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Items: 1 to 50 of 114

1.

Continuous Positive Airway Pressure Use for Obstructive Sleep Apnea in Acute, Traumatic Tetraplegia.

Graco M, Schembri R, Ross J, Green SE, Booker L, Cistulli PA, Ayas NT, Berlowitz DJ; COSAQ Investigators.

Arch Phys Med Rehabil. 2019 Aug 15. pii: S0003-9993(19)30982-7. doi: 10.1016/j.apmr.2019.07.005. [Epub ahead of print]

PMID:
31421094
2.

Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis.

Benjafield AV, Ayas NT, Eastwood PR, Heinzer R, Ip MSM, Morrell MJ, Nunez CM, Patel SR, Penzel T, Pépin JL, Peppard PE, Sinha S, Tufik S, Valentine K, Malhotra A.

Lancet Respir Med. 2019 Aug;7(8):687-698. doi: 10.1016/S2213-2600(19)30198-5. Epub 2019 Jul 9.

PMID:
31300334
3.

C-Reactive Protein Levels and the Risk of Incident Cardiovascular and Cerebrovascular Events in Patients with Obstructive Sleep Apnea.

Ayas NT, Hirsch Allen AJ, Fox N, Peres B, Mehrtash M, Humphries KH, Jen R, Taylor CM, van Eeden SF.

Lung. 2019 Aug;197(4):459-464. doi: 10.1007/s00408-019-00237-0. Epub 2019 May 14.

PMID:
31089857
4.

The antioxidant α-lipoic acid attenuates intermittent hypoxia-related renal injury in a mouse model of sleep apnea.

Abuyassin B, Badran M, Ayas NT, Laher I.

Sleep. 2019 Jun 11;42(6). pii: zsz066. doi: 10.1093/sleep/zsz066.

PMID:
30880336
5.

Could Adjunctive Pharmacology Mitigate Cardiovascular Consequences of Obstructive Sleep Apnea?

Ayas NT, Foster GE, Shah N, Floras J, Laher I.

Am J Respir Crit Care Med. 2019 Sep 1;200(5):551-555. doi: 10.1164/rccm.201811-2097PP. No abstract available.

PMID:
30875238
6.

Circulating biomarkers to identify cardiometabolic complications in patients with Obstructive Sleep Apnea: A systematic review.

Peres BU, Hirsch Allen AJ, Fox N, Laher I, Hanly P, Skomro R, Almeida F, Ayas NT; Canadian Sleep and Circadian Network.

Sleep Med Rev. 2019 Apr;44:48-57. doi: 10.1016/j.smrv.2018.12.004. Epub 2018 Dec 27.

PMID:
30685729
7.

Adhesion molecule gene variants and plasma protein levels in patients with suspected obstructive sleep apnea.

Sandford AJ, Ha A, Ngan DA, Akhabir L, Saferali A, Fox N, Hirsch Allen AJ, Warby SC, van Eeden SF, Ayas NT.

PLoS One. 2019 Jan 17;14(1):e0210732. doi: 10.1371/journal.pone.0210732. eCollection 2019.

8.

Sleep Study and Oximetry Parameters for Predicting Postoperative Complications in Patients With OSA.

Suen C, Ryan CM, Mubashir T, Ayas NT, Abrahamyan L, Wong J, Mokhlesi B, Chung F.

Chest. 2019 Apr;155(4):855-867. doi: 10.1016/j.chest.2018.09.030. Epub 2018 Oct 22. Review.

9.

Diagnostic accuracy of a two-stage model for detecting obstructive sleep apnoea in chronic tetraplegia.

Graco M, Schembri R, Cross S, Thiyagarajan C, Shafazand S, Ayas NT, Nash MS, Vu VH, Ruehland WR, Chai-Coetzer CL, Rochford P, Churchward T, Green SE, Berlowitz DJ.

Thorax. 2018 Sep;73(9):864-871. doi: 10.1136/thoraxjnl-2017-211131. Epub 2018 May 7.

PMID:
29735608
10.

Addressing challenges with current therapies for obstructive sleep apnea.

Laratta CR, Ayas NT, Povitz M, Pendharkar SR.

CMAJ. 2018 May 7;190(18):E573. doi: 10.1503/cmaj.69278. No abstract available.

11.

Intermittent hypoxia causes histological kidney damage and increases growth factor expression in a mouse model of obstructive sleep apnea.

Abuyassin B, Badran M, Ayas NT, Laher I.

PLoS One. 2018 Feb 1;13(2):e0192084. doi: 10.1371/journal.pone.0192084. eCollection 2018.

12.

