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The novel anti-androgen candidate galeterone targets deubiquitinating enzymes, USP12 and USP46, to control prostate cancer growth and survival.

McClurg UL, Azizyan M, Dransfield DT, Namdev N, Chit NCTH, Nakjang S, Robson CN.

Oncotarget. 2018 May 18;9(38):24992-25007. doi: 10.18632/oncotarget.25167. eCollection 2018 May 18.


Molecular mechanism of the TP53-MDM2-AR-AKT signalling network regulation by USP12.

McClurg UL, Chit NCTH, Azizyan M, Edwards J, Nabbi A, Riabowol KT, Nakjang S, McCracken SR, Robson CN.

Oncogene. 2018 Aug;37(34):4679-4691. doi: 10.1038/s41388-018-0283-3. Epub 2018 May 14.


RNA design rules from a massive open laboratory.

Lee J, Kladwang W, Lee M, Cantu D, Azizyan M, Kim H, Limpaecher A, Yoon S, Treuille A, Das R; EteRNA Participants.

Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2122-7. doi: 10.1073/pnas.1313039111. Epub 2014 Jan 27. Erratum in: Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):E5900. Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):E490.


Antibody-induced nonapoptotic cell death in human lymphoma and leukemia cells is mediated through a novel reactive oxygen species-dependent pathway.

Honeychurch J, Alduaij W, Azizyan M, Cheadle EJ, Pelicano H, Ivanov A, Huang P, Cragg MS, Illidge TM.

Blood. 2012 Apr 12;119(15):3523-33. doi: 10.1182/blood-2011-12-395541. Epub 2012 Feb 21.

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