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Items: 1 to 50 of 202

1.

DNA-Methylation-Caused Downregulation of miR-30 Contributes to the High Expression of XPO1 and the Aggressive Growth of Tumors in Pancreatic Ductal Adenocarcinoma.

Azmi AS, Li Y, Aboukameel A, Muqbil I, Philip PA, Mohammad RM.

Cancers (Basel). 2019 Aug 2;11(8). pii: E1101. doi: 10.3390/cancers11081101.

2.

Sclerostin as Regulatory Molecule in Vascular Media Calcification and the Bone-Vascular Axis.

De Maré A, Maudsley S, Azmi A, Hendrickx JO, Opdebeeck B, Neven E, D'Haese PC, Verhulst A.

Toxins (Basel). 2019 Jul 21;11(7). pii: E428. doi: 10.3390/toxins11070428.

3.

The Influence of Modernization and Disease on the Gastric Microbiome of Orang Asli, Myanmars and Modern Malaysians.

Chua EG, Loke MF, Gunaletchumy SP, Gan HM, Thevakumar K, Tay CY, Young S, Aye TT, Maw WW, Aye MM, Leow AH, Azmi AN, Kalimuthu SG, Dahlan HMABD, Goh KL, Vadivelu J.

Microorganisms. 2019 Jun 14;7(6). pii: E174. doi: 10.3390/microorganisms7060174.

4.

KRASG12C inhibitors on the horizon.

Cagir A, Azmi AS.

Future Med Chem. 2019 May;11(9):923-925. doi: 10.4155/fmc-2018-0304. Epub 2019 May 29. No abstract available.

5.

Enhanced Flexibility of Biodegradable Polylactic Acid/Starch Blends Using Epoxidized Palm Oil as Plasticizer.

Awale RJ, Ali FB, Azmi AS, Puad NIM, Anuar H, Hassan A.

Polymers (Basel). 2018 Sep 2;10(9). pii: E977. doi: 10.3390/polym10090977.

6.

Indoxyl Sulfate and p-Cresyl Sulfate Promote Vascular Calcification and Associate with Glucose Intolerance.

Opdebeeck B, Maudsley S, Azmi A, De Maré A, De Leger W, Meijers B, Verhulst A, Evenepoel P, D'Haese PC, Neven E.

J Am Soc Nephrol. 2019 May;30(5):751-766. doi: 10.1681/ASN.2018060609. Epub 2019 Apr 2.

PMID:
30940651
7.

Ras and exosome signaling.

Sexton RE, Mpilla G, Kim S, Philip PA, Azmi AS.

Semin Cancer Biol. 2019 Feb;54:131-137. doi: 10.1016/j.semcancer.2019.02.004. Epub 2019 Feb 12. Review.

PMID:
30769101
8.

CodSeqGen: A tool for generating synonymous coding sequences with desired GC-contents.

Al-Ssulami AM, Azmi AM, Hussain M.

Genomics. 2019 Feb 6. pii: S0888-7543(18)30608-6. doi: 10.1016/j.ygeno.2019.02.002. [Epub ahead of print]

PMID:
30738198
9.

Pharmacotherapeutic strategies for treating pancreatic cancer: advances and challenges.

Diab M, Azmi A, Mohammad R, Philip PA.

Expert Opin Pharmacother. 2019 Apr;20(5):535-546. doi: 10.1080/14656566.2018.1561869. Epub 2018 Dec 28. Review.

PMID:
30592647
10.

miRNA and Gene Expression in Pancreatic Ductal Adenocarcinoma.

Tesfaye AA, Azmi AS, Philip PA.

Am J Pathol. 2019 Jan;189(1):58-70. doi: 10.1016/j.ajpath.2018.10.005. Review.

PMID:
30558723
11.

Down-regulation of AR splice variants through XPO1 suppression contributes to the inhibition of prostate cancer progression.

