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Items: 49

1.

Myositis with sarcoplasmic inclusions in Nakajo-Nishimura syndrome: a genetic inflammatory myopathy.

Ayaki T, Murata K, Kanazawa N, Uruha A, Ohmura K, Sugie K, Kasagi S, Li F, Mori M, Nakajima R, Sasai T, Nishino I, Satoshi U, Makoto U, Fukumi F, Ito H, Takahashi R.

Neuropathol Appl Neurobiol. 2020 Mar 6. doi: 10.1111/nan.12614. [Epub ahead of print]

PMID:
32144790
2.

Linear Polyubiquitin Chain Modification of TDP-43-Positive Neuronal Cytoplasmic Inclusions in Amyotrophic Lateral Sclerosis.

Nakayama Y, Tsuji K, Ayaki T, Mori M, Tokunaga F, Ito H.

J Neuropathol Exp Neurol. 2020 Mar 1;79(3):256-265. doi: 10.1093/jnen/nlz135.

PMID:
31951008
3.

α-Synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: a prodromal Parkinson's disease model.

Taguchi T, Ikuno M, Hondo M, Parajuli LK, Taguchi K, Ueda J, Sawamura M, Okuda S, Nakanishi E, Hara J, Uemura N, Hatanaka Y, Ayaki T, Matsuzawa S, Tanaka M, El-Agnaf OMA, Koike M, Yanagisawa M, Uemura MT, Yamakado H, Takahashi R.

Brain. 2020 Jan 1;143(1):249-265. doi: 10.1093/brain/awz380.

PMID:
31816026
4.

Induced pluripotent stem cell-based Drug Repurposing for Amyotrophic lateral sclerosis Medicine (iDReAM) study: protocol for a phase I dose escalation study of bosutinib for amyotrophic lateral sclerosis patients.

Imamura K, Izumi Y, Banno H, Uozumi R, Morita S, Egawa N, Ayaki T, Nagai M, Nishiyama K, Watanabe Y, Hanajima R, Oki R, Fujita K, Takahashi N, Ikeda T, Shimizu A, Morinaga A, Hirohashi T, Fujii Y, Takahashi R, Inoue H.

BMJ Open. 2019 Dec 2;9(12):e033131. doi: 10.1136/bmjopen-2019-033131.

5.

Two cases of delayed perforating artery infarction adjacent to intracranial hemorrhage.

Yasuda K, Maki T, Kimura K, Ayaki T, Sawamoto N, Murase N, Ohtani R, Takahashi R, Nakamura M.

eNeurologicalSci. 2019 Sep 12;17:100209. doi: 10.1016/j.ensci.2019.100209. eCollection 2019 Dec. No abstract available.

6.

Role of Perivascular Oligodendrocyte Precursor Cells in Angiogenesis After Brain Ischemia.

Kishida N, Maki T, Takagi Y, Yasuda K, Kinoshita H, Ayaki T, Noro T, Kinoshita Y, Ono Y, Kataoka H, Yoshida K, Lo EH, Arai K, Miyamoto S, Takahashi R.

J Am Heart Assoc. 2019 May 7;8(9):e011824. doi: 10.1161/JAHA.118.011824.

7.

Chronic cerebral hypoperfusion upregulates leptin receptor expression in astrocytes and tau phosphorylation in tau transgenic mice.

Shimada T, Shindo A, Matsuyama H, Yata K, Niwa A, Sasaki R, Ayaki T, Maki T, Wakita H, Tomimoto H.

Neurosci Lett. 2019 Jun 21;704:133-140. doi: 10.1016/j.neulet.2019.04.009. Epub 2019 Apr 4.

PMID:
30954605
8.

Phosphorylated NF-κB subunit p65 aggregates in granulovacuolar degeneration and neurites in neurodegenerative diseases with tauopathy.

Yamaguchi Y, Ayaki T, Li F, Tsujimura A, Kamada M, Ito H, Maki T, Sawamoto N, Urushitani M, Takahashi R.

Neurosci Lett. 2019 Jun 21;704:229-235. doi: 10.1016/j.neulet.2019.03.036. Epub 2019 Apr 1.

PMID:
30946927
9.

[An autopsy case after endovascular thrombectomy for cardioembolic stroke due to nonbacterial thrombotic endocarditis].

Yasuda K, Ayaki T, Kawabata Y, Murase N, Ohtani R, Nakamura M.

Rinsho Shinkeigaku. 2019 Apr 25;59(4):195-199. doi: 10.5692/clinicalneurol.cn-001252. Epub 2019 Mar 30. Japanese.

PMID:
30930366
10.

Identification of linear polyubiquitin chain immunoreactivity in tau pathology of Alzheimer's disease.

Nakayama Y, Sakamoto S, Tsuji K, Ayaki T, Tokunaga F, Ito H.

