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Olecranon fractures in children and adolescents: outcomes based on fracture fixation.

Perkins CA, Busch MT, Christino MA, Axelrod J, Devito DP, Fabregas JA, Flanagan JC, Murphy J, Olszewski D, Schmitz ML, Schrader T, Willimon SC.

J Child Orthop. 2018 Oct 1;12(5):497-501. doi: 10.1302/1863-2548.12.180029.


Cyclin-dependent kinase control of motile ciliogenesis.

Vladar EK, Stratton MB, Saal ML, Salazar-De Simone G, Wang X, Wolgemuth D, Stearns T, Axelrod JD.

Elife. 2018 Aug 28;7. pii: e36375. doi: 10.7554/eLife.36375.


P3 amplitude attenuation secondary to increases in target-to-target interval (TTI) during spatial serial order recall: implications for EEG models of working memory function.

Hochberger WC, Axelrod JL, Sarapas C, Shankman SA, Kristian Hill S.

Int J Neurosci. 2018 Dec;128(12):1135-1142. doi: 10.1080/00207454.2018.1486834. Epub 2018 Aug 20.


Interleukin-6 contributes to the increase in fibroblast growth factor 23 expression in acute and chronic kidney disease.

Durlacher-Betzer K, Hassan A, Levi R, Axelrod J, Silver J, Naveh-Many T.

Kidney Int. 2018 Aug;94(2):315-325. doi: 10.1016/j.kint.2018.02.026. Epub 2018 May 31.


FijiWingsPolarity: An open source toolkit for semi-automated detection of cell polarity.

Dobens LL, Shipman A, Axelrod JD.

Fly (Austin). 2018 Jan 2;12(1):23-33. doi: 10.1080/19336934.2017.1409927. Epub 2017 Dec 22.


Split2 Protein-Ligation Generates Active IL-6-Type Hyper-Cytokines from Inactive Precursors.

Moll JM, Wehmöller M, Frank NC, Homey L, Baran P, Garbers C, Lamertz L, Axelrod JH, Galun E, Mootz HD, Scheller J.

ACS Synth Biol. 2017 Dec 15;6(12):2260-2272. doi: 10.1021/acssynbio.7b00208. Epub 2017 Nov 29.


A Protective Function of IL-22BP in Ischemia Reperfusion and Acetaminophen-Induced Liver Injury.

Kleinschmidt D, Giannou AD, McGee HM, Kempski J, Steglich B, Huber FJ, Ernst TM, Shiri AM, Wegscheid C, Tasika E, Hübener P, Huber P, Bedke T, Steffens N, Agalioti T, Fuchs T, Noll J, Lotter H, Tiegs G, Lohse AW, Axelrod JH, Galun E, Flavell RA, Gagliani N, Huber S.

J Immunol. 2017 Dec 15;199(12):4078-4090. doi: 10.4049/jimmunol.1700587. Epub 2017 Nov 6.


Disruption of Core Planar Cell Polarity Signaling Regulates Renal Tubule Morphogenesis but Is Not Cystogenic.

Kunimoto K, Bayly RD, Vladar EK, Vonderfecht T, Gallagher AR, Axelrod JD.

Curr Biol. 2017 Oct 23;27(20):3120-3131.e4. doi: 10.1016/j.cub.2017.09.011. Epub 2017 Oct 12.


Functional outcomes following non-operative versus operative treatment of clavicle fractures in adolescents.

Herzog MM, Whitesell RC, Mac LM, Jackson ML, Culotta BA, Axelrod JR, Busch MT, Willimon SC.

J Child Orthop. 2017 Aug 1;11(4):310-317. doi: 10.1302/1863-2548.11.160267.


Pathways to Genome-targeted Therapies in Serous Ovarian Cancer.

Axelrod J, Delaney J.

J Nat Sci. 2017 Jul;3(7). pii: e408.


Near-concentric Fabry-Pérot cavity for continuous-wave laser control of electron waves.

Schwartz O, Axelrod JJ, Tuthill DR, Haslinger P, Ophus C, Glaeser RM, Müller H.

Opt Express. 2017 Jun 26;25(13):14453-14462. doi: 10.1364/OE.25.014453.


Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer.

Delaney JR, Patel CB, Willis KM, Haghighiabyaneh M, Axelrod J, Tancioni I, Lu D, Bapat J, Young S, Cadassou O, Bartakova A, Sheth P, Haft C, Hui S, Saenz C, Schlaepfer DD, Harismendy O, Stupack DG.

