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Items: 1 to 50 of 458

1.

Nintedanib in patients with systemic sclerosis associated interstitial lung disease: A Japanese population analysis of the SENSCIS trial.

Kuwana M, Ogura T, Makino S, Homma S, Kondoh Y, Saito A, Ugai H, Gahlemann M, Takehara K, Azuma A.

Mod Rheumatol. 2020 Apr 3:1-26. doi: 10.1080/14397595.2020.1751402. [Epub ahead of print]

PMID:
32243207
2.

Reply to: Thrombomodulin Did Not Benefit Acute Exacerbation of Idiopathic Pulmonary Fibrosis in a Trial.

Kondoh Y, Azuma A, Tagawa J, Homma S.

Am J Respir Crit Care Med. 2020 Mar 31. doi: 10.1164/rccm.202003-0666LE. [Epub ahead of print] No abstract available.

PMID:
32228231
3.

Efforts to control air pollution in the Asia-Pacific region.

Morimoto Y, Khatun H, Yee KSW, Susanto AD, Myong JP, Tanchuco JJ, Sheu CC, Chau NQ, Azuma A.

Respirology. 2020 Mar 24. doi: 10.1111/resp.13800. [Epub ahead of print] Review. No abstract available.

PMID:
32212187
4.

Reply to: Too Premature to Deny the Potential of Thrombomodulin-alfa in Idiopathic Pulmonary Fibrosis.

Kondoh Y, Azuma A, Tagawa J, Yamamori N, Homma S.

Am J Respir Crit Care Med. 2020 Mar 9. doi: 10.1164/rccm.202002-0398LE. [Epub ahead of print] No abstract available.

PMID:
32150449
5.

Thrombomodulin alfa for Acute Exacerbation of Idiopathic Pulmonary Fibrosis: A Randomized, Double-blind, Placebo-controlled Trial.

Kondoh Y, Azuma A, Inoue Y, Ogura T, Sakamoto S, Tsushima K, Johkoh T, Fujimoto K, Ichikado K, Matsuzawa Y, Saito T, Kishi K, Tomii K, Sakamoto N, Aoshima M, Araya J, Izumi S, Arita M, Abe M, Yamauchi H, Shindoh J, Suda T, Okamoto M, Ebina M, Yamada Y, Tohda Y, Kawamura T, Taguchi Y, Ishii H, Hashimoto N, Abe S, Taniguchi H, Tagawa J, Bessho K, Yamamori N, Homma S.

Am J Respir Crit Care Med. 2020 Jan 9. doi: 10.1164/rccm.201909-1818OC. [Epub ahead of print]

PMID:
31917621
6.

Exosome-derived microRNA-22 ameliorates pulmonary fibrosis by regulating fibroblast-to-myofibroblast differentiation both in vitro and in vivo.

Kuse N, Kamio K, Azuma A, Matsuda K, Inomata M, Usuki J, Morinaga A, Tanaka T, Kashiwada T, Atsumi K, Hayashi H, Saito Y, Seike M, Gemma A.

J Nippon Med Sch. 2019 Nov 28. doi: 10.1272/jnms.JNMS.2020_87-302. [Epub ahead of print]

7.

Nintedanib: New indication for systemic sclerosis-associated interstitial lung disease.

Kuwana M, Azuma A.

Mod Rheumatol. 2020 Mar;30(2):225-231. doi: 10.1080/14397595.2019.1696505. Epub 2019 Dec 20. Erratum in: Mod Rheumatol. 2019 Dec 20;:1.

PMID:
31747840
8.

Primary ciliary dyskinesia caused by a large homozygous deletion including exons 1-4 of DRC1 in Japanese patients with recurrent sinopulmonary infection.

Keicho N, Hijikata M, Morimoto K, Homma S, Taguchi Y, Azuma A, Kudoh S.

Mol Genet Genomic Med. 2020 Jan;8(1):e1033. doi: 10.1002/mgg3.1033. Epub 2019 Nov 8.

9.

JCS 2016 Guideline on Diagnosis and Treatment of Cardiac Sarcoidosis - Digest Version.