Neurosci Lett. 2019 Jun 11;703:53-57. doi: 10.1016/j.neulet.2019.03.017. Epub 2019 Mar 15.

PMID:
30885635
11.

Recurrent Epstein-Barr Virus-positive (EBV+) Primary Central Nervous System Lymphoma (PCNSL) in a Patient with Clinical Features of Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS).

Nagano M, Ayaki T, Koita N, Kitano T, Nishikori M, Goda N, Minamiguchi S, Ikeda A, Takaori-Kondo A, Takahashi R.

Intern Med. 2019;58(6):849-854. doi: 10.2169/internalmedicine.1246-18. Epub 2019 Mar 15.

12.

Utility of osteopontin in cerebrospinal fluid as a diagnostic marker for neuropsychiatric systemic lupus erythematosus.

Kitagori K, Yoshifuji H, Oku T, Ayaki T, Kuzuya A, Nakajima T, Akizuki S, Nakashima R, Murakami K, Ohmura K, Hirayama Y, Takahashi R, Mimori T.

Lupus. 2019 Mar;28(3):414-422. doi: 10.1177/0961203319828818. Epub 2019 Feb 11.

PMID:
30744522
13.

Non-aneurysmal Subarachnoid Hemorrhaging: A Rare Cause of Death in a Patient with Multiple System Atrophy.

Kinoshita H, Ayaki T, Maki T, Goda N, Yoshizawa A, Takahashi R.

Intern Med. 2019 Jun 1;58(11):1643-1644. doi: 10.2169/internalmedicine.1567-18. Epub 2019 Feb 1.

14.

NLRP3 Inflammasome-Related Proteins Are Upregulated in the Putamen of Patients With Multiple System Atrophy.

Li F, Ayaki T, Maki T, Sawamoto N, Takahashi R.

J Neuropathol Exp Neurol. 2018 Nov 1;77(11):1055-1065. doi: 10.1093/jnen/nly090.

PMID:
30295793
15.
16.

Elimination of TDP-43 inclusions linked to amyotrophic lateral sclerosis by a misfolding-specific intrabody with dual proteolytic signals.

Tamaki Y, Shodai A, Morimura T, Hikiami R, Minamiyama S, Ayaki T, Tooyama I, Furukawa Y, Takahashi R, Urushitani M.

Sci Rep. 2018 Apr 16;8(1):6030. doi: 10.1038/s41598-018-24463-3.

17.

Amyotrophic Lateral Sclerosis after Receiving the Human Papilloma Virus Vaccine: A Case Report of a 15-year-old Girl.

Hikiami R, Yamakado H, Tatsumi S, Ayaki T, Hashi Y, Yamashita H, Sawamoto N, Tsuji T, Urushitani M, Takahashi R.

Intern Med. 2018 Jul 1;57(13):1917-1919. doi: 10.2169/internalmedicine.0285-17. Epub 2018 Feb 9.

18.

Complement Activation in Capillary Cerebral Amyloid Angiopathy.

Matsuo K, Shindo A, Niwa A, Tabei KI, Akatsu H, Hashizume Y, Akiyama H, Ayaki T, Maki T, Sawamoto N, Takahashi R, Oikawa S, Tomimoto H.

Dement Geriatr Cogn Disord. 2017;44(5-6):343-353. doi: 10.1159/000486091. Epub 2018 Feb 8.

PMID:
29421784
19.

Pathological Endogenous α-Synuclein Accumulation in Oligodendrocyte Precursor Cells Potentially Induces Inclusions in Multiple System Atrophy.

Kaji S, Maki T, Kinoshita H, Uemura N, Ayaki T, Kawamoto Y, Furuta T, Urushitani M, Hasegawa M, Kinoshita Y, Ono Y, Mao X, Quach TH, Iwai K, Dawson VL, Dawson TM, Takahashi R.

Stem Cell Reports. 2018 Feb 13;10(2):356-365. doi: 10.1016/j.stemcr.2017.12.001. Epub 2018 Jan 11.

20.

Multiple Proteinopathies in Familial ALS Cases With Optineurin Mutations.

Ayaki T, Ito H, Komure O, Kamada M, Nakamura M, Wate R, Kusaka H, Yamaguchi Y, Li F, Kawakami H, Urushitani M, Takahashi R.

J Neuropathol Exp Neurol. 2018 Feb 1;77(2):128-138. doi: 10.1093/jnen/nlx109.

PMID:
29272468
21.

FKBP12-immunopositive inclusions in patients with α-synucleinopathies.

Honjo Y, Ayaki T, Horibe T, Ito H, Takahashi R, Kawakami K.

Brain Res. 2018 Feb 1;1680:39-45. doi: 10.1016/j.brainres.2017.12.012. Epub 2017 Dec 12.

PMID:
29246765
22.

