects of dietary protein source and acid load on renal and bone status in the Pahenu2 mouse model of phenylketonuria.

Stroup BM, Murali SG, Schwahn DJ, Sawin EA, Lankey EM, Bächinger HP, Ney DM.

Physiol Rep. 2019 Oct;7(20):e14251. doi: 10.14814/phy2.14251.

3.

A ribose modification of Spinach aptamer accelerates lead(ii) cation association in vitro.

Savage JC, Shinde P, Bächinger HP, Davare MA, Shinde U.

Chem Commun (Camb). 2019 May 25;55(42):5882-5885. doi: 10.1039/c9cc01697j. Epub 2019 Apr 30.

PMID:
31037281
4.

The HDAC3-SMARCA4-miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma.

Bharathy N, Berlow NE, Wang E, Abraham J, Settelmeyer TP, Hooper JE, Svalina MN, Ishikawa Y, Zientek K, Bajwa Z, Goros MW, Hernandez BS, Wolff JE, Rudek MA, Xu L, Anders NM, Pal R, Harrold AP, Davies AM, Ashok A, Bushby D, Mancini M, Noakes C, Goodwin NC, Ordentlich P, Keck J, Hawkins DS, Rudzinski ER, Chatterjee B, Bächinger HP, Barr FG, Liddle J, Garcia BA, Mansoor A, Perkins TJ, Vakoc CR, Michalek JE, Keller C.

Sci Signal. 2018 Nov 20;11(557). pii: eaau7632. doi: 10.1126/scisignal.aau7632.

5.

The endoplasmic reticulum-resident collagen chaperone Hsp47 interacts with and promotes the secretion of decorin, fibromodulin, and lumican.

Ishikawa Y, Rubin K, Bächinger HP, Kalamajski S.

J Biol Chem. 2018 Aug 31;293(35):13707-13716. doi: 10.1074/jbc.RA117.000758. Epub 2018 Jul 12.

6.

Type III collagen affects dermal and vascular collagen fibrillogenesis and tissue integrity in a mutant Col3a1 transgenic mouse model.

D'hondt S, Guillemyn B, Syx D, Symoens S, De Rycke R, Vanhoutte L, Toussaint W, Lambrecht BN, De Paepe A, Keene DR, Ishikawa Y, Bächinger HP, Janssens S, Bertrand MJM, Malfait F.

Matrix Biol. 2018 Sep;70:72-83. doi: 10.1016/j.matbio.2018.03.008. Epub 2018 Mar 15.

PMID:
29551664
7.

Post-translational modification of type IV collagen with 3-hydroxyproline affects its interactions with glycoprotein VI and nidogens 1 and 2.

Montgomery NT, Zientek KD, Pokidysheva EN, Bächinger HP.

J Biol Chem. 2018 Apr 20;293(16):5987-5999. doi: 10.1074/jbc.RA117.000406. Epub 2018 Feb 28.

8.

Heat shock protein 47 and 65-kDa FK506-binding protein weakly but synergistically interact during collagen folding in the endoplasmic reticulum.

Ishikawa Y, Holden P, Bächinger HP.

J Biol Chem. 2017 Oct 20;292(42):17216-17224. doi: 10.1074/jbc.M117.802298. Epub 2017 Aug 31.

9.

Osteogenesis imperfecta.

Marini JC, Forlino A, Bächinger HP, Bishop NJ, Byers PH, Paepe A, Fassier F, Fratzl-Zelman N, Kozloff KM, Krakow D, Montpetit K, Semler O.

Nat Rev Dis Primers. 2017 Aug 18;3:17052. doi: 10.1038/nrdp.2017.52. Review.

PMID:
28820180
10.

Ziploc-ing the structure 2.0: Endoplasmic reticulum-resident peptidyl prolyl isomerases show different activities toward hydroxyproline.

Ishikawa Y, Mizuno K, Bächinger HP.

J Biol Chem. 2017 Jun 2;292(22):9273-9282. doi: 10.1074/jbc.M116.772657. Epub 2017 Apr 6.

11.

A Novel Antifibrotic Mechanism of Nintedanib and Pirfenidone. Inhibition of Collagen Fibril Assembly.

Knüppel L, Ishikawa Y, Aichler M, Heinzelmann K, Hatz R, Behr J, Walch A, Bächinger HP, Eickelberg O, Staab-Weijnitz CA.

Am J Respir Cell Mol Biol. 2017 Jul;57(1):77-90. doi: 10.1165/rcmb.2016-0217OC.

PMID:
28257580
12.

Structural insight for chain selection and stagger control in collagen.

Boudko SP, Bächinger HP.

Sci Rep. 2016 Nov 29;6:37831. doi: 10.1038/srep37831.

