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Items: 1 to 50 of 60

1.

A strategy for modulation of enzymes in the ubiquitin system.

Ernst A, Avvakumov G, Tong J, Fan Y, Zhao Y, Alberts P, Persaud A, Walker JR, Neculai AM, Neculai D, Vorobyov A, Garg P, Beatty L, Chan PK, Juang YC, Landry MC, Yeh C, Zeqiraj E, Karamboulas K, Allali-Hassani A, Vedadi M, Tyers M, Moffat J, Sicheri F, Pelletier L, Durocher D, Raught B, Rotin D, Yang J, Moran MF, Dhe-Paganon S, Sidhu SS.

Science. 2013 Feb 1;339(6119):590-5. doi: 10.1126/science.1230161. Epub 2013 Jan 3.

2.

A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.

Sheng Y, Hong JH, Doherty R, Srikumar T, Shloush J, Avvakumov GV, Walker JR, Xue S, Neculai D, Wan JW, Kim SK, Arrowsmith CH, Raught B, Dhe-Paganon S.

Mol Cell Proteomics. 2012 Aug;11(8):329-41. doi: 10.1074/mcp.O111.013706. Epub 2012 Apr 10.

3.

Two ZnF-UBP domains in isopeptidase T (USP5).

Avvakumov GV, Walker JR, Xue S, Allali-Hassani A, Asinas A, Nair UB, Fang X, Zuo X, Wang YX, Wilkinson KD, Dhe-Paganon S.

Biochemistry. 2012 Feb 14;51(6):1188-98. doi: 10.1021/bi200854q. Epub 2012 Feb 3.

PMID:
22283393
4.

Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein.

Nady N, Lemak A, Walker JR, Avvakumov GV, Kareta MS, Achour M, Xue S, Duan S, Allali-Hassani A, Zuo X, Wang YX, Bronner C, Chédin F, Arrowsmith CH, Dhe-Paganon S.

J Biol Chem. 2011 Jul 8;286(27):24300-11. doi: 10.1074/jbc.M111.234104. Epub 2011 Apr 13.

5.

The replication focus targeting sequence (RFTS) domain is a DNA-competitive inhibitor of Dnmt1.

Syeda F, Fagan RL, Wean M, Avvakumov GV, Walker JR, Xue S, Dhe-Paganon S, Brenner C.

J Biol Chem. 2011 Apr 29;286(17):15344-51. doi: 10.1074/jbc.M110.209882. Epub 2011 Mar 9.

6.

Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity.

Ko S, Kang GB, Song SM, Lee JG, Shin DY, Yun JH, Sheng Y, Cheong C, Jeon YH, Jung YK, Arrowsmith CH, Avvakumov GV, Dhe-Paganon S, Yoo YJ, Eom SH, Lee W.

J Biol Chem. 2010 Nov 12;285(46):36070-80. doi: 10.1074/jbc.M110.145219. Epub 2010 Sep 8.

7.

Structural analyses of sex hormone-binding globulin reveal novel ligands and function.

Avvakumov GV, Cherkasov A, Muller YA, Hammond GL.

Mol Cell Endocrinol. 2010 Mar 5;316(1):13-23. doi: 10.1016/j.mce.2009.09.005. Epub 2009 Sep 11. Review.

PMID:
19748550
8.

Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1.

Avvakumov GV, Walker JR, Xue S, Li Y, Duan S, Bronner C, Arrowsmith CH, Dhe-Paganon S.

Nature. 2008 Oct 9;455(7214):822-5. doi: 10.1038/nature07273. Epub 2008 Sep 3.

PMID:
18772889
9.

In situ proteolysis for protein crystallization and structure determination.

Dong A, Xu X, Edwards AM; Midwest Center for Structural Genomics; Structural Genomics Consortium, Chang C, Chruszcz M, Cuff M, Cymborowski M, Di Leo R, Egorova O, Evdokimova E, Filippova E, Gu J, Guthrie J, Ignatchenko A, Joachimiak A, Klostermann N, Kim Y, Korniyenko Y, Minor W, Que Q, Savchenko A, Skarina T, Tan K, Yakunin A, Yee A, Yim V, Zhang R, Zheng H, Akutsu M, Arrowsmith C, Avvakumov GV, Bochkarev A, Dahlgren LG, Dhe-Paganon S, Dimov S, Dombrovski L, Finerty P Jr, Flodin S, Flores A, Gräslund S, Hammerström M, Herman MD, Hong BS, Hui R, Johansson I, Liu Y, Nilsson M, Nedyalkova L, Nordlund P, Nyman T, Min J, Ouyang H, Park HW, Qi C, Rabeh W, Shen L, Shen Y, Sukumard D, Tempel W, Tong Y, Tresagues L, Vedadi M, Walker JR, Weigelt J, Welin M, Wu H, Xiao T, Zeng H, Zhu H.

Nat Methods. 2007 Dec;4(12):1019-21. Epub 2007 Nov 4.

10.

Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8).

