Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 57


Double sequential defibrillation for out-of-hospital refractory ventricular fibrillation: A scoping review.

Miraglia D, Miguel LA, Alonso W, Ayala JE.

Am J Emerg Med. 2019 Dec 24. pii: S0735-6757(19)30851-4. doi: 10.1016/j.ajem.2019.12.047. [Epub ahead of print] Review.


Mannose Alters Gut Microbiome, Prevents Diet-Induced Obesity, and Improves Host Metabolism.

Sharma V, Smolin J, Nayak J, Ayala JE, Scott DA, Peterson SN, Freeze HH.

Cell Rep. 2018 Sep 18;24(12):3087-3098. doi: 10.1016/j.celrep.2018.08.064.


Oleoylethanolamide modulates glucagon-like peptide-1 receptor agonist signaling and enhances exendin-4-mediated weight loss in obese mice.

Brown JD, McAnally D, Ayala JE, Burmeister MA, Morfa C, Smith L, Ayala JE.

Am J Physiol Regul Integr Comp Physiol. 2018 Oct 1;315(4):R595-R608. doi: 10.1152/ajpregu.00459.2017. Epub 2018 Jun 27.


Elevated Nicotinamide Phosphoribosyl Transferase in Skeletal Muscle Augments Exercise Performance and Mitochondrial Respiratory Capacity Following Exercise Training.

Brouwers B, Stephens NA, Costford SR, Hopf ME, Ayala JE, Yi F, Xie H, Li JL, Gardell SJ, Sparks LM, Smith SR.

Front Physiol. 2018 Jun 11;9:704. doi: 10.3389/fphys.2018.00704. eCollection 2018.


Impaired Mitochondrial Energetics Characterize Poor Early Recovery of Muscle Mass Following Hind Limb Unloading in Old Mice.

Zhang X, Trevino MB, Wang M, Gardell SJ, Ayala JE, Han X, Kelly DP, Goodpaster BH, Vega RB, Coen PM.

J Gerontol A Biol Sci Med Sci. 2018 Sep 11;73(10):1313-1322. doi: 10.1093/gerona/gly051.


Membrane Trafficking Protein CDP138 Regulates Fat Browning and Insulin Sensitivity through Controlling Catecholamine Release.

Zhou QL, Song Y, Huang CH, Huang JY, Gong Z, Liao Z, Sharma AG, Greene L, Deng JZ, Rigor MC, Xie X, Qi S, Ayala JE, Jiang ZY.

Mol Cell Biol. 2018 Mar 29;38(8). pii: e00153-17. doi: 10.1128/MCB.00153-17. Print 2018 Apr 15.


Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance.

Costford SR, Brouwers B, Hopf ME, Sparks LM, Dispagna M, Gomes AP, Cornnell HH, Petucci C, Phelan P, Xie H, Yi F, Walter GA, Osborne TF, Sinclair DA, Mynatt RL, Ayala JE, Gardell SJ, Smith SR.

Mol Metab. 2018 Jan;7:1-11. doi: 10.1016/j.molmet.2017.10.012. Epub 2017 Nov 6.


The glucagon-like peptide-1 receptor in the ventromedial hypothalamus reduces short-term food intake in male mice by regulating nutrient sensor activity.

Burmeister MA, Brown JD, Ayala JE, Stoffers DA, Sandoval DA, Seeley RJ, Ayala JE.

Am J Physiol Endocrinol Metab. 2017 Dec 1;313(6):E651-E662. doi: 10.1152/ajpendo.00113.2017. Epub 2017 Aug 15.


Oleoylethanolamide: A fat ally in the fight against obesity.

Brown JD, Karimian Azari E, Ayala JE.

Physiol Behav. 2017 Jul 1;176:50-58. doi: 10.1016/j.physbeh.2017.02.034. Epub 2017 Feb 27. Review.


The Hypothalamic Glucagon-Like Peptide 1 Receptor Is Sufficient but Not Necessary for the Regulation of Energy Balance and Glucose Homeostasis in Mice.

Burmeister MA, Ayala JE, Smouse H, Landivar-Rocha A, Brown JD, Drucker DJ, Stoffers DA, Sandoval DA, Seeley RJ, Ayala JE.

Diabetes. 2017 Feb;66(2):372-384. doi: 10.2337/db16-1102. Epub 2016 Dec 1.


Cellular Sites and Mechanisms Linking Reduction of Dipeptidyl Peptidase-4 Activity to Control of Incretin Hormone Action and Glucose Homeostasis.

Mulvihill EE, Varin EM, Gladanac B, Campbell JE, Ussher JR, Baggio LL, Yusta B, Ayala J, Burmeister MA, Matthews D, Bang KWA, Ayala JE, Drucker DJ.