Aboukameel A, Muqbil I, Baloglu E, Senapedis W, Landesman Y, Argueta C, Kauffman M, Chang H, Kashyap T, Shacham S, Neggers JE, Daelemans D, Heath EI, Azmi AS.

Oncotarget. 2018 Oct 19;9(82):35327-35342. doi: 10.18632/oncotarget.26239. eCollection 2018 Oct 19.

12.

Image-guided phenotyping of ovariectomized mice: altered functional connectivity, cognition, myelination, and dopaminergic functionality.

Anckaerts C, van Gastel J, Leysen V, Hinz R, Azmi A, Simoens P, Shah D, Kara F, Langbeen A, Bols P, Laloux C, Prevot V, Verhoye M, Maudsley S, Van der Linden A.

Neurobiol Aging. 2019 Feb;74:77-89. doi: 10.1016/j.neurobiolaging.2018.10.012. Epub 2018 Oct 17.

PMID:
30439596
13.

Nuclear export mechanisms of circular RNAs: size does matter.

Azmi AS.

Noncoding RNA Investig. 2018 Sep;2. pii: 52. doi: 10.21037/ncri.2018.08.03. Epub 2018 Sep 14. No abstract available.

14.

Optimizing first line 7-day standard triple therapy for Helicobacter pylori eradication: Prolonging treatment or adding bismuth: which is better?

Leow AH, Azmi AN, Loke MF, Vadivelu J, Graham DY, Goh KL.

J Dig Dis. 2018 Nov;19(11):674-677. doi: 10.1111/1751-2980.12679. Epub 2018 Nov 8.

PMID:
30307122
15.

Neuroendoscopy for post-infective hydrocephalus in children.

Deopujari CE, Padayachy L, Azmi A, Figaji A, Samantray SK.

Childs Nerv Syst. 2018 Oct;34(10):1905-1914. doi: 10.1007/s00381-018-3901-z. Epub 2018 Aug 11.

PMID:
30099619
16.

Some chinks in RAS armor.

Azmi AS.

Semin Cancer Biol. 2019 Feb;54:iii-iv. doi: 10.1016/j.semcancer.2018.08.005. Epub 2018 Aug 6. No abstract available.

PMID:
30092255
17.

Nuclear Export Inhibition for Pancreatic Cancer Therapy.

Muqbil I, Azmi AS, Mohammad RM.

Cancers (Basel). 2018 May 7;10(5). pii: E138. doi: 10.3390/cancers10050138. Review.

18.

Paclitaxel and di-fluorinated curcumin loaded in albumin nanoparticles for targeted synergistic combination therapy of ovarian and cervical cancers.

Gawde KA, Sau S, Tatiparti K, Kashaw SK, Mehrmohammadi M, Azmi AS, Iyer AK.

Colloids Surf B Biointerfaces. 2018 Jul 1;167:8-19. doi: 10.1016/j.colsurfb.2018.03.046. Epub 2018 Mar 28.

PMID:
29625422
19.

Retraction notice to "Notch-1 induces Epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells".

Bao B, Wang Z, Ali S, Kong D, Li Y, Ahmad A, Banerjee S, Azmi AS, Miele L, Sarkar FH.

Cancer Lett. 2018 Jun 1;423:153. doi: 10.1016/j.canlet.2018.03.020.

20.

An atlas to aid delineation of para-aortic lymph node region in cervical cancer: Design and validation of contouring guidelines.

Keenan LG, Rock K, Azmi A, Salib O, Gillham C, McArdle O.

Radiother Oncol. 2018 Jun;127(3):417-422. doi: 10.1016/j.radonc.2018.02.013. Epub 2018 Mar 6.

PMID:
29523410
21.

PFN2 and GAMT as common molecular determinants of axonal Charcot-Marie-Tooth disease.

Juneja M, Azmi A, Baets J, Roos A, Jennings MJ, Saveri P, Pisciotta C, Bernard-Marissal N, Schneider BL, Verfaillie C, Chrast R, Seeman P, Hahn AF, de Jonghe P, Maudsley S, Horvath R, Pareyson D, Timmerman V.