Decreased levels of PDI and P5 in oligodendrocytes in Alzheimer's disease.

Honjo Y, Ayaki T, Tomiyama T, Horibe T, Ito H, Mori H, Takahashi R, Kawakami K.

Neuropathology. 2017 Dec;37(6):495-501. doi: 10.1111/neup.12395. Epub 2017 Jul 21.

PMID:
28731225
23.

The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.

Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, Kunath T, Wray S, Furuya H, Era T, Makioka K, Okamoto K, Fujisawa T, Nishitoh H, Homma K, Ichijo H, Julien JP, Obata N, Hosokawa M, Akiyama H, Kaneko S, Ayaki T, Ito H, Kaji R, Takahashi R, Yamanaka S, Inoue H.

Sci Transl Med. 2017 May 24;9(391). pii: eaaf3962. doi: 10.1126/scitranslmed.aaf3962.

24.

Erratum to: Modeling Alexander disease with patient iPSCs reveals cellular and molecular pathology of astrocytes.

Kondo T, Funayama M, Miyake M, Tsukita K, Era T, Osaka H, Ayaki T, Takahashi R, Inoue H.

Acta Neuropathol Commun. 2016 Sep 16;4(1):101. No abstract available.

25.

Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.

Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, Ishitani R, Kamei K, Takeyoshi I, Kawakami H, Iwai K, Hatada I, Sawasaki T, Ito H, Nureki O, Tokunaga F.

Nat Commun. 2016 Aug 24;7:12547. doi: 10.1038/ncomms12547.

26.

Modeling Alexander disease with patient iPSCs reveals cellular and molecular pathology of astrocytes.

Kondo T, Funayama M, Miyake M, Tsukita K, Era T, Osaka H, Ayaki T, Takahashi R, Inoue H.

Acta Neuropathol Commun. 2016 Jul 11;4(1):69. doi: 10.1186/s40478-016-0337-0. Erratum in: Acta Neuropathol Commun. 2016;4(1):101.

27.

Activated caspase-9 immunoreactivity in glial and neuronal cytoplasmic inclusions in multiple system atrophy.

Kawamoto Y, Ayaki T, Urushitani M, Ito H, Takahashi R.

Neurosci Lett. 2016 Aug 15;628:207-12. doi: 10.1016/j.neulet.2016.06.036. Epub 2016 Jun 21.

PMID:
27345387
28.

CUL2-mediated clearance of misfolded TDP-43 is paradoxically affected by VHL in oligodendrocytes in ALS.

Uchida T, Tamaki Y, Ayaki T, Shodai A, Kaji S, Morimura T, Banno Y, Nishitsuji K, Sakashita N, Maki T, Yamashita H, Ito H, Takahashi R, Urushitani M.

Sci Rep. 2016 Jan 11;6:19118. doi: 10.1038/srep19118.

29.

Gradual cerebral hypoperfusion in spontaneously hypertensive rats induces slowly evolving white matter abnormalities and impairs working memory.

Kitamura A, Saito S, Maki T, Oishi N, Ayaki T, Hattori Y, Yamamoto Y, Urushitani M, Kalaria RN, Fukuyama H, Horsburgh K, Takahashi R, Ihara M.

J Cereb Blood Flow Metab. 2016 Sep;36(9):1592-602. doi: 10.1177/0271678X15606717. Epub 2015 Oct 13.

30.

Increased GADD34 in oligodendrocytes in Alzheimer's disease.

Honjo Y, Ayaki T, Tomiyama T, Horibe T, Ito H, Mori H, Takahashi R, Kawakami K.

Neurosci Lett. 2015 Aug 18;602:50-5. doi: 10.1016/j.neulet.2015.06.052. Epub 2015 Jul 2.

PMID:
26142647
31.

Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant.

Ayaki T, Ito H, Fukushima H, Inoue T, Kondo T, Ikemoto A, Asano T, Shodai A, Fujita T, Fukui S, Morino H, Nakano S, Kusaka H, Yamashita H, Ihara M, Matsumoto R, Kawamata J, Urushitani M, Kawakami H, Takahashi R.

Acta Neuropathol Commun. 2014 Dec 10;2:172. doi: 10.1186/s40478-014-0172-0.

32.

Immunohistochemical localization of apoptosome-related proteins in Lewy bodies in Parkinson's disease and dementia with Lewy bodies.

Kawamoto Y, Ito H, Ayaki T, Takahashi R.

Brain Res. 2014 Jul 7;1571:39-48. doi: 10.1016/j.brainres.2014.05.007. Epub 2014 May 13.

PMID:
24835407
33.

Transglutaminase 2 accelerates neuroinflammation in amyotrophic lateral sclerosis through interaction with misfolded superoxide dismutase 1.

Oono M, Okado-Matsumoto A, Shodai A, Ido A, Ohta Y, Abe K, Ayaki T, Ito H, Takahashi R, Taniguchi N, Urushitani M.