Cell Metab. 2017 Jan 10;25(1):152-165. doi: 10.1016/j.cmet.2016.10.007. Epub 2016 Nov 10.


Disruption of the sugar-sensing receptor T1R2 attenuates metabolic derangements associated with diet-induced obesity.

Smith KR, Hussain T, Karimian Azari E, Steiner JL, Ayala JE, Pratley RE, Kyriazis GA.

Am J Physiol Endocrinol Metab. 2016 Apr 15;310(8):E688-E698. doi: 10.1152/ajpendo.00484.2015. Epub 2016 Feb 16.


Leptin recruits Creb-regulated transcriptional coactivator 1 to improve hyperglycemia in insulin-deficient diabetes.

Kim GH, Szabo A, King EM, Ayala J, Ayala JE, Altarejos JY.

Mol Metab. 2014 Dec 19;4(3):227-36. doi: 10.1016/j.molmet.2014.12.006. eCollection 2015 Mar.


Exendin-4 improves cardiac function in mice overexpressing monocyte chemoattractant protein-1 in cardiomyocytes.

Younce CW, Niu J, Ayala J, Burmeister MA, Smith LH, Kolattukudy P, Ayala JE.

J Mol Cell Cardiol. 2014 Nov;76:172-6. doi: 10.1016/j.yjmcc.2014.08.022. Epub 2014 Sep 6.


Insulin sensitivity in long-living Ames dwarf mice.

Wiesenborn DS, Ayala JE, King E, Masternak MM.

Age (Dordr). 2014;36(5):9709. doi: 10.1007/s11357-014-9709-1. Epub 2014 Aug 29.


Striatal dopamine homeostasis is altered in mice following Roux-en-Y gastric bypass surgery.

Reddy IA, Wasserman DH, Ayala JE, Hasty AH, Abumrad NN, Galli A.

ACS Chem Neurosci. 2014 Oct 15;5(10):943-51. doi: 10.1021/cn500137d. Epub 2014 Aug 5.


Central glucagon-like peptide 1 receptor-induced anorexia requires glucose metabolism-mediated suppression of AMPK and is impaired by central fructose.

Burmeister MA, Ayala J, Drucker DJ, Ayala JE.

Am J Physiol Endocrinol Metab. 2013 Apr 1;304(7):E677-85. doi: 10.1152/ajpendo.00446.2012. Epub 2013 Jan 22.


Exendin-4 attenuates high glucose-induced cardiomyocyte apoptosis via inhibition of endoplasmic reticulum stress and activation of SERCA2a.

Younce CW, Burmeister MA, Ayala JE.

Am J Physiol Cell Physiol. 2013 Mar;304(6):C508-18. doi: 10.1152/ajpcell.00248.2012. Epub 2013 Jan 9.


Regulation of endogenous glucose production in glucose transporter 4 over-expressing mice.

Berglund ED, Li CY, Ayala JE, McGuinness OP, Wasserman DH.

PLoS One. 2012;7(12):e52355. doi: 10.1371/journal.pone.0052355. Epub 2012 Dec 17.


Regulation of glucose kinetics during exercise by the glucagon-like peptide-1 receptor.

Burmeister MA, Bracy DP, James FD, Holt RM, Ayala J, King EM, Wasserman DH, Drucker DJ, Ayala JE.

J Physiol. 2012 Oct 15;590(20):5245-55. doi: 10.1113/jphysiol.2012.234914. Epub 2012 Aug 13.


Tissue engineering the monosynaptic circuit of the stretch reflex arc with co-culture of embryonic motoneurons and proprioceptive sensory neurons.

Guo X, Ayala JE, Gonzalez M, Stancescu M, Lambert S, Hickman JJ.

Biomaterials. 2012 Aug;33(23):5723-31. doi: 10.1016/j.biomaterials.2012.04.042. Epub 2012 May 15.


The nuclear receptor PPARβ/δ programs muscle glucose metabolism in cooperation with AMPK and MEF2.

Gan Z, Burkart-Hartman EM, Han DH, Finck B, Leone TC, Smith EY, Ayala JE, Holloszy J, Kelly DP.

Genes Dev. 2011 Dec 15;25(24):2619-30. doi: 10.1101/gad.178434.111. Epub 2011 Dec 1.


Hyperinsulinemic-euglycemic clamps in conscious, unrestrained mice.

Ayala JE, Bracy DP, Malabanan C, James FD, Ansari T, Fueger PT, McGuinness OP, Wasserman DH.

J Vis Exp. 2011 Nov 16;(57). pii: 3188. doi: 10.3791/3188.