J Neurol Neurosurg Psychiatry. 2018 Aug;89(8):870-878. doi: 10.1136/jnnp-2017-317562. Epub 2018 Feb 15.

PMID:
29449460
22.

Effect of Surface Treatment on Enamel Cracks After Orthodontic Bracket Debonding: Er,Cr:YSGG Laser-Etching Versus Acid-Etching.

Ghaffari H, Mirhashemi A, Baherimoghadam T, Azmi A, Rasooli R.

J Dent (Tehran). 2017 Sep;14(5):259-266.

23.

The evolution into personalized therapies in pancreatic ductal adenocarcinoma: challenges and opportunities.

Tesfaye AA, Kamgar M, Azmi A, Philip PA.

Expert Rev Anticancer Ther. 2018 Feb;18(2):131-148. doi: 10.1080/14737140.2018.1417844. Epub 2017 Dec 19. Review.

24.

Rho GTPase effectors and NAD metabolism in cancer immune suppression.

Chaker M, Minden A, Chen S, Weiss RH, Chini EN, Mahipal A, Azmi AS.

Expert Opin Ther Targets. 2018 Jan;22(1):9-17. doi: 10.1080/14728222.2018.1413091. Epub 2017 Dec 10. Review.

25.

Exportin 1 (XPO1) inhibition leads to restoration of tumor suppressor miR-145 and consequent suppression of pancreatic cancer cell proliferation and migration.

Azmi AS, Li Y, Muqbil I, Aboukameel A, Senapedis W, Baloglu E, Landesman Y, Shacham S, Kauffman MG, Philip PA, Mohammad RM.

Oncotarget. 2017 Jul 17;8(47):82144-82155. doi: 10.18632/oncotarget.19285. eCollection 2017 Oct 10.

26.

A rare case of methicillin resistant Staphylococcus aureus (MRSA) cerebral abscess secondary to conjunctivitis.

Gan YK, Azmi AZ, Ghani SA, Samsudin A.

Med J Malaysia. 2017 Jun;72(3):197-198.

27.

Targeting Rho GTPase effector p21 activated kinase 4 (PAK4) suppresses p-Bad-microRNA drug resistance axis leading to inhibition of pancreatic ductal adenocarcinoma proliferation.

Mohammad RM, Li Y, Muqbil I, Aboukameel A, Senapedis W, Baloglu E, Landesman Y, Philip PA, Azmi AS.

Small GTPases. 2019 Sep;10(5):367-377. doi: 10.1080/21541248.2017.1329694. Epub 2017 Jun 23.

PMID:
28641032
28.

Targeting ERK enhances the cytotoxic effect of the novel PI3K and mTOR dual inhibitor VS-5584 in preclinical models of pancreatic cancer.

Ning C, Liang M, Liu S, Wang G, Edwards H, Xia Y, Polin L, Dyson G, Taub JW, Mohammad RM, Azmi AS, Zhao L, Ge Y.

Oncotarget. 2017 Jul 4;8(27):44295-44311. doi: 10.18632/oncotarget.17869.

29.

An efficient method for significant motifs discovery from multiple DNA sequences.

Al-Ssulami AM, Azmi AM, Mathkour H.

J Bioinform Comput Biol. 2017 Aug;15(4):1750014. doi: 10.1142/S0219720017500147. Epub 2017 May 11.

PMID:
28571483
30.

Altered learning, memory, and social behavior in type 1 taste receptor subunit 3 knock-out mice are associated with neuronal dysfunction.

Martin B, Wang R, Cong WN, Daimon CM, Wu WW, Ni B, Becker KG, Lehrmann E, Wood WH 3rd, Zhang Y, Etienne H, van Gastel J, Azmi A, Janssens J, Maudsley S.

J Biol Chem. 2017 Jul 7;292(27):11508-11530. doi: 10.1074/jbc.M116.773820. Epub 2017 May 18.