Knowledge Gaps in the Perioperative Management of Adults with Obstructive Sleep Apnea and Obesity Hypoventilation Syndrome. An Official American Thoracic Society Workshop Report.

Ayas NT, Laratta CR, Coleman JM, Doufas AG, Eikermann M, Gay PC, Gottlieb DJ, Gurubhagavatula I, Hillman DR, Kaw R, Malhotra A, Mokhlesi B, Morgenthaler TI, Parthasarathy S, Ramachandran SK, Strohl KP, Strollo PJ, Twery MJ, Zee PC, Chung FF; ATS Assembly on Sleep and Respiratory Neurobiology.

Ann Am Thorac Soc. 2018 Feb;15(2):117-126. doi: 10.1513/AnnalsATS.201711-888WS.

PMID:
29388810
13.

Testing and treatment for obstructive sleep apnea in Canada: funding models must change.

Pendharkar SR, Povitz M, Bansback N, George CFP, Morrison D, Ayas NT; Canadian Sleep and Circadian Network.

CMAJ. 2017 Dec 11;189(49):E1524-E1528. doi: 10.1503/cmaj.170393. No abstract available.

14.

Diagnosis and treatment of obstructive sleep apnea in adults.

Laratta CR, Ayas NT, Povitz M, Pendharkar SR.

CMAJ. 2017 Dec 4;189(48):E1481-E1488. doi: 10.1503/cmaj.170296. Review. No abstract available.

15.

Outcomes of Critically Ill Patients Who Have Serotype 5 Invasive Pneumococcal Disease.

Zurawska JH, Romney MG, Wong H, Wang H, Ayas NT, Hoang LMN, Stefanovic A, Doyle P, Dhingra V, Dodek PM.

J Intensive Care Med. 2017 Jan 1:885066617728895. doi: 10.1177/0885066617728895. [Epub ahead of print]

PMID:
28901208
16.

Update in Sleep-disordered Breathing 2016.

Ayas NT, Drager LF, Morrell MJ, Polotsky VY.

Am J Respir Crit Care Med. 2017 Jun 15;195(12):1561-1566. doi: 10.1164/rccm.201701-0048UP. Review. No abstract available.

17.

AJRCCM: 100-Year Anniversary. Sleep-Disordered Breathing: Still the New Kid on the Block.

Ayas NT, Bhattacharjee R, Pack AI.

Am J Respir Crit Care Med. 2017 May 1;195(9):1107-1111. doi: 10.1164/rccm.201701-0199ED. No abstract available.

PMID:
28459321
18.

Cardiovascular consequences of obstructive sleep apnea.

Ayas NT, Taylor CM, Laher I.

Curr Opin Cardiol. 2016 Nov;31(6):599-605. Review.

PMID:
27652812
19.

Will This Hemodynamically Unstable Patient Respond to a Bolus of Intravenous Fluids?

Bentzer P, Griesdale DE, Boyd J, MacLean K, Sirounis D, Ayas NT.

JAMA. 2016 Sep 27;316(12):1298-309. doi: 10.1001/jama.2016.12310. Review.

PMID:
27673307
20.

Cardiovascular Events in Obstructive Sleep Apnea - Can CPAP Therapy SAVE Lives?

Mokhlesi B, Ayas NT.

N Engl J Med. 2016 Sep 8;375(10):994-6. doi: 10.1056/NEJMe1609704. Epub 2016 Aug 28. No abstract available.

PMID:
27571490
21.

Sleep Stage Coordination of Respiration and Swallowing: A Preliminary Study.

Okuno K, Nohara K, Takai E, Sakai T, Fleetham JA, Ayas NT, Lowe AA, Almeida FR.

Dysphagia. 2016 Aug;31(4):579-86. doi: 10.1007/s00455-016-9719-5. Epub 2016 Jun 23.

PMID:
27338262
22.

Cognitive and Other Strategies to Mitigate the Effects of Fatigue. Lessons from Staff Physicians Working in Intensive Care Units.

Henrich N, Ayas NT, Stelfox HT, Peets AD.

Ann Am Thorac Soc. 2016 Sep;13(9):1600-6. doi: 10.1513/AnnalsATS.201512-817OC.

PMID:
27249237
23.

Corrigendum to "length of stay and mortality due to clostridium difficile infection acquired in the intensive care unit" journal of Critical Care (2013) 28, 335-340.

Dodek PM, Norena M, Ayas NT, Romney M, Wong H.

J Crit Care. 2016 Jun;33:266. doi: 10.1016/j.jcrc.2016.03.001. Epub 2016 Mar 16. No abstract available.

PMID:
27107495
24.