J Neurochem. 2014 Feb;128(3):403-18. doi: 10.1111/jnc.12441. Epub 2013 Sep 30.

34.

Clinicopathologic features of autosomal recessive amyotrophic lateral sclerosis associated with optineurin mutation.

Kamada M, Izumi Y, Ayaki T, Nakamura M, Kagawa S, Kudo E, Sako W, Maruyama H, Nishida Y, Kawakami H, Ito H, Kaji R.

Neuropathology. 2014 Feb;34(1):64-70. doi: 10.1111/neup.12051. Epub 2013 Jul 29.

PMID:
23889540
35.

Response to comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells".

Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H.

Sci Transl Med. 2013 Jun 5;5(188):188lr2. doi: 10.1126/scitranslmed.3005697.

36.

Aberrant assembly of RNA recognition motif 1 links to pathogenic conversion of TAR DNA-binding protein of 43 kDa (TDP-43).

Shodai A, Morimura T, Ido A, Uchida T, Ayaki T, Takahashi R, Kitazawa S, Suzuki S, Shirouzu M, Kigawa T, Muto Y, Yokoyama S, Takahashi R, Kitahara R, Ito H, Fujiwara N, Urushitani M.

J Biol Chem. 2013 May 24;288(21):14886-905. doi: 10.1074/jbc.M113.451849. Epub 2013 Apr 4.

37.

Conserved acidic amino acid residues in a second RNA recognition motif regulate assembly and function of TDP-43.

Shodai A, Ido A, Fujiwara N, Ayaki T, Morimura T, Oono M, Uchida T, Takahashi R, Ito H, Urushitani M.

PLoS One. 2012;7(12):e52776. doi: 10.1371/journal.pone.0052776. Epub 2012 Dec 26.

38.

[Patient of myofibrillar myopathy associated with muscle cramp and distal muscle involvement].

Okada Y, Ayaki T, Matsumoto R, Ito H, Takahashi R, Nakano S.

Rinsho Shinkeigaku. 2012;52(10):774-7. Japanese.

PMID:
23064629
39.

Drug screening for ALS using patient-specific induced pluripotent stem cells.

Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H.

Sci Transl Med. 2012 Aug 1;4(145):145ra104. doi: 10.1126/scitranslmed.3004052.

40.

Clinicopathologic study on an ALS family with a heterozygous E478G optineurin mutation.

Ito H, Nakamura M, Komure O, Ayaki T, Wate R, Maruyama H, Nakamura Y, Fujita K, Kaneko S, Okamoto Y, Ihara M, Konishi T, Ogasawara K, Hirano A, Kusaka H, Kaji R, Takahashi R, Kawakami H.

Acta Neuropathol. 2011 Aug;122(2):223-9. doi: 10.1007/s00401-011-0842-y. Epub 2011 Jun 5.

PMID:
21644038
41.

A case of sporadic adult Alexander disease presenting with acute onset, remission and relapse.

Ayaki T, Shinohara M, Tatsumi S, Namekawa M, Yamamoto T.

J Neurol Neurosurg Psychiatry. 2010 Nov;81(11):1292-3. doi: 10.1136/jnnp.2009.178079. Epub 2010 Jun 18. No abstract available.

PMID:
20562394
42.

Type of gradient recalled-echo sequence results in size and number change of cerebral microbleeds.

Tatsumi S, Ayaki T, Shinohara M, Yamamoto T.

AJNR Am J Neuroradiol. 2008 Apr;29(4):e13. doi: 10.3174/ajnr.A0908. Epub 2008 Jan 9. No abstract available.

43.

Sexual Disruption in the Freshwater Crab (Geothelphusa dehaani).

Ayaki T, Kawauchino Y, Nishimura C, Ishibashi H, Arizono K.

Integr Comp Biol. 2005 Jan;45(1):39-42. doi: 10.1093/icb/45.1.39.

PMID:
21676743
44.

Mutations induced in Drosophila during space flight.

Ikenaga M, Yoshikawa I, Kojo M, Ayaki T, Ryo H, Ishizaki K, Kato T, Yamamoto H, Hara R.

Biol Sci Space. 1997 Dec;11(4):346-50.

46.

Proliferation of both somatic and germ cells is affected in the Drosophila mutants of raf proto-oncogene.

Nishida Y, Hata M, Ayaki T, Ryo H, Yamagata M, Shimizu K, Nishizuka Y.

EMBO J. 1988 Mar;7(3):775-81.

47.
49.

The relationship between lethal mutation yield and intake of ethylnitrosourea (ENU) in Drosophila melanogaster.

Ayaki T, Ohshima K, Okumura Y, Yoshikawa I, Shiomi T.

Environ Mutagen. 1984;6(4):483-8.

PMID:
6432523

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