31.

Global Fecal and Plasma Metabolic Dynamics Related to Helicobacter pylori Eradication.

Yap TW, Leow AH, Azmi AN, Callahan DL, Perez-Perez GI, Loke MF, Goh KL, Vadivelu J.

Front Microbiol. 2017 Mar 30;8:536. doi: 10.3389/fmicb.2017.00536. eCollection 2017.

32.

Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption.

Siddiqui S, Lustig A, Carter A, Sankar M, Daimon CM, Premont RT, Etienne H, van Gastel J, Azmi A, Janssens J, Becker KG, Zhang Y, Wood W, Lehrmann E, Martin JG, Martin B, Taub DD, Maudsley S.

Aging (Albany NY). 2017 Mar 4;9(3):706-740. doi: 10.18632/aging.101185.

33.

Development of Precision Small-Molecule Proneurotrophic Therapies for Neurodegenerative Diseases.

Janssens J, Lu D, Ni B, Chadwick W, Siddiqui S, Azmi A, Etienne H, Jushaj A, van Gastel J, Martin B, Maudsley S.

Vitam Horm. 2017;104:263-311. doi: 10.1016/bs.vh.2016.10.006. Epub 2016 Nov 29. Review.

PMID:
28215298
34.

Gastric Metastasis from Hepatocellular Carcinoma: A Rare Manifestation.

Abdul Hakim MS, Azmi AN, Jayalakshmi P, Mahadeva S.

J Gastrointest Cancer. 2018 Sep;49(3):346-348. doi: 10.1007/s12029-016-9913-6. No abstract available.

PMID:
28066868
35.

Novel p21-Activated Kinase 4 (PAK4) Allosteric Modulators Overcome Drug Resistance and Stemness in Pancreatic Ductal Adenocarcinoma.

Aboukameel A, Muqbil I, Senapedis W, Baloglu E, Landesman Y, Shacham S, Kauffman M, Philip PA, Mohammad RM, Azmi AS.

Mol Cancer Ther. 2017 Jan;16(1):76-87. doi: 10.1158/1535-7163.MCT-16-0205. Epub 2016 Nov 15.

36.

Targeting Cancer at the Nuclear Pore.

Azmi AS, Mohammad RM.

J Clin Oncol. 2016 Dec;34(34):4180-4182. Epub 2016 Oct 23. No abstract available.

PMID:
27863200
37.

Anti-tumor activity of selective inhibitor of nuclear export (SINE) compounds, is enhanced in non-Hodgkin lymphoma through combination with mTOR inhibitor and dexamethasone.

Muqbil I, Aboukameel A, Elloul S, Carlson R, Senapedis W, Baloglu E, Kauffman M, Shacham S, Bhutani D, Zonder J, Azmi AS, Mohammad RM.

Cancer Lett. 2016 Dec 28;383(2):309-317. doi: 10.1016/j.canlet.2016.09.016. Epub 2016 Sep 28.

38.

Selinexor, a Selective Inhibitor of Nuclear Export (SINE) compound, acts through NF-κB deactivation and combines with proteasome inhibitors to synergistically induce tumor cell death.

Kashyap T, Argueta C, Aboukameel A, Unger TJ, Klebanov B, Mohammad RM, Muqbil I, Azmi AS, Drolen C, Senapedis W, Lee M, Kauffman M, Shacham S, Landesman Y.

Oncotarget. 2016 Nov 29;7(48):78883-78895. doi: 10.18632/oncotarget.12428.

39.

Fluorescence multispectral imaging-based diagnostic system for atherosclerosis.

Ho CS, Horiuchi T, Taniguchi H, Umetsu A, Hagisawa K, Iwaya K, Nakai K, Azmi A, Zulaziz N, Azhim A, Shinomiya N, Morimoto Y.

Biomed Eng Online. 2016 Aug 20;15(1):98. doi: 10.1186/s12938-016-0220-z.

40.