Terasaki F, Azuma A, Anzai T, Ishizaka N, Ishida Y, Isobe M, Inomata T, Ishibashi-Ueda H, Eishi Y, Kitakaze M, Kusano K, Sakata Y, Shijubo N, Tsuchida A, Tsutsui H, Nakajima T, Nakatani S, Horii T, Yazaki Y, Yamaguchi E, Yamaguchi T, Ide T, Okamura H, Kato Y, Goya M, Sakakibara M, Soejima K, Nagai T, Nakamura H, Noda T, Hasegawa T, Morita H, Ohe T, Kihara Y, Saito Y, Sugiyama Y, Morimoto SI, Yamashina A; Japanese Circulation Society Joint Working Group.

Circ J. 2019 Oct 25;83(11):2329-2388. doi: 10.1253/circj.CJ-19-0508. Epub 2019 Oct 9. No abstract available.

10.

Outcomes following decline in forced vital capacity in patients with idiopathic pulmonary fibrosis: Results from the INPULSIS and INPULSIS-ON trials of nintedanib.

Richeldi L, Crestani B, Azuma A, Kolb M, Selman M, Stansen W, Quaresma M, Stowasser S, Cottin V.

Respir Med. 2019 Sep;156:20-25. doi: 10.1016/j.rmed.2019.08.002. Epub 2019 Aug 6.

PMID:
31404749
11.

Weekly paclitaxel in combination with carboplatin for advanced non-small-cell lung cancer complicated by idiopathic interstitial pneumonias: a single-arm phase II study.

Fukuizumi A, Minegishi Y, Omori M, Atsumi K, Takano N, Hisakane K, Takahashi S, Kobayashi K, Sugano T, Takeuchi S, Noro R, Seike M, Kubota K, Azuma A, Gemma A.

Int J Clin Oncol. 2019 Dec;24(12):1543-1548. doi: 10.1007/s10147-019-01516-9. Epub 2019 Jul 27.

PMID:
31352631
12.

Extemporaneous Preparation of Injectable and Enzymatically Degradable 3D Cell Culture Matrices from an Animal-Component-Free Recombinant Protein Based on Human Collagen Type I.

Kamata H, Ashikari-Hada S, Mori Y, Azuma A, Hata KI.

Macromol Rapid Commun. 2019 Aug;40(15):e1900127. doi: 10.1002/marc.201900127. Epub 2019 May 28.

PMID:
31136037
13.

Analysis of the Genetic Diversity and Structure of the Grey-Faced Buzzard (Butastur indicus) in Japan, Based on mtDNA.

Nagai K, Iseki F, Azuma A.

Zoolog Sci. 2019 Feb 1;36(1):17-22. doi: 10.2108/zs180077.

PMID:
31116534
14.

Nintedanib for Systemic Sclerosis-Associated Interstitial Lung Disease.

Distler O, Highland KB, Gahlemann M, Azuma A, Fischer A, Mayes MD, Raghu G, Sauter W, Girard M, Alves M, Clerisme-Beaty E, Stowasser S, Tetzlaff K, Kuwana M, Maher TM; SENSCIS Trial Investigators.

N Engl J Med. 2019 Jun 27;380(26):2518-2528. doi: 10.1056/NEJMoa1903076. Epub 2019 May 20.

15.

Severe Pneumonitis with Alveolar Hemorrhage Associated with Herbal Medicines: A Case Report.

Omori M, Saito Y, Miura Y, Tanaka T, Kashiwada T, Atsumi K, Hayashi H, Minegishi Y, Fujita K, Azuma A, Seike M, Gemma A.

J Nippon Med Sch. 2019 Dec 3;86(5):296-300. doi: 10.1272/jnms.JNMS.2019_86-504. Epub 2019 May 17.

16.

Activated Fibroblast Program Orchestrates Tumor Initiation and Progression; Molecular Mechanisms and the Associated Therapeutic Strategies.

Yoshida GJ, Azuma A, Miura Y, Orimo A.

Int J Mol Sci. 2019 May 7;20(9). pii: E2256. doi: 10.3390/ijms20092256. Review.

17.

Criteria for the diagnosis of idiopathic pleuroparenchymal fibroelastosis: A proposal.