13.

Intracellular mechanisms of molecular recognition and sorting for transport of large extracellular matrix molecules.

Ishikawa Y, Ito S, Nagata K, Sakai LY, Bächinger HP.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6036-E6044. Epub 2016 Sep 27.

14.

Bone matrix hypermineralization in prolyl-3 hydroxylase 1 deficient mice.

Fratzl-Zelman N, Bächinger HP, Vranka JA, Roschger P, Klaushofer K, Rauch F.

Bone. 2016 Apr;85:15-22. doi: 10.1016/j.bone.2016.01.018. Epub 2016 Jan 22.

PMID:
26808442
15.

TRAIL-Based High Throughput Screening Reveals a Link between TRAIL-Mediated Apoptosis and Glutathione Reductase, a Key Component of Oxidative Stress Response.

Rozanov D, Cheltsov A, Sergienko E, Vasile S, Golubkov V, Aleshin AE, Levin T, Traer E, Hann B, Freimuth J, Alexeev N, Alekseyev MA, Budko SP, Bächinger HP, Spellman P.

PLoS One. 2015 Jun 15;10(6):e0129566. doi: 10.1371/journal.pone.0129566. eCollection 2015.

16.

Recessive osteogenesis imperfecta caused by missense mutations in SPARC.

Mendoza-Londono R, Fahiminiya S, Majewski J; Care4Rare Canada Consortium, Tétreault M, Nadaf J, Kannu P, Sochett E, Howard A, Stimec J, Dupuis L, Roschger P, Klaushofer K, Palomo T, Ouellet J, Al-Jallad H, Mort JS, Moffatt P, Boudko S, Bächinger HP, Rauch F.

Am J Hum Genet. 2015 Jun 4;96(6):979-85. doi: 10.1016/j.ajhg.2015.04.021. Epub 2015 May 28.

17.

Conformational change from rigid rod to star: a triple-helical peptide with a linker domain at the C-terminal end.

Terao K, Mizuno K, Bächinger HP.

J Phys Chem B. 2015 Mar 5;119(9):3714-9. doi: 10.1021/jp5129172. Epub 2015 Feb 23.

PMID:
25685884
18.

Cole-Carpenter syndrome is caused by a heterozygous missense mutation in P4HB.

Rauch F, Fahiminiya S, Majewski J, Carrot-Zhang J, Boudko S, Glorieux F, Mort JS, Bächinger HP, Moffatt P.

Am J Hum Genet. 2015 Mar 5;96(3):425-31. doi: 10.1016/j.ajhg.2014.12.027. Epub 2015 Feb 12.

19.

Ziploc-ing the structure: Triple helix formation is coordinated by rough endoplasmic reticulum resident PPIases.

Ishikawa Y, Boudko S, Bächinger HP.

Biochim Biophys Acta. 2015 Oct;1850(10):1983-93. doi: 10.1016/j.bbagen.2014.12.024. Epub 2015 Jan 10. Review.

PMID:
25583561
20.

A substrate preference for the rough endoplasmic reticulum resident protein FKBP22 during collagen biosynthesis.

Ishikawa Y, Bächinger HP.

J Biol Chem. 2014 Jun 27;289(26):18189-201. doi: 10.1074/jbc.M114.561944. Epub 2014 May 12.

21.

Excessive transforming growth factor-β signaling is a common mechanism in osteogenesis imperfecta.

Grafe I, Yang T, Alexander S, Homan EP, Lietman C, Jiang MM, Bertin T, Munivez E, Chen Y, Dawson B, Ishikawa Y, Weis MA, Sampath TK, Ambrose C, Eyre D, Bächinger HP, Lee B.

Nat Med. 2014 Jun;20(6):670-5. doi: 10.1038/nm.3544. Epub 2014 May 4.

22.

Biological role of prolyl 3-hydroxylation in type IV collagen.

Pokidysheva E, Boudko S, Vranka J, Zientek K, Maddox K, Moser M, Fässler R, Ware J, Bächinger HP.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):161-6. doi: 10.1073/pnas.1307597111. Epub 2013 Dec 24.

23.

Structure of human peptidyl-prolyl cis-trans isomerase FKBP22 containing two EF-hand motifs.

Boudko SP, Ishikawa Y, Nix J, Chapman MS, Bächinger HP.

Protein Sci. 2014 Jan;23(1):67-75. doi: 10.1002/pro.2391. Epub 2013 Nov 25.

24.

The concave face of decorin mediates reversible dimerization and collagen binding.

Islam M, Gor J, Perkins SJ, Ishikawa Y, Bächinger HP, Hohenester E.