The Role of microRNAs in the Diagnosis and Treatment of Pancreatic Adenocarcinoma.

Diab M, Muqbil I, Mohammad RM, Azmi AS, Philip PA.

J Clin Med. 2016 Jun 16;5(6). pii: E59. doi: 10.3390/jcm5060059. Review.

41.

Helicobacter pylori Eradication Causes Perturbation of the Human Gut Microbiome in Young Adults.

Yap TW, Gan HM, Lee YP, Leow AH, Azmi AN, Francois F, Perez-Perez GI, Loke MF, Goh KL, Vadivelu J.

PLoS One. 2016 Mar 18;11(3):e0151893. doi: 10.1371/journal.pone.0151893. eCollection 2016.

42.

Split-dose low-volume bowel preparation, a feasible option for preparation for colonoscopy.

Azmi AN, Chan WK, Mahadeva S, Goh KL.

Endoscopy. 2016 Feb;48(2):197. doi: 10.1055/s-0034-1393347. Epub 2016 Jan 28. No abstract available.

PMID:
26820080
43.

F-BOX proteins in cancer cachexia and muscle wasting: Emerging regulators and therapeutic opportunities.

Sukari A, Muqbil I, Mohammad RM, Philip PA, Azmi AS.

Semin Cancer Biol. 2016 Feb;36:95-104. doi: 10.1016/j.semcancer.2016.01.002. Epub 2016 Jan 21. Review.

44.

Opening a Pandora's (F)-box in cancer.

Azmi AS.

Semin Cancer Biol. 2016 Feb;36:1-2. doi: 10.1016/j.semcancer.2015.12.001. Epub 2015 Dec 17. No abstract available.

PMID:
26706999
45.

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

Block KI, Gyllenhaal C, Lowe L, Amedei A, Amin ARMR, Amin A, Aquilano K, Arbiser J, Arreola A, Arzumanyan A, Ashraf SS, Azmi AS, Benencia F, Bhakta D, Bilsland A, Bishayee A, Blain SW, Block PB, Boosani CS, Carey TE, Carnero A, Carotenuto M, Casey SC, Chakrabarti M, Chaturvedi R, Chen GZ, Chen H, Chen S, Chen YC, Choi BK, Ciriolo MR, Coley HM, Collins AR, Connell M, Crawford S, Curran CS, Dabrosin C, Damia G, Dasgupta S, DeBerardinis RJ, Decker WK, Dhawan P, Diehl AME, Dong JT, Dou QP, Drew JE, Elkord E, El-Rayes B, Feitelson MA, Felsher DW, Ferguson LR, Fimognari C, Firestone GL, Frezza C, Fujii H, Fuster MM, Generali D, Georgakilas AG, Gieseler F, Gilbertson M, Green MF, Grue B, Guha G, Halicka D, Helferich WG, Heneberg P, Hentosh P, Hirschey MD, Hofseth LJ, Holcombe RF, Honoki K, Hsu HY, Huang GS, Jensen LD, Jiang WG, Jones LW, Karpowicz PA, Keith WN, Kerkar SP, Khan GN, Khatami M, Ko YH, Kucuk O, Kulathinal RJ, Kumar NB, Kwon BS, Le A, Lea MA, Lee HY, Lichtor T, Lin LT, Locasale JW, Lokeshwar BL, Longo VD, Lyssiotis CA, MacKenzie KL, Malhotra M, Marino M, Martinez-Chantar ML, Matheu A, Maxwell C, McDonnell E, Meeker AK, Mehrmohamadi M, Mehta K, Michelotti GA, Mohammad RM, Mohammed SI, Morre DJ, Muralidhar V, Muqbil I, Murphy MP, Nagaraju GP, Nahta R, Niccolai E, Nowsheen S, Panis C, Pantano F, Parslow VR, Pawelec G, Pedersen PL, Poore B, Poudyal D, Prakash S, Prince M, Raffaghello L, Rathmell JC, Rathmell WK, Ray SK, Reichrath J, Rezazadeh S, Ribatti D, Ricciardiello L, Robey RB, Rodier F, Rupasinghe HPV, Russo GL, Ryan EP, Samadi AK, Sanchez-Garcia I, Sanders AJ, Santini D, Sarkar M, Sasada T, Saxena NK, Shackelford RE, Shantha Kumara HMC, Sharma D, Shin DM, Sidransky D, Siegelin MD, Signori E, Singh N, Sivanand S, Sliva D, Smythe C, Spagnuolo C, Stafforini DM, Stagg J, Subbarayan PR, Sundin T, Talib WH, Thompson SK, Tran PT, Ungefroren H, Vander Heiden MG, Venkateswaran V, Vinay DS, Vlachostergios PJ, Wang Z, Wellen KE, Whelan RL, Yang ES, Yang H, Yang X, Yaswen P, Yedjou C, Yin X, Zhu J, Zollo M.