Watanabe K, Ishii H, Kiyomi F, Terasaki Y, Hebisawa A, Kawabata Y, Johkoh T, Sakai F, Kondoh Y, Inoue Y, Azuma A, Suda T, Ogura T, Inase N, Homma S; Study Group on Diffuse Pulmonary Disorders, Scientific Research/Research on Intractable Diseases in Japan.

Respir Investig. 2019 Jul;57(4):312-320. doi: 10.1016/j.resinv.2019.02.007. Epub 2019 Apr 10. Review.

PMID:
30981683
18.

Lung function outcomes in the INPULSIS® trials of nintedanib in idiopathic pulmonary fibrosis.

Brown KK, Flaherty KR, Cottin V, Raghu G, Inoue Y, Azuma A, Huggins JT, Richeldi L, Stowasser S, Stansen W, Schlenker-Herceg R, Maher TM, Wells AU.

Respir Med. 2019 Jan;146:42-48. doi: 10.1016/j.rmed.2018.11.012. Epub 2018 Nov 19.

19.

Therapeutic effects of nintedanib are not influenced by emphysema in the INPULSIS trials.

Cottin V, Azuma A, Raghu G, Stansen W, Stowasser S, Schlenker-Herceg R, Kolb M.

Eur Respir J. 2019 Apr 18;53(4). pii: 1801655. doi: 10.1183/13993003.01655-2018. Print 2019 Apr. No abstract available.

PMID:
30655282
20.

Long-term safety of pirfenidone: results of the prospective, observational PASSPORT study.

Cottin V, Koschel D, Günther A, Albera C, Azuma A, Sköld CM, Tomassetti S, Hormel P, Stauffer JL, Strombom I, Kirchgaessler KU, Maher TM.

ERJ Open Res. 2018 Oct 19;4(4). pii: 00084-2018. doi: 10.1183/23120541.00084-2018. eCollection 2018 Oct.

21.

An on-site preparable, novel bone-grafting complex consisting of human platelet-rich fibrin and porous particles made of a recombinant collagen-like protein.

Tsukioka T, Hiratsuka T, Nakamura M, Watanabe T, Kitamura Y, Isobe K, Okudera T, Okudera H, Azuma A, Uematsu K, Nakata K, Kawase T.

J Biomed Mater Res B Appl Biomater. 2019 Jul;107(5):1420-1430. doi: 10.1002/jbm.b.34234. Epub 2018 Oct 1.

22.

Diagnosis of Idiopathic Pulmonary Fibrosis. An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline.

Raghu G, Remy-Jardin M, Myers JL, Richeldi L, Ryerson CJ, Lederer DJ, Behr J, Cottin V, Danoff SK, Morell F, Flaherty KR, Wells A, Martinez FJ, Azuma A, Bice TJ, Bouros D, Brown KK, Collard HR, Duggal A, Galvin L, Inoue Y, Jenkins RG, Johkoh T, Kazerooni EA, Kitaichi M, Knight SL, Mansour G, Nicholson AG, Pipavath SNJ, Buendía-Roldán I, Selman M, Travis WD, Walsh S, Wilson KC; American Thoracic Society, European Respiratory Society, Japanese Respiratory Society, and Latin American Thoracic Society.

Am J Respir Crit Care Med. 2018 Sep 1;198(5):e44-e68. doi: 10.1164/rccm.201807-1255ST.

PMID:
30168753
23.

Cytometrical analysis of the adverse effects of indican, indoxyl, indigo, and indirubin on rat thymic lymphocytes.

Funakoshi Y, Azuma A, Ishikawa M, Itsuki S, Tamura Y, Kanemaru K, Hirai S, Oyama Y.

Toxicol Res (Camb). 2018 Mar 28;7(3):513-520. doi: 10.1039/c7tx00244k. eCollection 2018 May 8.

24.

Diffuse panbronchiolitis: A fine road from the discovery of a disease to the establishment of treatment.

Kamio K, Azuma A.

Respir Investig. 2018 Sep;56(5):373-374. doi: 10.1016/j.resinv.2018.07.001. Epub 2018 Jul 23. No abstract available.

PMID:
30049592
25.

Japanese guideline for the treatment of idiopathic pulmonary fibrosis.

