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Items: 28


An isogenic hiPSC-derived BBB-on-a-chip.

Motallebnejad P, Thomas A, Swisher SL, Azarin SM.

Biomicrofluidics. 2019 Nov 22;13(6):064119. doi: 10.1063/1.5123476. eCollection 2019 Nov.


Adhesive thermosensitive gels for local delivery of viral vectors.

Caronia JM, Sorensen DW, Leslie HM, van Berlo JH, Azarin SM.

Biotechnol Bioeng. 2019 Sep;116(9):2353-2363. doi: 10.1002/bit.27007. Epub 2019 May 20.


Engineering T cell response to cancer antigens by choice of focal therapeutic conditions.

Shao Q, O'Flanagan S, Lam T, Roy P, Pelaez F, Burbach BJ, Azarin SM, Shimizu Y, Bischof JC.

Int J Hyperthermia. 2019;36(1):130-138. doi: 10.1080/02656736.2018.1539253. Epub 2019 Jan 24.


A facile in vitro platform to study cancer cell dormancy under hypoxic microenvironments using CoCl2.

Lee HR, Leslie F, Azarin SM.

J Biol Eng. 2018 Aug 3;12:12. doi: 10.1186/s13036-018-0106-7. eCollection 2018.


Modeling and rescue of defective blood-brain barrier function of induced brain microvascular endothelial cells from childhood cerebral adrenoleukodystrophy patients.

Lee CAA, Seo HS, Armien AG, Bates FS, Tolar J, Azarin SM.

Fluids Barriers CNS. 2018 Apr 4;15(1):9. doi: 10.1186/s12987-018-0094-5.


Biomaterial scaffolds for non-invasive focal hyperthermia as a potential tool to ablate metastatic cancer cells.

Pelaez F, Manuchehrabadi N, Roy P, Natesan H, Wang Y, Racila E, Fong H, Zeng K, Silbaugh AM, Bischof JC, Azarin SM.

Biomaterials. 2018 Jun;166:27-37. doi: 10.1016/j.biomaterials.2018.02.048. Epub 2018 Feb 28.


Biomaterial Scaffolds as Pre-metastatic Niche Mimics Systemically Alter the Primary Tumor and Tumor Microenvironment.

Aguado BA, Hartfield RM, Bushnell GG, Decker JT, Azarin SM, Nanavati D, Schipma MJ, Rao SS, Oakes RS, Zhang Y, Jeruss JS, Shea LD.

Adv Healthc Mater. 2018 May;7(10):e1700903. doi: 10.1002/adhm.201700903. Epub 2018 Mar 9.


Freezing Responses in DMSO-Based Cryopreservation of Human iPS Cells: Aggregates Versus Single Cells.

Li R, Yu G, Azarin SM, Hubel A.

Tissue Eng Part C Methods. 2018 May;24(5):289-299. doi: 10.1089/ten.TEC.2017.0531. Epub 2018 Mar 28.


Enhanced Survival with Implantable Scaffolds That Capture Metastatic Breast Cancer Cells In Vivo.

Rao SS, Bushnell GG, Azarin SM, Spicer G, Aguado BA, Stoehr JR, Jiang EJ, Backman V, Shea LD, Jeruss JS.

Cancer Res. 2016 Sep 15;76(18):5209-18. doi: 10.1158/0008-5472.CAN-15-2106.


Detection of extracellular matrix modification in cancer models with inverse spectroscopic optical coherence tomography.

Spicer GL, Azarin SM, Yi J, Young ST, Ellis R, Bauer GM, Shea LD, Backman V.

Phys Med Biol. 2016 Oct 7;61(19):6892-6904. Epub 2016 Sep 12.


Extracellular matrix mediators of metastatic cell colonization characterized using scaffold mimics of the pre-metastatic niche.

Aguado BA, Caffe JR, Nanavati D, Rao SS, Bushnell GG, Azarin SM, Shea LD.

Acta Biomater. 2016 Mar;33:13-24. doi: 10.1016/j.actbio.2016.01.043. Epub 2016 Feb 1.


Secretome identification of immune cell factors mediating metastatic cell homing.

Aguado BA, Wu JJ, Azarin SM, Nanavati D, Rao SS, Bushnell GG, Medicherla CB, Shea LD.

Sci Rep. 2015 Dec 4;5:17566. doi: 10.1038/srep17566.


In vivo capture and label-free detection of early metastatic cells.

Azarin SM, Yi J, Gower RM, Aguado BA, Sullivan ME, Goodman AG, Jiang EJ, Rao SS, Ren Y, Tucker SL, Backman V, Jeruss JS, Shea LD.

Nat Commun. 2015 Sep 8;6:8094. doi: 10.1038/ncomms9094.