Semin Cancer Biol. 2015 Dec;35 Suppl:S276-S304. doi: 10.1016/j.semcancer.2015.09.007. Review.

46.

Targeting the Nuclear Export Protein XPO1/CRM1 Reverses Epithelial to Mesenchymal Transition.

Azmi AS, Muqbil I, Wu J, Aboukameel A, Senapedis W, Baloglu E, Bollig-Fischer A, Dyson G, Kauffman M, Landesman Y, Shacham S, Philip PA, Mohammad RM.

Sci Rep. 2015 Nov 5;5:16077. doi: 10.1038/srep16077.

47.

Recessive mutations in SLC13A5 result in a loss of citrate transport and cause neonatal epilepsy, developmental delay and teeth hypoplasia.

Hardies K, de Kovel CG, Weckhuysen S, Asselbergh B, Geuens T, Deconinck T, Azmi A, May P, Brilstra E, Becker F, Barisic N, Craiu D, Braun KP, Lal D, Thiele H, Schubert J, Weber Y, van 't Slot R, Nürnberg P, Balling R, Timmerman V, Lerche H, Maudsley S, Helbig I, Suls A, Koeleman BP, De Jonghe P; autosomal recessive working group of the EuroEPINOMICS RES Consortium.

Brain. 2015 Nov;138(Pt 11):3238-50. doi: 10.1093/brain/awv263. Epub 2015 Sep 17.

PMID:
26384929
48.

Changes in Metabolic Hormones in Malaysian Young Adults following Helicobacter pylori Eradication.

Yap TW, Leow AH, Azmi AN, Francois F, Perez-Perez GI, Blaser MJ, Poh BH, Loke MF, Goh KL, Vadivelu J.

PLoS One. 2015 Aug 20;10(8):e0135771. doi: 10.1371/journal.pone.0135771. eCollection 2015.

49.

Sustained complete remission of advanced hepatocellular carcinoma with sorafenib therapy.

Azmi AN, Chan WK, Goh KL.

J Dig Dis. 2015 Sep;16(9):537-40. doi: 10.1111/1751-2980.12270. No abstract available.

PMID:
26147446
50.

A multi-targeted approach to suppress tumor-promoting inflammation.

Samadi AK, Bilsland A, Georgakilas AG, Amedei A, Amin A, Bishayee A, Azmi AS, Lokeshwar BL, Grue B, Panis C, Boosani CS, Poudyal D, Stafforini DM, Bhakta D, Niccolai E, Guha G, Vasantha Rupasinghe HP, Fujii H, Honoki K, Mehta K, Aquilano K, Lowe L, Hofseth LJ, Ricciardiello L, Ciriolo MR, Singh N, Whelan RL, Chaturvedi R, Ashraf SS, Shantha Kumara HMC, Nowsheen S, Mohammed SI, Keith WN, Helferich WG, Yang X.

Semin Cancer Biol. 2015 Dec;35 Suppl:S151-S184. doi: 10.1016/j.semcancer.2015.03.006. Epub 2015 May 5. Review.

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