Homma S, Bando M, Azuma A, Sakamoto S, Sugino K, Ishii Y, Izumi S, Inase N, Inoue Y, Ebina M, Ogura T, Kishi K, Kishaba T, Kido T, Gemma A, Goto Y, Sasaki S, Johkoh T, Suda T, Takahashi K, Takahashi H, Taguchi Y, Date H, Taniguchi H, Nakayama T, Nishioka Y, Hasegawa Y, Hattori N, Fukuoka J, Miyamoto A, Mukae H, Yokoyama A, Yoshino I, Watanabe K; Ministry of Health, Labour and Welfare, the Study Group on Diffuse Pulmonary Disorders, Scientific Research/Research on Intractable Diseases, and Japanese Respiratory Society.

Respir Investig. 2018 Jul;56(4):268-291. doi: 10.1016/j.resinv.2018.03.003. Epub 2018 Jul 3. Review.

PMID:
29980444
26.

Prognostic significance of ventricular late potentials in patients with pulmonary sarcoidosis.

Yodogawa K, Seino Y, Ohara T, Iwasaki YK, Hayashi M, Miyauchi Y, Azuma A, Shimizu W.

Heart Rhythm. 2018 Jun;15(6):798-802. doi: 10.1016/j.hrthm.2018.03.013.

PMID:
29857850
27.

Resolution of bleomycin-induced murine pulmonary fibrosis via a splenic lymphocyte subpopulation.

Kamio K, Azuma A, Matsuda K, Usuki J, Inomata M, Morinaga A, Kashiwada T, Nishijima N, Itakura S, Kokuho N, Atsumi K, Hayashi H, Yamaguchi T, Fujita K, Saito Y, Abe S, Kubota K, Gemma A.

Respir Res. 2018 Apr 24;19(1):71. doi: 10.1186/s12931-018-0783-2.

28.

A Community-Level Initiative to Prevent Obesity: Results From Kaiser Permanente's Healthy Eating Active Living Zones Initiative in California.

Cheadle A, Atiedu A, Rauzon S, Schwartz PM, Keene L, Davoudi M, Spring R, Molina M, Lee L, Boyle K, Williamson D, Steimberg C, Tinajero R, Ravel J, Nudelman J, Azuma AM, Kuo ES, Solomon L.

Am J Prev Med. 2018 May;54(5 Suppl 2):S150-S159. doi: 10.1016/j.amepre.2018.01.024.

29.

Reduced incidence of lung cancer in patients with idiopathic pulmonary fibrosis treated with pirfenidone.

Miura Y, Saito T, Tanaka T, Takoi H, Yatagai Y, Inomata M, Nei T, Saito Y, Gemma A, Azuma A.

Respir Investig. 2018 Jan;56(1):72-79. doi: 10.1016/j.resinv.2017.09.007. Epub 2017 Oct 25.

PMID:
29325685
30.

Prognostic Factors in the Acute Exacerbation of Idiopathic Pulmonary Fibrosis: A Retrospective Single-center Study.

Atsumi K, Saito Y, Kuse N, Kobayashi K, Tanaka T, Kashiwada T, Inomata M, Kokuho N, Hayashi H, Kamio K, Fujita K, Abe S, Azuma A, Kubota K, Gemma A.

Intern Med. 2018 Mar 1;57(5):655-661. doi: 10.2169/internalmedicine.9331-17. Epub 2017 Nov 20.

31.

CRISPR/Cas9-mediated targeted mutagenesis in grape.

Nakajima I, Ban Y, Azuma A, Onoue N, Moriguchi T, Yamamoto T, Toki S, Endo M.

PLoS One. 2017 May 18;12(5):e0177966. doi: 10.1371/journal.pone.0177966. eCollection 2017.

32.

Cyclic mechanical stretch-induced oxidative stress occurs via a NOX-dependent mechanism in type II alveolar epithelial cells.

Tanaka T, Saito Y, Matsuda K, Kamio K, Abe S, Kubota K, Azuma A, Gemma A.

Respir Physiol Neurobiol. 2017 Aug;242:108-116. doi: 10.1016/j.resp.2017.04.007. Epub 2017 Apr 22.