Nat Commun. 2017 Feb 15;8:14423. doi: 10.1038/ncomms14423.


Ritterostatin GN 1N , a Cephalostatin-Ritterazine Bis-steroidal Pyrazine Hybrid, Selectively Targets GRP78.

Ambrose AJ, Santos EA, Jimenez PC, Rocha DD, Wilke DV, Beuzer P, Axelrod J, Kumar Kanduluru A, Fuchs PL, Cang H, Costa-Lotufo LV, Chapman E, La Clair JJ.

Chembiochem. 2017 Mar 16;18(6):506-510. doi: 10.1002/cbic.201600669. Epub 2017 Feb 2.


Wnt Signaling in Chronic Rhinosinusitis with Nasal Polyps.

Böscke R, Vladar EK, Könnecke M, Hüsing B, Linke R, Pries R, Reiling N, Axelrod JD, Nayak JV, Wollenberg B.

Am J Respir Cell Mol Biol. 2017 May;56(5):575-584. doi: 10.1165/rcmb.2016-0024OC.


Interleukin 6-dependent genomic instability heralds accelerated carcinogenesis following liver regeneration on a background of chronic hepatitis.

Lanton T, Shriki A, Nechemia-Arbely Y, Abramovitch R, Levkovitch O, Adar R, Rosenberg N, Paldor M, Goldenberg D, Sonnenblick A, Peled A, Rose-John S, Galun E, Axelrod JH.

Hepatology. 2017 May;65(5):1600-1611. doi: 10.1002/hep.29004. Epub 2017 Mar 23.


Airway epithelial homeostasis and planar cell polarity signaling depend on multiciliated cell differentiation.

Vladar EK, Nayak JV, Milla CE, Axelrod JD.

JCI Insight. 2016 Aug 18;1(13). pii: e88027.


Single dish gradient screening of small molecule localization.

Beuzer P, Axelrod J, Trzoss L, Fenical W, Dasari R, Evidente A, Kornienko A, Cang H, La Clair JJ.

Org Biomol Chem. 2016 Sep 21;14(35):8241-5. doi: 10.1039/c6ob01418f. Epub 2016 Aug 17.


The Phenotypic Effects of Royal Jelly on Wild-Type D. melanogaster Are Strain-Specific.

Morgan SL, Seggio JA, Nascimento NF, Huh DD, Hicks JA, Sharp KA, Axelrod JD, Wang KC.

PLoS One. 2016 Aug 3;11(8):e0159456. doi: 10.1371/journal.pone.0159456. eCollection 2016.


Prickle1 mutation causes planar cell polarity and directional cell migration defects associated with cardiac outflow tract anomalies and other structural birth defects.

Gibbs BC, Damerla RR, Vladar EK, Chatterjee B, Wan Y, Liu X, Cui C, Gabriel GC, Zahid M, Yagi H, Szabo-Rogers HL, Suyama KL, Axelrod JD, Lo CW.

Biol Open. 2016 Feb 16;5(3):323-35. doi: 10.1242/bio.015750.


Prickle isoforms control the direction of tissue polarity by microtubule independent and dependent mechanisms.

Sharp KA, Axelrod JD.

Biol Open. 2016 Feb 10;5(3):229-36. doi: 10.1242/bio.016162.


Radiation-Induced Loss of Salivary Gland Function Is Driven by Cellular Senescence and Prevented by IL6 Modulation.

Marmary Y, Adar R, Gaska S, Wygoda A, Maly A, Cohen J, Eliashar R, Mizrachi L, Orfaig-Geva C, Baum BJ, Rose-John S, Galun E, Axelrod JH.

Cancer Res. 2016 Mar 1;76(5):1170-80. doi: 10.1158/0008-5472.CAN-15-1671. Epub 2016 Jan 12. Erratum in: Cancer Res. 2016 May 1;76(9):2846.


Sorafenib treatment during partial hepatectomy reduces tumorgenesis in an inflammation-associated liver cancer model.

Zahavi T, Lanton T, Divon MS, Salmon A, Peretz T, Galun E, Axelrod JH, Sonnenblick A.

Oncotarget. 2016 Jan 26;7(4):4860-70. doi: 10.18632/oncotarget.6638.


Clustering and negative feedback by endocytosis in planar cell polarity signaling is modulated by ubiquitinylation of prickle.

Cho B, Pierre-Louis G, Sagner A, Eaton S, Axelrod JD.

PLoS Genet. 2015 May 21;11(5):e1005259. doi: 10.1371/journal.pgen.1005259. eCollection 2015 May.