Spatially resolved optical and ultrastructural properties of colorectal and pancreatic field carcinogenesis observed by inverse spectroscopic optical coherence tomography.

Yi J, Radosevich AJ, Stypula-Cyrus Y, Mutyal NN, Azarin SM, Horcher E, Goldberg MJ, Bianchi LK, Bajaj S, Roy HK, Backman V.

J Biomed Opt. 2014 Mar;19(3):36013. doi: 10.1117/1.JBO.19.3.036013.


A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources.

Lippmann ES, Al-Ahmad A, Azarin SM, Palecek SP, Shusta EV.

Sci Rep. 2014 Feb 24;4:4160. doi: 10.1038/srep04160.


Modulation of leukocyte infiltration and phenotype in microporous tissue engineering scaffolds via vector induced IL-10 expression.

Gower RM, Boehler RM, Azarin SM, Ricci CF, Leonard JN, Shea LD.

Biomaterials. 2014 Feb;35(6):2024-31. doi: 10.1016/j.biomaterials.2013.11.036. Epub 2013 Dec 3.


Effects of 3D microwell culture on growth kinetics and metabolism of human embryonic stem cells.

Azarin SM, Larson EA, Almodóvar-Cruz JM, de Pablo JJ, Palecek SP.

Biotechnol Appl Biochem. 2012 Mar-Apr;59(2):88-96. doi: 10.1002/bab.1003. Epub 2012 Feb 23.


Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions.

Lian X, Zhang J, Azarin SM, Zhu K, Hazeltine LB, Bao X, Hsiao C, Kamp TJ, Palecek SP.

Nat Protoc. 2013 Jan;8(1):162-75. doi: 10.1038/nprot.2012.150. Epub 2012 Dec 20.


Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells.

Lippmann ES, Azarin SM, Kay JE, Nessler RA, Wilson HK, Al-Ahmad A, Palecek SP, Shusta EV.

Nat Biotechnol. 2012 Aug;30(8):783-91.


Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling.

Lian X, Hsiao C, Wilson G, Zhu K, Hazeltine LB, Azarin SM, Raval KK, Zhang J, Kamp TJ, Palecek SP.

Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):E1848-57. doi: 10.1073/pnas.1200250109. Epub 2012 May 29.


Modulation of Wnt/β-catenin signaling in human embryonic stem cells using a 3-D microwell array.

Azarin SM, Lian X, Larson EA, Popelka HM, de Pablo JJ, Palecek SP.

Biomaterials. 2012 Mar;33(7):2041-9. doi: 10.1016/j.biomaterials.2011.11.070. Epub 2011 Dec 15.


Fabrication and selective functionalization of amine-reactive polymer multilayers on topographically patterned microwell cell culture arrays.

Broderick AH, Azarin SM, Buck ME, Palecek SP, Lynn DM.

Biomacromolecules. 2011 Jun 13;12(6):1998-2007. doi: 10.1021/bm200296a. Epub 2011 Apr 19.


Matrix revolutions: a trinity of defined substrates for long-term expansion of human ESCs.

Azarin SM, Palecek SP.

Cell Stem Cell. 2010 Jul 2;7(1):7-8. doi: 10.1016/j.stem.2010.06.008.


Development of Scalable Culture Systems for Human Embryonic Stem Cells.

Azarin SM, Palecek SP.

Biochem Eng J. 2010 Feb 15;48(3):378.


The microwell control of embryoid body size in order to regulate cardiac differentiation of human embryonic stem cells.

Mohr JC, Zhang J, Azarin SM, Soerens AG, de Pablo JJ, Thomson JA, Lyons GE, Palecek SP, Kamp TJ.

Biomaterials. 2010 Mar;31(7):1885-93. doi: 10.1016/j.biomaterials.2009.11.033. Epub 2009 Nov 28.


Human embryonic stem cell-derived keratinocytes exhibit an epidermal transcription program and undergo epithelial morphogenesis in engineered tissue constructs.

Metallo CM, Azarin SM, Moses LE, Ji L, de Pablo JJ, Palecek SP.

Tissue Eng Part A. 2010 Jan;16(1):213-23. doi: 10.1089/ten.TEA.2009.0325.


Engineering tissue from human embryonic stem cells.

Metallo CM, Azarin SM, Ji L, de Pablo JJ, Palecek SP.

J Cell Mol Med. 2008 Jun;12(3):709-29. doi: 10.1111/j.1582-4934.2008.00228.x. Epub 2008 Jan 11. Review.


Tumor-targeted gene delivery using molecularly engineered hybrid polymers functionalized with a tumor-homing peptide.

Wood KC, Azarin SM, Arap W, Pasqualini R, Langer R, Hammond PT.

Bioconjug Chem. 2008 Feb;19(2):403-5. doi: 10.1021/bc700408r. Epub 2008 Jan 12.


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