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Items: 1 to 50 of 98

1.

Epigenetic Silencing of THY1 Tracks the Acquisition of the Notch1-EGFR Signaling in a Xenograft Model of CD44+/CD24low/CD90+ Myoepithelial Cells.

Montanari M, Carbone MR, Coppola L, Giuliano M, Arpino G, Lauria R, Nardone A, Leccia F, Trivedi MV, Garbi C, Bianco R, Avvedimento EV, De Placido S, Veneziani BM.

Mol Cancer Res. 2018 Sep 21. doi: 10.1158/1541-7786.MCR-17-0324. [Epub ahead of print]

PMID:
30242055
2.

Reply.

Luchetti MM, Moroncini G, Svegliati S, Larcher F, Avvedimento EV, Gabrielli A.

Arthritis Rheumatol. 2017 Aug;69(8):1703-1704. doi: 10.1002/art.40138. Epub 2017 Jun 14. No abstract available.

3.

High-coverage methylation data of a gene model before and after DNA damage and homologous repair.

Pezone A, Russo G, Tramontano A, Florio E, Scala G, Landi R, Zuchegna C, Romano A, Chiariotti L, Muller MT, Gottesman ME, Porcellini A, Avvedimento EV.

Sci Data. 2017 Apr 11;4:170043. doi: 10.1038/sdata.2017.43.

4.

Correction: DNA Damage, Homology-Directed Repair, and DNA Methylation.

Cuozzo C, Porcellini A, Angrisano T, Morano A, Lee B, Pardo AD, Messina S, Iuliano R, Fusco A, Santillo MR, Muller MT, Chiariotti L, Gottesman ME, Avvedimento EV.

PLoS Genet. 2017 Feb 10;13(2):e1006605. doi: 10.1371/journal.pgen.1006605. eCollection 2017 Feb.

5.

DNA damage and Repair Modify DNA methylation and Chromatin Domain of the Targeted Locus: Mechanism of allele methylation polymorphism.

Russo G, Landi R, Pezone A, Morano A, Zuchegna C, Romano A, Muller MT, Gottesman ME, Porcellini A, Avvedimento EV.

Sci Rep. 2016 Sep 15;6:33222. doi: 10.1038/srep33222.

6.

Reactive Oxygen Species Derived from NOX3 and NOX5 Drive Differentiation of Human Oligodendrocytes.

Accetta R, Damiano S, Morano A, Mondola P, Paternò R, Avvedimento EV, Santillo M.

Front Cell Neurosci. 2016 Jun 2;10:146. doi: 10.3389/fncel.2016.00146. eCollection 2016.

7.

Induction of Scleroderma Fibrosis in Skin-Humanized Mice by Administration of Anti-Platelet-Derived Growth Factor Receptor Agonistic Autoantibodies.

Luchetti MM, Moroncini G, Jose Escamez M, Svegliati Baroni S, Spadoni T, Grieco A, Paolini C, Funaro A, Avvedimento EV, Larcher F, Del Rio M, Gabrielli A.

Arthritis Rheumatol. 2016 Sep;68(9):2263-73. doi: 10.1002/art.39728.

8.

Epitope Specificity Determines Pathogenicity and Detectability of Anti-Platelet-Derived Growth Factor Receptor α Autoantibodies in Systemic Sclerosis.

Moroncini G, Grieco A, Nacci G, Paolini C, Tonnini C, Pozniak KN, Cuccioloni M, Mozzicafreddo M, Svegliati S, Angeletti M, Kazlauskas A, Avvedimento EV, Funaro A, Gabrielli A.

Arthritis Rheumatol. 2015 Jul;67(7):1891-903. doi: 10.1002/art.39125.

9.

A reactive oxygen species-mediated loop maintains increased expression of NADPH oxidases 2 and 4 in skin fibroblasts from patients with systemic sclerosis.

Spadoni T, Svegliati Baroni S, Amico D, Albani L, Moroncini G, Avvedimento EV, Gabrielli A.

Arthritis Rheumatol. 2015 Jun;67(6):1611-22. doi: 10.1002/art.39084.

10.

Mechanism of retinoic acid-induced transcription: histone code, DNA oxidation and formation of chromatin loops.