Observing planar cell polarity in multiciliated mouse airway epithelial cells.

Vladar EK, Lee YL, Stearns T, Axelrod JD.

Methods Cell Biol. 2015;127:37-54. doi: 10.1016/bs.mcb.2015.01.016. Epub 2015 Mar 7.


Endothelin-converting enzyme is a plausible target gene for hypoxia-inducible factor.

Khamaisi M, Toukan H, Axelrod JH, Rosenberger C, Skarzinski G, Shina A, Meidan R, Koesters R, Rosen S, Walkinshaw G, Mimura I, Nangaku M, Heyman SN.

Kidney Int. 2015 Apr;87(4):761-70. doi: 10.1038/ki.2014.362. Epub 2014 Dec 3.


Triggering necroptosis in cisplatin and IAP antagonist-resistant ovarian carcinoma.

McCabe KE, Bacos K, Lu D, Delaney JR, Axelrod J, Potter MD, Vamos M, Wong V, Cosford ND, Xiang R, Stupack DG.

Cell Death Dis. 2014 Oct 30;5:e1496. doi: 10.1038/cddis.2014.448.


Coordinating cell polarity: heading in the right direction?

Axelrod JD, Bergmann DC.

Development. 2014 Sep;141(17):3298-302. doi: 10.1242/dev.111484.


Microtubules provide directional information for core PCP function.

Matis M, Russler-Germain DA, Hu Q, Tomlin CJ, Axelrod JD.

Elife. 2014 Aug 14;3:e02893. doi: 10.7554/eLife.02893.


prickle modulates microtubule polarity and axonal transport to ameliorate seizures in flies.

Ehaideb SN, Iyengar A, Ueda A, Iacobucci GJ, Cranston C, Bassuk AG, Gubb D, Axelrod JD, Gunawardena S, Wu CF, Manak JR.

Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11187-92. doi: 10.1073/pnas.1403357111. Epub 2014 Jul 14.


Prickle/spiny-legs isoforms control the polarity of the apical microtubule network in planar cell polarity.

Olofsson J, Sharp KA, Matis M, Cho B, Axelrod JD.

Development. 2014 Jul;141(14):2866-74. doi: 10.1242/dev.105932.


Methods for studying planar cell polarity.

Olofsson J, Axelrod JD.

Methods. 2014 Jun 15;68(1):97-104. doi: 10.1016/j.ymeth.2014.03.017. Epub 2014 Mar 27. Review.


Assessment with unenhanced MRI techniques of renal morphology and hemodynamic changes during acute kidney injury and chronic kidney disease in mice.

Milman Z, Axelrod JH, Heyman SN, Nachmansson N, Abramovitch R.

Am J Nephrol. 2014;39(3):268-78. doi: 10.1159/000360093. Epub 2014 Mar 21.


Metabolomics of the tumor microenvironment in pediatric acute lymphoblastic leukemia.

Tiziani S, Kang Y, Harjanto R, Axelrod J, Piermarocchi C, Roberts W, Paternostro G.

PLoS One. 2013 Dec 13;8(12):e82859. doi: 10.1371/journal.pone.0082859. eCollection 2013.


Natural killer cell-dependent anti-fibrotic pathway in liver injury via Toll-like receptor-9.

Abu-Tair L, Axelrod JH, Doron S, Ovadya Y, Krizhanovsky V, Galun E, Amer J, Safadi R.

PLoS One. 2013 Dec 10;8(12):e82571. doi: 10.1371/journal.pone.0082571. eCollection 2013.


Regulation of PCP by the Fat signaling pathway.

Matis M, Axelrod JD.

Genes Dev. 2013 Oct 15;27(20):2207-20. doi: 10.1101/gad.228098.113. Review.


Myb promotes centriole amplification and later steps of the multiciliogenesis program.

Tan FE, Vladar EK, Ma L, Fuentealba LC, Hoh R, Espinoza FH, Axelrod JD, Alvarez-Buylla A, Stearns T, Kintner C, Krasnow MA.

Development. 2013 Oct;140(20):4277-86. doi: 10.1242/dev.094102. Epub 2013 Sep 18.


Absolute requirement of cholesterol binding for Hedgehog gradient formation in Drosophila.

Ducuing A, Mollereau B, Axelrod JD, Vincent S.

Biol Open. 2013 May 9;2(6):596-604. doi: 10.1242/bio.20134952. Print 2013 Jun 15.


Inflammation-induced hepatocellular carcinoma is dependent on CCR5 in mice.