Obstructive sleep apnoea and frequency of occupational injury.

Hirsch Allen AJ, Park JE, Daniele PR, Fleetham J, Ryan CF, Ayas NT.

Thorax. 2016 Jul;71(7):664-6. doi: 10.1136/thoraxjnl-2015-207994. Epub 2016 Mar 15.

PMID:
26980010
25.

Relationship between Travel Time from Home to a Regional Sleep Apnea Clinic in British Columbia, Canada, and the Severity of Obstructive Sleep.

Allen AJ, Amram O, Tavakoli H, Almeida FR, Hamoda M, Ayas NT.

Ann Am Thorac Soc. 2016 May;13(5):719-23. doi: 10.1513/AnnalsATS.201509-613BC.

PMID:
26814425
26.

Response.

Ayas NT, Allen AJMH.

Chest. 2015 Nov;148(5):e166-e167. doi: 10.1378/chest.15-1952. No abstract available.

PMID:
26527451
27.

Noninvasive ventilation practice patterns for acute respiratory failure in Canadian tertiary care centres: A descriptive analysis.

Digby GC, Keenan SP, Parker CM, Sinuff T, Burns KE, Mehta S, Ronco JJ, Kutsogiannis DJ, Rose L, Ayas NT, Berthiaume LR, D'Arsigny CL, Stollery DE, Muscedere J.

Can Respir J. 2015 Nov-Dec;22(6):331-40. Epub 2015 Oct 15.

28.

Cerebrovascular Response to CO2 Following 10 Days of Intermittent Hypoxia in Humans.

Querido JS, Welch JF, Ayas NT, Sheel AW.

Aerosp Med Hum Perform. 2015 Sep;86(9):782-6. doi: 10.3357/AMHP.4192.2015.

PMID:
26388084
29.

Gas density alters expiratory time constants before and after experimental lung injury.

Henderson WR, Molgat-Seon Y, Dominelli PB, Brasher PM, Griesdale DE, Foster GE, Yacyshyn A, Ayas NT, Sheel AW.

Exp Physiol. 2015 Oct;100(10):1217-28. doi: 10.1113/EP085205.

30.

Update in Sleep Medicine 2014.

Ayas NT, Owens RL, Kheirandish-Gozal L.

Am J Respir Crit Care Med. 2015 Aug 15;192(4):415-20. doi: 10.1164/rccm.201503-0647UP. Review. No abstract available.

PMID:
26278795
31.

Administration of intrapulmonary sodium polyacrylate to induce lung injury for the development of a porcine model of early acute respiratory distress syndrome.

Henderson WR, Barnbrook J, Dominelli PB, Griesdale DE, Arndt T, Molgat-Seon Y, Foster G, Ackland GL, Xu J, Ayas NT, Sheel AW.

Intensive Care Med Exp. 2014 Dec;2(1):5. doi: 10.1186/2197-425X-2-5. Epub 2014 Feb 26.

32.

Treatment of Central Sleep Apnea with Adaptive Servoventilation in Chronic Heart Failure.

Ayas NT, Patil SP, Stanchina M, Malhotra A.

Am J Respir Crit Care Med. 2015 Jul 15;192(2):132-3. doi: 10.1164/rccm.201506-1131ED. No abstract available.

33.

An Official American Thoracic Society Statement: The Importance of Healthy Sleep. Recommendations and Future Priorities.

Mukherjee S, Patel SR, Kales SN, Ayas NT, Strohl KP, Gozal D, Malhotra A; American Thoracic Society ad hoc Committee on Healthy Sleep.

Am J Respir Crit Care Med. 2015 Jun 15;191(12):1450-8. doi: 10.1164/rccm.201504-0767ST.

34.

The effect of OSA on work disability and work-related injuries.

Hirsch Allen AJM, Bansback N, Ayas NT.

Chest. 2015 May;147(5):1422-1428. doi: 10.1378/chest.14-1949. Review.

PMID:
25940253
35.

Obstructive Sleep Apnea and Kidney Disease: A Potential Bidirectional Relationship?

Abuyassin B, Sharma K, Ayas NT, Laher I.

J Clin Sleep Med. 2015 Aug 15;11(8):915-24. doi: 10.5664/jcsm.4946. Review.

36.

Attributable length of stay and mortality of major bleeding as a complication of therapeutic anticoagulation in the intensive care unit.

Ayas NT, Dodek PM, Wang H, Fowler R, Wong H, Norena M.

J Patient Saf. 2015 Mar;11(1):23-7. doi: 10.1097/PTS.0000000000000149.

PMID:
25517649
37.

Swallowing and breathing patterns during sleep in patients with obstructive sleep apnea.