Zuchegna C, Aceto F, Bertoni A, Romano A, Perillo B, Laccetti P, Gottesman ME, Avvedimento EV, Porcellini A.

Nucleic Acids Res. 2014;42(17):11040-55. doi: 10.1093/nar/gku823. Epub 2014 Sep 12. Erratum in: Nucleic Acids Res. 2014 Oct 29;42(19):12329.

11.

Oxidative DNA damage induces the ATM-mediated transcriptional suppression of the Wnt inhibitor WIF-1 in systemic sclerosis and fibrosis.

Svegliati S, Marrone G, Pezone A, Spadoni T, Grieco A, Moroncini G, Grieco D, Vinciguerra M, Agnese S, Jüngel A, Distler O, Musti AM, Gabrielli A, Avvedimento EV.

Sci Signal. 2014 Sep 2;7(341):ra84. doi: 10.1126/scisignal.2004592.

PMID:
25185156
12.

Epigenetic switch at atp2a2 and myh7 gene promoters in pressure overload-induced heart failure.

Angrisano T, Schiattarella GG, Keller S, Pironti G, Florio E, Magliulo F, Bottino R, Pero R, Lembo F, Avvedimento EV, Esposito G, Trimarco B, Chiariotti L, Perrino C.

PLoS One. 2014 Sep 2;9(9):e106024. doi: 10.1371/journal.pone.0106024. eCollection 2014.

13.

Targeted DNA methylation by homology-directed repair in mammalian cells. Transcription reshapes methylation on the repaired gene.

Morano A, Angrisano T, Russo G, Landi R, Pezone A, Bartollino S, Zuchegna C, Babbio F, Bonapace IM, Allen B, Muller MT, Chiariotti L, Gottesman ME, Porcellini A, Avvedimento EV.

Nucleic Acids Res. 2014 Jan;42(2):804-21. doi: 10.1093/nar/gkt920. Epub 2013 Oct 16.

14.

Retinoic acid impairs estrogen signaling in breast cancer cells by interfering with activation of LSD1 via PKA.

Ombra MN, Di Santi A, Abbondanza C, Migliaccio A, Avvedimento EV, Perillo B.

Biochim Biophys Acta. 2013 May;1829(5):480-6. doi: 10.1016/j.bbagrm.2013.03.003. Epub 2013 Mar 16.

PMID:
23507259
15.

Identification of novel AR-targeted microRNAs mediating androgen signalling through critical pathways to regulate cell viability in prostate cancer.

Mo W, Zhang J, Li X, Meng D, Gao Y, Yang S, Wan X, Zhou C, Guo F, Huang Y, Amente S, Avvedimento EV, Xie Y, Li Y.

PLoS One. 2013;8(2):e56592. doi: 10.1371/journal.pone.0056592. Epub 2013 Feb 22.

16.

Systemic sclerosis (scleroderma) and cancer risk: systematic review and meta-analysis of observational studies.

Bonifazi M, Tramacere I, Pomponio G, Gabrielli B, Avvedimento EV, La Vecchia C, Negri E, Gabrielli A.

Rheumatology (Oxford). 2013 Jan;52(1):143-54. doi: 10.1093/rheumatology/kes303. Epub 2012 Nov 22. Review.

PMID:
23175568
17.

Reactive oxygen species regulate the levels of dual oxidase (Duox1-2) in human neuroblastoma cells.

Damiano S, Fusco R, Morano A, De Mizio M, Paternò R, De Rosa A, Spinelli R, Amente S, Frunzio R, Mondola P, Miot F, Laccetti P, Santillo M, Avvedimento EV.

PLoS One. 2012;7(4):e34405. doi: 10.1371/journal.pone.0034405. Epub 2012 Apr 16.

18.

The p85α regulatory subunit of PI3K mediates cAMP-PKA and retinoic acid biological effects on MCF7 cell growth and migration.

Donini CF, Di Zazzo E, Zuchegna C, Di Domenico M, D'Inzeo S, Nicolussi A, Avvedimento EV, Coppa A, Porcellini A.

Int J Oncol. 2012 May;40(5):1627-35. doi: 10.3892/ijo.2012.1383. Epub 2012 Feb 21.