Acute activation of central GLP-1 receptors enhances hepatic insulin action and insulin secretion in high-fat-fed, insulin resistant mice.

Burmeister MA, Ferre T, Ayala JE, King EM, Holt RM, Ayala JE.

Am J Physiol Endocrinol Metab. 2012 Feb 1;302(3):E334-43. doi: 10.1152/ajpendo.00409.2011. Epub 2011 Nov 15.


Diet-induced muscle insulin resistance is associated with extracellular matrix remodeling and interaction with integrin alpha2beta1 in mice.

Kang L, Ayala JE, Lee-Young RS, Zhang Z, James FD, Neufer PD, Pozzi A, Zutter MM, Wasserman DH.

Diabetes. 2011 Feb;60(2):416-26. doi: 10.2337/db10-1116.


The physiological regulation of glucose flux into muscle in vivo.

Wasserman DH, Kang L, Ayala JE, Fueger PT, Lee-Young RS.

J Exp Biol. 2011 Jan 15;214(Pt 2):254-62. doi: 10.1242/jeb.048041.


Obesity impairs skeletal muscle AMPK signaling during exercise: role of AMPKα2 in the regulation of exercise capacity in vivo.

Lee-Young RS, Ayala JE, Fueger PT, Mayes WH, Kang L, Wasserman DH.

Int J Obes (Lond). 2011 Jul;35(7):982-9. doi: 10.1038/ijo.2010.220. Epub 2010 Nov 16.


Measuring salivary analytes from free-ranging monkeys.

Higham JP, Vitale AB, Rivera AM, Ayala JE, Maestripieri D.

Physiol Behav. 2010 Dec 2;101(5):601-7. doi: 10.1016/j.physbeh.2010.09.003. Epub 2010 Sep 15.


Terminal investment and senescence in rhesus macaques (Macaca mulatta) on Cayo Santiago.

Hoffman CL, Higham JP, Mas-Rivera A, Ayala JE, Maestripieri D.

Behav Ecol. 2010 Sep;21(5):972-978. Epub 2010 Jun 29.


Standard operating procedures for describing and performing metabolic tests of glucose homeostasis in mice.

Ayala JE, Samuel VT, Morton GJ, Obici S, Croniger CM, Shulman GI, Wasserman DH, McGuinness OP; NIH Mouse Metabolic Phenotyping Center Consortium.

Dis Model Mech. 2010 Sep-Oct;3(9-10):525-34. doi: 10.1242/dmm.006239. Epub 2010 Aug 16.


Glucagon-like peptide-1 receptor knockout mice are protected from high-fat diet-induced insulin resistance.

Ayala JE, Bracy DP, James FD, Burmeister MA, Wasserman DH, Drucker DJ.

Endocrinology. 2010 Oct;151(10):4678-87. doi: 10.1210/en.2010-0289. Epub 2010 Aug 4.


Endothelial nitric oxide synthase is central to skeletal muscle metabolic regulation and enzymatic signaling during exercise in vivo.

Lee-Young RS, Ayala JE, Hunley CF, James FD, Bracy DP, Kang L, Wasserman DH.

Am J Physiol Regul Integr Comp Physiol. 2010 May;298(5):R1399-408. doi: 10.1152/ajpregu.00004.2010. Epub 2010 Mar 3.


Effects of reproductive condition and dominance rank on cortisol responsiveness to stress in free-ranging female rhesus macaques.

Hoffman CL, Ayala JE, Mas-Rivera A, Maestripieri D.

Am J Primatol. 2010 Jun;72(7):559-65. doi: 10.1002/ajp.20793.


Context-dependent pharmacology exhibited by negative allosteric modulators of metabotropic glutamate receptor 7.

Niswender CM, Johnson KA, Miller NR, Ayala JE, Luo Q, Williams R, Saleh S, Orton D, Weaver CD, Conn PJ.

Mol Pharmacol. 2010 Mar;77(3):459-68. doi: 10.1124/mol.109.058768. Epub 2009 Dec 21.


Lost in translation.

Wasserman DH, Ayala JE, McGuinness OP.

Diabetes. 2009 Sep;58(9):1947-50. doi: 10.2337/db09-0537. No abstract available.


NIH experiment in centralized mouse phenotyping: the Vanderbilt experience and recommendations for evaluating glucose homeostasis in the mouse.

McGuinness OP, Ayala JE, Laughlin MR, Wasserman DH.

Am J Physiol Endocrinol Metab. 2009 Oct;297(4):E849-55. doi: 10.1152/ajpendo.90996.2008. Epub 2009 Jul 28. Review.


Skeletal muscle AMP-activated protein kinase is essential for the metabolic response to exercise in vivo.