PMID:
28442445
33.

Granuloma-forming interstitial pneumonia induced by nivolumab: a possible immune-related adverse event of the lung.

Kashiwada T, Saito Y, Minegishi Y, Kokuho N, Takahashi A, Takahashi S, Atsumi K, Seike M, Azuma A, Kubota K, Terasaki Y, Gemma A.

Int Cancer Conf J. 2017 Apr 4;6(3):131-134. doi: 10.1007/s13691-017-0291-0. eCollection 2017 Jul.

34.

XPLN is modulated by HDAC inhibitors and negatively regulates SPARC expression by targeting mTORC2 in human lung fibroblasts.

Kamio K, Azuma A, Usuki J, Matsuda K, Inomata M, Nishijima N, Itakura S, Hayashi H, Kashiwada T, Kokuho N, Atsumi K, Yamaguchi T, Fujita K, Saito Y, Abe S, Kubota K, Gemma A.

Pulm Pharmacol Ther. 2017 Jun;44:61-69. doi: 10.1016/j.pupt.2017.03.003. Epub 2017 Mar 14.

PMID:
28315487
35.

Nrf2 Regulates the Risk of a Diesel Exhaust Inhalation-Induced Immune Response during Bleomycin Lung Injury and Fibrosis in Mice.

Li YJ, Shimizu T, Shinkai Y, Hirata Y, Inagaki H, Takeda K, Azuma A, Yamamoto M, Kawada T.

Int J Mol Sci. 2017 Mar 17;18(3). pii: E649. doi: 10.3390/ijms18030649.

36.

Safety management of treatment with nintedanib in clinical practice of IPF.

Azuma A.

Respir Investig. 2017 Jan;55(1):1. doi: 10.1016/j.resinv.2016.12.001. No abstract available.

37.

Nintedanib in Japanese patients with idiopathic pulmonary fibrosis: A subgroup analysis of the INPULSIS® randomized trials.

Azuma A, Taniguchi H, Inoue Y, Kondoh Y, Ogura T, Homma S, Fujimoto T, Sakamoto W, Sugiyama Y, Nukiwa T.

Respirology. 2017 May;22(4):750-757. doi: 10.1111/resp.12960. Epub 2016 Dec 20.

PMID:
27997064
38.

Idiopathic Pulmonary Fibrosis: Treatment and Prognosis.

Fujimoto H, Kobayashi T, Azuma A.

Clin Med Insights Circ Respir Pulm Med. 2016 Dec 8;9(Suppl 1):179-185. eCollection 2015. Review.

39.

An exploratory trial of intravenous immunoglobulin therapy for idiopathic pulmonary fibrosis: a preliminary multicenter report.

Enomoto N, Chida K, Suda T, Kaida Y, Taniguchi M, Azuma A, Hayashi H, Ogura T, Kitamura H, Yamaguchi O, Ando M, Sato A, Kudo S.

Clin Respir J. 2016 Nov;10(6):746-755. doi: 10.1111/crj.12281. Epub 2015 Mar 19.

PMID:
25689162
40.

Pirfenidone exerts a suppressive effect on CCL18 expression in U937-derived macrophages partly by inhibiting STAT6 phosphorylation.

Saito Y, Azuma A, Matsuda K, Kamio K, Abe S, Gemma A.

Immunopharmacol Immunotoxicol. 2016 Dec;38(6):464-471. doi: 10.1080/08923973.2016.1247852. Epub 2016 Oct 27.

PMID:
27788604
41.

Long-term efficacy of macrolide treatment in idiopathic pulmonary fibrosis: a retrospective analysis.

Kuse N, Abe S, Hayashi H, Kamio K, Saito Y, Usuki J, Azuma A, Kudoh S, Gemma A.

Sarcoidosis Vasc Diffuse Lung Dis. 2016 Oct 7;33(3):242-246.

PMID:
27758989
42.

The photomorphogenic factors UV-B RECEPTOR 1, ELONGATED HYPOCOTYL 5, and HY5 HOMOLOGUE are part of the UV-B signalling pathway in grapevine and mediate flavonol accumulation in response to the environment.