PMID:
22366926
19.

The aging effect of chemotherapy on cultured human mesenchymal stem cells.

Buttiglieri S, Ruella M, Risso A, Spatola T, Silengo L, Avvedimento EV, Tarella C.

Exp Hematol. 2011 Dec;39(12):1171-81. doi: 10.1016/j.exphem.2011.08.009. Epub 2011 Aug 22.

PMID:
21864489
20.

Myc and PI3K/AKT signaling cooperatively repress FOXO3a-dependent PUMA and GADD45a gene expression.

Amente S, Zhang J, Lavadera ML, Lania L, Avvedimento EV, Majello B.

Nucleic Acids Res. 2011 Dec;39(22):9498-507. doi: 10.1093/nar/gkr638. Epub 2011 Aug 10. Erratum in: Nucleic Acids Res. 2014 Feb;42(3):2098.

21.

Highlighting chromosome loops in DNA-picked chromatin (DPC).

Abbondanza C, De Rosa C, Ombra MN, Aceto F, Medici N, Altucci L, Moncharmont B, Puca GA, Porcellini A, Avvedimento EV, Perillo B.

Epigenetics. 2011 Aug;6(8):979-86. doi: 10.4161/epi.6.8.16060. Epub 2011 Aug 1.

PMID:
21725198
22.

Reactive oxygen species are required for maintenance and differentiation of primary lung fibroblasts in idiopathic pulmonary fibrosis.

Bocchino M, Agnese S, Fagone E, Svegliati S, Grieco D, Vancheri C, Gabrielli A, Sanduzzi A, Avvedimento EV.

PLoS One. 2010 Nov 16;5(11):e14003. doi: 10.1371/journal.pone.0014003.

23.

DNA oxidation drives Myc mediated transcription.

Amente S, Lania L, Avvedimento EV, Majello B.

Cell Cycle. 2010 Aug 1;9(15):3002-4. doi: 10.4161/cc.9.15.12499. Review.

PMID:
20714214
24.

Reactive oxygen species, Ki-Ras, and mitochondrial superoxide dismutase cooperate in nerve growth factor-induced differentiation of PC12 cells.

Cassano S, Agnese S, D'Amato V, Papale M, Garbi C, Castagnola P, Ruocco MR, Castellano I, De Vendittis E, Santillo M, Amente S, Porcellini A, Avvedimento EV.

J Biol Chem. 2010 Jul 30;285(31):24141-53. doi: 10.1074/jbc.M109.098525. Epub 2010 May 21.

25.

LSD1-mediated demethylation of histone H3 lysine 4 triggers Myc-induced transcription.

Amente S, Bertoni A, Morano A, Lania L, Avvedimento EV, Majello B.

Oncogene. 2010 Jun 24;29(25):3691-702. doi: 10.1038/onc.2010.120. Epub 2010 Apr 26.

PMID:
20418916
26.

Stiff and tight skin: a rear window into fibrosis without inflammation.

Avvedimento EV, Gabrielli A.

Sci Transl Med. 2010 Mar 17;2(23):23ps13. doi: 10.1126/scitranslmed.3000949.

PMID:
20375002
27.

Autoantibodies against the platelet-derived growth factor receptor in scleroderma: comment on the articles by Classen et al and Loizos et al.

Gabrielli A, Moroncini G, Svegliati S, Avvedimento EV.

Arthritis Rheum. 2009 Nov;60(11):3521-2. doi: 10.1002/art.27209. No abstract available.

28.

Differential regulation of vascular smooth muscle and endothelial cell proliferation in vitro and in vivo by cAMP/PKA-activated p85alphaPI3K.

Torella D, Gasparri C, Ellison GM, Curcio A, Leone A, Vicinanza C, Galuppo V, Mendicino I, Sacco W, Aquila I, Surace FC, Luposella M, Stillo G, Agosti V, Cosentino C, Avvedimento EV, Indolfi C.

Am J Physiol Heart Circ Physiol. 2009 Dec;297(6):H2015-25. doi: 10.1152/ajpheart.00738.2009. Epub 2009 Sep 25.

29.

Scleroderma.