Avvakumov GV, Walker JR, Xue S, Finerty PJ Jr, Mackenzie F, Newman EM, Dhe-Paganon S.

J Biol Chem. 2006 Dec 8;281(49):38061-70. Epub 2006 Oct 11.

11.

Evidence that fibulin family members contribute to the steroid-dependent extravascular sequestration of sex hormone-binding globulin.

Ng KM, Catalano MG, Pinós T, Selva DM, Avvakumov GV, Munell F, Hammond GL.

J Biol Chem. 2006 Jun 9;281(23):15853-61. Epub 2006 Apr 6.

12.

Sea bass (Dicentrarchus labrax) sex hormone binding globulin: molecular and biochemical properties and phylogenetic comparison of its orthologues in multiple fish species.

Miguel-Queralt S, Avvakumov GV, Blázquez M, Piferrer F, Hammond GL.

Mol Cell Endocrinol. 2005 Jan 14;229(1-2):21-9.

PMID:
15607525
13.

Molecular and functional characterization of sex hormone binding globulin in zebrafish.

Miguel-Queralt S, Knowlton M, Avvakumov GV, Al-Nouno R, Kelly GM, Hammond GL.

Endocrinology. 2004 Nov;145(11):5221-30. Epub 2004 Jul 29.

PMID:
15284198
14.

Structure/function analyses of human sex hormone-binding globulin: effects of zinc on steroid-binding specificity.

Hammond GL, Avvakumov GV, Muller YA.

J Steroid Biochem Mol Biol. 2003 Jun;85(2-5):195-200. Review.

PMID:
12943704
15.
16.

18F-labeled difluoroestradiols: preparation and preclinical evaluation as estrogen receptor-binding radiopharmaceuticals.

Seimbille Y, Rousseau J, Bénard F, Morin C, Ali H, Avvakumov G, Hammond GL, van Lier JE.

Steroids. 2002 Aug;67(9):765-75.

PMID:
12123788
17.

Steroid ligands bind human sex hormone-binding globulin in specific orientations and produce distinct changes in protein conformation.

Grishkovskaya I, Avvakumov GV, Hammond GL, Catalano MG, Muller YA.

J Biol Chem. 2002 Aug 30;277(35):32086-93. Epub 2002 Jun 13.

18.

Resolution of a disordered region at the entrance of the human sex hormone-binding globulin steroid-binding site.

Grishkovskaya I, Avvakumov GV, Hammond GL, Muller YA.

J Mol Biol. 2002 May 3;318(3):621-6.

PMID:
12054810
19.

O-Glycosylation of human sex hormone-binding globulin is essential for inhibition of estradiol-induced MCF-7 breast cancer cell proliferation.

Raineri M, Catalano MG, Hammond GL, Avvakumov GV, Frairia R, Fortunati N.

Mol Cell Endocrinol. 2002 Mar 28;189(1-2):135-43.

PMID:
12039072
20.

Resolution of the human sex hormone-binding globulin dimer interface and evidence for two steroid-binding sites per homodimer.

Avvakumov GV, Grishkovskaya I, Muller YA, Hammond GL.

J Biol Chem. 2001 Sep 14;276(37):34453-7. Epub 2001 Jul 16.

21.
22.

Crystal structure of human sex hormone-binding globulin: steroid transport by a laminin G-like domain.

Grishkovskaya I, Avvakumov GV, Sklenar G, Dales D, Hammond GL, Muller YA.

EMBO J. 2000 Feb 15;19(4):504-12.

23.

Crystallization of the N-terminal domain of human sex hormone-binding globulin, the major sex steroid carrier in blood.

Grishkovskaya I, Sklenar G, Avvakumov GV, Dales D, Behlke J, Hammond GL, Muller YA.

Acta Crystallogr D Biol Crystallogr. 1999 Dec;55(Pt 12):2053-5.

PMID:
10666590
24.

Novel human corticosteroid-binding globulin variant with low cortisol-binding affinity.

Emptoz-Bonneton A, Cousin P, Seguchi K, Avvakumov GV, Bully C, Hammond GL, Pugeat M.

J Clin Endocrinol Metab. 2000 Jan;85(1):361-7.

PMID:
10634411
25.

N-glycans are not the signal for apical sorting of corticosteroid binding globulin in MDCK cells.

Larsen JE, Avvakumov GV, Hammond GL, Vogel LK.

FEBS Lett. 1999 May 14;451(1):19-22.

26.

Structure and function of corticosteroid-binding globulin: role of carbohydrates.

Avvakumov GV.

J Steroid Biochem Mol Biol. 1995 Jun;53(1-6):515-22.

PMID:
7626503
27.
29.

Glycosylation of human corticosteroid-binding globulin at aspargine 238 is necessary for steroid binding.

Avvakumov GV, Warmels-Rodenhiser S, Hammond GL.

J Biol Chem. 1993 Jan 15;268(2):862-6.

30.

A transcortin-binding protein in the plasma membrane of human syncytiotrophoblast.

Krupenko SA, Avvakumov GV, Strel'chyonok OA.