Barashi N, Weiss ID, Wald O, Wald H, Beider K, Abraham M, Klein S, Goldenberg D, Axelrod J, Pikarsky E, Abramovitch R, Zeira E, Galun E, Peled A.

Hepatology. 2013 Sep;58(3):1021-30. doi: 10.1002/hep.26403. Epub 2013 Jul 12.


Tumor STAT3 tyrosine phosphorylation status, as a predictor of benefit from adjuvant chemotherapy for breast cancer.

Sonnenblick A, Uziely B, Nechushtan H, Kadouri L, Galun E, Axelrod JH, Katz D, Daum H, Hamburger T, Maly B, Allweis TM, Peretz T.

Breast Cancer Res Treat. 2013 Apr;138(2):407-13. doi: 10.1007/s10549-013-2453-x. Epub 2013 Feb 28.


In vivo evidence suggesting reciprocal renal hypoxia-inducible factor-1 upregulation and signal transducer and activator of transcription 3 activation in response to hypoxic and non-hypoxic stimuli.

Nechemia-Arbely Y, Khamaisi M, Rosenberger C, Koesters R, Shina A, Geva C, Shriki A, Klaus S, Rosen S, Rose-John S, Galun E, Axelrod JH, Heyman SN.

Clin Exp Pharmacol Physiol. 2013 Apr;40(4):262-72. doi: 10.1111/1440-1681.12064.


Hemodynamic response magnetic resonance imaging: application for renal hemodynamic characterization.

Milman Z, Heyman SN, Corchia N, Edrei Y, Axelrod JH, Rosenberger C, Tsarfati G, Abramovitch R.

Nephrol Dial Transplant. 2013 May;28(5):1150-6. doi: 10.1093/ndt/gfs541. Epub 2013 Jan 4.


A mathematical model to study the dynamics of epithelial cellular networks.

Abate A, Vincent S, Dobbe R, Silletti A, Master N, Axelrod JD, Tomlin CJ.

IEEE/ACM Trans Comput Biol Bioinform. 2012 Nov-Dec;9(6):1607-20. doi: 10.1109/TCBB.2012.126.


Remodeling a tissue: subtraction adds insight.

Axelrod JD.

Sci Signal. 2012 Nov 27;5(252):pe52. doi: 10.1126/scisignal.2003620. Review.


Asymmetric protein localization in planar cell polarity: mechanisms, puzzles, and challenges.

Peng Y, Axelrod JD.

Curr Top Dev Biol. 2012;101:33-53. doi: 10.1016/B978-0-12-394592-1.00002-8. Review.


Microtubules enable the planar cell polarity of airway cilia.

Vladar EK, Bayly RD, Sangoram AM, Scott MP, Axelrod JD.

Curr Biol. 2012 Dec 4;22(23):2203-12. doi: 10.1016/j.cub.2012.09.046. Epub 2012 Nov 1.


Planar polarized protrusions break the symmetry of EGFR signaling during Drosophila bract cell fate induction.

Peng Y, Han C, Axelrod JD.

Dev Cell. 2012 Sep 11;23(3):507-18. doi: 10.1016/j.devcel.2012.07.016. Epub 2012 Aug 23.


A universal analysis tool for the detection of asymmetric signal distribution in microscopic images.

Matis M, Axelrod JD, Galic M.

Dev Dyn. 2012 Aug;241(8):1301-9. doi: 10.1002/dvdy.23818. Epub 2012 Jun 23.


Tissue microarray-based study of patients with lymph node-positive breast cancer shows tyrosine phosphorylation of signal transducer and activator of transcription 3 (tyrosine705-STAT3) is a marker of good prognosis.

Sonnenblick A, Shriki A, Galun E, Axelrod JH, Daum H, Rottenberg Y, Hamburger T, Mali B, Peretz T.

Clin Transl Oncol. 2012 Mar;14(3):232-6. doi: 10.1007/s12094-012-0789-z.


Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis.

Tao H, Inoue K, Kiyonari H, Bassuk AG, Axelrod JD, Sasaki H, Aizawa S, Ueno N.

Dev Biol. 2012 Apr 15;364(2):138-48. doi: 10.1016/j.ydbio.2012.01.025. Epub 2012 Feb 4.


Multicilin promotes centriole assembly and ciliogenesis during multiciliate cell differentiation.

Stubbs JL, Vladar EK, Axelrod JD, Kintner C.

Nat Cell Biol. 2012 Jan 8;14(2):140-7. doi: 10.1038/ncb2406.

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