Gabrielli A, Avvedimento EV, Krieg T.

N Engl J Med. 2009 May 7;360(19):1989-2003. doi: 10.1056/NEJMra0806188. Review. No abstract available.

PMID:
19420368
30.

Rat mitochondrial manganese superoxide dismutase: amino acid positions involved in covalent modifications, activity, and heat stability.

Castellano I, Cecere F, De Vendittis A, Cotugno R, Chambery A, Di Maro A, Michniewicz A, Parlato G, Masullo M, Avvedimento EV, De Vendittis E, Ruocco MR.

Biopolymers. 2009 Dec;91(12):1215-26. doi: 10.1002/bip.21208.

PMID:
19384983
31.

Oxidative stress and the pathogenesis of scleroderma: the Murrell's hypothesis revisited.

Gabrielli A, Svegliati S, Moroncini G, Pomponio G, Santillo M, Avvedimento EV.

Semin Immunopathol. 2008 Jul;30(3):329-37. doi: 10.1007/s00281-008-0125-4. Epub 2008 Jun 12. Review.

PMID:
18548250
32.

Protein-tyrosine phosphatase PTPD1 regulates focal adhesion kinase autophosphorylation and cell migration.

Carlucci A, Gedressi C, Lignitto L, Nezi L, Villa-Moruzzi E, Avvedimento EV, Gottesman M, Garbi C, Feliciello A.

J Biol Chem. 2008 Apr 18;283(16):10919-29. doi: 10.1074/jbc.M707248200. Epub 2008 Jan 26.

33.

DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression.

Perillo B, Ombra MN, Bertoni A, Cuozzo C, Sacchetti S, Sasso A, Chiariotti L, Malorni A, Abbondanza C, Avvedimento EV.

Science. 2008 Jan 11;319(5860):202-6. doi: 10.1126/science.1147674.

34.

Pathogenic autoantibodies in systemic sclerosis.

Gabrielli A, Svegliati S, Moroncini G, Avvedimento EV.

Curr Opin Immunol. 2007 Dec;19(6):640-5. Review.

PMID:
18083509
35.

Stimulatory autoantibodies to the PDGF receptor: a link to fibrosis in scleroderma and a pathway for novel therapeutic targets.

Gabrielli A, Svegliati S, Moroncini G, Luchetti M, Tonnini C, Avvedimento EV.

Autoimmun Rev. 2007 Dec;7(2):121-6. Epub 2007 Mar 28. Review.

PMID:
18035321
36.

Farnesyl transferase inhibitors induce neuroprotection by inhibiting Ha-Ras signalling pathway.

Ruocco A, Santillo M, Cicale M, Serù R, Cuda G, Anrather J, Iadecola C, Postiglione A, Avvedimento EV, Paternò R.

Eur J Neurosci. 2007 Dec;26(11):3261-6. Epub 2007 Nov 14.

PMID:
18005061
37.

DNA damage, homology-directed repair, and DNA methylation.

Cuozzo C, Porcellini A, Angrisano T, Morano A, Lee B, Di Pardo A, Messina S, Iuliano R, Fusco A, Santillo MR, Muller MT, Chiariotti L, Gottesman ME, Avvedimento EV.

PLoS Genet. 2007 Jul;3(7):e110. Erratum in: PLoS Genet. 2017 Feb 10;13(2):e1006605.

38.

Stimulatory autoantibodies to PDGF receptor in patients with extensive chronic graft-versus-host disease.

Svegliati S, Olivieri A, Campelli N, Luchetti M, Poloni A, Trappolini S, Moroncini G, Bacigalupo A, Leoni P, Avvedimento EV, Gabrielli A.

Blood. 2007 Jul 1;110(1):237-41. Epub 2007 Mar 15.

39.

The p85 regulatory subunit of PI3K mediates TSH-cAMP-PKA growth and survival signals.

De Gregorio G, Coppa A, Cosentino C, Ucci S, Messina S, Nicolussi A, D'Inzeo S, Di Pardo A, Avvedimento EV, Porcellini A.

Oncogene. 2007 Mar 29;26(14):2039-47. Epub 2006 Oct 9.