Biochem Biophys Res Commun. 1991 Jun 14;177(2):834-9.

PMID:
1646610
31.

On the functional form of transcortin-recognizing subunit of transcortin membrane receptor.

Krupenko SA, Avvakumov GV, Strel'chyonok OA.

FEBS Lett. 1991 Apr 9;281(1-2):152-4.

32.

Interaction of human CBG with cell membranes.

Strel'chyonok OA, Avvakumov GV.

J Steroid Biochem Mol Biol. 1991;40(4-6):795-803.

PMID:
1659892
33.

Transcortin does not restrict the transmembrane transfer of cortisol.

Kisseleva EP, Vashkevich II, Avvakumov GV, Strel'chyonok OA.

Biochem Biophys Res Commun. 1990 Dec 31;173(3):961-6.

PMID:
2268356
34.

Binding of human sex hormone-binding globulin-androgen complexes to the placental syncytiotrophoblast membrane.

Krupenko NI, Avvakumov GV, Strel'chyonok OA.

Biochem Biophys Res Commun. 1990 Sep 28;171(3):1279-83.

PMID:
2222443
35.

Specific steroid-binding glycoproteins of human blood plasma: novel data on their structure and function.

Strel'chyonok OA, Avvakumov GV.

J Steroid Biochem. 1990 Apr;35(5):519-34. Review. No abstract available.

PMID:
2192196
36.

Study of the transcortin binding to human endometrium plasma membrane.

Avvakumov GV, Krupenko SA, Strel'chyonok OA.

Biochim Biophys Acta. 1989 Sep 4;984(2):143-50.

PMID:
2765544
37.

[Characteristics of a transcortin-binding component of the plasma membrane of cells of the human decidual endometrium].

Avvakumov GV, Krupenko SA, Strel'chenok OA.

Biokhimiia. 1989 Aug;54(8):1373-8. Russian.

PMID:
2819107
38.

[Variety of transcortin in the blood of women during normal pregnancy].

Avvakumov GV, Vashkevich II, Matseentseva IV, Vrubel' SV.

Probl Endokrinol (Mosk). 1988 Sep-Oct;34(5):32-5. Russian.

PMID:
3217385
39.

[Biological function of the carbohydrate component of human sex hormone-binding globulin].

Avvakumov GV, Zhuk NI, Strel'chenok OA.

Biokhimiia. 1988 May;53(5):838-41. Russian.

PMID:
3167126
40.

[Interaction of the transcortin-progesterone complex with plasma membranes of human decidual epithelium].

Avvakumov GV, Krupenko SA, Dubovskaia LV, Strel'chenok OA.

Biokhimiia. 1988 Apr;53(4):586-90. Russian.

PMID:
3395639
41.

[Pregnancy-associated variant of transcortin in humans].

Avvakumov GV, Matveentseva IV, Vashkevich II, Vrubel' SV.

Vopr Med Khim. 1988 Mar-Apr;34(2):49-53. Russian.

PMID:
3135668
43.

Properties and serum levels of pregnancy-associated variant of human transcortin.

Avvakumov GV, Strel'chyonok OA.

Biochim Biophys Acta. 1987 Jul 16;925(1):11-6.

PMID:
3593767
44.

[Radioimmunologic system for quantitative determination of transcortin in human blood serum].

Avvakumov GV, Vashkevich II, Vrubel' SV.

Med Radiol (Mosk). 1987 May;32(5):66-71. Russian. No abstract available.

PMID:
3586929
45.

Subcellular distribution and selectivity of the protein-binding component of the recognition system for sex-hormone-binding protein-estradiol complex in human decidual endometrium.

Avvakumov GV, Zhuk NI, Strel'chyonok OA.

Biochim Biophys Acta. 1986 May 2;881(3):489-98. Erratum in: Biochim Biophys Acta 1986 Jun 3;882(1):143.

PMID:
3697379
46.

[Interaction of blood sex steroid-binding globulin with cell membranes of human decidual tissue].

Avvakumov GV, Survilo LI, Strel'chenok OA.

Biokhimiia. 1985 Jul;50(7):1155-61. Russian.

PMID:
4041494
47.

[Interaction of blood sex steroid-binding globulin-steroid complexes with plasma membranes of human decidual endometrium cells].

Zhuk NI, Avvakumov GV, Strel'chenok OA.

Biokhimiia. 1985 Jul;50(7):1105-7. Russian.

PMID:
4041491
49.

A recognition system for sex-hormone-binding protein-estradiol complex in human decidual endometrium plasma membranes.

Strel'chyonok OA, Avvakumov GV, Survilo LI.

Biochim Biophys Acta. 1984 Dec 20;802(3):459-66.

PMID:
6542426
50.

[Comparative study of human transcortin isolated from normal donor blood and retroplacental blood].

Vashkevich II, Matveentseva IV, Avvakumov GV, Strel'chenok OA.

Biokhimiia. 1984 Dec;49(12):1977-85. Russian.

PMID:
6525368

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