J Biol Chem. 2013 Dec 6;288(49):35526-33. doi: 10.1074/jbc.M113.504530. Epub 2013 Oct 29.

25.

Deficiency for the ER-stress transducer OASIS causes severe recessive osteogenesis imperfecta in humans.

Symoens S, Malfait F, D'hondt S, Callewaert B, Dheedene A, Steyaert W, Bächinger HP, De Paepe A, Kayserili H, Coucke PJ.

Orphanet J Rare Dis. 2013 Sep 30;8:154. doi: 10.1186/1750-1172-8-154.

27.

Posttranslational modifications in type I collagen from different tissues extracted from wild type and prolyl 3-hydroxylase 1 null mice.

Pokidysheva E, Zientek KD, Ishikawa Y, Mizuno K, Vranka JA, Montgomery NT, Keene DR, Kawaguchi T, Okuyama K, Bächinger HP.

J Biol Chem. 2013 Aug 23;288(34):24742-52. doi: 10.1074/jbc.M113.464156. Epub 2013 Jul 16.

28.

Vascular Ehlers-Danlos syndrome mutations in type III collagen differently stall the triple helical folding.

Mizuno K, Boudko S, Engel J, Bächinger HP.

J Biol Chem. 2013 Jun 28;288(26):19166-76. doi: 10.1074/jbc.M113.462002. Epub 2013 May 3.

29.

Crystal structure of the collagen model peptide (Pro-Pro-Gly)4-Hyp-Asp-Gly-(Pro-Pro-Gly)4 at 1.0 Å resolution.

Okuyama K, Kawaguchi T, Shimura M, Noguchi K, Mizuno K, Bächinger HP.

Biopolymers. 2013 Jul;99(7):436-47. doi: 10.1002/bip.22198.

PMID:
23616212
30.

A molecular ensemble in the rER for procollagen maturation.

Ishikawa Y, Bächinger HP.

Biochim Biophys Acta. 2013 Nov;1833(11):2479-91. doi: 10.1016/j.bbamcr.2013.04.008. Epub 2013 Apr 18. Review.

31.

Analytical methods for measuring collagen XIX in human cell cultures, tissue extracts, and biological fluids.

Oudart JB, Brassart-Pasco S, Luczka E, Dupont-Deshorgue A, Bellon G, Boudko SP, Bächinger HP, Monboisse JC, Maquart FX, Ramont L.

Anal Biochem. 2013 Jun 15;437(2):111-7. doi: 10.1016/j.ab.2013.03.007. Epub 2013 Mar 14.

PMID:
23499763
32.

Prolyl 3-hydroxylase-1 null mice exhibit hearing impairment and abnormal morphology of the middle ear bone joints.

Pokidysheva E, Tufa S, Bresee C, Brigande JV, Bächinger HP.

Matrix Biol. 2013 Jan;32(1):39-44. doi: 10.1016/j.matbio.2012.11.006. Epub 2012 Nov 24.

33.

Crystal structures of wild-type and mutated cyclophilin B that causes hyperelastosis cutis in the American quarter horse.

Boudko SP, Ishikawa Y, Lerch TF, Nix J, Chapman MS, Bächinger HP.

BMC Res Notes. 2012 Nov 8;5:626. doi: 10.1186/1756-0500-5-626.

34.

The NC2 domain of type IX collagen determines the chain register of the triple helix.

Boudko SP, Bächinger HP.

J Biol Chem. 2012 Dec 28;287(53):44536-45. doi: 10.1074/jbc.M112.417543. Epub 2012 Nov 6.

35.

Fragility of reconstituted type V collagen fibrils with the chain composition of α1(V)α2(V)α3(V) respective of the D-periodic banding pattern.

Mizuno K, Bächinger HP, Imamura Y, Hayashi T, Adachi E.

Connect Tissue Res. 2013;54(1):41-8. doi: 10.3109/03008207.2012.734876. Epub 2012 Dec 3.

PMID:
23092503
36.

Crystal structure of (Gly-Pro-Hyp)(9) : implications for the collagen molecular model.

Okuyama K, Miyama K, Mizuno K, Bächinger HP.

Biopolymers. 2012 Aug;97(8):607-16. doi: 10.1002/bip.22048.

PMID:
22605552
37.

Mutation in cyclophilin B that causes hyperelastosis cutis in American Quarter Horse does not affect peptidylprolyl cis-trans isomerase activity but shows altered cyclophilin B-protein interactions and affects collagen folding.

Ishikawa Y, Vranka JA, Boudko SP, Pokidysheva E, Mizuno K, Zientek K, Keene DR, Rashmir-Raven AM, Nagata K, Winand NJ, Bächinger HP.

J Biol Chem. 2012 Jun 22;287(26):22253-65. doi: 10.1074/jbc.M111.333336. Epub 2012 May 3.