Loyola R, Herrera D, Mas A, Wong DC, Höll J, Cavallini E, Amato A, Azuma A, Ziegler T, Aquea F, Castellarin SD, Bogs J, Tornielli GB, Peña-Neira A, Czemmel S, Alcalde JA, Matus JT, Arce-Johnson P.

J Exp Bot. 2016 Oct;67(18):5429-5445. Epub 2016 Aug 19.

43.

A phase II trial evaluating the efficacy and safety of perioperative pirfenidone for prevention of acute exacerbation of idiopathic pulmonary fibrosis in lung cancer patients undergoing pulmonary resection: West Japan Oncology Group 6711 L (PEOPLE Study).

Iwata T, Yoshino I, Yoshida S, Ikeda N, Tsuboi M, Asato Y, Katakami N, Sakamoto K, Yamashita Y, Okami J, Mitsudomi T, Yamashita M, Yokouchi H, Okubo K, Okada M, Takenoyama M, Chida M, Tomii K, Matsuura M, Azuma A, Iwasawa T, Kuwano K, Sakai S, Hiroshima K, Fukuoka J, Yoshimura K, Tada H, Nakagawa K, Nakanishi Y; West Japan Oncology Group.

Respir Res. 2016 Jul 22;17(1):90. doi: 10.1186/s12931-016-0398-4.

44.

Subgroup analysis of Asian patients in the INPULSIS® trials of nintedanib in idiopathic pulmonary fibrosis.

Taniguchi H, Xu Z, Azuma A, Inoue Y, Li H, Fujimoto T, Bailes Z, Schlenker-Herceg R, Kim DS.

Respirology. 2016 Nov;21(8):1425-1430. doi: 10.1111/resp.12852. Epub 2016 Jul 11.

45.

Cytotoxic actions of 2,2-dibromo-3-nitrilopropionamide, a biocide in hydraulic fracturing fluids, on rat thymocytes.

Ishikawa M, Muraguchi R, Azuma A, Nawata S, Miya M, Katsuura T, Naito T, Oyama Y.

Toxicol Res (Camb). 2016 Jun 21;5(5):1329-1334. doi: 10.1039/c6tx00027d. eCollection 2016 Sep 1.

46.

[The Latest Information on Respiratory Disease Management. Topics: III. New Treatment of Idiopathic Pulmonary Fibrosis].

Kashiwada T, Azuma A.

Nihon Naika Gakkai Zasshi. 2016 Jun;105(6):970-6. Japanese. No abstract available.

PMID:
30168687
47.

Context Dependent Effect of Landscape on the Occurrence of an Apex Predator across Different Climate Regions.

Fujita G, Azuma A, Nonaka J, Sakai Y, Sakai H, Iseki F, Itaya H, Fukasawa K, Miyashita T.

PLoS One. 2016 Apr 28;11(4):e0153722. doi: 10.1371/journal.pone.0153722. eCollection 2016.

48.

COPD advances in left ventricular diastolic dysfunction.

Kubota Y, Asai K, Murai K, Tsukada YT, Hayashi H, Saito Y, Azuma A, Gemma A, Shimizu W.

Int J Chron Obstruct Pulmon Dis. 2016 Mar 29;11:649-55. doi: 10.2147/COPD.S101082. eCollection 2016.

49.

Pulmonary mucosa-associated lymphoid tissue lymphoma associated with pulmonary sarcoidosis: a case report and literature review.

Kokuho N, Terasaki Y, Urushiyama H, Terasaki M, Kunugi S, Morimoto T, Azuma A, Usuda J, Gemma A, Eishi Y, Shimizu A.

Hum Pathol. 2016 May;51:57-63. doi: 10.1016/j.humpath.2015.12.019. Epub 2016 Jan 14. Review.

PMID:
27067783
50.

An efficient method for the preparation of preferentially heterodimerized recombinant S100A8/A9 coexpressed in Escherichia coli.

Futami J, Atago Y, Azuma A, Putranto EW, Kinoshita R, Murata H, Sakaguchi M.

Biochem Biophys Rep. 2016 Mar 19;6:94-100. doi: 10.1016/j.bbrep.2016.03.009. eCollection 2016 Jul.

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