PMID:
17043656
40.

p85 regulatory subunit of PI3K mediates cAMP-PKA and estrogens biological effects on growth and survival.

Cosentino C, Di Domenico M, Porcellini A, Cuozzo C, De Gregorio G, Santillo MR, Agnese S, Di Stasio R, Feliciello A, Migliaccio A, Avvedimento EV.

Oncogene. 2007 Mar 29;26(14):2095-103. Epub 2006 Oct 2.

PMID:
17016431
41.

Stimulatory autoantibodies to the PDGF receptor in systemic sclerosis.

Baroni SS, Santillo M, Bevilacqua F, Luchetti M, Spadoni T, Mancini M, Fraticelli P, Sambo P, Funaro A, Kazlauskas A, Avvedimento EV, Gabrielli A.

N Engl J Med. 2006 Jun 22;354(25):2667-76.

42.

Inhibition of Ras/ERK1/2 signaling protects against postischemic renal injury.

Sabbatini M, Santillo M, Pisani A, Paternò R, Uccello F, Serù R, Matrone G, Spagnuolo G, Andreucci M, Serio V, Esposito P, Cianciaruso B, Fuiano G, Avvedimento EV.

Am J Physiol Renal Physiol. 2006 Jun;290(6):F1408-15. Epub 2006 Jan 24.

43.

Mitochondrial AKAP121 links cAMP and src signaling to oxidative metabolism.

Livigni A, Scorziello A, Agnese S, Adornetto A, Carlucci A, Garbi C, Castaldo I, Annunziato L, Avvedimento EV, Feliciello A.

Mol Biol Cell. 2006 Jan;17(1):263-71. Epub 2005 Oct 26.

44.

Platelet-derived growth factor and reactive oxygen species (ROS) regulate Ras protein levels in primary human fibroblasts via ERK1/2. Amplification of ROS and Ras in systemic sclerosis fibroblasts.

Svegliati S, Cancello R, Sambo P, Luchetti M, Paroncini P, Orlandini G, Discepoli G, Paterno R, Santillo M, Cuozzo C, Cassano S, Avvedimento EV, Gabrielli A.

J Biol Chem. 2005 Oct 28;280(43):36474-82. Epub 2005 Aug 4.

45.

cAMP-PKA signaling to the mitochondria: protein scaffolds, mRNA and phosphatases.

Feliciello A, Gottesman ME, Avvedimento EV.

Cell Signal. 2005 Mar;17(3):279-87. Review.

PMID:
15567059
46.

NF-kappaB protection against apoptosis induced by HEMA.

Spagnuolo G, Mauro C, Leonardi A, Santillo M, Paternò R, Schweikl H, Avvedimento EV, Rengo S.

J Dent Res. 2004 Nov;83(11):837-42.

PMID:
15505232
47.

HaRas activates the NADPH oxidase complex in human neuroblastoma cells via extracellular signal-regulated kinase 1/2 pathway.

Serù R, Mondola P, Damiano S, Svegliati S, Agnese S, Avvedimento EV, Santillo M.

J Neurochem. 2004 Nov;91(3):613-22.

48.

Transient and reversible deoxyribonucleic acid damage in human left ventricle under controlled ischemia and reperfusion.

Corbucci GG, Perrino C, Donato G, Ricchi A, Lettieri B, Troncone G, Indolfi C, Chiariello M, Avvedimento EV.

J Am Coll Cardiol. 2004 Jun 2;43(11):1992-9.

49.

Mitochondrial AKAP121 binds and targets protein tyrosine phosphatase D1, a novel positive regulator of src signaling.

Cardone L, Carlucci A, Affaitati A, Livigni A, DeCristofaro T, Garbi C, Varrone S, Ullrich A, Gottesman ME, Avvedimento EV, Feliciello A.

Mol Cell Biol. 2004 Jun;24(11):4613-26.

50.

DNA damage induced by polyglutamine-expanded proteins.

Giuliano P, De Cristofaro T, Affaitati A, Pizzulo GM, Feliciello A, Criscuolo C, De Michele G, Filla A, Avvedimento EV, Varrone S.

Hum Mol Genet. 2003 Sep 15;12(18):2301-9. Epub 2003 Jul 22.

PMID:
12915485

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