Yagi K, Lowe AA, Ayas NT, Fleetham JA, Almeida FR.

Sleep Breath. 2015 Mar;19(1):377-84. doi: 10.1007/s11325-014-1031-8. Epub 2014 Jul 24.

PMID:
25056664
38.

New frontiers in obstructive sleep apnoea.

Ayas NT, Hirsch AA, Laher I, Bradley TD, Malhotra A, Polotsky VY, Tasali E.

Clin Sci (Lond). 2014 Aug;127(4):209-16. doi: 10.1042/CS20140070. Review.

39.

To sleep, or not to sleep, that is the question.

Ayas NT, Malhotra A, Parthsarathy S.

Crit Care Med. 2013 Jul;41(7):1808-10. doi: 10.1097/CCM.0b013e31828ce8c0. No abstract available.

40.

Dynamic cerebral autoregulation during and following acute hypoxia: role of carbon dioxide.

Querido JS, Ainslie PN, Foster GE, Henderson WR, Halliwill JR, Ayas NT, Sheel AW.

J Appl Physiol (1985). 2013 May;114(9):1183-90. doi: 10.1152/japplphysiol.00024.2013. Epub 2013 Mar 7.

41.

Length of stay and mortality due to Clostridium difficile infection acquired in the intensive care unit.

Dodek PM, Norena M, Ayas NT, Romney M, Wong H.

J Crit Care. 2013 Aug;28(4):335-40. doi: 10.1016/j.jcrc.2012.11.008. Epub 2013 Jan 18.

PMID:
23337482
42.

The relationship between organizational culture and family satisfaction in critical care.

Dodek PM, Wong H, Heyland DK, Cook DJ, Rocker GM, Kutsogiannis DJ, Dale C, Fowler R, Robinson S, Ayas NT; Canadian Researchers at the End of Life Network (CARENET).

Crit Care Med. 2012 May;40(5):1506-12. doi: 10.1097/CCM.0b013e318241e368.

PMID:
22511132
43.

The impact of a telemedicine monitoring system on positive airway pressure adherence in patients with obstructive sleep apnea: a randomized controlled trial.

Fox N, Hirsch-Allen AJ, Goodfellow E, Wenner J, Fleetham J, Ryan CF, Kwiatkowska M, Ayas NT.

Sleep. 2012 Apr 1;35(4):477-81. doi: 10.5665/sleep.1728.

44.

Does this patient with liver disease have cirrhosis?

Udell JA, Wang CS, Tinmouth J, FitzGerald JM, Ayas NT, Simel DL, Schulzer M, Mak E, Yoshida EM.

JAMA. 2012 Feb 22;307(8):832-842. doi: 10.1001/jama.2012.186.

PMID:
22357834
45.

Restricting resident work hours: the good, the bad, and the ugly.

Peets A, Ayas NT.

Crit Care Med. 2012 Mar;40(3):960-6. doi: 10.1097/CCM.0b013e3182413bc5. Review.

PMID:
22297631
46.

Organizational and safety culture in Canadian intensive care units: relationship to size of intensive care unit and physician management model.

Dodek PM, Wong H, Jaswal D, Heyland DK, Cook DJ, Rocker GM, Kutsogiannis DJ, Dale C, Fowler R, Ayas NT.

J Crit Care. 2012 Feb;27(1):11-7. doi: 10.1016/j.jcrc.2011.07.078. Epub 2011 Sep 29.

PMID:
21958984
47.

Effects of 10 days of modest intermittent hypoxia on circulating measures of inflammation in healthy humans.

Querido JS, Sheel AW, Cheema R, Van Eeden S, Mulgrew AT, Ayas NT.

Sleep Breath. 2012 Sep;16(3):657-62. doi: 10.1007/s11325-011-0555-4. Epub 2011 Jul 9.

PMID:
21743982
48.

The demise of portable monitoring to diagnose OSA? Not so fast!

Ayas NT, Pack A, Marra C.

Sleep. 2011 Jun 1;34(6):691-2. doi: 10.5665/SLEEP.1026. No abstract available.

49.

The relationship between mouth opening and sleep stage-related sleep disordered breathing.

Tsuda H, Lowe AA, Chen H, Fleetham JA, Ayas NT, Almeida FR.

J Clin Sleep Med. 2011 Apr 15;7(2):181-6.

50.

Medical simulation in respiratory and critical care medicine.

Lam G, Ayas NT, Griesdale DE, Peets AD.

Lung. 2010 Dec;188(6):445-57. doi: 10.1007/s00408-010-9260-5. Epub 2010 Sep 24. Review.

PMID:
20865270

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