38.

The crucial role of trimerization domains in collagen folding.

Boudko SP, Engel J, Bächinger HP.

Int J Biochem Cell Biol. 2012 Jan;44(1):21-32. doi: 10.1016/j.biocel.2011.09.009. Epub 2011 Oct 5. Review.

PMID:
22001560
39.

HIV-1 matrix protein binding to RNA.

Alfadhli A, McNett H, Tsagli S, Bächinger HP, Peyton DH, Barklis E.

J Mol Biol. 2011 Jul 22;410(4):653-66. doi: 10.1016/j.jmb.2011.04.063.

40.

Stabilization of triple-helical structures of collagen peptides containing a Hyp-Thr-Gly, Hyp-Val-Gly, or Hyp-Ser-Gly sequence.

Okuyama K, Miyama K, Morimoto T, Masakiyo K, Mizuno K, Bächinger HP.

Biopolymers. 2011 Sep;95(9):628-40. doi: 10.1002/bip.21625. Epub 2011 Mar 25.

PMID:
21442606
41.

Crystal structure of the human collagen XV trimerization domain: a potent trimerizing unit common to multiplexin collagens.

Wirz JA, Boudko SP, Lerch TF, Chapman MS, Bächinger HP.

Matrix Biol. 2011 Jan;30(1):9-15. doi: 10.1016/j.matbio.2010.09.005. Epub 2010 Oct 13.

42.

Laminin-121--recombinant expression and interactions with integrins.

Sasaki T, Takagi J, Giudici C, Yamada Y, Arikawa-Hirasawa E, Deutzmann R, Timpl R, Sonnenberg A, Bächinger HP, Tonge D.

Matrix Biol. 2010 Jul;29(6):484-93. doi: 10.1016/j.matbio.2010.05.004. Epub 2010 May 23.

43.

Kinetic hysteresis in collagen folding.

Mizuno K, Boudko SP, Engel J, Bächinger HP.

Biophys J. 2010 Jun 16;98(12):3004-14. doi: 10.1016/j.bpj.2010.03.019.

44.

The NC2 domain of collagen IX provides chain selection and heterotrimerization.

Boudko SP, Zientek KD, Vance J, Hacker JL, Engel J, Bächinger HP.

J Biol Chem. 2010 Jul 30;285(31):23721-31. doi: 10.1074/jbc.M110.128405. Epub 2010 May 27.

45.

Prolyl 3-hydroxylase 1 null mice display abnormalities in fibrillar collagen-rich tissues such as tendons, skin, and bones.

Vranka JA, Pokidysheva E, Hayashi L, Zientek K, Mizuno K, Ishikawa Y, Maddox K, Tufa S, Keene DR, Klein R, Bächinger HP.

J Biol Chem. 2010 May 28;285(22):17253-62. doi: 10.1074/jbc.M110.102228. Epub 2010 Apr 2. Erratum in: J Biol Chem. 2010 Jun 25;285(26):20421.

46.

Two crystal modifications of (Pro-Pro-Gly)4-Hyp-Hyp-Gly-(Pro-Pro-Gly)4 reveal the puckering preference of Hyp(X) in the Hyp(X):Hyp(Y) and Hyp(X):Pro(Y) stacking pairs in collagen helices.

Okuyama K, Morimoto T, Narita H, Kawaguchi T, Mizuno K, Bächinger HP, Wu G, Noguchi K.

Acta Crystallogr D Biol Crystallogr. 2010 Jan;66(Pt 1):88-96. doi: 10.1107/S0907444909046642. Epub 2009 Dec 21.

PMID:
20057053
47.
48.

Re: Microfibrillar structure of type I collagen in situ.

Okuyama K, Bächinger HP, Mizuno K, Boudko S, Engel J, Berisio R, Vitagliano L.

Acta Crystallogr D Biol Crystallogr. 2009 Sep;65(Pt 9):1007-8; author reply 1009-10. doi: 10.1107/S0907444909023051. Epub 2009 Aug 14. No abstract available.

PMID:
19690380
49.

Expression of prolyl 3-hydroxylase genes in embryonic and adult mouse tissues.

Vranka J, Stadler HS, Bächinger HP.

Cell Struct Funct. 2009;34(2):97-104. Epub 2009 Aug 1.

50.

Crystal structure of human collagen XVIII trimerization domain: A novel collagen trimerization Fold.

Boudko SP, Sasaki T, Engel J, Lerch TF, Nix J, Chapman MS, Bächinger HP.

J Mol Biol. 2009 Sep 25;392(3):787-802. doi: 10.1016/j.jmb.2009.07.057. Epub 2009 Jul 23.

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