Lee-Young RS, Griffee SR, Lynes SE, Bracy DP, Ayala JE, McGuinness OP, Wasserman DH.

J Biol Chem. 2009 Sep 4;284(36):23925-34. doi: 10.1074/jbc.M109.021048. Epub 2009 Jun 12.


mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning.

Ayala JE, Chen Y, Banko JL, Sheffler DJ, Williams R, Telk AN, Watson NL, Xiang Z, Zhang Y, Jones PJ, Lindsley CW, Olive MF, Conn PJ.

Neuropsychopharmacology. 2009 Aug;34(9):2057-71. doi: 10.1038/npp.2009.30. Epub 2009 Mar 18.


The glucagon-like peptide-1 receptor regulates endogenous glucose production and muscle glucose uptake independent of its incretin action.

Ayala JE, Bracy DP, James FD, Julien BM, Wasserman DH, Drucker DJ.

Endocrinology. 2009 Mar;150(3):1155-64. doi: 10.1210/en.2008-0945. Epub 2008 Nov 13.


Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4.

Niswender CM, Johnson KA, Weaver CD, Jones CK, Xiang Z, Luo Q, Rodriguez AL, Marlo JE, de Paulis T, Thompson AD, Days EL, Nalywajko T, Austin CA, Williams MB, Ayala JE, Williams R, Lindsley CW, Conn PJ.

Mol Pharmacol. 2008 Nov;74(5):1345-58. doi: 10.1124/mol.108.049551. Epub 2008 Jul 29.


Glucose metabolism in vivo in four commonly used inbred mouse strains.

Berglund ED, Li CY, Poffenberger G, Ayala JE, Fueger PT, Willis SE, Jewell MM, Powers AC, Wasserman DH.

Diabetes. 2008 Jul;57(7):1790-9. doi: 10.2337/db07-1615. Epub 2008 Apr 8.


Group III mGluR regulation of synaptic transmission at the SC-CA1 synapse is developmentally regulated.

Ayala JE, Niswender CM, Luo Q, Banko JL, Conn PJ.

Neuropharmacology. 2008 Apr;54(5):804-14. doi: 10.1016/j.neuropharm.2007.12.009. Epub 2007 Dec 24.


A novel assay of Gi/o-linked G protein-coupled receptor coupling to potassium channels provides new insights into the pharmacology of the group III metabotropic glutamate receptors.

Niswender CM, Johnson KA, Luo Q, Ayala JE, Kim C, Conn PJ, Weaver CD.

Mol Pharmacol. 2008 Apr;73(4):1213-24. doi: 10.1124/mol.107.041053. Epub 2008 Jan 2.


An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission.

Shirey JK, Xiang Z, Orton D, Brady AE, Johnson KA, Williams R, Ayala JE, Rodriguez AL, Wess J, Weaver D, Niswender CM, Conn PJ.

Nat Chem Biol. 2008 Jan;4(1):42-50. Epub 2007 Dec 2.


Insulin action in the double incretin receptor knockout mouse.

Ayala JE, Bracy DP, Hansotia T, Flock G, Seino Y, Wasserman DH, Drucker DJ.

Diabetes. 2008 Feb;57(2):288-97. Epub 2007 Oct 31.


Glucose kinetics and exercise tolerance in mice lacking the GLUT4 glucose transporter.

Fueger PT, Li CY, Ayala JE, Shearer J, Bracy DP, Charron MJ, Rottman JN, Wasserman DH.

J Physiol. 2007 Jul 15;582(Pt 2):801-12. Epub 2007 May 10.


Chronic treatment with sildenafil improves energy balance and insulin action in high fat-fed conscious mice.

Ayala JE, Bracy DP, Julien BM, Rottman JN, Fueger PT, Wasserman DH.

Diabetes. 2007 Apr;56(4):1025-33. Epub 2007 Jan 17.


Considerations in the design of hyperinsulinemic-euglycemic clamps in the conscious mouse.

Ayala JE, Bracy DP, McGuinness OP, Wasserman DH.

Diabetes. 2006 Feb;55(2):390-7.


Interaction of physiological mechanisms in control of muscle glucose uptake.

Wasserman DH, Ayala JE.

Clin Exp Pharmacol Physiol. 2005 Apr;32(4):319-23. Review.


Insulin-mediated activation of activator protein-1 through the mitogen-activated protein kinase pathway stimulates collagenase-1 gene transcription in the MES 13 mesangial cell line.

Ayala JE, Boustead JN, Chapman SC, Svitek CA, Oeser JK, Robey RB, O'Brien RM.

J Mol Endocrinol. 2004 Aug;33(1):263-80.


Supplemental Content

Loading ...
Support Center